REACTOME_POTASSIUM_CHANNELS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -0.78[1] | -0.59[2] | -1.55[3] | -2.00[4] | -2.27[5] | -1.46[6] | |
2 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [7] | 1.44[8] | 1.46[9] | 0.90[10] | 1.10[11] | 0.88[12] | -1.11[13] |
3 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [14] | -0.18[15] | -0.42[16] | -0.17[17] | -0.55[18] | -0.51[19] | -1.48[20] |
4 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.27[21] | -3.98[22] | -4.37[23] | -4.00[24] | -3.20[25] | -4.22[26] | |
5 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.33[27] | -7.25[28] | 0.61[29] | 1.69[30] | 1.77[31] | 0.61[32] | |
6 | KCNJ8 | ATP-sensitive inward rectifier potassium channel 8 | [33] | -10.98[34] | [35] | -3.22[36] | -5.64[37] | -9.54[38] | 1.07[39] |
7 | KCNK1 | Potassium channel subfamily K member 1 | [40] | -10.16[41] | [42] | [43] | -6.34[44] | -2.82[45] | -1.16[46] |
8 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [47] | 0.52[48] | 0.57[49] | 1.50[50] | 0.60[51] | 0.71[52] | 1.01[53] |
9 | ABCC9 | ATP-binding cassette sub-family C member 9 | [54] | -2.45[55] | -1.24[56] | -0.19[57] | -0.51[58] | -2.31[59] | 4.07[60] |
10 | KCNN2 | Small conductance calcium-activated potassium channel protein 2 | [61] | -5.83[62] | -3.36[63] | -2.37[64] | -6.98[65] | -7.05[66] | -0.80[67] |
11 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -7.75[68] | -7.75[69] | -7.14[70] | 2.08[71] | 3.38[72] | 2.36[73] | |
12 | KCND3 | Potassium voltage-gated channel subfamily D member 3 | [74] | -5.89[75] | [76] | [77] | [78] | -7.63[79] | 2.46[80] |
13 | KCNMB3 | Calcium-activated potassium channel subunit beta-3 | [81] | -0.01[82] | 1.84[83] | 2.14[84] | -0.34[85] | -0.87[86] | -0.07[87] |
14 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.98[88] | 1.64[89] | 2.36[90] | -2.42[91] | -1.81[92] | 0.15[93] | |
15 | KCNMA1 | Calcium-activated potassium channel subunit alpha-1 | [94] | -7.44[95] | -8.08[96] | -2.10[97] | 1.48[98] | -0.88[99] | 1.61[100] |
16 | KCNAB2 | Voltage-gated potassium channel subunit beta-2 | [101] | 3.06[102] | 4.14[103] | 1.59[104] | 0.84[105] | 2.15[106] | 1.02[107] |
17 | KCNS3 | Potassium voltage-gated channel subfamily S member 3 | [108] | -4.06[109] | [110] | -5.53[111] | -2.53[112] | -1.42[113] | 0.68[114] |
18 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.90[115] | 1.67[116] | 5.38[117] | 1.07[118] | -1.06[119] | -2.43[120] | |
19 | KCNK6 | Potassium channel subfamily K member 6 | [121] | -0.02[122] | -5.88[123] | -1.39[124] | -0.06[125] | 0.29[126] | 2.08[127] |
20 | HCN3 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 | 0.83[128] | 2.28[129] | 3.12[130] | 0.30[131] | -0.26[132] | 0.11[133] | |
21 | KCNJ5 | G protein-activated inward rectifier potassium channel 4 | [134] | -2.10[135] | -0.79[136] | -1.38[137] | -2.41[138] | -2.66[139] | -1.95[140] |
22 | KCNJ11 | ATP-sensitive inward rectifier potassium channel 11 | [141] | 0.73[142] | 0.23[143] | -0.42[144] | -1.39[145] | -2.14[146] | -0.32[147] |
23 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [148] | 0.06[149] | 0.56[150] | 1.47[151] | 2.49[152] | 5.22[153] | 4.21[154] |
24 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -5.85[155] | -6.72[156] | [157] | 2.93[158] | 2.39[159] | 2.90[160] | |
25 | KCNMB4 | Calcium-activated potassium channel subunit beta-4 | [161] | 2.58[162] | 2.59[163] | 3.49[164] | 0.91[165] | 0.00[166] | 1.07[167] |
26 | KCNG3 | Potassium voltage-gated channel subfamily G member 3 | [168] | 2.01[169] | 0.89[170] | 0.02[171] | -2.30[172] | -2.57[173] | -6.34[174] |
27 | KCNK13 | Potassium channel subfamily K member 13 | [175] | 1.34[176] | 3.37[177] | -6.67[178] | -3.77[179] | -7.58[180] | -1.34[181] |
