REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNG5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 -0.89[1] -0.77[2] -1.69[3] -2.03[4] -2.36[5] -0.69[6]
2 GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [7] 1.33[8] 1.29[9] 0.75[10] 1.06[11] 0.79[12] -0.33[13]
3 GNB2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [14] -0.29[15] -0.60[16] -0.31[17] -0.59[18] -0.60[19] -0.70[20]
4 GNG10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 -4.38[21] -4.16[22] -4.51[23] -4.03[24] -3.29[25] -3.44[26]
5 GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 -4.43[27] -7.42[28] 0.47[29] 1.66[30] 1.68[31] 1.39[32]
6 GNB5 Guanine nucleotide-binding protein subunit beta-5 [33] 0.42[34] 0.39[35] 1.36[36] 0.57[37] 0.62[38] 1.79[39]
7 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [40] 2.32[41] 1.75[42] 2.16[43] 2.49[44] 2.06[45] 1.63[46]
8 GNG11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 -7.86[47] -7.92[48] -7.29[49] 2.04[50] 3.29[51] 3.14[52]
9 PLCB1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [53] 3.11[54] 4.67[55] 4.05[56] 0.56[57] 0.98[58] 3.39[59]
10 GNG7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 1.87[60] 1.46[61] 2.21[62] -2.46[63] -1.91[64] 0.93[65]
11 GNG4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 3.79[66] 1.49[67] 5.24[68] 1.03[69] -1.15[70] -1.65[71]
12 PLCB2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [72] -1.30[73] -6.15[74] -8.04[75] -2.16[76] -2.94[77] 3.14[78]
13 GNB4 Guanine nucleotide-binding protein subunit beta-4 [79] -0.05[80] 0.38[81] 1.33[82] 2.46[83] 5.12[84] 4.99[85]
14 GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 -5.96[86] -6.90[87] [88] 2.90[89] 2.30[90] 3.68[91]
15 GNGT2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [92] [93] [94] -2.29[95] -7.03[96] 1.01[97]
16 GNG3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 -0.54[98] 1.24[99] -1.05[100] -0.92[101] -1.31[102] 0.82[103]
17 GNB3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [104] 1.91[105] 4.10[106] 3.35[107] 0.79[108] 3.43[109] -0.78[110]
18 GRIK3 Glutamate receptor ionotropic, kainate 3 [111] [112] [113] [114] [115] [116] [117]
19 GNG13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [118] [119] [120] [121] [122] [123]
20 GNG8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [124] [125] [126] [127] [128] [129]
21 GNGT1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 [130] [131] [132] [133] [134] [135] [136]
[1]
ref_hepatocyte GNG5
Mean 71
Standard deviation 24
Values 60 35 85 91 85
[2]
HepG2 GNG5
Mean 68.1
Standard deviation 11
Values 60 76
[3]
HepG2.C3A GNG5
Mean 68.6
Standard deviation 10
Values 61 76
[4]
HuH.7 GNG5
Mean 36.1
Standard deviation 6.8
Values 38 28 42
[5]
SNU475 GNG5
Mean 37.2
Standard deviation 3.1
Values 39 35
[6]
THLE GNG5
Mean 34.8
Standard deviation 0.49
Values 34 35
[7]
liver GNG5
Mean 33.6
Standard deviation 38
Values 75 1.4 56 1.4
[8]
ref_hepatocyte GNB1
Mean 42.7
Standard deviation 15
Values 44 60 53 31 24
[9]
HepG2 GNB1
Mean 190
Standard deviation 15
Values 2e+02 1.8e+02
[10]
HepG2.C3A GNB1
Mean 171
Standard deviation 4.5
Values 1.7e+02 1.7e+02
[11]
HuH.7 GNB1
Mean 118
