REACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.27[2] -0.34[3] -0.38[4] -0.39[5] -0.16[6] 0.06[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.17[16] 0.41[17] -0.02[18] 0.46[19] 0.21[20] 0.51[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.61[23] 2.65[24] 3.50[25] 1.86[26] 2.44[27] 1.28[28]
5 AKT1 RAC-alpha serine/threonine-protein kinase [29] 2.01[30] 1.91[31] 0.64[32] 2.34[33] 2.13[34] 1.69[35]
6 ARAP1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 4.08[36] 3.34[37] 2.66[38] 3.79[39] 3.06[40] 3.38[41]
7 DOK1 Docking protein 1 [42] 0.63[43] 0.36[44] 3.37[45] 2.65[46] 3.82[47] 1.66[48]
8 PTK6 Protein-tyrosine kinase 6 [49] 0.81[50] 3.15[51] 1.20[52] 0.73[53] 0.08[54] 1.36[55]
9 CBL E3 ubiquitin-protein ligase CBL [56] 6.38[57] 5.45[58] 5.48[59] 7.53[60] 6.77[61] 5.69[62]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[30]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[31]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[32]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[33]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[34]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[35]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[36]
ref_hepatocyte ARAP1
Mean 7.32
Standard deviation 4.6
Values 15 6.6 6.5 4 4.2
[37]
HepG2 ARAP1
Mean 71.6
Standard deviation 6.1
Values 76 67
[38]
HepG2.C3A ARAP1
Mean 34.8
Standard deviation 6
Values 39 31
[39]
HuH.7 ARAP1
Mean 23.9
Standard deviation 1.5
Values 24 25 22
[40]
SNU475 ARAP1
Mean 35.4
Standard deviation 10
Values 43 28
[41]
THLE ARAP1
Mean 28.2
Standard deviation 1.8
Values 27 30
[42]
liver ARAP1
Mean 28.3
Standard deviation 7.2
Values 26 24 24 39
[43]
ref_hepatocyte DOK1
Mean 0.979
Standard deviation 0.66
Values 0 1.8 1.3 0.85 0.94
[44]
HepG2 DOK1
Mean 0.879
Standard deviation 0.56
Values 1.3 0.48
[45]
HepG2.C3A DOK1
Mean 0.593
Standard deviation 0.096
Values 0.66 0.53
[46]
HuH.7 DOK1
Mean 5.23
Standard deviation 1.4
Values 4.9 4 6.7
[47]
SNU475 DOK1
Mean 2.15
Standard deviation 0.62
Values 2.6 1.7
[48]
THLE DOK1
Mean 6.37
Standard deviation 0.36
Values 6.1 6.6
[49]
liver DOK1
Mean 1.15
Standard deviation 0.17
Values 1.1 0.96 1.4 1.2
[50]
ref_hepatocyte PTK6
Mean 0.543
Standard deviation 0.59
Values 0 0.55 1.5 0.39 0.24
[51]
HepG2 PTK6
Mean 0.551
Standard deviation 0.28
Values 0.75 0.35
[52]
HepG2.C3A PTK6
Mean 2.27
Standard deviation 0.8
Values 2.8 1.7
[53]
HuH.7 PTK6
Mean 0.643
Standard deviation 0.082
Values 0.66 0.55 0.71
[54]
SNU475 PTK6
Mean 0.316
Standard deviation 0.047
Values 0.28 0.35
[55]
THLE PTK6
Mean 0.264
Standard deviation 0.02
Values 0.28 0.25
[56]
liver PTK6
Mean 0.517
Standard deviation 0.32
Values 0.12 0.64 0.44 0.87
[57]
ref_hepatocyte CBL
Mean 0.522
Standard deviation 0.26
Values 0.83 0.62 0.65 0.18 0.33
[58]
HepG2 CBL
Mean 25.2
Standard deviation 0.64
Values 26 25
[59]
HepG2.C3A CBL
Mean 10.8
Standard deviation 0.61
Values 11 10
[60]
HuH.7 CBL
Mean 12.1
Standard deviation 3
Values 15 11 9.5
[61]
SNU475 CBL
Mean 33.7
Standard deviation 5.1
Values 30 37
[62]
THLE CBL
Mean 26.4
Standard deviation 3.4
Values 24 29
[63]
liver CBL
Mean 10
Standard deviation 4.2
Values 5.8 14 7.1 14