REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TSC22D1 TSC22 domain family protein 1 [1] -1.95[2] -0.79[3] -0.91[4] 0.13[5] -0.99[6] 0.23[7]
2 HHEX Hematopoietically-expressed homeobox protein HHEX [8] -1.42[9] 0.66[10] -0.24[11] -2.27[12] -4.17[13] 0.16[14]
3 POU5F1 POU domain, class 5, transcription factor 1 [15] -4.76[16] -1.42[17] -5.13[18] -2.61[19] -4.47[20] -3.42[21]
4 GATA6 Transcription factor GATA-6 [22] -1.28[23] -0.76[24] 0.59[25] 0.48[26] 1.74[27] 0.12[28]
5 DKK1 Dickkopf-related protein 1 [29] 4.11[30] 1.78[31] 0.81[32] 2.54[33] 3.71[34] -5.26[35]
6 NANOG Homeobox protein NANOG [36] -0.76[37] -0.28[38] -3.16[39] -1.07[40] -3.58[41] 0.10[42]
7 SOX2 Transcription factor SOX-2 [43] -3.51[44] [45] -1.08[46] 4.15[47] -6.42[48] -4.48[49]
8 EOMES Eomesodermin homolog [50] -1.62[51] 1.97[52] -1.72[53] -2.24[54] -4.37[55] 1.82[56]
9 CDX2 Homeobox protein CDX-2 [57] 1.56[58] 2.50[59] 10.51[60] 2.70[61] 0.33[62] -1.14[63]
10 GSC Homeobox protein goosecoid [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte TSC22D1
Mean 22.7
Standard deviation 5.2
Values 30 18 19 20 27
[2]
HepG2 TSC22D1
Mean 29.2
Standard deviation 1.6
Values 28 30
[3]
HepG2.C3A TSC22D1
Mean 23.2
Standard deviation 0.34
Values 23 23
[4]
HuH.7 TSC22D1
Mean 55.2
Standard deviation 5.5
Values 49 59 58
[5]
SNU475 TSC22D1
Mean 19.8
Standard deviation 5.3
Values 16 24
[6]
THLE TSC22D1
Mean 30.8
Standard deviation 5.1
Values 27 34
[7]
liver TSC22D1
Mean 33.4
Standard deviation 22
Values 61 14 41 17
[8]
ref_hepatocyte HHEX
Mean 14.9
Standard deviation 11
Values 16 3.5 4.7 21 29
[9]
HepG2 HHEX
Mean 27.6
Standard deviation 5.8
Values 24 32
[10]
HepG2.C3A HHEX
Mean 41.6
Standard deviation 0.72
Values 41 42
[11]
HuH.7 HHEX
Mean 57.8
Standard deviation 12
Values 48 71 54
[12]
SNU475 HHEX
Mean 2.46
Standard deviation 0.093
Values 2.4 2.5
[13]
THLE HHEX
Mean 2.22
Standard deviation 0.067
Values 2.2 2.3
[14]
liver HHEX
Mean 20.8
Standard deviation 17
Values 26 8.9 42 6.5
[15]
ref_hepatocyte POU5F1
Mean 4.56
Standard deviation 6.9
Values 0.79 0.49 17 0.95 3.9
[16]
HepG2 POU5F1
Mean 0.837
Standard deviation 0.12
Values 0.92 0.75
[17]
HepG2.C3A POU5F1
Mean 3.02
Standard deviation 1.1
Values 3.8 2.2
[18]
HuH.7 POU5F1
Mean 0.595
Standard deviation 0.041
Values 0.58 0.64 0.56
[19]
SNU475 POU5F1
Mean 0.596
Standard deviation 0.16
Values 0.71 0.48
[20]
THLE POU5F1
Mean 0.552
Standard deviation 0.15
Values 0.66 0.45
[21]
liver POU5F1
Mean 0.532
Standard deviation 0.43
Values 0.094 0.76 0.26 1
[22]
ref_hepatocyte GATA6
Mean 2.55
Standard deviation 0.5
Values 2.9 3.1 2.6 2.4 1.8
[23]
HepG2 GATA6
Mean 5.24
Standard deviation 0.41
Values 4.9 5.5
[24]
HepG2.C3A GATA6
Mean 2.68
Standard deviation 0.42
Values 3 2.4
[25]
HuH.7 GATA6
Mean 17.5
Standard deviation 0.9
Values 18 18 17
[26]
SNU475 GATA6
Mean 2.83
Standard deviation 0.35
Values 2.6 3.1
[27]
THLE GATA6
Mean 22.9
Standard deviation 5.3
Values 19 27
[28]
liver GATA6
Mean 3.48
Standard deviation 1.1
Values 3.3 3.5 2.2 4.9
[29]
