REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FLOT1 | Flotillin-1 | [1] | -1.15[2] | -0.52[3] | -1.53[4] | -0.55[5] | -1.11[6] | -2.28[7] |
2 | FLOT2 | Flotillin-2 | [8] | -1.05[9] | -1.00[10] | -0.99[11] | -1.11[12] | -1.12[13] | -0.48[14] |
3 | RTN3 | Reticulon-3 | [15] | -1.10[16] | -0.86[17] | -0.26[18] | -0.09[19] | 0.16[20] | -1.48[21] |
4 | DBNL | Drebrin-like protein | [22] | -0.98[23] | -1.44[24] | -2.14[25] | -0.72[26] | -0.64[27] | -1.71[28] |
5 | PTPRF | Receptor-type tyrosine-protein phosphatase F | [29] | 1.64[30] | 0.79[31] | 1.70[32] | 0.18[33] | 0.79[34] | 1.39[35] |
6 | HOMER2 | Homer protein homolog 2 | [36] | -3.43[37] | -3.02[38] | -10.95[39] | -4.10[40] | -5.11[41] | -1.92[42] |
7 | PDLIM5 | PDZ and LIM domain protein 5 | [43] | -0.16[44] | 0.14[45] | 0.18[46] | 0.19[47] | 0.70[48] | 0.69[49] |
8 | IL1RAP | Interleukin-1 receptor accessory protein | [50] | -2.02[51] | 0.32[52] | -0.41[53] | -2.22[54] | -0.85[55] | 1.16[56] |
9 | EPB41L2 | Band 4.1-like protein 2 | [57] | -0.01[58] | 1.08[59] | 0.38[60] | 0.75[61] | 0.57[62] | -1.30[63] |
10 | DLGAP4 | Disks large-associated protein 4 | [64] | 0.64[65] | -0.16[66] | -0.83[67] | -0.15[68] | -0.50[69] | -2.04[70] |
11 | SHARPIN | Sharpin | [71] | -0.80[72] | -0.83[73] | -1.18[74] | -0.67[75] | -0.91[76] | -1.32[77] |
12 | EPB41L5 | Band 4.1-like protein 5 | [78] | -0.65[79] | 0.48[80] | 0.56[81] | -1.72[82] | -0.75[83] | 1.21[84] |
13 | EPB41 | Protein 4.1 | [85] | 0.17[86] | 0.30[87] | 0.76[88] | -0.51[89] | -1.23[90] | 0.42[91] |
14 | LIN7A | Protein lin-7 homolog A | [92] | -2.06[93] | -1.67[94] | -1.27[95] | -5.51[96] | -5.53[97] | -1.83[98] |
15 | DLG1 | Disks large homolog 1 | [99] | 0.54[100] | 1.00[101] | 0.50[102] | 0.55[103] | 0.84[104] | 0.28[105] |
16 | LIN7C | Protein lin-7 homolog C | [106] | -0.91[107] | 0.37[108] | 1.33[109] | -0.93[110] | -0.55[111] | 1.53[112] |
17 | PPFIBP2 | Liprin-beta-2 | [113] | -0.78[114] | 0.14[115] | -0.65[116] | -3.02[117] | -3.75[118] | 0.38[119] |
18 | PPFIA1 | Liprin-alpha-1 | [120] | 1.07[121] | 0.95[122] | 1.42[123] | 3.43[124] | 1.44[125] | 0.80[126] |
19 | APBA3 | Amyloid-beta A4 precursor protein-binding family A member 3 | [127] | -0.98[128] | -0.86[129] | -0.90[130] | -1.82[131] | -0.89[132] | -1.37[133] |
20 | PPFIBP1 | Liprin-beta-1 | [134] | 0.61[135] | 0.62[136] | 1.04[137] | 1.69[138] | 1.94[139] | 1.38[140] |
21 | SYT7 | Synaptotagmin-7 | [141] | -0.67[142] | -1.24[143] | -1.64[144] | -4.92[145] | -3.14[146] | 2.59[147] |
22 | SIPA1L1 | Signal-induced proliferation-associated 1-like protein 1 | [148] | 1.09[149] | 1.18[150] | 0.76[151] | -0.07[152] | 2.36[153] | 1.70[154] |
