REACTOME_POU5F1_OCT4_SOX2_NANOG_ACTIVATE_GENES_RELATED_TO_PROLIFERATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 STAT3 Signal transducer and activator of transcription 3 [1] 0.31[2] -0.01[3] -0.09[4] 0.31[5] -0.43[6] 0.50[7]
2 POU5F1 POU domain, class 5, transcription factor 1 [8] -3.83[9] -0.64[10] -3.74[11] -3.74[12] -4.03[13] -5.52[14]
3 FGF2 Fibroblast growth factor 2 [15] -6.93[16] -5.50[17] -2.16[18] 1.00[19] 2.57[20] -3.57[21]
4 SALL1 Sal-like protein 1 [22] 0.77[23] -7.43[24] 1.42[25] -4.44[26] -1.61[27] -0.26[28]
5 EPHA1 Ephrin type-A receptor 1 [29] -0.07[30] 2.41[31] -2.75[32] -6.88[33] -7.28[34] -0.26[35]
6 TDGF1 Teratocarcinoma-derived growth factor 1 [36] -1.01[37] -5.60[38] -4.76[39] -8.87[40] -8.16[41] -3.06[42]
7 DPPA4 Developmental pluripotency-associated protein 4 [43] -5.16[44] -2.59[45] -4.94[46] -4.70[47] -4.82[48] -4.67[49]
8 NR6A1 Nuclear receptor subfamily 6 group A member 1 [50] 0.92[51] 2.14[52] 2.87[53] -0.80[54] -2.53[55] -1.59[56]
9 NANOG Homeobox protein NANOG [57] 0.17[58] 0.50[59] -1.77[60] -2.20[61] -3.14[62] -1.99[63]
10 SALL4 Sal-like protein 4 [64] -0.24[65] -0.83[66] 3.94[67] -0.65[68] -0.27[69] -0.73[70]
11 SOX2 Transcription factor SOX-2 [71] -2.58[72] [73] 0.31[74] 3.01[75] -5.97[76] -6.58[77]
12 FOXD3 Forkhead box protein D3 [78] -3.57[79] [80] 0.99[81] 1.95[82] [83] [84]
13 ZIC3 Zinc finger protein ZIC 3 [85] [86] [87] [88] -2.96[89] [90] [91]
[1]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 26 25 18 46 36
[2]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 90 1e+02
[3]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 34 27
[4]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 47 65 35
[5]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 74 57
[6]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[7]
liver STAT3
Mean 227
Standard deviation 42
Values 1.9e+02 2.3e+02 2.8e+02 2e+02
[8]
ref_hepatocyte POU5F1
Mean 4.56
Standard deviation 6.9
Values 0.79 0.49 17 0.95 3.9
[9]
HepG2 POU5F1
Mean 0.837
Standard deviation 0.12
Values 0.92 0.75
[10]
HepG2.C3A POU5F1
Mean 3.02
Standard deviation 1.1
Values 3.8 2.2
[11]
HuH.7 POU5F1
Mean 0.595
Standard deviation 0.041
Values 0.58 0.64 0.56
[12]
SNU475 POU5F1
Mean 0.596
Standard deviation 0.16
Values 0.71 0.48
[13]
THLE POU5F1
Mean 0.552
Standard deviation 0.15
Values 0.66 0.45
[14]
liver POU5F1
Mean 0.532
Standard deviation 0.43
Values 0.094 0.76 0.26 1
[15]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[16]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[17]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[18]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[19]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[20]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[21]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[22]
ref_hepatocyte SALL1
Mean 3.42
Standard deviation 1.6
Values 3.2 1.2 2.9 5.5 4.4
[23]
HepG2 SALL1
Mean 15.3
Standard deviation 0.65
Values 15 16
[24]
HepG2.C3A SALL1
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[25]
HuH.7 SALL1
Mean 16
Standard deviation 5
Values 15 21 12
[26]
SNU475 SALL1
Mean 0.275
Standard deviation 0.28
Values 0.074 0.48
[27]
THLE SALL1
Mean 2.22
Standard deviation 0.46
Values 2.5 1.9
[28]
liver SALL1
Mean 15.3
Standard deviation 9.1
Values 28 7.5 11 14
[29]
ref_hepatocyte EPHA1
Mean 2.12
Standard deviation 1.5
Values 2.1 0.35 0.97 3.5 3.7
[30]
HepG2 EPHA1
Mean 5.28
Standard deviation 0.35
Values 5.5 5
[31]
HepG2.C3A EPHA1
Mean 11.6
Standard deviation 2.7
Values 13 9.7
[32]
HuH.7 EPHA1
Mean 0.546
Standard deviation 0.16
Values 0.53 0.39 0.71
[33]
SNU475 EPHA1
Mean 0.0314
Standard deviation 0.0015
Values 0.032 0.03
[34]
THLE EPHA1
Mean 0.0269
Standard deviation 0.03
Values 0.0059 0.048
[35]
liver EPHA1
Mean 9.47
Standard deviation 2.7
Values 7.1 11 7.4 13
[36]
ref_hepatocyte TDGF1
Mean 1.24
Standard deviation 1.2
Values 0.8 0.067 3.3 0.78 1.3
[37]
HepG2 TDGF1
Mean 1.6
