REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TMED2 Transmembrane emp24 domain-containing protein 2 [1] -1.14[2] -0.19[3] -1.22[4] -1.33[5] -1.46[6] -0.78[7]
2 FURIN Furin [8] 1.39[9] -2.24[10] 0.03[11] -1.53[12] -1.13[13] 0.55[14]
3 RAB6A Ras-related protein Rab-6A [15] -0.36[16] -0.36[17] -0.45[18] -0.92[19] -1.07[20] -0.79[21]
4 B4GALT1 Beta-1,4-galactosyltransferase 1 [22] -0.36[23] -0.36[24] 0.71[25] -0.31[26] 1.44[27] -0.46[28]
5 ATP2A2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [29] 1.34[30] 1.33[31] 1.73[32] 2.55[33] 1.43[34] 0.63[35]
6 SEL1L Protein sel-1 homolog 1 [36] 0.08[37] 0.64[38] 0.67[39] 0.70[40] 0.34[41] 1.72[42]
7 RFNG Beta-1,3-N-acetylglucosaminyltransferase radical fringe [43] 0.00[44] 0.48[45] -1.63[46] -2.08[47] -2.31[48] -2.26[49]
8 ST3GAL6 Type 2 lactosamine alpha-2,3-sialyltransferase [50] -2.57[51] -0.69[52] 0.35[53] -6.96[54] -1.87[55] -0.47[56]
9 ST3GAL4 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 -1.01[57] -1.37[58] -3.24[59] 0.36[60] -0.32[61] -2.21[62]
10 NOTCH2 Neurogenic locus notch homolog protein 2 [63] -0.10[64] -5.71[65] 1.87[66] 2.77[67] 3.51[68] 2.22[69]
11 ST3GAL3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase -0.34[70] 0.01[71] 0.26[72] -0.46[73] 0.01[74] -1.44[75]
12 NOTCH1 Neurogenic locus notch homolog protein 1 [76] 1.67[77] 0.63[78] 2.07[79] 2.32[80] 2.62[81] 3.53[82]
13 MFNG Beta-1,3-N-acetylglucosaminyltransferase manic fringe [83] -0.66[84] 5.48[85] 0.11[86] -3.29[87] -5.10[88] 1.38[89]
14 LFNG Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe [90] 2.21[91] -1.52[92] 1.04[93] -1.21[94] 0.51[95] -0.79[96]
15 ATP2A3 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 [97] 1.89[98] -2.49[99] 1.45[100] 0.85[101] 0.41[102] 1.56[103]
16 NOTCH3 Neurogenic locus notch homolog protein 3 [104] 3.83[105] -0.41[106] 5.67[107] 5.99[108] 3.77[109] 2.97[110]
17 NOTCH4 Neurogenic locus notch homolog protein 4 [111] 0.33[112] 1.02[113] -1.51[114] -2.27[115] 0.28[116] 5.11[117]
18 ATP2A1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [118] 4.32[119] 6.38[120] 2.92[121] 2.02[122] 2.39[123] 0.49[124]
[1]
ref_hepatocyte TMED2
Mean 125
Standard deviation 37
Values 1.5e+02 1.6e+02 71 1.3e+02 1.1e+02
[2]
HepG2 TMED2
Mean 147
Standard deviation 20
Values 1.3e+02 1.6e+02
[3]
HepG2.C3A TMED2
Mean 233
Standard deviation 15
Values 2.2e+02 2.4e+02
[4]
HuH.7 TMED2
Mean 101
Standard deviation 12
Values 91 1.1e+02 98
[5]
SNU475 TMED2
Mean 110
Standard deviation 17
Values 1.2e+02 98
[6]
THLE TMED2
Mean 117
Standard deviation 20
Values 1e+02 1.3e+02
[7]
liver TMED2
Mean 222
Standard deviation 83
Values 1.8e+02 1.8e+02 3.5e+02 1.8e+02
[8]
ref_hepatocyte FURIN
Mean 36.4
Standard deviation 35
Values 1.6 11 25 83 62
[9]
HepG2 FURIN
Mean 249
Standard deviation 93
Values 3.1e+02 1.8e+02
