REACTOME_PROGRAMMED_CELL_DEATH | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.60[2] | -1.77[3] | -1.58[4] | -2.29[5] | -1.65[6] | -0.95[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -1.16[16] | -1.02[17] | -1.22[18] | -1.44[19] | -1.27[20] | -0.50[21] |
4 | HSP90AA1 | Heat shock protein HSP 90-alpha | [22] | -0.05[23] | 0.96[24] | 0.22[25] | 0.58[26] | 0.45[27] | -0.33[28] |
5 | YWHAE | 14-3-3 protein epsilon | [29] | -0.64[30] | -0.50[31] | -0.11[32] | -0.37[33] | -0.15[34] | -0.63[35] |
6 | PSME1 | Proteasome activator complex subunit 1 | [36] | -0.93[37] | -2.61[38] | -2.19[39] | -2.16[40] | -2.49[41] | -1.45[42] |
7 | YWHAZ | 14-3-3 protein zeta/delta | [43] | 0.02[44] | -0.10[45] | 0.26[46] | 1.39[47] | 0.16[48] | -0.72[49] |
8 | CD14 | Monocyte differentiation antigen CD14 | [50] | -7.74[51] | -7.78[52] | -4.93[53] | -4.32[54] | -5.32[55] | 0.42[56] |
9 | DYNLL1 | Dynein light chain 1, cytoplasmic | [57] | -0.79[58] | -0.72[59] | -0.90[60] | -1.13[61] | -1.22[62] | -1.17[63] |
10 | PSME2 | Proteasome activator complex subunit 2 | [64] | -0.75[65] | -2.23[66] | -2.28[67] | -1.94[68] | -2.03[69] | -1.07[70] |
11 | PSMA7 | Proteasome subunit alpha type-7 | [71] | 0.21[72] | 0.24[73] | -1.03[74] | -0.32[75] | -0.55[76] | -0.05[77] |
12 | PSMB1 | Proteasome subunit beta type-1 | [78] | -0.25[79] | -0.21[80] | -1.23[81] | -1.56[82] | -0.59[83] | -0.21[84] |
13 | C1QBP | Complement component 1 Q subcomponent-binding protein, mitochondrial | -0.45[85] | -0.62[86] | -0.68[87] | -1.53[88] | -1.41[89] | -0.91[90] | |
14 | PSMB3 | Proteasome subunit beta type-3 | [91] | -0.73[92] | -1.59[93] | -0.50[94] | -1.58[95] | -1.50[96] | -0.51[97] |
15 | PSMB4 | Proteasome subunit beta type-4 | [98] | -0.48[99] | -0.39[100] | -0.20[101] | -0.15[102] | 0.04[103] | -0.84[104] |
16 | PSMB7 | Proteasome subunit beta type-7 | [105] | -1.43[106] | -1.49[107] | -1.30[108] | -1.93[109] | -1.28[110] | -1.28[111] |
17 | HMGB1 | High mobility group protein B1 | [112] | 0.29[113] | 1.07[114] | 0.85[115] | 0.95[116] | 0.61[117] | 0.37[118] |
18 | PSMB5 | Proteasome subunit beta type-5 | [119] | 0.97[120] | -0.53[121] | -0.55[122] | -1.20[123] | -0.72[124] | -0.80[125] |
19 | PSMA6 | Proteasome subunit alpha type-6 | [126] | 1.10[127] | -0.25[128] | -0.26[129] | -0.68[130] | -0.46[131] | -0.72[132] |
20 | LMNA | Prelamin-A/C | [133] | 0.46[134] | -0.06[135] | -1.40[136] | 1.01[137] | 0.42[138] | -0.04[139] |
21 | PSMA4 | Proteasome subunit alpha type-4 | [140] | -0.83[141] | -0.24[142] | -0.38[143] | -0.37[144] | -0.34[145] | -0.80[146] |
22 | PSMC3 | 26S proteasome regulatory subunit 6A | [147] | -0.86[148] | -1.00[149] | -0.32[150] | -1.57[151] | -1.17[152] | -0.33[153] |
23 | PSMA3 | Proteasome subunit alpha type-3 | [154] | -1.45[155] | -0.52[156] | -1.13[157] | -0.83[158] | -1.07[159] | -0.55[160] |
24 | BCAP31 | B-cell receptor-associated protein 31 | [161] | -0.33[162] | -0.28[163] | -1.08[164] | -0.49[165] | -0.43[166] | -0.35[167] |
25 | PSMB6 | Proteasome subunit beta type-6 | [168] | -0.90[169] | -0.82[170] | -0.62[171] | -1.37[172] | -1.43[173] | -0.39[174] |
26 | CDC37 | Hsp90 co-chaperone Cdc37 | [175] | -0.16[176] | -0.78[177] | -0.37[178] | -1.32[179] | -0.56[180] | -1.05[181] |