Standard deviation 23
Values 1.4e+02 93 1.2e+02
[12]
SNU475 GNB1
Mean 191
Standard deviation 19
Values 2e+02 1.8e+02
[13]
THLE GNB1
Mean 185
Standard deviation 12
Values 1.8e+02 1.9e+02
[14]
liver GNB1
Mean 25.7
Standard deviation 5
Values 31 25 19 27
[15]
ref_hepatocyte GNB2
Mean 38.8
Standard deviation 20
Values 15 25 41 67 46
[16]
HepG2 GNB2
Mean 56.5
Standard deviation 6.2
Values 61 52
[17]
HepG2.C3A GNB2
Mean 42.3
Standard deviation 7.9
Values 48 37
[18]
HuH.7 GNB2
Mean 51.2
Standard deviation 3.5
Values 50 49 55
[19]
SNU475 GNB2
Mean 55.4
Standard deviation 5.7
Values 59 51
[20]
THLE GNB2
Mean 64.6
Standard deviation 5.2
Values 61 68
[21]
liver GNB2
Mean 18.2
Standard deviation 7.1
Values 24 11 25 13
[22]
ref_hepatocyte GNG10
Mean 36.1
Standard deviation 25
Values 54 68 12 12 34
[23]
HepG2 GNG10
Mean 3.07
Standard deviation 0.45
Values 2.8 3.4
[24]
HepG2.C3A GNG10
Mean 3.33
Standard deviation 1.3
Values 2.4 4.3
[25]
HuH.7 GNG10
Mean 2.59
Standard deviation 0.11
Values 2.6 2.5 2.7
[26]
SNU475 GNG10
Mean 4.73
Standard deviation 1.4
Values 5.8 3.7
[27]
THLE GNG10
Mean 9.34
Standard deviation 0.66
Values 8.9 9.8
[28]
liver GNG10
Mean 2.53
Standard deviation 1.2
Values 3.6 2.1 3.3 1.1
[29]
ref_hepatocyte GNG12
Mean 16.5
Standard deviation 18
Values 0.58 46 23 5.6 7.3
[30]
HepG2 GNG12
Mean 1.35
Standard deviation 0.72
Values 1.9 0.84
[31]
HepG2.C3A GNG12
Mean 0.158
Standard deviation 0.011
Values 0.17 0.15
[32]
HuH.7 GNG12
Mean 37.3
Standard deviation 6.6
Values 44 36 31
[33]
SNU475 GNG12
Mean 111
Standard deviation 32
Values 1.3e+02 89
[34]
THLE GNG12
Mean 133
Standard deviation 28
Values 1.1e+02 1.5e+02
[35]
liver GNG12
Mean 32.7
Standard deviation 9.9
Values 36 32 43 19
[36]
ref_hepatocyte GNB5
Mean 4.79
Standard deviation 2.5
Values 6.3 6.9 2 6.5 2.2
[37]
HepG2 GNB5
Mean 11.3
Standard deviation 2.9
Values 13 9.2
[38]
HepG2.C3A GNB5
Mean 10.4
Standard deviation 1.2
Values 11 9.5
[39]
HuH.7 GNB5
Mean 20.1
Standard deviation 2.5
Values 20 23 18
[40]
SNU475 GNB5
Mean 15.2
Standard deviation 0.29
Values 15 15
[41]
THLE GNB5
Mean 18.5
Standard deviation 0.68
Values 18 19
[42]
liver GNB5
Mean 12.6
Standard deviation 4.4
Values 13 12 18 7.3
[43]
ref_hepatocyte PLCB3
Mean 1.72
Standard deviation 1
Values 3.3 2 1.6 0.84 0.87
[44]
HepG2 PLCB3
Mean 15.2
Standard deviation 2.5
Values 13 17
[45]
HepG2.C3A PLCB3
Mean 9.48
Standard deviation 0.28
Values 9.3 9.7
[46]
HuH.7 PLCB3
Mean 12.5
Standard deviation 4.9
Values 15 6.9 16
[47]
SNU475 PLCB3
Mean 20.7
Standard deviation 4.4
Values 24 18
[48]
THLE PLCB3
Mean 18.1
Standard deviation 1.4
Values 17 19
[49]
liver PLCB3
Mean 4.04
Standard deviation 2.9
Values 1.7 5.4 1.5 7.5
[50]
ref_hepatocyte GNG11
Mean 1.51
Standard deviation 1.6
Values 0 0 1.3 3.2 3
[51]
HepG2 GNG11
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[52]
HepG2.C3A GNG11
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[53]
HuH.7 GNG11
Mean 0.0158
Standard deviation 0.022
Values 0.041 0.0064 0
[54]
SNU475 GNG11
Mean 13.3
Standard deviation 2
Values 12 15
[55]
THLE GNG11
Mean 37.1
Standard deviation 6.4
Values 33 42
[56]
liver GNG11
Mean 10.1
Standard deviation 8.8
