REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNAS Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas 0.48[1] 0.52[2] 0.28[3] 0.40[4] -0.11[5] -0.22[6]
2 GNG5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 -1.15[7] -0.97[8] -1.73[9] -2.26[10] -2.27[11] -0.47[12]
3 GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [13] 1.07[14] 1.09[15] 0.72[16] 0.83[17] 0.88[18] -0.12[19]
4 GNB2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [20] -0.55[21] -0.80[22] -0.35[23] -0.82[24] -0.50[25] -0.49[26]
5 GNG10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 -4.65[27] -4.36[28] -4.55[29] -4.26[30] -3.19[31] -3.23[32]
6 GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 -4.70[33] -7.63[34] 0.43[35] 1.43[36] 1.78[37] 1.60[38]
7 GNB5 Guanine nucleotide-binding protein subunit beta-5 [39] 0.15[40] 0.19[41] 1.32[42] 0.34[43] 0.71[44] 2.00[45]
8 GNG11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 -8.13[46] -8.12[47] -7.32[48] 1.81[49] 3.39[50] 3.35[51]
9 GNG7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 1.61[52] 1.26[53] 2.18[54] -2.69[55] -1.81[56] 1.14[57]
10 GNG4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 3.52[58] 1.29[59] 5.20[60] 0.81[61] -1.06[62] -1.44[63]
11 GNB4 Guanine nucleotide-binding protein subunit beta-4 [64] -0.31[65] 0.18[66] 1.29[67] 2.23[68] 5.22[69] 5.20[70]
12 GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 -6.23[71] -7.10[72] [73] 2.67[74] 2.39[75] 3.89[76]
13 GNGT2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [77] [78] [79] -2.52[80] -6.94[81] 1.22[82]
14 GNG3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 -0.80[83] 1.04[84] -1.09[85] -1.15[86] -1.21[87] 1.03[88]
15 GNB3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [89] 1.64[90] 3.90[91] 3.31[92] 0.56[93] 3.52[94] -0.57[95]
16 PTGIR Prostacyclin receptor [96] -0.95[97] -3.98[98] [99] -1.01[100] 3.61[101] 5.96[102]
17 GNGT1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 [103] [104] [105] [106] [107] [108] [109]
18 GNG13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [110] [111] [112] [113] [114] [115]
19 GNG8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [116] [117] [118] [119] [120] [121]
[1]
ref_hepatocyte GNAS
Mean 120
Standard deviation 56
Values 1.4e+02 60 61 1.7e+02 1.7e+02
[2]
HepG2 GNAS
Mean 357
Standard deviation 65
Values 4e+02 3.1e+02
[3]
HepG2.C3A GNAS
Mean 326
Standard deviation 53
Values 3.6e+02 2.9e+02
[4]
HuH.7 GNAS
Mean 246
Standard deviation 32
Values 2.5e+02 2.1e+02 2.7e+02
[5]
SNU475 GNAS
Mean 397
Standard deviation 89
Values 4.6e+02 3.3e+02
[6]
THLE GNAS
Mean 262
Standard deviation 20
Values 2.5e+02 2.8e+02
[7]
liver GNAS
Mean 67.5
Standard deviation 15
Values 84 54 76 56
[8]
ref_hepatocyte GNG5
Mean 71
Standard deviation 24
Values 60 35 85 91 85
[9]
HepG2 GNG5
Mean 68.1
Standard deviation 11
Values 60 76
[10]
HepG2.C3A GNG5
Mean 68.6
Standard deviation 10
Values 61 76
[11]
HuH.7 GNG5
Mean 36.1
Standard deviation 6.8
Values 38 28 42
[12]
SNU475 GNG5
Mean 37.2
Standard deviation 3.1
Values 39 35
[13]
THLE GNG5
Mean 34.8
Standard deviation 0.49
Values 34 35
[14]
liver GNG5
Mean 33.6
Standard deviation 38
Values 75 1.4 56 1.4
[15]
ref_hepatocyte GNB1
Mean 42.7
Standard deviation 15
Values 44 60 53 31 24
[16]
HepG2 GNB1
Mean 190
Standard deviation 15
Values 2e+02 1.8e+02
[17]
HepG2.C3A GNB1
Mean 171
Standard deviation 4.5
Values 1.7e+02 1.7e+02
[18]
HuH.7 GNB1
Mean 118
Standard deviation 23
Values 1.4e+02 93 1.2e+02
[19]
SNU475 GNB1
Mean 191
Standard deviation 19
Values 2e+02 1.8e+02
[20]
THLE GNB1
Mean 185
Standard deviation 12
Values 1.8e+02 1.9e+02
[21]
liver GNB1
Mean 25.7
Standard deviation 5
Values 31 25 19 27
[22]
ref_hepatocyte GNB2
Mean 38.8
Standard deviation 20
Values 15 25 41 67 46
[23]
HepG2 GNB2
Mean 56.5
Standard deviation 6.2
Values 61 52
[24]
HepG2.C3A GNB2
