REACTOME_PROLACTIN_RECEPTOR_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SKP1 S-phase kinase-associated protein 1 [1] -0.28[2] -0.32[3] -1.09[4] -0.12[5] -0.18[6] -0.83[7]
2 RBX1 E3 ubiquitin-protein ligase RBX1 [8] -1.36[9] -1.36[10] -1.37[11] -2.32[12] -2.18[13] -2.24[14]
3 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [15] 1.14[16] 1.14[17] 1.20[18] 1.27[19] 1.62[20] 1.12[21]
4 CUL1 Cullin-1 [22] 0.31[23] 0.56[24] 0.22[25] 0.96[26] 0.34[27] 0.61[28]
5 GHR Growth hormone receptor [29] -7.05[30] -8.59[31] -2.59[32] -7.70[33] -2.08[34] 1.50[35]
6 STAT5B Signal transducer and activator of transcription 5B [36] 2.05[37] 1.25[38] 2.06[39] 1.93[40] 0.79[41] 1.49[42]
7 SH2B1 SH2B adapter protein 1 [43] 1.84[44] 2.13[45] 1.90[46] 0.70[47] 1.11[48] -0.05[49]
8 STAT5A Signal transducer and activator of transcription 5A [50] -1.25[51] -0.51[52] -1.33[53] -0.46[54] 0.01[55] 0.10[56]
9 BTRC F-box/WD repeat-containing protein 1A [57] 2.11[58] 2.47[59] 2.19[60] 1.14[61] 1.40[62] 1.21[63]
10 JAK2 Tyrosine-protein kinase JAK2 [64] 0.92[65] 0.49[66] 0.15[67] 1.15[68] 1.46[69] 2.57[70]
11 PRLR Prolactin receptor [71] 1.54[72] 1.29[73] 5.24[74] -4.63[75] -3.77[76] 3.77[77]
12 CSH1 Chorionic somatomammotropin hormone 1 [78] [79] [80] [81] [82] [83] [84]
13 GH1 Somatotropin [85] [86] [87] [88] [89] [90] [91]
14 PRL Prolactin [92] [93] [94] [95] [96] [97] [98]
15 GH2 Growth hormone variant [99] [100] [101] [102] [103] [104] [105]
[1]
ref_hepatocyte SKP1
Mean 80.8
Standard deviation 44
Values 1.5e+02 92 24 71 71
[2]
HepG2 SKP1
Mean 90.4
Standard deviation 11
Values 83 98
[3]
HepG2.C3A SKP1
Mean 106
Standard deviation 20
Values 91 1.2e+02
[4]
HuH.7 SKP1
Mean 55.5
Standard deviation 13
Values 57 42 67
[5]
SNU475 SKP1
Mean 105
Standard deviation 22
Values 1.2e+02 89
[6]
THLE SKP1
Mean 137
Standard deviation 18
Values 1.2e+02 1.5e+02
[7]
liver SKP1
Mean 71
Standard deviation 55
Values 1.1e+02 27 1.3e+02 20
[8]
ref_hepatocyte RBX1
Mean 54.3
Standard deviation 41
Values 88 1.1e+02 7.4 33 36
[9]
HepG2 RBX1
Mean 28.8
Standard deviation 5.7
Values 25 33
[10]
HepG2.C3A RBX1
Mean 34.6
Standard deviation 13
Values 26 44
[11]
HuH.7 RBX1
Mean 30.6
Standard deviation 15
Values 29 17 46
[12]
SNU475 RBX1
Mean 15.3
Standard deviation 1.3
Values 16 14
[13]
THLE RBX1
Mean 23
Standard deviation 3.5
Values 21 25
[14]
liver RBX1
Mean 18
Standard deviation 18
Values 36 2.5 32 1.8
[15]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[16]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[17]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[18]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[19]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[20]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[21]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[22]
ref_hepatocyte CUL1
Mean 14.3
Standard deviation 4.3
Values 13 22 12 14 11
[23]
HepG2 CUL1
Mean 24.2
Standard deviation 10
Values 17 31
[24]
HepG2.C3A CUL1
Mean 34.5
Standard deviation 8.6
Values 28 41
[25]
HuH.7 CUL1
Mean 24.2
Standard deviation 1.9
Values 26 22 25
[26]
SNU475 CUL1
Mean 39.3
Standard deviation 2.3
Values 41 38
[27]
THLE CUL1
Mean 34.6
Standard deviation 5.4
Values 31 38
[28]
liver CUL1
Mean 34
Standard deviation 1.6
Values 32 35 34 36
[29]
ref_hepatocyte GHR
Mean 11.8
Standard deviation 18
Values 0.44 2.3 1.4 11 44
[30]
HepG2 GHR
Mean 0.121
Standard deviation 0.032
Values 0.14 0.099
[31]
HepG2.C3A GHR
Mean 0.0501
Standard deviation 0.025
Values 0.068 0.032
[32]
HuH.7 GHR
Mean 2.85
Standard deviation 1.7
Values 1.9 4.8 1.8
[33]
SNU475 GHR
Mean 0.0798
Standard deviation 0.0053
Values 0.083 0.076
[34]
THLE GHR
Mean 5.34
Standard deviation 2.3
Values 7 3.7
[35]
liver GHR
Mean 52.3
Standard deviation 30
Values 53 41 22 94
[36]
ref_hepatocyte STAT5B
Mean 3.99
Standard deviation 1.3
Values 4.1 3.3 2.3 4.6 5.6
[37]
HepG2 STAT5B
Mean 22.6
Standard deviation 6.3
Values 27 18
[38]
HepG2.C3A STAT5B
Mean 15.5
Standard deviation 4
Values 18 13
[39]
HuH.7 STAT5B
Mean 24.2
Standard deviation 2.2
Values 25 22 26
[40]