27 | PSMA2 | Proteasome subunit alpha type-2 | [182] | -0.99[183] | -0.10[184] | 0.30[185] | -0.88[186] | -0.30[187] | -0.17[188] |
28 | CHMP2A | Charged multivesicular body protein 2a | [189] | -2.51[190] | -2.95[191] | -3.10[192] | -1.74[193] | -2.31[194] | -1.21[195] |
29 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [196] | -0.47[197] | -0.52[198] | -0.26[199] | -0.17[200] | -0.50[201] | -0.49[202] |
30 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [203] | -0.55[204] | -0.25[205] | -0.33[206] | -1.26[207] | -0.58[208] | -0.67[209] |
31 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [210] | -0.39[211] | -0.21[212] | -0.01[213] | -0.99[214] | -0.02[215] | -0.64[216] |
32 | YWHAH | 14-3-3 protein eta | [217] | -0.77[218] | -1.15[219] | -1.14[220] | -0.70[221] | -0.92[222] | -1.03[223] |
33 | YWHAQ | 14-3-3 protein theta | [224] | 0.86[225] | 0.71[226] | 0.45[227] | 1.84[228] | 1.35[229] | 0.33[230] |
34 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [231] | 1.15[232] | 0.26[233] | 0.39[234] | 0.12[235] | 1.63[236] | 0.39[237] |
35 | CHMP4B | Charged multivesicular body protein 4b | [238] | -0.14[239] | -0.70[240] | -1.23[241] | -0.18[242] | -0.90[243] | -3.63[244] |
36 | SFN | 14-3-3 protein sigma | [245] | -1.77[246] | -2.09[247] | -1.66[248] | -7.34[249] | -8.09[250] | -9.17[251] |
37 | PSMC1 | 26S proteasome regulatory subunit 4 | [252] | -0.53[253] | -0.53[254] | -1.12[255] | 0.31[256] | 0.04[257] | -0.45[258] |
38 | PSMA1 | Proteasome subunit alpha type-1 | [259] | -0.35[260] | -0.02[261] | 0.10[262] | -0.12[263] | -0.40[264] | 0.04[265] |
39 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [266] | 1.27[267] | 1.22[268] | 2.29[269] | -0.04[270] | 0.96[271] | 0.27[272] |
40 | PSMC5 | 26S proteasome regulatory subunit 8 | [273] | -0.03[274] | -0.20[275] | -0.06[276] | -0.71[277] | -0.08[278] | -0.19[279] |
41 | VIM | Vimentin | [280] | -7.75[281] | -8.16[282] | -2.47[283] | 3.09[284] | 2.69[285] | -0.31[286] |
42 | FLOT1 | Flotillin-1 | [287] | -0.03[288] | 0.52[289] | -0.08[290] | 0.70[291] | 0.03[292] | -0.32[293] |
43 | GSN | Gelsolin | [294] | 1.51[295] | 1.29[296] | -1.74[297] | -0.93[298] | -1.33[299] | -0.98[300] |
44 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [301] | 0.37[302] | -0.21[303] | 0.45[304] | -0.18[305] | 0.26[306] | -0.48[307] |
45 | YWHAG | 14-3-3 protein gamma | [308] | 0.80[309] | 0.30[310] | 0.39[311] | 1.21[312] | 0.70[313] | -0.42[314] |
46 | PSMB8 | Proteasome subunit beta type-8 | [315] | -2.03[316] | -2.69[317] | -9.84[318] | -0.20[319] | -1.30[320] | -1.16[321] |
47 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [322] | -0.46[323] | 0.09[324] | 0.40[325] | -0.31[326] | -0.07[327] | -0.62[328] |
48 | PSMC4 | 26S proteasome regulatory subunit 6B | [329] | -0.03[330] | -0.06[331] | -0.07[332] | -0.68[333] | -0.36[334] | -0.14[335] |
49 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [336] | -1.18[337] | -0.77[338] | -1.80[339] | -1.31[340] | -0.29[341] | -0.73[342] |
50 | YWHAB | 14-3-3 protein beta/alpha | [343] | 1.63[344] | 1.38[345] | 0.70[346] | 1.79[347] | 1.41[348] | 0.83[349] |
51 | KPNB1 | Importin subunit beta-1 | [350] | 1.51[351] | 1.70[352] | 2.03[353] | 1.69[354] | 1.48[355] | 0.38[356] |
52 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [357] | 0.01[358] | 0.06[359] | 0.62[360] | -0.25[361] | -0.53[362] | -0.54[363] |