23 | HOMER3 | Homer protein homolog 3 | [155] | 1.03[156] | 0.95[157] | 0.51[158] | 0.54[159] | 1.08[160] | -3.57[161] |
24 | SYT12 | Synaptotagmin-12 | [162] | -4.46[163] | -5.51[164] | 0.43[165] | -0.50[166] | -3.48[167] | -1.33[168] |
25 | CASK | Peripheral plasma membrane protein CASK | [169] | 1.28[170] | 1.29[171] | 2.46[172] | 2.16[173] | 1.74[174] | 0.23[175] |
26 | GRIA3 | Glutamate receptor 3 | [176] | -8.97[177] | -7.71[178] | 0.21[179] | -8.70[180] | -2.87[181] | -1.82[182] |
27 | EPB41L1 | Band 4.1-like protein 1 | [183] | 3.74[184] | 2.07[185] | -0.94[186] | 2.37[187] | 1.53[188] | 0.07[189] |
28 | APBA1 | Amyloid-beta A4 precursor protein-binding family A member 1 | [190] | -7.94[191] | -8.07[192] | 0.60[193] | -2.86[194] | -3.17[195] | 1.32[196] |
29 | PTPRS | Receptor-type tyrosine-protein phosphatase S | [197] | 3.57[198] | 2.63[199] | -5.85[200] | 1.90[201] | 2.90[202] | 1.95[203] |
30 | LRFN3 | Leucine-rich repeat and fibronectin type-III domain-containing protein 3 | 0.03[204] | -0.70[205] | 0.05[206] | -0.34[207] | 0.02[208] | -1.67[209] | |
31 | HOMER1 | Homer protein homolog 1 | [210] | 0.90[211] | 1.96[212] | 2.31[213] | 0.77[214] | 0.77[215] | -1.55[216] |
32 | LIN7B | Protein lin-7 homolog B | [217] | -1.13[218] | -0.42[219] | -1.39[220] | -1.51[221] | -1.62[222] | -2.71[223] |
33 | SLITRK3 | SLIT and NTRK-like protein 3 | [224] | -9.30[225] | -5.97[226] | -5.51[227] | -10.02[228] | -6.57[229] | 0.27[230] |
34 | NRXN2 | Neurexin-2 | [231] | -3.96[232] | -5.15[233] | -8.24[234] | -1.69[235] | -5.46[236] | -2.47[237] |
35 | SYT9 | Synaptotagmin-9 | [238] | -8.95[239] | -7.71[240] | [241] | -4.92[242] | -7.71[243] | 1.08[244] |
36 | STX1A | Syntaxin-1A | [245] | 0.41[246] | 0.50[247] | -1.37[248] | 1.84[249] | 1.13[250] | -2.19[251] |
37 | STXBP1 | Syntaxin-binding protein 1 | [252] | 1.21[253] | 1.73[254] | 1.78[255] | 3.44[256] | 3.58[257] | -0.19[258] |
38 | SHANK2 | SH3 and multiple ankyrin repeat domains protein 2 | [259] | 3.54[260] | 2.58[261] | 2.94[262] | -0.41[263] | -4.25[264] | 3.22[265] |
39 | NLGN2 | Neuroligin-2 | [266] | 1.58[267] | 3.71[268] | 3.24[269] | 2.64[270] | 3.48[271] | -0.85[272] |
40 | PPFIA3 | Liprin-alpha-3 | [273] | 2.19[274] | 2.73[275] | 2.34[276] | 0.14[277] | 0.01[278] | -0.95[279] |
41 | DLG3 | Disks large homolog 3 | [280] | 3.04[281] | 2.75[282] | -5.56[283] | 1.29[284] | 2.90[285] | -0.48[286] |
42 | PTPRD | Receptor-type tyrosine-protein phosphatase delta | [287] | -5.44[288] | -7.84[289] | [290] | -7.67[291] | -1.05[292] | 3.02[293] |
43 | LRFN4 | Leucine-rich repeat and fibronectin type-III domain-containing protein 4 | 2.10[294] | 1.11[295] | -2.25[296] | -3.13[297] | 2.48[298] | 1.19[299] | |
