REACTOME_PREGNENOLONE_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TSPO Translocator protein [1] -2.90[2] -3.00[3] -1.32[4] -1.06[5] -1.58[6] -1.03[7]
2 STARD4 StAR-related lipid transfer protein 4 [8] -4.00[9] -0.41[10] 0.03[11] -2.90[12] -4.22[13] -0.10[14]
3 STARD3NL STARD3 N-terminal-like protein [15] -0.68[16] -0.27[17] 0.75[18] -0.11[19] -0.86[20] -0.98[21]
4 FDX1 Adrenodoxin, mitochondrial [22] -1.28[23] -1.23[24] -1.62[25] -0.57[26] -1.15[27] 1.51[28]
5 FDXR NADPH:adrenodoxin oxidoreductase, mitochondrial [29] 2.02[30] 1.84[31] -0.17[32] -2.18[33] -1.59[34] -1.21[35]
6 AKR1B1 Aldose reductase [36] 2.10[37] 1.50[38] -1.86[39] 2.68[40] 3.03[41] -0.38[42]
7 STARD3 StAR-related lipid transfer protein 3 [43] 0.41[44] 0.71[45] 2.18[46] 0.00[47] -0.50[48] 0.85[49]
8 STAR Steroidogenic acute regulatory protein, mitochondrial [50] 0.18[51] 0.08[52] -2.44[53] -3.43[54] -1.51[55] -2.78[56]
9 CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial [57] -1.24[58] -3.27[59] [60] -3.54[61] 0.01[62] 1.18[63]
10 STARD6 StAR-related lipid transfer protein 6 [64] [65] [66] [67] [68] [69] [70]
11 FDX2 Ferredoxin-2, mitochondrial [71] [72] [73] [74] [75] [76] [77]
12 TSPOAP1 Peripheral-type benzodiazepine receptor-associated protein 1 [78] [79] [80] [81] [82] [83] [84]
[1]
ref_hepatocyte TSPO
Mean 26
Standard deviation 23
Values 0.68 61 12 32 24
[2]
HepG2 TSPO
Mean 11.5
Standard deviation 7.1
Values 17 6.5
[3]
HepG2.C3A TSPO
Mean 6.8
Standard deviation 4
Values 9.6 4
[4]
HuH.7 TSPO
Mean 9.58
Standard deviation 3.7
Values 8.3 6.7 14
[5]
SNU475 TSPO
Mean 27.8
Standard deviation 9.5
Values 34 21
[6]
THLE TSPO
Mean 30.7
Standard deviation 8.8
Values 24 37
[7]
liver TSPO
Mean 11.1
Standard deviation 8.9
Values 19 3.2 19 3.5
[8]
ref_hepatocyte STARD4
Mean 13.9
Standard deviation 16
Values 38 23 2.5 2.6 3.9
[9]
HepG2 STARD4
Mean 2.87
Standard deviation 2.2
Values 1.3 4.4
[10]
HepG2.C3A STARD4
Mean 22
Standard deviation 2
Values 21 23
[11]
HuH.7 STARD4
Mean 13
Standard deviation 3.4
Values 13 16 9.8
[12]
SNU475 STARD4
Mean 4.16
Standard deviation 2.6
Values 6 2.3
[13]
THLE STARD4
Mean 2.63
Standard deviation 0.2
Values 2.5 2.8
[14]
liver STARD4
Mean 11.3
Standard deviation 4.4
Values 6.8 13 8.8 17
[15]
ref_hepatocyte STARD3NL
Mean 12.2
Standard deviation 11
Values 30 14 7.9 4.4 4.7
[16]
HepG2 STARD3NL
Mean 25.2
Standard deviation 3.6
Values 23 28
[17]
HepG2.C3A STARD3NL
Mean 21.2
Standard deviation 3.8
Values 19 24
[18]
HuH.7 STARD3NL
Mean 18.9
Standard deviation 1.2
Values 18 19 20
[19]
SNU475 STARD3NL
Mean 25.2
Standard deviation 2.7
Values 27 23
[20]
THLE STARD3NL
Mean 23.7
Standard deviation 3.4
Values 21 26
[21]
liver STARD3NL
Mean 5.38
Standard deviation 2.9
Values 8.1 3.7 7.5 2.2
[22]
ref_hepatocyte FDX1
Mean 11.4
Standard deviation 6.1
Values 10 11 2.2 14 19
[23]
HepG2 FDX1
Mean 15.5
Standard deviation 0.65
Values 15 16
[24]
HepG2.C3A FDX1
Mean 10.2
Standard deviation 2.3
Values 8.6 12
[25]
HuH.7 FDX1
Mean 3.41
Standard deviation 0.095
Values 3.3 3.4 3.5
[26]
SNU475 FDX1
Mean 17.1
Standard deviation 1.7
Values 18 16
[27]
THLE FDX1
Mean 18.1
Standard deviation 3.7
Values 15 21
[28]
liver FDX1
Mean 28.4
Standard deviation 18
Values 44 15 44 12
[29]
ref_hepatocyte FDXR
Mean 7.28
Standard deviation 6.2