[10]
HepG2.C3A FURIN
Mean 16.4
Standard deviation 4.8
Values 13 20
[11]
HuH.7 FURIN
Mean 70.6
Standard deviation 9.9
Values 82 63 67
[12]
SNU475 FURIN
Mean 27.8
Standard deviation 0.065
Values 28 28
[13]
THLE FURIN
Mean 42.8
Standard deviation 10
Values 35 50
[14]
liver FURIN
Mean 163
Standard deviation 30
Values 2e+02 1.5e+02 1.3e+02 1.7e+02
[15]
ref_hepatocyte RAB6A
Mean 34.8
Standard deviation 13
Values 53 37 37 26 20
[16]
HepG2 RAB6A
Mean 70.3
Standard deviation 2
Values 69 72
[17]
HepG2.C3A RAB6A
Mean 57.8
Standard deviation 10
Values 65 50
[18]
HuH.7 RAB6A
Mean 48.1
Standard deviation 6.7
Values 48 55 42
[19]
SNU475 RAB6A
Mean 40.5
Standard deviation 6.8
Values 45 36
[20]
THLE RAB6A
Mean 42.4
Standard deviation 2.6
Values 41 44
[21]
liver RAB6A
Mean 61.4
Standard deviation 16
Values 64 49 82 50
[22]
ref_hepatocyte B4GALT1
Mean 24.8
Standard deviation 5.2
Values 17 26 28 31 23
[23]
HepG2 B4GALT1
Mean 50.3
Standard deviation 11
Values 58 42
[24]
HepG2.C3A B4GALT1
Mean 41.3
Standard deviation 12
Values 50 32
[25]
HuH.7 B4GALT1
Mean 76.8
Standard deviation 16
Values 83 90 58
[26]
SNU475 B4GALT1
Mean 44.1
Standard deviation 8.5
Values 50 38
[27]
THLE B4GALT1
Mean 172
Standard deviation 9.4
Values 1.7e+02 1.8e+02
[28]
liver B4GALT1
Mean 55
Standard deviation 12
Values 52 46 73 49
[29]
ref_hepatocyte ATP2A2
Mean 18.4
Standard deviation 5.6
Values 18 23 25 15 11
[30]
HepG2 ATP2A2
Mean 121
Standard deviation 0.14
Values 1.2e+02 1.2e+02
[31]
HepG2.C3A ATP2A2
Mean 98.3
Standard deviation 7.8
Values 93 1e+02
[32]
HuH.7 ATP2A2
Mean 116
Standard deviation 22
Values 1.4e+02 98 1.1e+02
[33]
SNU475 ATP2A2
Mean 238
Standard deviation 1.4e+02
Values 3.4e+02 1.4e+02
[34]
THLE ATP2A2
Mean 127
Standard deviation 27
Values 1.1e+02 1.5e+02
[35]
liver ATP2A2
Mean 87.2
Standard deviation 53
Values 47 1e+02 43 1.6e+02
[36]
ref_hepatocyte SEL1L
Mean 15.3
Standard deviation 6
Values 6.6 15 14 23 17
[37]
HepG2 SEL1L
Mean 42.2
Standard deviation 13
Values 33 51
[38]
HepG2.C3A SEL1L
Mean 50.8
Standard deviation 5.2
Values 47 54
[39]
HuH.7 SEL1L
Mean 46.1
Standard deviation 17
Values 45 64 30
[40]
SNU475 SEL1L
Mean 54.8
Standard deviation 20
Values 69 40
[41]
THLE SEL1L
Mean 49.6
Standard deviation 0.3
Values 49 50
[42]
liver SEL1L
Mean 154
Standard deviation 39
Values 1.1e+02 2e+02 1.4e+02 1.7e+02
[43]
ref_hepatocyte RFNG
Mean 14.1
Standard deviation 11
Values 3.4 2.1 15 22 28
[44]
HepG2 RFNG
Mean 36.7
Standard deviation 6.1
Values 41 32
[45]
HepG2.C3A RFNG
Mean 42
Standard deviation 19
Values 55 29
[46]
HuH.7 RFNG
Mean 8.62
Standard deviation 0.48
Values 8.1 8.7 9
[47]
SNU475 RFNG
Mean 7.36
Standard deviation 1.8
Values 8.6 6.1
[48]
THLE RFNG
Mean 7.28
Standard deviation 1.4
Values 8.3 6.3
[49]
liver RFNG
Mean 8.99
Standard deviation 5.7
Values 17 5 7.9 5.8
[50]
