REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 C3 Complement C3 [1] -0.40[2] -0.09[3] -1.43[4] -5.31[5] -1.45[6] 0.70[7]
2 TXN Thioredoxin [8] -1.94[9] -2.24[10] -1.53[11] -0.39[12] -0.98[13] -3.91[14]
3 HSP90AB1 Heat shock protein HSP 90-beta [15] 1.20[16] 0.94[17] 1.32[18] 1.53[19] 0.77[20] -2.74[21]
4 APP Amyloid-beta A4 protein [22] 1.35[23] 0.45[24] 2.28[25] 2.85[26] 3.13[27] -0.51[28]
5 HMOX1 Heme oxygenase 1 [29] 0.49[30] -0.79[31] -0.72[32] 0.48[33] 0.10[34] -2.73[35]
6 SUGT1 Protein SGT1 homolog [36] -0.63[37] -0.51[38] 0.81[39] 0.66[40] 0.46[41] -2.58[42]
7 GSDMD Gasdermin-D [43] -0.95[44] -0.48[45] 0.03[46] 0.81[47] -0.39[48] -1.30[49]
8 NFKB2 Nuclear factor NF-kappa-B p100 subunit [50] 0.21[51] 0.15[52] 1.78[53] 0.70[54] 1.41[55] -3.66[56]
9 RELA Transcription factor p65 [57] 1.11[58] 0.25[59] 1.56[60] 2.02[61] 1.79[62] -1.52[63]
10 IL18 Interleukin-18 [64] 0.11[65] -4.08[66] 1.23[67] 0.90[68] 0.10[69] -4.81[70]
11 TXNIP Thioredoxin-interacting protein [71] 1.84[72] 2.19[73] 3.99[74] 4.42[75] 4.29[76] 1.90[77]
12 ENTPD5 Ectonucleoside triphosphate diphosphohydrolase 5 [78] -0.65[79] 1.02[80] 1.12[81] -0.93[82] -0.52[83] 1.54[84]
13 P2RX4 P2X purinoceptor 4 [85] -0.03[86] -0.03[87] 1.67[88] 0.02[89] -0.32[90] -1.35[91]
14 NFKB1 Nuclear factor NF-kappa-B p105 subunit [92] 1.64[93] 0.97[94] 1.93[95] 1.83[96] 2.60[97] -0.19[98]
15 NT5E 5'-nucleotidase [99] -0.33[100] 2.79[101] 3.98[102] 1.40[103] 3.26[104] 0.74[105]
16 CASP1 Caspase-1 [106] -2.06[107] -5.81[108] -3.10[109] 2.16[110] 2.17[111] -1.38[112]
17 IL1B Interleukin-1 beta [113] -7.72[114] -7.94[115] -2.44[116] -1.51[117] 3.94[118] -5.84[119]
18 PYCARD Apoptosis-associated speck-like protein containing a CARD [120] 1.03[121] 0.86[122] -7.02[123] -6.16[124] 2.27[125] -1.48[126]
19 P2RX7 P2X purinoceptor 7 [127] -3.90[128] -0.97[129] -4.39[130] -3.29[131] 1.77[132] 0.47[133]
20 C3AR1 C3a anaphylatoxin chemotactic receptor [134] -5.11[135] [136] -6.56[137] 0.01[138] 2.52[139] 0.40[140]
21 CTSG Cathepsin G [141] [142] [143] [144] [145] [146] -2.81[147]
22 ENTPD1 Ectonucleoside triphosphate diphosphohydrolase 1 [148] 3.71[149] 4.10[150] 4.90[151] 3.64[152] 4.80[153] 2.60[154]
23 MEFV Pyrin [155] 0.03[156] 0.50[157] 1.13[158] 1.45[159] 1.27[160] 0.60[161]
24 PSTPIP1 Proline-serine-threonine phosphatase-interacting protein 1 [162] 1.21[163] 2.58[164] [165] -2.21[166] 2.30[167] 0.03[168]
25 NLRP3 NACHT, LRR and PYD domains-containing protein 3 [169] -2.66[170] -0.78[171] -1.40[172] 0.69[173] 3.03[174] 0.95[175]
26 IL1A Interleukin-1 alpha [176] 0.55[177] -0.21[178] -0.20[179] 1.44[180] 8.05[181] -2.23[182]