SNU475 STAT5B
Mean 21.5
Standard deviation 4
Values 24 19
[41]
THLE STAT5B
Mean 13.3
Standard deviation 0.2
Values 13 13
[42]
liver STAT5B
Mean 17.5
Standard deviation 4.7
Values 13 21 14 22
[43]
ref_hepatocyte SH2B1
Mean 3.45
Standard deviation 1.7
Values 2.4 1.2 5.6 4.8 3.2
[44]
HepG2 SH2B1
Mean 16.9
Standard deviation 1.7
Values 16 18
[45]
HepG2.C3A SH2B1
Mean 24.6
Standard deviation 4.7
Values 28 21
[46]
HuH.7 SH2B1
Mean 18.8
Standard deviation 3
Values 18 16 22
[47]
SNU475 SH2B1
Mean 7.91
Standard deviation 1.9
Values 9.2 6.6
[48]
THLE SH2B1
Mean 14.3
Standard deviation 0.094
Values 14 14
[49]
liver SH2B1
Mean 5.21
Standard deviation 0.68
Values 5.5 5.1 4.3 5.9
[50]
ref_hepatocyte STAT5A
Mean 2.36
Standard deviation 1.6
Values 1.8 2.7 5 1.5 0.95
[51]
HepG2 STAT5A
Mean 1.35
Standard deviation 0.098
Values 1.4 1.3
[52]
HepG2.C3A STAT5A
Mean 2.72
Standard deviation 0.23
Values 2.6 2.9
[53]
HuH.7 STAT5A
Mean 1.37
Standard deviation 0.38
Values 1.1 1.8 1.2
[54]
SNU475 STAT5A
Mean 2.42
Standard deviation 0.13
Values 2.5 2.3
[55]
THLE STAT5A
Mean 4.58
Standard deviation 0.3
Values 4.8 4.4
[56]
liver STAT5A
Mean 3.96
Standard deviation 1.5
Values 3 3.5 3.3 6.2
[57]
ref_hepatocyte BTRC
Mean 2.1
Standard deviation 0.84
Values 3 2.5 2.6 1.4 1
[58]
HepG2 BTRC
Mean 12.3
Standard deviation 3.7
Values 9.7 15
[59]
HepG2.C3A BTRC
Mean 19
Standard deviation 2
Values 20 18
[60]
HuH.7 BTRC
Mean 13.9
Standard deviation 1.8
Values 14 16 12
[61]
SNU475 BTRC
Mean 6.5
Standard deviation 0.013
Values 6.5 6.5
[62]
THLE BTRC
Mean 10.6
Standard deviation 0.85
Values 10 11
[63]
liver BTRC
Mean 7.57
Standard deviation 0.65
Values 8.2 8 7.2 6.8
[64]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[65]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[66]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[67]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[68]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[69]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[70]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[71]
ref_hepatocyte PRLR
Mean 0.722
Standard deviation 0.48
Values 0.8 0.085 1.4 0.56 0.74
[72]
HepG2 PRLR
Mean 2.87
Standard deviation 1.7
Values 1.6 4.1
[73]
HepG2.C3A PRLR
Mean 2.88
Standard deviation 0.75
Values 3.4 2.3
[74]
HuH.7 PRLR
Mean 39.8
Standard deviation 25
Values 35 67 17
[75]
SNU475 PRLR
Mean 0.0411
Standard deviation 0.00084
Values 0.042 0.041
[76]
THLE PRLR
Mean 0.101
Standard deviation 0.016
Values 0.11 0.09
[77]
liver PRLR
Mean 15.4
Standard deviation 9.7
Values 9.3 27 6 19
[78]
ref_hepatocyte CSH1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 CSH1
Missing
[80]
HepG2.C3A CSH1
Missing
[81]
HuH.7 CSH1
Missing
[82]
SNU475 CSH1
Missing
[83]
THLE CSH1
Missing
[84]
liver CSH1
Missing
[85]
ref_hepatocyte GH1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 GH1
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A GH1
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 GH1
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 GH1
Mean 0.0101
Standard deviation 0.014
Values 0 0.02
[90]
THLE GH1
Mean 0
Standard deviation 0
Values 0 0
[91]
liver GH1
Mean 0
Standard deviation 0
Values 0 0 0 0
[92]
ref_hepatocyte PRL
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 PRL
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A PRL
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 PRL
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 PRL
Mean 1.78
Standard deviation 0.62
Values 2.2 1.3
[97]
THLE PRL
Mean 0.0488
Standard deviation 0.031
Values 0.071 0.027
[98]
liver PRL
Mean 0
Standard deviation 0
Values 0 0 0 0
[99]
ref_hepatocyte GH2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 GH2
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A GH2
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 GH2
Mean 0.00856
Standard deviation 0.015
Values 0 0.026 0
[103]
SNU475 GH2
Mean 0
Standard deviation 0
Values 0 0
[104]
THLE GH2
Mean 0
Standard deviation 0
Values 0 0
[105]
liver GH2
Mean 0
Standard deviation 0
Values 0 0 0 0