53 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [364] | -0.81[365] | -0.79[366] | -1.04[367] | -0.63[368] | -0.35[369] | -0.62[370] |
54 | HMGB2 | High mobility group protein B2 | [371] | 0.24[372] | 1.45[373] | 2.29[374] | -1.15[375] | 0.74[376] | -2.39[377] |
55 | AKT1 | RAC-alpha serine/threonine-protein kinase | [378] | 0.68[379] | 0.48[380] | -0.56[381] | 0.44[382] | 0.64[383] | 0.68[384] |
56 | CTNNB1 | Catenin beta-1 | [385] | 2.21[386] | 1.74[387] | 2.67[388] | 1.24[389] | 1.66[390] | 2.04[391] |
57 | STUB1 | E3 ubiquitin-protein ligase CHIP | [392] | -1.39[393] | -1.33[394] | -1.95[395] | -2.17[396] | -1.66[397] | -1.32[398] |
58 | PSMC6 | 26S proteasome regulatory subunit 10B | [399] | -0.51[400] | 1.00[401] | -0.12[402] | -0.27[403] | -0.13[404] | 0.03[405] |
59 | DYNLL2 | Dynein light chain 2, cytoplasmic | [406] | -0.37[407] | -0.89[408] | -0.63[409] | -2.38[410] | -0.62[411] | -2.01[412] |
60 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [413] | 0.37[414] | -0.08[415] | 0.57[416] | 0.13[417] | 0.50[418] | 0.86[419] |
61 | CASP4 | Caspase-4 | [420] | -0.70[421] | -1.03[422] | -0.39[423] | -0.86[424] | -0.70[425] | -1.35[426] |
62 | SDCBP | Syntenin-1 | [427] | -0.42[428] | -0.70[429] | -1.30[430] | 1.52[431] | 1.33[432] | 0.91[433] |
63 | PSMC2 | 26S proteasome regulatory subunit 7 | [434] | 0.13[435] | 0.46[436] | 0.30[437] | 0.53[438] | 0.57[439] | 0.91[440] |
64 | STAT3 | Signal transducer and activator of transcription 3 | [441] | 1.15[442] | -0.32[443] | 0.46[444] | 0.73[445] | 0.19[446] | 3.33[447] |
65 | CHMP4A | Charged multivesicular body protein 4a | [448] | 0.44[449] | -1.58[450] | -1.19[451] | -1.47[452] | -1.83[453] | -1.26[454] |
66 | FLOT2 | Flotillin-2 | [455] | 0.08[456] | 0.04[457] | 0.46[458] | 0.14[459] | 0.02[460] | 1.48[461] |
67 | PSME3 | Proteasome activator complex subunit 3 | [462] | 1.36[463] | 1.01[464] | 0.75[465] | 0.55[466] | 1.03[467] | 0.47[468] |
68 | BCL2L1 | Bcl-2-like protein 1 | [469] | 2.73[470] | 2.16[471] | 3.15[472] | -0.13[473] | 0.44[474] | 0.11[475] |
69 | BAX | Apoptosis regulator BAX | [476] | 0.92[477] | 0.17[478] | -0.26[479] | -1.11[480] | -0.55[481] | -3.03[482] |
70 | DBNL | Drebrin-like protein | [483] | 0.14[484] | -0.40[485] | -0.69[486] | 0.52[487] | 0.51[488] | 0.25[489] |
71 | GSDMD | Gasdermin-D | [490] | -1.33[491] | -0.47[492] | -1.10[493] | -0.78[494] | -1.66[495] | 0.27[496] |
72 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [497] | 1.12[498] | 1.37[499] | 1.31[500] | 1.36[501] | 1.58[502] | 1.66[503] |
73 | PSMB10 | Proteasome subunit beta type-10 | [504] | -1.61[505] | -1.08[506] | -2.91[507] | -0.85[508] | -1.80[509] | -0.49[510] |
74 | MAGED1 | Melanoma-associated antigen D1 | [511] | 2.00[512] | 1.80[513] | -7.16[514] | 2.36[515] | 1.04[516] | 1.13[517] |
75 | PSMA5 | Proteasome subunit alpha type-5 | [518] | 1.44[519] | 1.80[520] | 1.43[521] | 1.41[522] | 1.18[523] | 1.50[524] |
76 | TNFSF10 | Tumor necrosis factor ligand superfamily member 10 | [525] | -3.88[526] | -2.24[527] | 0.42[528] | -1.98[529] | -5.05[530] | -0.46[531] |
77 | PSMF1 | Proteasome inhibitor PI31 subunit | [532] | 1.82[533] | 1.80[534] | 0.67[535] | 0.42[536] | 0.39[537] | 1.44[538] |
78 | TJP2 | Tight junction protein ZO-2 | [539] | 2.01[540] | 1.82[541] | 2.04[542] | -1.02[543] | 1.72[544] | 1.41[545] |