ref_hepatocyte ST3GAL6
Mean 10.6
Standard deviation 7.2
Values 10 6.7 1 16 19
[51]
HepG2 ST3GAL6
Mean 4.65
Standard deviation 0.55
Values 4.3 5
[52]
HepG2.C3A ST3GAL6
Mean 14
Standard deviation 2
Values 15 13
[53]
HuH.7 ST3GAL6
Mean 25.5
Standard deviation 5.8
Values 29 19 29
[54]
SNU475 ST3GAL6
Mean 0.188
Standard deviation 0.12
Values 0.1 0.27
[55]
THLE ST3GAL6
Mean 7.43
Standard deviation 1.1
Values 6.7 8.2
[56]
liver ST3GAL6
Mean 23.4
Standard deviation 8.2
Values 33 15 18 28
[57]
ref_hepatocyte ST3GAL4
Mean 6.03
Standard deviation 3.2
Values 2.5 9.8 5.5 8.8 3.5
[58]
HepG2 ST3GAL4
Mean 7.77
Standard deviation 0.82
Values 8.3 7.2
[59]
HepG2.C3A ST3GAL4
Mean 4.98
Standard deviation 0.18
Values 4.9 5.1
[60]
HuH.7 ST3GAL4
Mean 1.21
Standard deviation 0.13
Values 1.3 1.2 1.1
[61]
SNU475 ST3GAL4
Mean 17.1
Standard deviation 3
Values 15 19
[62]
THLE ST3GAL4
Mean 12.4
Standard deviation 0.71
Values 12 13
[63]
liver ST3GAL4
Mean 3.98
Standard deviation 1.1
Values 3.7 4 2.8 5.4
[64]
ref_hepatocyte NOTCH2
Mean 5.26
Standard deviation 4
Values 1.6 11 7.1 2.4 3.7
[65]
HepG2 NOTCH2
Mean 12.7
Standard deviation 3.4
Values 15 10
[66]
HepG2.C3A NOTCH2
Mean 0.213
Standard deviation 0.12
Values 0.13 0.3
[67]
HuH.7 NOTCH2
Mean 36.5
Standard deviation 12
Values 44 43 23
[68]
SNU475 NOTCH2
Mean 79.3
Standard deviation 13
Values 88 70
[69]
THLE NOTCH2
Mean 154
Standard deviation 35
Values 1.3e+02 1.8e+02
[70]
liver NOTCH2
Mean 74.9
Standard deviation 42
Values 39 1.2e+02 39 99
[71]
ref_hepatocyte ST3GAL3
Mean 2.23
Standard deviation 1
Values 2.5 0.54 2.3 2.6 3.2
[72]
HepG2 ST3GAL3
Mean 4.58
Standard deviation 1.4
Values 5.5 3.6
[73]
HepG2.C3A ST3GAL3
Mean 4.78
Standard deviation 2.4
Values 6.5 3.1
[74]
HuH.7 ST3GAL3
Mean 5.06
Standard deviation 0.7
Values 5.6 4.3 5.3
[75]
SNU475 ST3GAL3
Mean 3.56
Standard deviation 0.78
Values 4.1 3
[76]
THLE ST3GAL3
Mean 5.76
Standard deviation 0.51
Values 5.4 6.1
[77]
liver ST3GAL3
Mean 2.51
Standard deviation 0.3
Values 2.9 2.4 2.5 2.2
[78]
ref_hepatocyte NOTCH1
Mean 0.644
Standard deviation 0.25
Values 0.33 0.55 0.55 0.91 0.89
[79]
HepG2 NOTCH1
Mean 5.33
Standard deviation 3.7
Values 8 2.7
[80]
HepG2.C3A NOTCH1
Mean 2.12
Standard deviation 0.1
Values 2.1 2.2
[81]
HuH.7 NOTCH1
Mean 5.14
Standard deviation 1.4
Values 5.4 6.4 3.6
[82]
SNU475 NOTCH1
Mean 7.09
Standard deviation 0.64
Values 6.6 7.5
[83]
THLE NOTCH1
Mean 10.2
Standard deviation 2.2
Values 8.6 12
[84]
liver NOTCH1
Mean 22.8
Standard deviation 16
Values 10 31 8.8 41
[85]
ref_hepatocyte MFNG
Mean 0.579
Standard deviation 0.54
Values 0.11 0 0.64 0.84 1.3
[86]
HepG2 MFNG
Mean 0.955
Standard deviation 0.32
Values 1.2 0.73
[87]
HepG2.C3A MFNG
Mean 55.2
Standard deviation 18
Values 68 42
[88]
HuH.7 MFNG
Mean 1.19
Standard deviation 0.54
Values 0.7 1.8 1.1
[89]
SNU475 MFNG