Mean 42.3
Standard deviation 7.9
Values 48 37
[25]
HuH.7 GNB2
Mean 51.2
Standard deviation 3.5
Values 50 49 55
[26]
SNU475 GNB2
Mean 55.4
Standard deviation 5.7
Values 59 51
[27]
THLE GNB2
Mean 64.6
Standard deviation 5.2
Values 61 68
[28]
liver GNB2
Mean 18.2
Standard deviation 7.1
Values 24 11 25 13
[29]
ref_hepatocyte GNG10
Mean 36.1
Standard deviation 25
Values 54 68 12 12 34
[30]
HepG2 GNG10
Mean 3.07
Standard deviation 0.45
Values 2.8 3.4
[31]
HepG2.C3A GNG10
Mean 3.33
Standard deviation 1.3
Values 2.4 4.3
[32]
HuH.7 GNG10
Mean 2.59
Standard deviation 0.11
Values 2.6 2.5 2.7
[33]
SNU475 GNG10
Mean 4.73
Standard deviation 1.4
Values 5.8 3.7
[34]
THLE GNG10
Mean 9.34
Standard deviation 0.66
Values 8.9 9.8
[35]
liver GNG10
Mean 2.53
Standard deviation 1.2
Values 3.6 2.1 3.3 1.1
[36]
ref_hepatocyte GNG12
Mean 16.5
Standard deviation 18
Values 0.58 46 23 5.6 7.3
[37]
HepG2 GNG12
Mean 1.35
Standard deviation 0.72
Values 1.9 0.84
[38]
HepG2.C3A GNG12
Mean 0.158
Standard deviation 0.011
Values 0.17 0.15
[39]
HuH.7 GNG12
Mean 37.3
Standard deviation 6.6
Values 44 36 31
[40]
SNU475 GNG12
Mean 111
Standard deviation 32
Values 1.3e+02 89
[41]
THLE GNG12
Mean 133
Standard deviation 28
Values 1.1e+02 1.5e+02
[42]
liver GNG12
Mean 32.7
Standard deviation 9.9
Values 36 32 43 19
[43]
ref_hepatocyte GNB5
Mean 4.79
Standard deviation 2.5
Values 6.3 6.9 2 6.5 2.2
[44]
HepG2 GNB5
Mean 11.3
Standard deviation 2.9
Values 13 9.2
[45]
HepG2.C3A GNB5
Mean 10.4
Standard deviation 1.2
Values 11 9.5
[46]
HuH.7 GNB5
Mean 20.1
Standard deviation 2.5
Values 20 23 18
[47]
SNU475 GNB5
Mean 15.2
Standard deviation 0.29
Values 15 15
[48]
THLE GNB5
Mean 18.5
Standard deviation 0.68
Values 18 19
[49]
liver GNB5
Mean 12.6
Standard deviation 4.4
Values 13 12 18 7.3
[50]
ref_hepatocyte GNG11
Mean 1.51
Standard deviation 1.6
Values 0 0 1.3 3.2 3
[51]
HepG2 GNG11
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[52]
HepG2.C3A GNG11
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[53]
HuH.7 GNG11
Mean 0.0158
Standard deviation 0.022
Values 0.041 0.0064 0
[54]
SNU475 GNG11
Mean 13.3
Standard deviation 2
Values 12 15
[55]
THLE GNG11
Mean 37.1
Standard deviation 6.4
Values 33 42
[56]
liver GNG11
Mean 10.1
Standard deviation 8.8
Values 16 3.1 19 2
[57]
ref_hepatocyte GNG7
Mean 0.972
Standard deviation 0.89
Values 2.2 0.22 0.098 0.76 1.6
[58]
HepG2 GNG7
Mean 6.31
Standard deviation 1.2
Values 7.2 5.5
[59]
HepG2.C3A GNG7
Mean 4.41
Standard deviation 1.7
Values 5.6 3.2
[60]
HuH.7 GNG7
Mean 7.39
Standard deviation 1.1
Values 8.1 6.1 7.9
[61]
SNU475 GNG7
Mean 0.379
Standard deviation 0.19
Values 0.51 0.24
[62]
THLE GNG7
Mean 0.654
Standard deviation 0.35
Values 0.9 0.41
[63]
liver GNG7
Mean 1.4
Standard deviation 0.99
Values 2.8 0.53 1.3 1
[64]
ref_hepatocyte GNG4
Mean 0.665
Standard deviation 1.2
Values 2.8 0.17 0.098 0.15 0.11
[65]
HepG2 GNG4
Mean 16.3
Standard deviation 4.5
Values 19 13
[66]
HepG2.C3A GNG4
Mean 3.08
Standard deviation 0.29
Values 2.9 3.3
[67]
HuH.7 GNG4
Mean 41.2
Standard deviation 8.1
Values 48 32 43
[68]
SNU475 GNG4
Mean 2.92
Standard deviation 0.47
Values 3.3 2.6
[69]
THLE GNG4
Mean 0.755
Standard deviation 0.19
Values 0.89 0.62
[70]
liver GNG4
Mean 0.161
Standard deviation 0.098
Values 0.024 0.26 0.18 0.19
[71]
ref_hepatocyte GNB4
Mean 0.389
Standard deviation 0.25
Values 0.16 0.31 0.7 0.17 0.61
[72]
HepG2 GNB4
Mean 0.666
Standard deviation 0.063
Values 0.71 0.62
[73]
HepG2.C3A GNB4
Mean 0.835
Standard deviation 0.043
Values 0.87 0.8
[74]
HuH.7 GNB4
Mean 1.6
Standard deviation 0.14
Values 1.6 1.7 1.5
[75]
SNU475 GNB4
Mean 4.59
Standard deviation 0.038
Values 4.6 4.6
[76]
THLE GNB4
Mean 34.3
Standard deviation 7.5
Values 29 40
[77]
liver GNB4
Mean 9.42
Standard deviation 4.4
Values 4.9 15 7 11
[78]
ref_hepatocyte GNG2
Mean 0.352
Standard deviation 0.41