79 | ADD1 | Alpha-adducin | [546] | 1.68[547] | 0.83[548] | 1.57[549] | 2.49[550] | 1.28[551] | 1.53[552] |
80 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | -0.30[553] | 0.70[554] | 1.28[555] | -1.13[556] | -0.43[557] | 0.03[558] | |
81 | DAPK3 | Death-associated protein kinase 3 | [559] | -0.02[560] | -0.19[561] | -0.33[562] | -0.28[563] | 0.17[564] | -1.63[565] |
82 | BAD | Bcl2-associated agonist of cell death | [566] | -1.07[567] | -0.91[568] | -1.82[569] | -0.58[570] | 0.01[571] | -0.49[572] |
83 | PSMB2 | Proteasome subunit beta type-2 | [573] | 1.60[574] | 1.27[575] | 1.72[576] | 1.72[577] | 1.91[578] | 1.99[579] |
84 | CFLAR | CASP8 and FADD-like apoptosis regulator | [580] | 0.21[581] | 0.99[582] | 0.58[583] | -0.05[584] | 0.29[585] | 2.49[586] |
85 | DIABLO | Diablo homolog, mitochondrial | [587] | 0.45[588] | 0.74[589] | 0.47[590] | 0.16[591] | 0.10[592] | 0.20[593] |
86 | NMT1 | Glycylpeptide N-tetradecanoyltransferase 1 | [594] | 2.08[595] | 1.95[596] | 2.26[597] | 1.25[598] | 1.60[599] | 1.35[600] |
87 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | [601] | -2.52[602] | -1.46[603] | -3.82[604] | -2.63[605] | 1.32[606] | -1.15[607] |
88 | ACIN1 | Apoptotic chromatin condensation inducer in the nucleus | [608] | 2.06[609] | 1.41[610] | 1.81[611] | 1.72[612] | 1.86[613] | 0.47[614] |
89 | PSMB9 | Proteasome subunit beta type-9 | [615] | -2.40[616] | -5.09[617] | -7.34[618] | 0.97[619] | -1.09[620] | -0.91[621] |
90 | TNFRSF10 | Tumor necrosis factor receptor superfamily member 10B | [622] | 2.58[623] | 2.49[624] | 2.33[625] | 0.16[626] | 1.95[627] | 0.96[628] |
91 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [629] | -0.02[630] | 0.40[631] | -0.52[632] | -0.41[633] | 0.24[634] | 0.32[635] |
92 | CYCS | Cytochrome c | [636] | 1.93[637] | 2.16[638] | 2.27[639] | 1.82[640] | 2.41[641] | 2.25[642] |
93 | TFDP1 | Transcription factor Dp-1 | [643] | 1.26[644] | 0.63[645] | 0.73[646] | 1.09[647] | 1.85[648] | -0.21[649] |
94 | APIP | Methylthioribulose-1-phosphate dehydratase | [650] | -1.07[651] | -0.32[652] | -0.06[653] | -1.05[654] | -1.39[655] | -0.29[656] |
95 | DSP | Desmoplakin | [657] | 3.65[658] | 4.00[659] | 2.58[660] | 1.07[661] | -1.60[662] | 3.76[663] |
96 | IL18 | Interleukin-18 | [664] | -0.27[665] | -4.07[666] | 0.10[667] | -0.68[668] | -1.16[669] | -3.23[670] |
97 | PDCD6IP | Programmed cell death 6-interacting protein | [671] | 1.11[672] | 1.14[673] | 2.44[674] | 1.37[675] | 1.98[676] | 2.01[677] |
98 | PPP3R1 | Calcineurin subunit B type 1 | [678] | 0.78[679] | 1.00[680] | 0.95[681] | 1.19[682] | 1.14[683] | -0.22[684] |
99 | CASP3 | Caspase-3 | [685] | 0.73[686] | 1.44[687] | -1.07[688] | -0.41[689] | 0.77[690] | 0.12[691] |
100 | SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 | [692] | 3.34[693] | 2.71[694] | 3.42[695] | 3.24[696] | 3.56[697] | 2.87[698] |
101 | CHMP2B | Charged multivesicular body protein 2b | [699] | -0.43[700] | 0.46[701] | 1.24[702] | -0.25[703] | 0.56[704] | 0.88[705] |
102 | BID | BH3-interacting domain death agonist | [706] | 0.33[707] | 0.47[708] | 0.12[709] | 0.20[710] | -0.15[711] | 1.10[712] |
103 | CDH1 | Cadherin-1 | [713] | 1.71[714] | 2.23[715] | 2.80[716] | -2.68[717] | -6.75[718] | 2.49[719] |