[1]
ref_hepatocyte C3
Mean 1.55e+03
Standard deviation 1.9e+03
Values 4.5e+02 72 1e+02 2.9e+03 4.2e+03
[2]
HepG2 C3
Mean 1.32e+03
Standard deviation 2.8e+02
Values 1.5e+03 1.1e+03
[3]
HepG2.C3A C3
Mean 1.86e+03
Standard deviation 1.1e+03
Values 2.6e+03 1.1e+03
[4]
HuH.7 C3
Mean 310
Standard deviation 1.5e+02
Values 2.5e+02 4.8e+02 2e+02
[5]
SNU475 C3
Mean 17
Standard deviation 4.7
Values 14 20
[6]
THLE C3
Mean 304
Standard deviation 27
Values 2.8e+02 3.2e+02
[7]
liver C3
Mean 5.59e+03
Standard deviation 1.3e+03
Values 3.7e+03 6.1e+03 6.5e+03 6.1e+03
[8]
ref_hepatocyte TXN
Mean 524
Standard deviation 4.3e+02
Values 6.9e+02 1.2e+03 2.7e+02 2.4e+02 2e+02
[9]
HepG2 TXN
Mean 153
Standard deviation 27
Values 1.7e+02 1.3e+02
[10]
HepG2.C3A TXN
Mean 142
Standard deviation 55
Values 1e+02 1.8e+02
[11]
HuH.7 TXN
Mean 98.2
Standard deviation 36
Values 91 67 1.4e+02
[12]
SNU475 TXN
Mean 174
Standard deviation 25
Values 1.9e+02 1.6e+02
[13]
THLE TXN
Mean 143
Standard deviation 0.49
Values 1.4e+02 1.4e+02
[14]
liver TXN
Mean 77.5
Standard deviation 77
Values 1.5e+02 16 1.3e+02 7.5
[15]
ref_hepatocyte HSP90AB1
Mean 469
Standard deviation 3.2e+02
Values 8.1e+02 7.8e+02 4e+02 2.1e+02 1.4e+02
[16]
HepG2 HSP90AB1
Mean 1.22e+03
Standard deviation 89
Values 1.2e+03 1.3e+03
[17]
HepG2.C3A HSP90AB1
Mean 1.16e+03
Standard deviation 1.2e+02
Values 1.2e+03 1.1e+03
[18]
HuH.7 HSP90AB1
Mean 634
Standard deviation 9.5
Values 6.3e+02 6.2e+02 6.4e+02
[19]
SNU475 HSP90AB1
Mean 591
Standard deviation 65
Values 5.4e+02 6.4e+02
[20]
THLE HSP90AB1
Mean 431
Standard deviation 80
Values 3.7e+02 4.9e+02
[21]
liver HSP90AB1
Mean 156
Standard deviation 26
Values 1.5e+02 1.4e+02 1.9e+02 1.3e+02
[22]
ref_hepatocyte APP
Mean 58.3
Standard deviation 28
Values 31 1e+02 46 51 59
[23]
HepG2 APP
Mean 167
Standard deviation 49
Values 2e+02 1.3e+02
[24]
HepG2.C3A APP
Mean 102
Standard deviation 27
Values 1.2e+02 83
[25]
HuH.7 APP
Mean 154
Standard deviation 13
Values 1.6e+02 1.7e+02 1.4e+02
[26]
SNU475 APP
Mean 184
Standard deviation 28
Values 2e+02 1.6e+02
[27]
THLE APP
Mean 273
Standard deviation 68
Values 2.3e+02 3.2e+02
[28]
liver APP
Mean 91
Standard deviation 73
Values 32 1.7e+02 28 1.3e+02
[29]
ref_hepatocyte HMOX1
Mean 45.4
Standard deviation 44
Values 19 4.5 1.2e+02 47 37
[30]
HepG2 HMOX1
Mean 71.8
Standard deviation 29
Values 92 52
[31]
HepG2.C3A HMOX1
Mean 33.6
Standard deviation 4.7
Values 30 37
[32]
HuH.7 HMOX1
Mean 14.9
Standard deviation 6.3
Values 10 22 12
[33]
SNU475 HMOX1
Mean 27.6
Standard deviation 4.6
Values 24 31
[34]
THLE HMOX1
Mean 26.2
Standard deviation 9.7
Values 19 33
