REACTOME_PP2A_MEDIATED_DEPHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 0.65[1] 0.34[2] 0.71[3] 0.88[4] 0.45[5] -0.77[6]
2 PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.12[7] 0.08[8] -0.11[9] 0.41[10] 0.77[11] -1.02[12]
3 PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform -0.54[13] -1.02[14] -0.50[15] -0.79[16] -0.65[17] -1.90[18]
4 MLXIPL Carbohydrate-responsive element-binding protein [19] -2.01[20] 0.25[21] -1.28[22] -8.29[23] -6.31[24] 0.62[25]
5 PPP2R1B Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform 0.30[26] -0.35[27] 0.50[28] -0.06[29] -0.04[30] 2.02[31]
6 PPP2R5D Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform 1.10[32] 0.73[33] 0.73[34] 0.96[35] 1.08[36] -1.18[37]
7 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 [38] -2.94[39] -2.32[40] -6.99[41] -7.60[42] -7.95[43] -0.55[44]

[1]
ref_hepatocyte PPP2R1A
Mean 27.9
Standard deviation 5.4
Values 23 30 23 36 28
[2]
HepG2 PPP2R1A
Mean 107
Standard deviation 6.5
Values 1.1e+02 1e+02
[3]
HepG2.C3A PPP2R1A
Mean 84.7
Standard deviation 12
Values 93 76
[4]
HuH.7 PPP2R1A
Mean 77.2
Standard deviation 6.8
Values 84 70 78
[5]
SNU475 PPP2R1A
Mean 118
Standard deviation 14
Values 1.3e+02 1.1e+02
[6]
THLE PPP2R1A
Mean 83.3
Standard deviation 16
Values 72 94
[7]
liver PPP2R1A
Mean 43.9
Standard deviation 17
Values 51 30 65 30
[8]
ref_hepatocyte PPP2CA
Mean 27.3
Standard deviation 6.4
Values 27 38 22 24 25
[9]
HepG2 PPP2CA
Mean 72.8
Standard deviation 15
Values 62 83
[10]
HepG2.C3A PPP2CA
Mean 69.2
Standard deviation 19
Values 55 83
[11]
HuH.7 PPP2CA
Mean 42.8
Standard deviation 4.9
Values 43 38 48
[12]
SNU475 PPP2CA
Mean 83.9
Standard deviation 4.1
Values 81 87
[13]
THLE PPP2CA
Mean 102
Standard deviation 13
Values 92 1.1e+02
[14]
liver PPP2CA
Mean 36.1
Standard deviation 13
Values 49 27 46 23
[15]
ref_hepatocyte PPP2CB
Mean 25.5
Standard deviation 11
Values 15 43 27 17 26
[16]
HepG2 PPP2CB
Mean 43
Standard deviation 1.5
Values 44 42
[17]
HepG2.C3A PPP2CB
Mean 30.2
Standard deviation 0.78
Values 31 30
[18]
HuH.7 PPP2CB
Mean 30.6
Standard deviation 2.8
Values 28 34 30
[19]
SNU475 PPP2CB
Mean 34.2
Standard deviation 0.1
Values 34 34
[20]
THLE PPP2CB
Mean 35.7
Standard deviation 2.6
Values 37 34
[21]
liver PPP2CB
Mean 18.3
Standard deviation 7.2
Values 28 14 19 12
[22]
ref_hepatocyte MLXIPL
Mean 24.5
Standard deviation 24
Values 21 0.29 3.4 44 54
[23]
HepG2 MLXIPL
Mean 14.9
Standard deviation 1.1
Values 14 16
[24]
HepG2.C3A MLXIPL
Mean 69.5
Standard deviation 28
Values 89 50
[25]
HuH.7 MLXIPL
Mean 17.1
Standard deviation 3.9
Values 13 18 20
[26]
SNU475 MLXIPL
Mean 0.18
Standard deviation 0.047
Values 0.21 0.15
[27]
THLE MLXIPL
Mean 0.675
Standard deviation 0.52
Values 1 0.31
[28]
liver MLXIPL
Mean 101
Standard deviation 65
Values 1.9e+02 43 99 69
[29]
ref_hepatocyte PPP2R1B
Mean 12
Standard deviation 3.3
Values 7 14 11 15 13
[30]
HepG2 PPP2R1B
Mean 36.3
Standard deviation 12
Values 27 45
[31]
HepG2.C3A PPP2R1B
Mean 22.5
Standard deviation 5.6
Values 19 26
[32]
HuH.7 PPP2R1B
Mean 28.7
Standard deviation 4.1
Values 32 30 24
[33]
SNU475 PPP2R1B
Mean 26.6
Standard deviation 1.2
Values 26 27
[34]
THLE PPP2R1B
Mean 25.6
Standard deviation 5.7
Values 22 30
[35]
liver PPP2R1B
Mean 130
Standard deviation 78
Values 52 1.6e+02 82 2.2e+02
[36]
ref_hepatocyte PPP2R5D
Mean 7.67
Standard deviation 1.8
Values 11 7.4 6.7 6.6 6.7
[37]
HepG2 PPP2R5D
Mean 40.3
Standard deviation 5.9
Values 36 44
[38]
HepG2.C3A PPP2R5D
Mean 30.4
Standard deviation 4.1
Values 27 33
[39]
HuH.7 PPP2R5D
Mean 21.5
Standard deviation 4.4
Values 26 17 22
[40]
SNU475 PPP2R5D
Mean 34.4
Standard deviation 4.8
Values 38 31
[41]
THLE PPP2R5D
Mean 35.6
Standard deviation 5.6
Values 32 40
[42]
liver PPP2R5D
Mean 9.05
Standard deviation 4.1
Values 11 5.8 14 5.4
[43]
ref_hepatocyte PFKFB1
Mean 4.06
Standard deviation 5.2
Values 0.48 0.81 0.82 5.6 13
[44]
HepG2 PFKFB1
Mean 1.3
Standard deviation 0.56
Values 0.9 1.7
[45]
HepG2.C3A PFKFB1
Mean 1.94
Standard deviation 0.031
Values 2 1.9
[46]
HuH.7 PFKFB1
Mean 0.0538
Standard deviation 0.039
Values 0.016 0.051 0.094
[47]
SNU475 PFKFB1
Mean 0.0483
Standard deviation 0.0038
Values 0.051 0.046
[48]
THLE PFKFB1
Mean 0.0361
Standard deviation 0.0092
Values 0.03 0.043
[49]
liver PFKFB1
Mean 7.44
Standard deviation 2.6
Values 7.4 5.4 5.9 11