104 | STK24 | Serine/threonine-protein kinase 24 | [720] | 1.73[721] | 1.69[722] | 1.31[723] | 0.67[724] | 1.85[725] | -0.01[726] |
105 | DFFA | DNA fragmentation factor subunit alpha | [727] | 0.36[728] | 0.74[729] | 0.46[730] | 0.22[731] | 0.44[732] | 0.66[733] |
106 | PAK2 | Serine/threonine-protein kinase PAK 2 | [734] | 2.04[735] | 1.82[736] | 2.16[737] | 1.24[738] | 1.97[739] | 2.29[740] |
107 | FAS | Tumor necrosis factor receptor superfamily member 6 | [741] | -1.00[742] | -0.19[743] | -8.16[744] | -1.26[745] | -0.55[746] | -0.79[747] |
108 | MAPK1 | Mitogen-activated protein kinase 1 | [748] | 2.30[749] | 2.48[750] | 2.34[751] | 2.34[752] | 2.17[753] | 2.70[754] |
109 | AKT2 | RAC-beta serine/threonine-protein kinase | [755] | 1.55[756] | 1.86[757] | 2.03[758] | 1.35[759] | 1.32[760] | 2.06[761] |
110 | CHMP3 | Charged multivesicular body protein 3 | [762] | -1.73[763] | -1.79[764] | -2.44[765] | -2.57[766] | -2.84[767] | -3.86[768] |
111 | CASP7 | Caspase-7 | [769] | 0.28[770] | -0.04[771] | 0.44[772] | -0.41[773] | -0.02[774] | 0.45[775] |
112 | BIRC2 | Baculoviral IAP repeat-containing protein 2 | [776] | 0.84[777] | 1.83[778] | 0.81[779] | 0.91[780] | 1.88[781] | 1.66[782] |
113 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [783] | 0.54[784] | 0.79[785] | 0.87[786] | 1.26[787] | 0.79[788] | 0.30[789] |
114 | CHMP6 | Charged multivesicular body protein 6 | [790] | 0.23[791] | 0.37[792] | -1.57[793] | -0.34[794] | -0.92[795] | 0.59[796] |
115 | FADD | FAS-associated death domain protein | [797] | 0.63[798] | -0.04[799] | 0.72[800] | 2.42[801] | 0.42[802] | -0.84[803] |
116 | IRF2 | Interferon regulatory factor 2 | [804] | -0.50[805] | -0.07[806] | -1.20[807] | -0.61[808] | -0.36[809] | 0.59[810] |
117 | PTK2 | Focal adhesion kinase 1 | [811] | 1.33[812] | 1.85[813] | 2.27[814] | 2.44[815] | 1.82[816] | 1.69[817] |
118 | CASP8 | Caspase-8 | [818] | 0.61[819] | 1.22[820] | 0.43[821] | 0.41[822] | -0.15[823] | -0.49[824] |
119 | DSG2 | Desmoglein-2 | [825] | 2.24[826] | 2.75[827] | 1.98[828] | 3.04[829] | 2.75[830] | 1.47[831] |
120 | CASP6 | Caspase-6 | [832] | -0.67[833] | -0.43[834] | -0.03[835] | -0.46[836] | -0.60[837] | 0.05[838] |
121 | TNFRSF10 | Tumor necrosis factor receptor superfamily member 10A | [839] | -0.85[840] | -1.28[841] | -1.22[842] | -2.53[843] | -2.60[844] | -0.78[845] |
122 | LMNB1 | Lamin-B1 | [846] | 1.58[847] | 1.65[848] | 1.74[849] | 1.80[850] | 1.63[851] | -1.27[852] |
123 | OGT | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subu | 1.81[853] | 2.71[854] | 2.78[855] | 2.02[856] | 2.16[857] | 3.28[858] | |
124 | PSME4 | Proteasome activator complex subunit 4 | [859] | 2.06[860] | 2.91[861] | 2.97[862] | 1.82[863] | 1.99[864] | 2.57[865] |
125 | OMA1 | Metalloendopeptidase OMA1, mitochondrial | [866] | -1.39[867] | -0.86[868] | -1.07[869] | -0.97[870] | -1.82[871] | 0.65[872] |
126 | MAPK8 | Mitogen-activated protein kinase 8 | [873] | -0.85[874] | 0.60[875] | -0.50[876] | -0.41[877] | -0.37[878] | 0.42[879] |
127 | OPA1 | Dynamin-like 120 kDa protein, mitochondrial | [880] | 0.68[881] | 2.12[882] | 2.10[883] | 1.34[884] | 2.11[885] | 2.80[886] |
128 | ROCK1 | Rho-associated protein kinase 1 | [887] | -0.36[888] | 1.20[889] | 2.01[890] | 1.85[891] | 1.38[892] | 2.51[893] |