Mean 0.131
Standard deviation 0.0055
Values 0.13 0.13
[90]
THLE MFNG
Mean 0.0432
Standard deviation 0.031
Values 0.065 0.021
[91]
liver MFNG
Mean 4.61
Standard deviation 2.8
Values 4.7 2.9 8.6 2.3
[92]
ref_hepatocyte LFNG
Mean 0.371
Standard deviation 0.36
Values 0.059 0 0.64 0.34 0.82
[93]
HepG2 LFNG
Mean 4.48
Standard deviation 0.77
Values 5 3.9
[94]
HepG2.C3A LFNG
Mean 0.275
Standard deviation 0.14
Values 0.17 0.38
[95]
HuH.7 LFNG
Mean 1.44
Standard deviation 1.1
Values 2 0.19 2.2
[96]
SNU475 LFNG
Mean 0.354
Standard deviation 0.1
Values 0.28 0.43
[97]
THLE LFNG
Mean 1.35
Standard deviation 0.078
Values 1.4 1.3
[98]
liver LFNG
Mean 0.658
Standard deviation 0.45
Values 0.21 1 0.33 1.1
[99]
ref_hepatocyte ATP2A3
Mean 0.237
Standard deviation 0.3
Values 0 0 0.18 0.26 0.74
[100]
HepG2 ATP2A3
Mean 2.28
Standard deviation 2.9
Values 4.4 0.21
[101]
HepG2.C3A ATP2A3
Mean 0.09
Standard deviation 0.051
Values 0.13 0.054
[102]
HuH.7 ATP2A3
Mean 1.23
Standard deviation 0.6
Values 1.7 0.56 1.4
[103]
SNU475 ATP2A3
Mean 0.941
Standard deviation 0.41
Values 1.2 0.65
[104]
THLE ATP2A3
Mean 0.805
Standard deviation 0.12
Values 0.72 0.89
[105]
liver ATP2A3
Mean 2.13
Standard deviation 0.64
Values 3 1.6 1.7 2.3
[106]
ref_hepatocyte NOTCH3
Mean 0.138
Standard deviation 0.22
Values 0.028 0.028 0.54 0.043 0.057
[107]
HepG2 NOTCH3
Mean 5.12
Standard deviation 6.5
Values 9.7 0.55
[108]
HepG2.C3A NOTCH3
Mean 0.222
Standard deviation 0.057
Values 0.26 0.18
[109]
HuH.7 NOTCH3
Mean 13.3
Standard deviation 4.1
Values 18 9.9 12
[110]
SNU475 NOTCH3
Mean 19.3
Standard deviation 5.2
Values 23 16
[111]
THLE NOTCH3
Mean 4.85
Standard deviation 2.7
Values 6.7 3
[112]
liver NOTCH3
Mean 3.33
Standard deviation 2.3
Values 2 4.1 1.1 6.2
[113]
ref_hepatocyte NOTCH4
Mean 0.117
Standard deviation 0.16
Values 0 0 0.03 0.18 0.37
[114]
HepG2 NOTCH4
Mean 0.383
Standard deviation 0.29
Values 0.59 0.18
[115]
HepG2.C3A NOTCH4
Mean 0.505
Standard deviation 0.14
Values 0.6 0.41
[116]
HuH.7 NOTCH4
Mean 0.0776
Standard deviation 0.023
Values 0.074 0.1 0.056
[117]
SNU475 NOTCH4
Mean 0.0534
Standard deviation 0.0034
Values 0.051 0.056
[118]
THLE NOTCH4
Mean 0.365
Standard deviation 0.019
Values 0.38 0.35
[119]
liver NOTCH4
Mean 12.3
Standard deviation 1.6
Values 13 11 11 14
[120]
ref_hepatocyte ATP2A1
Mean 0.035
Standard deviation 0.058
Values 0.13 0 0 0 0.041
[121]
HepG2 ATP2A1
Mean 1.82
Standard deviation 0.53
Values 2.2 1.4
[122]
HepG2.C3A ATP2A1
Mean 6.18
Standard deviation 3.2
Values 8.4 3.9
[123]
HuH.7 ATP2A1
Mean 0.501
Standard deviation 0.093
Values 0.39 0.55 0.56
[124]
SNU475 ATP2A1
Mean 0.312
Standard deviation 0.1
Values 0.38 0.24
[125]
THLE ATP2A1
Mean 0.471
Standard deviation 0.15
Values 0.58 0.36
[126]
liver ATP2A1
Mean 0.15
Standard deviation 0.094
Values 0.094 0.26 0.051 0.2