44 | NLGN4Y | Neuroligin-4, Y-linked | [300] | 0.43[301] | 1.19[302] | [303] | [304] | [305] | 0.10[306] |
45 | EPB41L3 | Band 4.1-like protein 3 | [307] | -5.03[308] | -5.76[309] | 2.73[310] | -1.94[311] | 4.18[312] | 1.86[313] |
46 | DLG4 | Disks large homolog 4 | [314] | 2.26[315] | 2.66[316] | 1.04[317] | 1.20[318] | 3.70[319] | 0.67[320] |
47 | LRFN1 | Leucine-rich repeat and fibronectin type III domain-containing protein 1 | 0.45[321] | -4.32[322] | 1.45[323] | 0.25[324] | 1.55[325] | -1.49[326] | |
48 | IL1RAPL2 | X-linked interleukin-1 receptor accessory protein-like 2 | [327] | [328] | [329] | -8.01[330] | -3.14[331] | -4.65[332] | 0.59[333] |
49 | NLGN4X | Neuroligin-4, X-linked | [334] | -7.17[335] | [336] | [337] | -1.55[338] | -5.08[339] | 2.06[340] |
50 | DLG2 | Disks large homolog 2 | [341] | -2.15[342] | -1.78[343] | -1.10[344] | -1.46[345] | -2.08[346] | 1.70[347] |
51 | GRIN2D | Glutamate receptor ionotropic, NMDA 2D | [348] | 3.96[349] | 3.97[350] | 3.92[351] | 2.03[352] | 1.27[353] | -1.08[354] |
52 | NRXN3 | Neurexin-3 | [355] | 0.42[356] | 1.10[357] | 4.50[358] | 0.41[359] | 3.54[360] | 1.29[361] |
53 | APBA2 | Amyloid-beta A4 precursor protein-binding family A member 2 | [362] | 5.03[363] | 1.19[364] | 4.75[365] | 5.80[366] | 5.74[367] | 2.72[368] |
54 | SYT1 | Synaptotagmin-1 | [369] | -2.62[370] | -3.26[371] | 5.00[372] | 6.43[373] | 2.89[374] | 3.19[375] |
55 | DLGAP3 | Disks large-associated protein 3 | [376] | -0.68[377] | -4.31[378] | -1.35[379] | -1.29[380] | 0.41[381] | 0.07[382] |
56 | NTRK3 | NT-3 growth factor receptor | [383] | [384] | [385] | [386] | 3.01[387] | -1.25[388] | 2.82[389] |
57 | SYT2 | Synaptotagmin-2 | [390] | -0.18[391] | 1.29[392] | 3.78[393] | 4.48[394] | 0.68[395] | 3.61[396] |
58 | LRRTM4 | Leucine-rich repeat transmembrane neuronal protein 4 | [397] | -0.13[398] | 1.84[399] | 1.82[400] | -4.06[401] | -3.66[402] | -0.21[403] |
59 | GRIN2B | Glutamate receptor ionotropic, NMDA 2B | [404] | -2.98[405] | [406] | [407] | 0.33[408] | -2.19[409] | 0.83[410] |
60 | GRIA4 | Glutamate receptor 4 | [411] | [412] | -1.01[413] | 0.28[414] | 0.76[415] | 0.75[416] | 0.63[417] |
61 | DLGAP1 | Disks large-associated protein 1 | [418] | 0.31[419] | -0.50[420] | -2.58[421] | 2.44[422] | 0.48[423] | 1.29[424] |
62 | SLITRK4 | SLIT and NTRK-like protein 4 | [425] | 1.25[426] | 2.51[427] | 0.48[428] | 0.22[429] | 6.97[430] | 4.00[431] |
63 | SLITRK2 | SLIT and NTRK-like protein 2 | [432] | [433] | [434] | [435] | -1.69[436] | [437] | 2.99[438] |
64 | NLGN3 | Neuroligin-3 | [439] | 0.41[440] | 1.11[441] | 3.92[442] | 1.86[443] | 2.44[444] | 2.68[445] |