Values 0 0.06 0.53 0.18 0.99
[79]
HepG2 GNG2
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[80]
HepG2.C3A GNG2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[81]
HuH.7 GNG2
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 GNG2
Mean 5.62
Standard deviation 1.4
Values 4.6 6.6
[83]
THLE GNG2
Mean 4.37
Standard deviation 0.87
Values 5 3.8
[84]
liver GNG2
Mean 3.44
Standard deviation 0.91
Values 3.5 3.6 4.4 2.2
[85]
ref_hepatocyte GNGT2
Mean 0.154
Standard deviation 0.23
Values 0 0 0.06 0.16 0.54
[86]
HepG2 GNGT2
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A GNGT2
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 GNGT2
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 GNGT2
Mean 0.0673
Standard deviation 0.062
Values 0.023 0.11
[90]
THLE GNGT2
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[91]
liver GNGT2
Mean 0.235
Standard deviation 0.19
Values 0.35 0.086 0.44 0.066
[92]
ref_hepatocyte GNG3
Mean 0.127
Standard deviation 0.2
Values 0 0 0 0.46 0.18
[93]
HepG2 GNG3
Mean 0.155
Standard deviation 0.032
Values 0.18 0.13
[94]
HepG2.C3A GNG3
Mean 0.493
Standard deviation 0.33
Values 0.73 0.26
[95]
HuH.7 GNG3
Mean 0.101
Standard deviation 0.06
Values 0.033 0.15 0.12
[96]
SNU475 GNG3
Mean 0.144
Standard deviation 0.053
Values 0.18 0.11
[97]
THLE GNG3
Mean 0.13
Standard deviation 0.018
Values 0.14 0.12
[98]
liver GNG3
Mean 0.17
Standard deviation 0.089
Values 0.047 0.26 0.21 0.17
[99]
ref_hepatocyte GNB3
Mean 0.0571
Standard deviation 0.11
Values 0.24 0 0 0 0.041
[100]
HepG2 GNB3
Mean 0.379
Standard deviation 0.11
Values 0.3 0.45
[101]
HepG2.C3A GNB3
Mean 1.61
Standard deviation 0.27
Values 1.4 1.8
[102]
HuH.7 GNB3
Mean 0.95
Standard deviation 0.47
Values 0.98 0.47 1.4
[103]
SNU475 GNB3
Mean 0.211
Standard deviation 0.003
Values 0.21 0.21
[104]
THLE GNB3
Mean 1.55
Standard deviation 0.56
Values 1.9 1.1
[105]
liver GNB3
Mean 0.0253
Standard deviation 0.019
Values 0.047 0.029 0.026 0
[106]
ref_hepatocyte PTGIR
Mean 0.0447
Standard deviation 0.068
Values 0 0 0 0.069 0.15
[107]
HepG2 PTGIR
Mean 0.0494
Standard deviation 0.027
Values 0.069 0.03
[108]
HepG2.C3A PTGIR
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[109]
HuH.7 PTGIR
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 PTGIR
Mean 0.0558
Standard deviation 0.079
Values 0 0.11
[111]
THLE PTGIR
Mean 1.29
Standard deviation 0.026
Values 1.3 1.3
[112]
liver PTGIR
Mean 1.83
Standard deviation 0.93
Values 2.2 1.2 3 0.95
[113]
ref_hepatocyte GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 GNGT1
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A GNGT1
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 GNGT1
Mean 0.0409
Standard deviation 0.035
Values 0.0082 0.077 0.037
[117]
SNU475 GNGT1
Mean 0.0679
Standard deviation 0.0043
Values 0.065 0.071
[118]
THLE GNGT1
Mean 0
Standard deviation 0
Values 0 0
[119]
liver GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0
[120]
ref_hepatocyte GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 GNG13
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A GNG13
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 GNG13
Mean 0.0152
Standard deviation 0.017
Values 0.033 0.013 0
[124]
SNU475 GNG13
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[125]
THLE GNG13
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[126]
liver GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0
[127]
ref_hepatocyte GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 GNG8
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A GNG8
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 GNG8
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 GNG8
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[132]
THLE GNG8
Mean 0
Standard deviation 0
Values 0 0
[133]
liver GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0