ref_hepatocyte DKK1
Mean 2
Standard deviation 4.1
Values 9.3 0.59 0 0 0.089
[30]
HepG2 DKK1
Mean 172
Standard deviation 31
Values 1.5e+02 1.9e+02
[31]
HepG2.C3A DKK1
Mean 12.2
Standard deviation 9
Values 5.8 19
[32]
HuH.7 DKK1
Mean 16.1
Standard deviation 6.9
Values 19 8.2 21
[33]
SNU475 DKK1
Mean 9.29
Standard deviation 1.1
Values 8.5 10
[34]
THLE DKK1
Mean 70.4
Standard deviation 23
Values 54 87
[35]
liver DKK1
Mean 0.0656
Standard deviation 0.079
Values 0 0.043 0.18 0.04
[36]
ref_hepatocyte NANOG
Mean 0.383
Standard deviation 0.43
Values 0.059 0.41 1.1 0 0.36
[37]
HepG2 NANOG
Mean 1.13
Standard deviation 0.18
Values 1.3 1
[38]
HepG2.C3A NANOG
Mean 0.559
Standard deviation 0.38
Values 0.29 0.83
[39]
HuH.7 NANOG
Mean 0.195
Standard deviation 0.1
Values 0.14 0.31 0.13
[40]
SNU475 NANOG
Mean 0.145
Standard deviation 0.0023
Values 0.14 0.15
[41]
THLE NANOG
Mean 0.0861
Standard deviation 0.054
Values 0.12 0.048
[42]
liver NANOG
Mean 0.513
Standard deviation 0.3
Values 0.19 0.84 0.33 0.69
[43]
ref_hepatocyte SOX2
Mean 0.178
Standard deviation 0.24
Values 0.094 0 0.58 0 0.22
[44]
HepG2 SOX2
Mean 0.078
Standard deviation 0.044
Values 0.11 0.047
[45]
HepG2.C3A SOX2
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 SOX2
Mean 0.385
Standard deviation 0.086
Values 0.29 0.42 0.45
[47]
SNU475 SOX2
Mean 2.51
Standard deviation 0.99
Values 3.2 1.8
[48]
THLE SOX2
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[49]
liver SOX2
Mean 0.00999
Standard deviation 0.012
Values 0 0.014 0.026 0
[50]
ref_hepatocyte EOMES
Mean 0.103
Standard deviation 0.16
Values 0.087 0 0 0.052 0.37
[51]
HepG2 EOMES
Mean 0.167
Standard deviation 0.00079
Values 0.17 0.17
[52]
HepG2.C3A EOMES
Mean 0.712
Standard deviation 0.37
Values 0.45 0.98
[53]
HuH.7 EOMES
Mean 0.142
Standard deviation 0.065
Values 0.2 0.071 0.16
[54]
SNU475 EOMES
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[55]
THLE EOMES
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[56]
liver EOMES
Mean 0.454
Standard deviation 0.12
Values 0.56 0.29 0.46 0.5
[57]
ref_hepatocyte CDX2
Mean 0.0104
Standard deviation 0.023
Values 0.052 0 0 0 0
[58]
HepG2 CDX2
Mean 0.152
Standard deviation 0.076
Values 0.21 0.099
[59]
HepG2.C3A CDX2
Mean 0.104
Standard deviation 0.087
Values 0.17 0.043
[60]
HuH.7 CDX2
Mean 68.9
Standard deviation 15
Values 58 86 63
[61]
SNU475 CDX2
Mean 0.0534
Standard deviation 0.0034
Values 0.051 0.056
[62]
THLE CDX2
Mean 0.0349
Standard deviation 0.034
Values 0.059 0.011
[63]
liver CDX2
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[64]
ref_hepatocyte GSC
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 GSC
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[66]
HepG2.C3A GSC
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 GSC
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 GSC
Mean 0.0249
Standard deviation 0.022
Values 0.0093 0.041
[69]
THLE GSC
Mean 0.407
Standard deviation 0.057
Values 0.37 0.45
[70]
liver GSC
Mean 0
Standard deviation 0
Values 0 0 0 0