Values 16 3.1 19 2
[57]
ref_hepatocyte PLCB1
Mean 0.993
Standard deviation 1.3
Values 3.2 0.71 0.37 0.15 0.52
[58]
HepG2 PLCB1
Mean 15.2
Standard deviation 2.6
Values 13 17
[59]
HepG2.C3A PLCB1
Mean 41.8
Standard deviation 4.5
Values 45 39
[60]
HuH.7 PLCB1
Mean 26.9
Standard deviation 8.9
Values 26 36 19
[61]
SNU475 PLCB1
Mean 3.13
Standard deviation 0.39
Values 3.4 2.9
[62]
THLE PLCB1
Mean 4.93
Standard deviation 0.69
Values 5.4 4.4
[63]
liver PLCB1
Mean 7.93
Standard deviation 2.5
Values 8.6 11 6 6
[64]
ref_hepatocyte GNG7
Mean 0.972
Standard deviation 0.89
Values 2.2 0.22 0.098 0.76 1.6
[65]
HepG2 GNG7
Mean 6.31
Standard deviation 1.2
Values 7.2 5.5
[66]
HepG2.C3A GNG7
Mean 4.41
Standard deviation 1.7
Values 5.6 3.2
[67]
HuH.7 GNG7
Mean 7.39
Standard deviation 1.1
Values 8.1 6.1 7.9
[68]
SNU475 GNG7
Mean 0.379
Standard deviation 0.19
Values 0.51 0.24
[69]
THLE GNG7
Mean 0.654
Standard deviation 0.35
Values 0.9 0.41
[70]
liver GNG7
Mean 1.4
Standard deviation 0.99
Values 2.8 0.53 1.3 1
[71]
ref_hepatocyte GNG4
Mean 0.665
Standard deviation 1.2
Values 2.8 0.17 0.098 0.15 0.11
[72]
HepG2 GNG4
Mean 16.3
Standard deviation 4.5
Values 19 13
[73]
HepG2.C3A GNG4
Mean 3.08
Standard deviation 0.29
Values 2.9 3.3
[74]
HuH.7 GNG4
Mean 41.2
Standard deviation 8.1
Values 48 32 43
[75]
SNU475 GNG4
Mean 2.92
Standard deviation 0.47
Values 3.3 2.6
[76]
THLE GNG4
Mean 0.755
Standard deviation 0.19
Values 0.89 0.62
[77]
liver GNG4
Mean 0.161
Standard deviation 0.098
Values 0.024 0.26 0.18 0.19
[78]
ref_hepatocyte PLCB2
Mean 0.44
Standard deviation 0.47
Values 0 0.049 0.42 0.57 1.2
[79]
HepG2 PLCB2
Mean 0.316
Standard deviation 0.31
Values 0.53 0.099
[80]
HepG2.C3A PLCB2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[81]
HuH.7 PLCB2
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[82]
SNU475 PLCB2
Mean 0.211
Standard deviation 0.062
Values 0.26 0.17
[83]
THLE PLCB2
Mean 0.145
Standard deviation 0.029
Values 0.12 0.16
[84]
liver PLCB2
Mean 2.94
Standard deviation 1.6
Values 1.8 3.5 1.5 4.9
[85]
ref_hepatocyte GNB4
Mean 0.389
Standard deviation 0.25
Values 0.16 0.31 0.7 0.17 0.61
[86]
HepG2 GNB4
Mean 0.666
Standard deviation 0.063
Values 0.71 0.62
[87]
HepG2.C3A GNB4
Mean 0.835
Standard deviation 0.043
Values 0.87 0.8
[88]
HuH.7 GNB4
Mean 1.6
Standard deviation 0.14
Values 1.6 1.7 1.5
[89]
SNU475 GNB4
Mean 4.59
Standard deviation 0.038
Values 4.6 4.6
[90]
THLE GNB4
Mean 34.3
Standard deviation 7.5
Values 29 40
[91]
liver GNB4
Mean 9.42
Standard deviation 4.4
Values 4.9 15 7 11
[92]
ref_hepatocyte GNG2
Mean 0.352
Standard deviation 0.41
Values 0 0.06 0.53 0.18 0.99
[93]
HepG2 GNG2
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[94]
HepG2.C3A GNG2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[95]
HuH.7 GNG2
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 GNG2
Mean 5.62
Standard deviation 1.4
Values 4.6 6.6
[97]
THLE GNG2
Mean 4.37
Standard deviation 0.87
Values 5 3.8
[98]
liver GNG2
Mean 3.44
Standard deviation 0.91
Values 3.5 3.6 4.4 2.2
[99]
ref_hepatocyte GNGT2
Mean 0.154
Standard deviation 0.23
Values 0 0 0.06 0.16 0.54
[100]
HepG2 GNGT2
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A GNGT2