129 | TJP1 | Tight junction protein ZO-1 | [894] | 1.05[895] | 1.30[896] | 1.11[897] | 2.19[898] | 1.83[899] | 2.76[900] |
130 | DNM1L | Dynamin-1-like protein | [901] | 1.14[902] | 1.99[903] | 2.06[904] | 3.19[905] | 2.37[906] | 1.83[907] |
131 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [908] | 0.95[909] | 0.44[910] | 2.06[911] | 1.65[912] | 1.94[913] | 1.75[914] |
132 | TP53BP2 | Apoptosis-stimulating of p53 protein 2 | [915] | -0.01[916] | 0.35[917] | 1.97[918] | 1.74[919] | 1.22[920] | 0.99[921] |
133 | IRF1 | Interferon regulatory factor 1 | [922] | 0.09[923] | -0.35[924] | -0.17[925] | 1.75[926] | 0.93[927] | 1.76[928] |
134 | BAK1 | Bcl-2 homologous antagonist/killer | [929] | 1.49[930] | 1.06[931] | 1.07[932] | 1.68[933] | 1.34[934] | -0.86[935] |
135 | KPNA1 | Importin subunit alpha-5 | [936] | 1.65[937] | 1.74[938] | 1.88[939] | 2.07[940] | 2.56[941] | 3.10[942] |
136 | OCLN | Occludin | [943] | 0.35[944] | 1.34[945] | 1.62[946] | -1.64[947] | -3.03[948] | 2.62[949] |
137 | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein | 0.34[950] | 0.21[951] | -0.92[952] | -0.50[953] | -0.46[954] | 0.34[955] | |
138 | AVEN | Cell death regulator Aven | [956] | -0.38[957] | -0.61[958] | -2.66[959] | -0.57[960] | -0.29[961] | -0.28[962] |
139 | PLEC | Plectin | [963] | 3.99[964] | 1.62[965] | 3.06[966] | 5.17[967] | 4.99[968] | 4.93[969] |
140 | TP53 | Cellular tumor antigen p53 | [970] | 2.23[971] | 1.83[972] | 2.63[973] | 1.78[974] | 1.63[975] | 0.89[976] |
141 | TRAF2 | TNF receptor-associated factor 2 | [977] | 0.82[978] | 0.92[979] | 0.69[980] | 0.61[981] | 0.80[982] | 0.13[983] |
142 | TICAM1 | TIR domain-containing adapter molecule 1 | [984] | -0.12[985] | -1.18[986] | -0.21[987] | -0.74[988] | 0.50[989] | 0.43[990] |
143 | APPL1 | DCC-interacting protein 13-alpha | [991] | 0.64[992] | 1.87[993] | 1.13[994] | 1.26[995] | 1.94[996] | 2.73[997] |
144 | CHMP7 | Charged multivesicular body protein 7 | [998] | 1.77[999] | 1.43[1000] | 1.94[1001] | 1.20[1002] | 1.52[1003] | 1.77[1004] |
145 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | [1005] | 0.88[1006] | 1.08[1007] | 0.80[1008] | 1.57[1009] | 1.27[1010] | 2.41[1011] |
146 | MAPK3 | Mitogen-activated protein kinase 3 | [1012] | 2.44[1013] | 2.53[1014] | 2.60[1015] | 0.91[1016] | 1.12[1017] | -0.11[1018] |
147 | BBC3 | Bcl-2-binding component 3 | [1019] | 1.33[1020] | 1.26[1021] | 0.79[1022] | -2.31[1023] | -1.37[1024] | -3.41[1025] |
148 | CHMP4C | Charged multivesicular body protein 4c | [1026] | 1.04[1027] | 1.10[1028] | -0.87[1029] | 0.10[1030] | -1.67[1031] | -0.58[1032] |
149 | PPP3CC | Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform | -0.11[1033] | 0.06[1034] | -0.30[1035] | -0.60[1036] | 0.50[1037] | 0.99[1038] | |
150 | CASP1 | Caspase-1 | [1039] | -2.44[1040] | -5.80[1041] | -4.24[1042] | 0.57[1043] | 0.91[1044] | 0.20[1045] |
151 | PRKCD | Protein kinase C delta type | [1046] | 1.69[1047] | 1.98[1048] | 1.49[1049] | -0.02[1050] | 1.33[1051] | -0.14[1052] |
152 | DAPK1 | Death-associated protein kinase 1 | [1053] | 1.67[1054] | 1.69[1055] | 2.70[1056] | 1.19[1057] | 1.53[1058] | 3.63[1059] |
153 | GAS2 | Growth arrest-specific protein 2 | [1060] | -0.24[1061] | 2.73[1062] | 2.46[1063] | -4.91[1064] | -5.20[1065] | 3.19[1066] |
