REACTOME_PTK6_PROMOTES_HIF1A_STABILIZATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HIF1A Hypoxia-inducible factor 1-alpha [1] 0.16[2] 0.05[3] -0.29[4] 0.26[5] 0.19[6] -1.53[7]
2 EGFR Epidermal growth factor receptor [8] -0.38[9] -0.54[10] 1.21[11] -1.60[12] -1.43[13] 1.93[14]
3 HBEGF Proheparin-binding EGF-like growth factor [15] -0.67[16] -1.27[17] -3.47[18] -1.73[19] -2.49[20] -3.15[21]
4 GPNMB Transmembrane glycoprotein NMB [22] -0.56[23] 0.67[24] -0.09[25] 0.38[26] 0.83[27] -0.60[28]
5 PTK6 Protein-tyrosine kinase 6 [29] -0.81[30] 1.62[31] -1.28[32] -3.69[33] -4.56[34] -1.30[35]
6 LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 [36] [37] -4.31[38] [39] -2.60[40] 1.07[41] 3.92[42]
[1]
ref_hepatocyte HIF1A
Mean 26.5
Standard deviation 22
Values 27 61 30 8.1 5.8
[2]
HepG2 HIF1A
Mean 52.5
Standard deviation 22
Values 37 68
[3]
HepG2.C3A HIF1A
Mean 37.2
Standard deviation 10
Values 30 44
[4]
HuH.7 HIF1A
Mean 62
Standard deviation 17
Values 81 55 49
[5]
SNU475 HIF1A
Mean 237
Standard deviation 65
Values 2.8e+02 1.9e+02
[6]
THLE HIF1A
Mean 346
Standard deviation 60
Values 3.9e+02 3e+02
[7]
liver HIF1A
Mean 21.5
Standard deviation 8.5
Values 12 25 18 31
[8]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[9]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[10]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[11]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[12]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[13]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[14]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[15]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 1 3.1 3.8 0.78 0.34
[16]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 2.1 1.9
[17]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 1.2 0.82
[18]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.52 0.43 0.46
[19]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 3.9 4.4
[20]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[21]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.89 0.27 0.28 0.46
[22]
ref_hepatocyte GPNMB
Mean 1.81
Standard deviation 0.43
Values 1.8 1.5 1.5 1.8 2.5
[23]
HepG2 GPNMB
Mean 2.17
Standard deviation 0.21
Values 2.3 2
[24]
HepG2.C3A GPNMB
Mean 3.9
Standard deviation 2.1
Values 2.4 5.4
[25]
HuH.7 GPNMB
Mean 4.87
Standard deviation 1.4
Values 3.2 5.8 5.6
[26]
SNU475 GPNMB
Mean 17.7
Standard deviation 4
Values 15 21
[27]
THLE GPNMB
Mean 36.7
Standard deviation 20
Values 23 51
[28]
liver GPNMB
Mean 2.79
Standard deviation 0.55
Values 3 3.4 2.6 2.1
[29]
ref_hepatocyte PTK6
Mean 0.543
Standard deviation 0.59
Values 0 0.55 1.5 0.39 0.24
[30]
HepG2 PTK6
Mean 0.551
Standard deviation 0.28
Values 0.75 0.35
[31]
HepG2.C3A PTK6
Mean 2.27
Standard deviation 0.8
Values 2.8 1.7
[32]
HuH.7 PTK6
Mean 0.643
Standard deviation 0.082
Values 0.66 0.55 0.71
[33]
SNU475 PTK6
Mean 0.316
Standard deviation 0.047
Values 0.28 0.35
[34]
THLE PTK6
Mean 0.264
Standard deviation 0.02
Values 0.28 0.25
[35]
liver PTK6
Mean 0.517
Standard deviation 0.32
Values 0.12 0.64 0.44 0.87
[36]
ref_hepatocyte LRRK2
Mean 0.305
Standard deviation 0.37
Values 0 0.18 0.19 0.22 0.94
[37]
HepG2 LRRK2
Mean 0
Standard deviation 0
Values 0 0
[38]
HepG2.C3A LRRK2
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[39]
HuH.7 LRRK2
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 LRRK2
Mean 0.376
Standard deviation 0.045
Values 0.41 0.34
[41]
THLE LRRK2
Mean 7.31
Standard deviation 4.6
Values 11 4
[42]
liver LRRK2
Mean 10.8
Standard deviation 7.1
Values 6.9 14 3.1 19