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 GNGT2
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 GNGT2
Mean 0.0673
Standard deviation 0.062
Values 0.023 0.11
[104]
THLE GNGT2
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[105]
liver GNGT2
Mean 0.235
Standard deviation 0.19
Values 0.35 0.086 0.44 0.066
[106]
ref_hepatocyte GNG3
Mean 0.127
Standard deviation 0.2
Values 0 0 0 0.46 0.18
[107]
HepG2 GNG3
Mean 0.155
Standard deviation 0.032
Values 0.18 0.13
[108]
HepG2.C3A GNG3
Mean 0.493
Standard deviation 0.33
Values 0.73 0.26
[109]
HuH.7 GNG3
Mean 0.101
Standard deviation 0.06
Values 0.033 0.15 0.12
[110]
SNU475 GNG3
Mean 0.144
Standard deviation 0.053
Values 0.18 0.11
[111]
THLE GNG3
Mean 0.13
Standard deviation 0.018
Values 0.14 0.12
[112]
liver GNG3
Mean 0.17
Standard deviation 0.089
Values 0.047 0.26 0.21 0.17
[113]
ref_hepatocyte GNB3
Mean 0.0571
Standard deviation 0.11
Values 0.24 0 0 0 0.041
[114]
HepG2 GNB3
Mean 0.379
Standard deviation 0.11
Values 0.3 0.45
[115]
HepG2.C3A GNB3
Mean 1.61
Standard deviation 0.27
Values 1.4 1.8
[116]
HuH.7 GNB3
Mean 0.95
Standard deviation 0.47
Values 0.98 0.47 1.4
[117]
SNU475 GNB3
Mean 0.211
Standard deviation 0.003
Values 0.21 0.21
[118]
THLE GNB3
Mean 1.55
Standard deviation 0.56
Values 1.9 1.1
[119]
liver GNB3
Mean 0.0253
Standard deviation 0.019
Values 0.047 0.029 0.026 0
[120]
ref_hepatocyte GRIK3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 GRIK3
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A GRIK3
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 GRIK3
Mean 0
Standard deviation 0
Values 0 0 0
[124]
SNU475 GRIK3
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[125]
THLE GRIK3
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[126]
liver GRIK3
Mean 0.0265
Standard deviation 0.053
Values 0 0 0 0.11
[127]
ref_hepatocyte GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 GNG13
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A GNG13
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 GNG13
Mean 0.0152
Standard deviation 0.017
Values 0.033 0.013 0
[131]
SNU475 GNG13
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[132]
THLE GNG13
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[133]
liver GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 GNG8
Mean 0
Standard deviation 0
Values 0 0
[136]
HepG2.C3A GNG8
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 GNG8
Mean 0
Standard deviation 0
Values 0 0 0
[138]
SNU475 GNG8
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[139]
THLE GNG8
Mean 0
Standard deviation 0
Values 0 0
[140]
liver GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0
[141]
ref_hepatocyte GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 GNGT1
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A GNGT1
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 GNGT1
Mean 0.0409
Standard deviation 0.035
Values 0.0082 0.077 0.037
[145]
SNU475 GNGT1
Mean 0.0679
Standard deviation 0.0043
Values 0.065 0.071
[146]
THLE GNGT1
Mean 0
Standard deviation 0
Values 0 0
[147]
liver GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0