[35]
liver HMOX1
Mean 15.2
Standard deviation 2.1
Values 16 13 18 15
[36]
ref_hepatocyte SUGT1
Mean 24.1
Standard deviation 16
Values 25 52 17 15 12
[37]
HepG2 SUGT1
Mean 17.5
Standard deviation 5.9
Values 13 22
[38]
HepG2.C3A SUGT1
Mean 21.7
Standard deviation 4.7
Values 18 25
[39]
HuH.7 SUGT1
Mean 23
Standard deviation 0.71
Values 22 23 24
[40]
SNU475 SUGT1
Mean 16.7
Standard deviation 0.19
Values 17 17
[41]
THLE SUGT1
Mean 17.8
Standard deviation 1.7
Values 17 19
[42]
liver SUGT1
Mean 8.95
Standard deviation 4
Values 13 6.1 12 5
[43]
ref_hepatocyte GSDMD
Mean 24
Standard deviation 21
Values 5.5 9.4 14 55 36
[44]
HepG2 GSDMD
Mean 14
Standard deviation 2.3
Values 12 16
[45]
HepG2.C3A GSDMD
Mean 22
Standard deviation 2.9
Values 24 20
[46]
HuH.7 GSDMD
Mean 13.3
Standard deviation 4.2
Values 14 8.8 17
[47]
SNU475 GSDMD
Mean 18.4
Standard deviation 3.2
Values 21 16
[48]
THLE GSDMD
Mean 9.83
Standard deviation 1.7
Values 11 8.6
[49]
liver GSDMD
Mean 21.7
Standard deviation 5.3
Values 29 16 19 23
[50]
ref_hepatocyte NFKB2
Mean 16.8
Standard deviation 20
Values 3.6 24 49 4.1 3
[51]
HepG2 NFKB2
Mean 21.8
Standard deviation 8.1
Values 28 16
[52]
HepG2.C3A NFKB2
Mean 23.9
Standard deviation 12
Values 32 16
[53]
HuH.7 NFKB2
Mean 31.3
Standard deviation 3.8
Values 29 36 29
[54]
SNU475 NFKB2
Mean 11.9
Standard deviation 3
Values 9.7 14
[55]
THLE NFKB2
Mean 24
Standard deviation 2.2
Values 22 26
[56]
liver NFKB2
Mean 2.95
Standard deviation 1.2
Values 2.1 3.3 1.8 4.5
[57]
ref_hepatocyte RELA
Mean 16
Standard deviation 11
Values 9.8 12 35 15 8.1
[58]
HepG2 RELA
Mean 38.7
Standard deviation 4.7
Values 42 35
[59]
HepG2.C3A RELA
Mean 24.3
Standard deviation 6.4
Values 29 20
[60]
HuH.7 RELA
Mean 25.6
Standard deviation 2.6
Values 29 25 23
[61]
SNU475 RELA
Mean 28.2
Standard deviation 0.33
Values 28 28
[62]
THLE RELA
Mean 29.7
Standard deviation 4
Values 27 32
[63]
liver RELA
Mean 12.3
Standard deviation 8.7
Values 19 4.1 20 5.7
[64]
ref_hepatocyte IL18
Mean 13.1
Standard deviation 19
Values 0 45 18 0.77 2
[65]
HepG2 IL18
Mean 15.9
Standard deviation 5.6
Values 20 12
[66]
HepG2.C3A IL18
Mean 0.993
Standard deviation 0.7
Values 0.5 1.5
[67]
HuH.7 IL18
Mean 16.7
Standard deviation 4.3
Values 13 21 16
[68]
SNU475 IL18
Mean 10.7
Standard deviation 5.7
Values 6.7 15
[69]
THLE IL18
Mean 7.57
Standard deviation 2
Values 6.2 9
[70]
liver IL18
Mean 1.04
Standard deviation 0.48
Values 1.4 0.56 1.5 0.7
[71]
ref_hepatocyte TXNIP
Mean 11
Standard deviation 11
Values 6.2 1.1 4.9 29 13
[72]
HepG2 TXNIP
Mean 44
Standard deviation 36
Values 69 19
[73]
HepG2.C3A TXNIP
Mean 64.3