Standard deviation 0.22
Values 1.4 1.8
[38]
HepG2.C3A TDGF1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[39]
HuH.7 TDGF1
Mean 0.0792
Standard deviation 0.049
Values 0.09 0.026 0.12
[40]
SNU475 TDGF1
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[41]
THLE TDGF1
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[42]
liver TDGF1
Mean 0.794
Standard deviation 0.53
Values 1.5 0.37 0.98 0.37
[43]
ref_hepatocyte DPPA4
Mean 1.16
Standard deviation 1.5
Values 0.36 0.44 3.8 0.052 1.2
[44]
HepG2 DPPA4
Mean 0.0844
Standard deviation 0.014
Values 0.074 0.094
[45]
HepG2.C3A DPPA4
Mean 0.199
Standard deviation 0.0078
Values 0.2 0.19
[46]
HuH.7 DPPA4
Mean 0.0657
Standard deviation 0.032
Values 0.049 0.045 0.1
[47]
SNU475 DPPA4
Mean 0.0779
Standard deviation 0.012
Values 0.07 0.086
[48]
THLE DPPA4
Mean 0.081
Standard deviation 0.0058
Values 0.077 0.085
[49]
liver DPPA4
Mean 0.243
Standard deviation 0.12
Values 0.4 0.27 0.15 0.15
[50]
ref_hepatocyte NR6A1
Mean 0.737
Standard deviation 0.74
Values 1.7 0.19 1.4 0.3 0.13
[51]
HepG2 NR6A1
Mean 3.65
Standard deviation 0.13
Values 3.6 3.7
[52]
HepG2.C3A NR6A1
Mean 3.34
Standard deviation 1.6
Values 2.2 4.5
[53]
HuH.7 NR6A1
Mean 9.34
Standard deviation 4.6
Values 13 10 4.3
[54]
SNU475 NR6A1
Mean 0.742
Standard deviation 0.026
Values 0.72 0.76
[55]
THLE NR6A1
Mean 0.253
Standard deviation 0.04
Values 0.22 0.28
[56]
liver NR6A1
Mean 1.3
Standard deviation 0.95
Values 0.49 2.2 0.46 2.1
[57]
ref_hepatocyte NANOG
Mean 0.383
Standard deviation 0.43
Values 0.059 0.41 1.1 0 0.36
[58]
HepG2 NANOG
Mean 1.13
Standard deviation 0.18
Values 1.3 1
[59]
HepG2.C3A NANOG
Mean 0.559
Standard deviation 0.38
Values 0.29 0.83
[60]
HuH.7 NANOG
Mean 0.195
Standard deviation 0.1
Values 0.14 0.31 0.13
[61]
SNU475 NANOG
Mean 0.145
Standard deviation 0.0023
Values 0.14 0.15
[62]
THLE NANOG
Mean 0.0861
Standard deviation 0.054
Values 0.12 0.048
[63]
liver NANOG
Mean 0.513
Standard deviation 0.3
Values 0.19 0.84 0.33 0.69
[64]
ref_hepatocyte SALL4
Mean 0.222
Standard deviation 0.31
Values 0 0.034 0.74 0.078 0.25
[65]
HepG2 SALL4
Mean 0.491
Standard deviation 0.25
Values 0.66 0.32
[66]
HepG2.C3A SALL4
Mean 0.128
Standard deviation 0.016
Values 0.12 0.14
[67]
HuH.7 SALL4
Mean 5.9
Standard deviation 0.89
Values 5.3 6.9 5.5
[68]
SNU475 SALL4
Mean 0.247
Standard deviation 0.14
Values 0.15 0.34
[69]
THLE SALL4
Mean 0.363
Standard deviation 0.18
Values 0.49 0.23
[70]
liver SALL4
Mean 0.714
Standard deviation 0.24
Values 0.66 0.74 0.44 1
[71]
ref_hepatocyte SOX2
Mean 0.178
Standard deviation 0.24
Values 0.094 0 0.58 0 0.22
[72]
HepG2 SOX2
Mean 0.078
Standard deviation 0.044
Values 0.11 0.047
[73]
HepG2.C3A SOX2
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 SOX2
Mean 0.385
Standard deviation 0.086
Values 0.29 0.42 0.45
[75]
SNU475 SOX2
Mean 2.51
Standard deviation 0.99
Values 3.2 1.8
[76]
THLE SOX2
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[77]
liver SOX2
Mean 0.00999
Standard deviation 0.012
Values 0 0.014 0.026 0
[78]
ref_hepatocyte FOXD3
Mean 0.026
Standard deviation 0.058
Values 0 0 0 0 0.13
[79]
HepG2 FOXD3
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[80]
HepG2.C3A FOXD3
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 FOXD3
Mean 0.0897
Standard deviation 0.011
Values 0.082 0.1 0.084
[82]
SNU475 FOXD3
Mean 0.176
Standard deviation 0.038
Values 0.15 0.2
[83]
THLE FOXD3
Mean 0
Standard deviation 0
Values 0 0
[84]
liver FOXD3
Mean 0
Standard deviation 0
Values 0 0 0 0
[85]
ref_hepatocyte ZIC3
Mean 0.0225
Standard deviation 0.024
Values 0 0.028 0.027 0 0.057
[86]
HepG2 ZIC3
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A ZIC3
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 ZIC3
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 ZIC3
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[90]
THLE ZIC3
Mean 0
Standard deviation 0
Values 0 0
[91]
liver ZIC3
Mean 0
Standard deviation 0
Values 0 0 0 0