154 | IL1B | Interleukin-1 beta | [1067] | -8.10[1068] | -7.93[1069] | -3.57[1070] | -3.10[1071] | 2.67[1072] | -4.27[1073] |
155 | LY96 | Lymphocyte antigen 96 | [1074] | -2.06[1075] | -2.41[1076] | -8.79[1077] | -0.87[1078] | -4.31[1079] | -0.43[1080] |
156 | UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats | [1081] | 0.29[1082] | 2.54[1083] | 2.64[1084] | 3.36[1085] | 2.22[1086] | 2.71[1087] |
157 | BMF | Bcl-2-modifying factor | [1088] | 1.41[1089] | 1.82[1090] | 2.92[1091] | 4.12[1092] | -1.05[1093] | 0.13[1094] |
158 | XIAP | E3 ubiquitin-protein ligase XIAP | [1095] | 2.11[1096] | 2.74[1097] | 3.23[1098] | 3.08[1099] | 2.69[1100] | 3.61[1101] |
159 | PELI1 | E3 ubiquitin-protein ligase pellino homolog 1 | [1102] | 0.74[1103] | 1.69[1104] | 2.24[1105] | 0.23[1106] | 0.51[1107] | 2.33[1108] |
160 | CASP9 | Caspase-9 | [1109] | 0.75[1110] | 1.75[1111] | 0.90[1112] | 0.73[1113] | 0.23[1114] | 0.39[1115] |
161 | E2F1 | Transcription factor E2F1 | [1116] | 2.54[1117] | 2.43[1118] | 2.60[1119] | 2.35[1120] | 2.98[1121] | -2.69[1122] |
162 | CARD8 | Caspase recruitment domain-containing protein 8 | [1123] | 0.40[1124] | 1.24[1125] | 2.41[1126] | 1.20[1127] | 1.40[1128] | 2.35[1129] |
163 | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1 | [1130] | 0.64[1131] | -2.68[1132] | 0.90[1133] | 2.77[1134] | 2.18[1135] | -3.37[1136] |
164 | MLKL | Mixed lineage kinase domain-like protein | [1137] | 0.44[1138] | 0.36[1139] | -1.27[1140] | -0.03[1141] | 0.55[1142] | 0.71[1143] |
165 | TFDP2 | Transcription factor Dp-2 | [1144] | 2.50[1145] | 3.23[1146] | 3.28[1147] | 2.87[1148] | 3.29[1149] | 3.28[1150] |
166 | ARHGAP1 | Rho GTPase-activating protein 10 | [1151] | -2.07[1152] | -4.66[1153] | -0.78[1154] | 0.72[1155] | 2.19[1156] | 1.17[1157] |
167 | PPP1R13B | Apoptosis-stimulating of p53 protein 1 | [1158] | 2.14[1159] | 1.47[1160] | 0.59[1161] | 1.44[1162] | 1.48[1163] | 1.92[1164] |
168 | BCL2L11 | Bcl-2-like protein 11 | [1165] | 2.10[1166] | 2.14[1167] | 2.51[1168] | 2.35[1169] | 1.51[1170] | 2.91[1171] |
169 | SATB1 | DNA-binding protein SATB1 | [1172] | -4.33[1173] | -5.52[1174] | 3.31[1175] | 1.18[1176] | -2.05[1177] | 3.32[1178] |
170 | APAF1 | Apoptotic protease-activating factor 1 | [1179] | 2.25[1180] | 2.71[1181] | 3.00[1182] | 3.11[1183] | 2.40[1184] | 2.42[1185] |
171 | CLSPN | Claspin | [1186] | 1.95[1187] | 2.42[1188] | 2.74[1189] | 3.23[1190] | 3.81[1191] | -0.21[1192] |
172 | APC | Adenomatous polyposis coli protein | [1193] | 1.17[1194] | 2.87[1195] | 2.75[1196] | 2.71[1197] | 3.53[1198] | 4.66[1199] |
173 | DFFB | DNA fragmentation factor subunit beta | [1200] | 1.48[1201] | 2.44[1202] | 1.84[1203] | 1.26[1204] | 1.11[1205] | 1.56[1206] |
174 | TLR4 | Toll-like receptor 4 | [1207] | 0.87[1208] | -4.25[1209] | -5.10[1210] | -4.61[1211] | 5.99[1212] | 5.39[1213] |
175 | TICAM2 | TIR domain-containing adapter molecule 2 | [1214] | -7.28[1215] | [1216] | -6.63[1217] | -1.01[1218] | -0.48[1219] | -1.05[1220] |
176 | MAPT | Microtubule-associated protein tau | [1221] | 3.12[1222] | 3.10[1223] | 2.43[1224] | 1.82[1225] | -1.05[1226] | 1.26[1227] |
177 | AKT3 | RAC-gamma serine/threonine-protein kinase | [1228] | -1.25[1229] | -3.77[1230] | -3.05[1231] | 6.33[1232] | 5.47[1233] | 4.54[1234] |
178 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | [1235] | 4.68[1236] | 2.48[1237] | 5.92[1238] | 5.70[1239] | 7.66[1240] | -1.23[1241] |