Standard deviation 30
Values 85 43
[74]
HuH.7 TXNIP
Mean 94.3
Standard deviation 8.4
Values 86 1e+02 94
[75]
SNU475 TXNIP
Mean 102
Standard deviation 25
Values 84 1.2e+02
[76]
THLE TXNIP
Mean 115
Standard deviation 45
Values 1.5e+02 83
[77]
liver TXNIP
Mean 90.5
Standard deviation 29
Values 1.2e+02 66 65 1.1e+02
[78]
ref_hepatocyte ENTPD5
Mean 10.2
Standard deviation 5.5
Values 7.2 16 3 9.4 15
[79]
HepG2 ENTPD5
Mean 7.29
Standard deviation 3.7
Values 4.7 9.9
[80]
HepG2.C3A ENTPD5
Mean 26.4
Standard deviation 3.3
Values 24 29
[81]
HuH.7 ENTPD5
Mean 12
Standard deviation 3.7
Values 15 13 7.9
[82]
SNU475 ENTPD5
Mean 2.32
Standard deviation 1.1
Values 3.1 1.5
[83]
THLE ENTPD5
Mean 3.81
Standard deviation 1
Values 3.1 4.5
[84]
liver ENTPD5
Mean 65.6
Standard deviation 18
Values 51 90 52 70
[85]
ref_hepatocyte P2RX4
Mean 9.03
Standard deviation 6.7
Values 4.2 9 21 5.3 6
[86]
HepG2 P2RX4
Mean 9.97
Standard deviation 2
Values 11 8.5
[87]
HepG2.C3A P2RX4
Mean 11.3
Standard deviation 3.2
Values 14 9.1
[88]
HuH.7 P2RX4
Mean 15.6
Standard deviation 2.3
Values 13 18 15
[89]
SNU475 P2RX4
Mean 3.98
Standard deviation 1.7
Values 5.1 2.8
[90]
THLE P2RX4
Mean 3.9
Standard deviation 0.61
Values 4.3 3.5
[91]
liver P2RX4
Mean 7.87
Standard deviation 2.7
Values 9.9 5.2 11 5.9
[92]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 3 6.7 12 5.3 4.7
[93]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 18 26
[94]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 15 17
[95]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 14 12 13
[96]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 9.6 10
[97]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[98]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 9.7 15 7.2 17
[99]
ref_hepatocyte NT5E
Mean 5.59
Standard deviation 3.2
Values 0.3 5.8 8.3 5.6 8
[100]
HepG2 NT5E
Mean 5.01
Standard deviation 1.5
Values 4 6
[101]
HepG2.C3A NT5E
Mean 49.3
Standard deviation 7.9
Values 55 44
[102]
HuH.7 NT5E
Mean 47.8
Standard deviation 5.7
Values 53 42 49
[103]
SNU475 NT5E
Mean 6.43
Standard deviation 1.3
Values 5.5 7.4
[104]
THLE NT5E
Mean 28.7
Standard deviation 11
Values 21 36
[105]
liver NT5E
Mean 20.8
Standard deviation 5.2
Values 23 19 14 26
[106]
ref_hepatocyte CASP1
Mean 3.66
Standard deviation 3.7
Values 0.5 9.1 0.076 3.7 4.9
[107]
HepG2 CASP1
Mean 0.987
Standard deviation 0.74
Values 0.46 1.5
[108]
HepG2.C3A CASP1
Mean 0.0833
Standard deviation 0.049
Values 0.049 0.12
[109]
HuH.7 CASP1
Mean 0.231
Standard deviation 0.041
Values 0.19 0.27 0.23
[110]
SNU475 CASP1
Mean 7.12
Standard deviation 0.23
Values 7.3 6.9
[111]
THLE CASP1
Mean 8.87