Values 18 3.2 2.7 8.3 4.5
[30]
HepG2 FDXR
Mean 97.8
Standard deviation 8.7
Values 92 1e+02
[31]
HepG2.C3A FDXR
Mean 54.6
Standard deviation 14
Values 45 64
[32]
HuH.7 FDXR
Mean 5.93
Standard deviation 2.4
Values 6.5 3.4 8
[33]
SNU475 FDXR
Mean 3.59
Standard deviation 0.45
Values 3.9 3.3
[34]
THLE FDXR
Mean 8.51
Standard deviation 1.3
Values 9.4 7.6
[35]
liver FDXR
Mean 2.74
Standard deviation 1.3
Values 3.3 2 4.4 1.3
[36]
ref_hepatocyte AKR1B1
Mean 6.91
Standard deviation 5.9
Values 12 15 2.7 3.4 2
[37]
HepG2 AKR1B1
Mean 98.1
Standard deviation 19
Values 1.1e+02 85
[38]
HepG2.C3A AKR1B1
Mean 40.9
Standard deviation 16
Values 29 52
[39]
HuH.7 AKR1B1
Mean 1.75
Standard deviation 0.56
Values 2.2 1.1 1.9
[40]
SNU475 AKR1B1
Mean 99.2
Standard deviation 35
Values 75 1.2e+02
[41]
THLE AKR1B1
Mean 199
Standard deviation 6.6
Values 1.9e+02 2e+02
[42]
liver AKR1B1
Mean 4.63
Standard deviation 2.8
Values 6.6 1.8 7.5 2.6
[43]
ref_hepatocyte STARD3
Mean 6.24
Standard deviation 1.6
Values 5.4 4.6 6.1 8.9 6.1
[44]
HepG2 STARD3
Mean 27.5
Standard deviation 1.8
Values 29 26
[45]
HepG2.C3A STARD3
Mean 21.3
Standard deviation 7
Values 26 16
[46]
HuH.7 STARD3
Mean 25.9
Standard deviation 1.8
Values 24 26 28
[47]
SNU475 STARD3
Mean 13.9
Standard deviation 1.7
Values 15 13
[48]
THLE STARD3
Mean 15.5
Standard deviation 0.55
Values 15 16
[49]
liver STARD3
Mean 9.79
Standard deviation 4.2
Values 13 5.8 13 6.6
[50]
ref_hepatocyte STAR
Mean 1.18
Standard deviation 2
Values 4.8 0.5 0.17 0.13 0.33
[51]
HepG2 STAR
Mean 4.43
Standard deviation 2.3
Values 2.8 6
[52]
HepG2.C3A STAR
Mean 2.62
Standard deviation 0.42
Values 2.9 2.3
[53]
HuH.7 STAR
Mean 0.2
Standard deviation 0.04
Values 0.19 0.17 0.24
[54]
SNU475 STAR
Mean 0.245
Standard deviation 0.084
Values 0.19 0.3
[55]
THLE STAR
Mean 1.46
Standard deviation 0.0069
Values 1.5 1.5
[56]
liver STAR
Mean 0.149
Standard deviation 0.075
Values 0.094 0.23 0.077 0.2
[57]
ref_hepatocyte CYP11A1
Mean 0.602
Standard deviation 0.44
Values 0.18 0.47 0.44 0.59 1.3
[58]
HepG2 CYP11A1
Mean 0.843
Standard deviation 0.49
Values 1.2 0.49
[59]
HepG2.C3A CYP11A1
Mean 0.131
Standard deviation 0.049
Values 0.17 0.097
[60]
HuH.7 CYP11A1
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 CYP11A1
Mean 0.115
Standard deviation 0.045
Values 0.083 0.15
[62]
THLE CYP11A1
Mean 2.14
Standard deviation 0.87
Values 2.8 1.5
[63]
liver CYP11A1
Mean 1.18
Standard deviation 0.65
Values 1.4 0.57 2 0.75
[64]
ref_hepatocyte STARD6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 STARD6
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A STARD6
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 STARD6
Mean 0.00761
Standard deviation 0.0083
Values 0.016 0.0064 0
[68]
SNU475 STARD6
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE STARD6
Mean 0.0219
Standard deviation 0.014
Values 0.012 0.032
[70]
liver STARD6
Mean 0
Standard deviation 0
Values 0 0 0 0
[71]
ref_hepatocyte FDX2
Missing
[72]
HepG2 FDX2
Missing
[73]
HepG2.C3A FDX2
Missing
[74]
HuH.7 FDX2
Missing
[75]
SNU475 FDX2
Missing
[76]
THLE FDX2
Missing
[77]
liver FDX2
Missing
[78]
ref_hepatocyte TSPOAP1
Missing
[79]
HepG2 TSPOAP1
Missing
[80]
HepG2.C3A TSPOAP1
Missing
[81]
HuH.7 TSPOAP1
Missing
[82]
SNU475 TSPOAP1
Missing
[83]
THLE TSPOAP1
Missing
[84]
liver TSPOAP1
Missing