179 | GZMB | Granzyme B | [1242] | -4.02[1243] | [1244] | [1245] | [1246] | [1247] | 0.22[1248] |
180 | DAPK2 | Death-associated protein kinase 2 | [1249] | -0.30[1250] | -1.61[1251] | 3.10[1252] | 1.75[1253] | 0.62[1254] | 1.96[1255] |
181 | RIPK3 | Receptor-interacting serine/threonine-protein kinase 3 | [1256] | -6.05[1257] | [1258] | -4.66[1259] | [1260] | -4.71[1261] | 1.48[1262] |
182 | DSG1 | Desmoglein-1 | [1263] | -4.27[1264] | -1.25[1265] | 0.33[1266] | -5.07[1267] | [1268] | 3.39[1269] |
183 | TP73 | Tumor protein p73 | [1270] | 1.32[1271] | 3.91[1272] | 2.87[1273] | 1.17[1274] | 2.48[1275] | 1.58[1276] |
184 | UNC5B | Netrin receptor UNC5B | [1277] | 2.97[1278] | -0.35[1279] | 2.22[1280] | 3.30[1281] | 7.78[1282] | 4.02[1283] |
185 | BCL2 | Apoptosis regulator Bcl-2 | [1284] | -2.26[1285] | 3.18[1286] | -4.19[1287] | 2.26[1288] | 2.16[1289] | 4.16[1290] |
186 | DSG3 | Desmoglein-3 | [1291] | 1.61[1292] | 2.61[1293] | 5.47[1294] | 1.83[1295] | 1.58[1296] | 3.90[1297] |
187 | TP63 | Tumor protein 63 | [1298] | [1299] | [1300] | -1.40[1301] | -0.88[1302] | -4.28[1303] | -0.55[1304] |
188 | FASLG | Tumor necrosis factor ligand superfamily member 6 | [1305] | -3.22[1306] | -1.31[1307] | -5.25[1308] | [1309] | [1310] | 1.51[1311] |
189 | PRKCQ | Protein kinase C theta type | [1312] | 1.50[1313] | -2.03[1314] | [1315] | 2.62[1316] | 4.30[1317] | 3.02[1318] |
190 | IL1A | Interleukin-1 alpha | [1319] | 0.17[1320] | -0.20[1321] | -1.34[1322] | -0.15[1323] | 6.78[1324] | -0.65[1325] |
191 | ELANE | Neutrophil elastase | [1326] | [1327] | [1328] | -1.78[1329] | -1.17[1330] | -3.57[1331] | 2.98[1332] |
192 | CASP5 | Caspase-5 | [1333] | -3.32[1334] | [1335] | 1.30[1336] | -3.15[1337] | -1.90[1338] | 1.44[1339] |
193 | UNC5A | Netrin receptor UNC5A | [1340] | 1.93[1341] | [1342] | 2.09[1343] | [1344] | 1.52[1345] | 5.28[1346] |
194 | SEM1 | Putative protein SEM1, isoform 2 | [1347] | [1348] | [1349] | [1350] | [1351] | [1352] | [1353] |
195 | H1-0 | [1354] | [1355] | [1356] | [1357] | [1358] | [1359] | [1360] | |
196 | H1-1 | [1361] | [1362] | [1363] | [1364] | [1365] | [1366] | [1367] | |
197 | PKP1 | Plakophilin-1 | [1368] | [1369] | [1370] | [1371] | [1372] | [1373] | [1374] |
198 | DCC | Netrin receptor DCC | [1375] | [1376] | [1377] | [1378] | [1379] | [1380] | [1381] |
199 | PSMA8 | Proteasome subunit alpha type-7-like | [1382] | [1383] | [1384] | [1385] | [1386] | [1387] | [1388] |
200 | BMX | Cytoplasmic tyrosine-protein kinase BMX | [1389] | [1390] | [1391] | [1392] | [1393] | [1394] | [1395] |
201 | SEPTIN4 | [1396] | [1397] | [1398] | [1399] | [1400] | [1401] | [1402] | |
202 | H1-5 | [1403] | [1404] | [1405] | [1406] | [1407] | [1408] | [1409] | |
203 | PSMB11 | Proteasome subunit beta type-11 | [1410] | [1411] | [1412] | [1413] | [1414] | [1415] | [1416] |
204 | STK26 | Serine/threonine-protein kinase 26 | [1417] | [1418] | [1419] | [1420] | [1421] | [1422] | [1423] |
205 | H1-2 | [1424] | [1425] | [1426] | [1427] | [1428] | [1429] | [1430] | |
206 | H1-4 | [1431] | [1432] | [1433] | [1434] | [1435] | [1436] | [1437] | |
207 | GSDME | Gasdermin-E | [1438] | [1439] | [1440] | [1441] | [1442] | [1443] | [1444] |
208 | H1-3 | [1445] | [1446] | [1447] | [1448] | [1449] | [1450] | [1451] |