Standard deviation 1.2
Values 9.7 8
[112]
liver CASP1
Mean 3.13
Standard deviation 0.99
Values 3.7 2.6 4.2 2
[113]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 0 0.08 13 2 0.76
[114]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.029 0.0043
[115]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0 0.032
[116]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.25 0.37 0.3
[117]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.32 0.62
[118]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[119]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.14 0.11 0.051 0.17
[120]
ref_hepatocyte PYCARD
Mean 2.47
Standard deviation 1.8
Values 0.17 2 2.3 2.7 5.2
[121]
HepG2 PYCARD
Mean 5.68
Standard deviation 3.5
Values 8.1 3.2
[122]
HepG2.C3A PYCARD
Mean 5.76
Standard deviation 0.0033
Values 5.8 5.8
[123]
HuH.7 PYCARD
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[124]
SNU475 PYCARD
Mean 0.015
Standard deviation 0.015
Values 0.0046 0.025
[125]
THLE PYCARD
Mean 6.42
Standard deviation 0.22
Values 6.3 6.6
[126]
liver PYCARD
Mean 1.97
Standard deviation 1.2
Values 3.3 0.9 2.7 0.99
[127]
ref_hepatocyte P2RX7
Mean 0.791
Standard deviation 1
Values 0.038 0.61 2.6 0.16 0.55
[128]
HepG2 P2RX7
Mean 0.0594
Standard deviation 0.029
Values 0.08 0.039
[129]
HepG2.C3A P2RX7
Mean 0.516
Standard deviation 0.27
Values 0.71 0.32
[130]
HuH.7 P2RX7
Mean 0.0205
Standard deviation 0.023
Values 0.0082 0.0064 0.047
[131]
SNU475 P2RX7
Mean 0.0353
Standard deviation 0.043
Values 0.0046 0.066
[132]
THLE P2RX7
Mean 1.45
Standard deviation 0.57
Values 1.9 1
[133]
liver P2RX7
Mean 2.43
Standard deviation 0.35
Values 2.6 2.6 2.6 1.9
[134]
ref_hepatocyte C3AR1
Mean 0.747
Standard deviation 0.72
Values 0 0 1.1 1.6 0.99
[135]
HepG2 C3AR1
Mean 0.0243
Standard deviation 0.022
Values 0.04 0.0086
[136]
HepG2.C3A C3AR1
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 C3AR1
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[138]
SNU475 C3AR1
Mean 0.327
Standard deviation 0.22
Values 0.17 0.48
[139]
THLE C3AR1
Mean 2.3
Standard deviation 0.24
Values 2.5 2.1
[140]
liver C3AR1
Mean 2.18
Standard deviation 0.93
Values 1.4 2.3 3.4 1.6
[141]
ref_hepatocyte CTSG
Mean 0.731
Standard deviation 1.1
Values 0 0 0 1.2 2.4
[142]
HepG2 CTSG
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A CTSG
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 CTSG
Mean 0
Standard deviation 0
Values 0 0 0
[145]
SNU475 CTSG
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE CTSG
Mean 0
Standard deviation 0
Values 0 0
[147]
liver CTSG
Mean 0.232
Standard deviation 0.29
Values 0.071 0.21 0.64 0