65 | LRRTM2 | Leucine-rich repeat transmembrane neuronal protein 2 | [446] | -3.59[447] | -0.09[448] | 0.07[449] | -0.09[450] | -1.01[451] | 7.18[452] |
66 | GRIA1 | Glutamate receptor 1 | [453] | -2.85[454] | [455] | [456] | -1.41[457] | -0.68[458] | -0.89[459] |
67 | GRIN2C | Glutamate receptor ionotropic, NMDA 2C | [460] | 3.06[461] | 4.83[462] | 3.06[463] | 2.73[464] | 3.65[465] | 2.91[466] |
68 | PPFIA2 | Liprin-alpha-2 | [467] | 3.66[468] | 6.70[469] | 5.65[470] | -0.03[471] | 0.67[472] | 5.87[473] |
69 | SLITRK5 | SLIT and NTRK-like protein 5 | [474] | -2.44[475] | -1.25[476] | [477] | -1.08[478] | 6.57[479] | -1.04[480] |
70 | NRXN1 | Neurexin-1 | [481] | -1.63[482] | -1.25[483] | [484] | -2.71[485] | -2.39[486] | 4.34[487] |
71 | DLGAP2 | Disks large-associated protein 2 | [488] | [489] | [490] | [491] | 0.70[492] | [493] | 5.09[494] |
72 | GRIN2A | Glutamate receptor ionotropic, NMDA 2A | [495] | [496] | [497] | -1.39[498] | 8.30[499] | 1.11[500] | 7.00[501] |
73 | GRM1 | Metabotropic glutamate receptor 1 | [502] | 1.73[503] | [504] | -0.37[505] | 4.82[506] | 2.84[507] | 2.10[508] |
74 | LRRC4B | Leucine-rich repeat-containing protein 4B | [509] | [510] | [511] | [512] | [513] | [514] | [515] |
75 | PPFIA4 | Liprin-alpha-4 | [516] | [517] | [518] | [519] | [520] | [521] | [522] |
76 | LRFN2 | Leucine-rich repeat and fibronectin type-III domain-containing protein 2 | [523] | [524] | [525] | [526] | [527] | [528] | |
77 | LRRTM3 | Leucine-rich repeat transmembrane neuronal protein 3 | [529] | [530] | [531] | [532] | [533] | [534] | [535] |
78 | BEGAIN | Brain-enriched guanylate kinase-associated protein | [536] | [537] | [538] | [539] | [540] | [541] | [542] |
79 | SLITRK1 | SLIT and NTRK-like protein 1 | [543] | [544] | [545] | [546] | [547] | [548] | [549] |
80 | SYT10 | Synaptotagmin-10 | [550] | [551] | [552] | [553] | [554] | [555] | [556] |
81 | SHANK1 | SH3 and multiple ankyrin repeat domains protein 1 | [557] | [558] | [559] | [560] | [561] | [562] | [563] |
82 | GRM5 | Metabotropic glutamate receptor 5 | [564] | [565] | [566] | [567] | [568] | [569] | [570] |
83 | IL1RAPL1 | Interleukin-1 receptor accessory protein-like 1 | [571] | [572] | [573] | [574] | [575] | [576] | [577] |
84 | LRRTM1 | Leucine-rich repeat transmembrane neuronal protein 1 | [578] | [579] | [580] | [581] | [582] | [583] | [584] |
85 | NLGN1 | Neuroligin-1 | [585] | [586] | [587] | [588] | [589] | [590] | [591] |
86 | GRIN1 | Glutamate receptor ionotropic, NMDA 1 | [592] | [593] | [594] | [595] | [596] | [597] | [598] |
87 | SLITRK6 | SLIT and NTRK-like protein 6 | [599] | [600] | [601] | [602] | [603] | [604] | [605] |