[148]
ref_hepatocyte ENTPD1
Mean 0.627
Standard deviation 0.48
Values 0.16 0.057 1 1 0.87
[149]
HepG2 ENTPD1
Mean 9.25
Standard deviation 1.7
Values 8.1 10
[150]
HepG2.C3A ENTPD1
Mean 13.8
Standard deviation 3
Values 12 16
[151]
HuH.7 ENTPD1
Mean 10.2
Standard deviation 3.7
Values 12 5.9 12
[152]
SNU475 ENTPD1
Mean 3.41
Standard deviation 0.91
Values 2.8 4.1
[153]
THLE ENTPD1
Mean 9.41
Standard deviation 0.61
Values 9.8 9
[154]
liver ENTPD1
Mean 8.46
Standard deviation 2.4
Values 5.6 11 7.4 10
[155]
ref_hepatocyte MEFV
Mean 0.361
Standard deviation 0.42
Values 1.1 0 0.4 0.1 0.25
[156]
HepG2 MEFV
Mean 0.414
Standard deviation 0.039
Values 0.44 0.39
[157]
HepG2.C3A MEFV
Mean 0.653
Standard deviation 0.17
Values 0.53 0.77
[158]
HuH.7 MEFV
Mean 0.43
Standard deviation 0.13
Values 0.39 0.58 0.32
[159]
SNU475 MEFV
Mean 0.429
Standard deviation 0.003
Values 0.43 0.43
[160]
THLE MEFV
Mean 0.467
Standard deviation 0.043
Values 0.5 0.44
[161]
liver MEFV
Mean 1.22
Standard deviation 1.1
Values 0.38 1.5 0.33 2.7
[162]
ref_hepatocyte PSTPIP1
Mean 0.267
Standard deviation 0.16
Values 0.32 0 0.45 0.3 0.27
[163]
HepG2 PSTPIP1
Mean 0.695
Standard deviation 0.03
Values 0.72 0.67
[164]
HepG2.C3A PSTPIP1
Mean 2.05
Standard deviation 0.68
Values 2.5 1.6
[165]
HuH.7 PSTPIP1
Mean 0
Standard deviation 0
Values 0 0 0
[166]
SNU475 PSTPIP1
Mean 0.0251
Standard deviation 0.029
Values 0.0046 0.046
[167]
THLE PSTPIP1
Mean 0.707
Standard deviation 0.26
Values 0.53 0.89
[168]
liver PSTPIP1
Mean 0.607
Standard deviation 0.18
Values 0.52 0.47 0.57 0.87
[169]
ref_hepatocyte NLRP3
Mean 0.117
Standard deviation 0.12
Values 0 0.11 0 0.28 0.19
[170]
HepG2 NLRP3
Mean 0.0207
Standard deviation 0.013
Values 0.011 0.03
[171]
HepG2.C3A NLRP3
Mean 0.0871
Standard deviation 0.013
Values 0.078 0.097
[172]
HuH.7 NLRP3
Mean 0.024
Standard deviation 0.036
Values 0 0.0064 0.066
[173]
SNU475 NLRP3
Mean 0.0819
Standard deviation 0.063
Values 0.037 0.13
[174]
THLE NLRP3
Mean 0.513
Standard deviation 0.15
Values 0.62 0.4
[175]
liver NLRP3
Mean 0.499
Standard deviation 0.28
Values 0.19 0.84 0.39 0.58
[176]
ref_hepatocyte IL1A
Mean 0.05
Standard deviation 0.11
Values 0 0 0.25 0 0
[177]
HepG2 IL1A
Mean 0.0823
Standard deviation 0.035
Values 0.057 0.11
[178]
HepG2.C3A IL1A
Mean 0.0555
Standard deviation 0.018
Values 0.068 0.043
[179]
HuH.7 IL1A
Mean 0.0235
Standard deviation 0.041
Values 0 0.071 0
[180]
SNU475 IL1A
Mean 0.0589
Standard deviation 0.024
Values 0.042 0.076
[181]
THLE IL1A
Mean 7.11
Standard deviation 1.8
Values 8.4 5.8
[182]
liver IL1A
Mean 0.0237
Standard deviation 0.034
Values 0.024 0.071 0 0