28 | KCNC3 | Potassium voltage-gated channel subfamily C member 3 | [182] | 1.19[183] | 2.34[184] | 0.01[185] | 0.30[186] | -2.19[187] | 1.25[188] |
29 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [189] | [190] | [191] | -2.25[192] | -6.94[193] | 0.23[194] | |
30 | KCNC4 | Potassium voltage-gated channel subfamily C member 4 | [195] | 3.64[196] | 2.30[197] | 2.78[198] | -0.44[199] | 1.73[200] | 2.90[201] |
31 | KCNJ4 | Inward rectifier potassium channel 4 | [202] | 0.67[203] | 0.76[204] | 2.15[205] | -5.19[206] | -2.02[207] | -1.02[208] |
32 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.43[209] | 1.41[210] | -0.91[211] | -0.89[212] | -1.22[213] | 0.04[214] | |
33 | KCNQ1 | Potassium voltage-gated channel subfamily KQT member 1 | [215] | -0.79[216] | -0.65[217] | -2.94[218] | -4.15[219] | -3.40[220] | 1.58[221] |
34 | KCNG1 | Potassium voltage-gated channel subfamily G member 1 | [222] | -1.08[223] | [224] | [225] | 1.00[226] | 4.58[227] | -4.34[228] |
35 | KCNAB1 | Voltage-gated potassium channel subunit beta-1 | [229] | 0.23[230] | 2.78[231] | 2.59[232] | 0.16[233] | 1.68[234] | 4.58[235] |
36 | KCNA7 | Potassium voltage-gated channel subfamily A member 7 | [236] | 0.06[237] | 0.96[238] | 0.62[239] | 0.05[240] | -0.06[241] | 2.00[242] |
37 | KCNH6 | Potassium voltage-gated channel subfamily H member 6 | [243] | -1.90[244] | 0.77[245] | -1.82[246] | -3.08[247] | -1.85[248] | -1.26[249] |
38 | KCNH2 | Potassium voltage-gated channel subfamily H member 2 | [250] | 2.67[251] | -2.18[252] | 1.17[253] | 6.68[254] | -0.23[255] | -0.01[256] |
39 | KCNK3 | Potassium channel subfamily K member 3 | [257] | 3.04[258] | -2.50[259] | -5.43[260] | 2.12[261] | 0.01[262] | 4.79[263] |
40 | KCNAB3 | Voltage-gated potassium channel subunit beta-3 | [264] | 0.06[265] | 2.74[266] | 1.36[267] | 0.96[268] | 3.06[269] | 0.37[270] |
41 | KCNN4 | Intermediate conductance calcium-activated potassium channel protein 4 | 4.21[271] | 0.21[272] | 0.62[273] | 5.90[274] | 2.17[275] | 0.55[276] | |
42 | KCNMB1 | Calcium-activated potassium channel subunit beta-1 | [277] | [278] | [279] | [280] | -0.68[281] | [282] | 0.70[283] |
43 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [284] | 2.02[285] | 4.28[286] | 3.49[287] | 0.82[288] | 3.52[289] | -1.56[290] |
44 | KCND2 | Potassium voltage-gated channel subfamily D member 2 | [291] | [292] | [293] | -3.17[294] | -1.27[295] | 2.70[296] | 0.06[297] |
45 | KCNJ6 | G protein-activated inward rectifier potassium channel 2 | [298] | [299] | [300] | [301] | 0.62[302] | -5.31[303] | -2.33[304] |
46 | KCNJ15 | ATP-sensitive inward rectifier potassium channel 15 | [305] | -2.00[306] | [307] | [308] | 2.47[309] | 3.15[310] | 5.28[311] |
47 | KCNA3 | Potassium voltage-gated channel subfamily A member 3 | [312] | [313] | [314] | [315] | -3.11[316] | -2.80[317] | 3.36[318] |
48 | KCNF1 | Potassium voltage-gated channel subfamily F member 1 | [319] | 3.07[320] | -2.12[321] | [322] | -1.99[323] | -4.20[324] | [325] |
49 | GABBR1 | Gamma-aminobutyric acid type B receptor subunit 1 | [326] | 3.10[327] | 1.46[328] | 0.62[329] | 6.58[330] | 6.87[331] | 4.17[332] |
50 | KCNN3 | Small conductance calcium-activated potassium channel protein 3 | [333] | 1.81[334] | 3.34[335] | 3.48[336] | 4.17[337] | 1.72[338] | 3.67[339] |
51 | KCNJ3 | G protein-activated inward rectifier potassium channel 1 | [340] | -1.67[341] | 1.11[342] | 5.03[343] | -0.63[344] | -2.02[345] | 4.86[346] |
52 | KCNB1 | Potassium voltage-gated channel subfamily B member 1 | [347] | [348] | [349] | -0.40[350] | -3.40[351] | -1.36[352] | 6.34[353] |
53 | KCNJ14 | ATP-sensitive inward rectifier potassium channel 14 | [354] | 2.27[355] | 2.22[356] | 4.36[357] | 3.44[358] | 3.30[359] | 2.95[360] |
54 | KCNQ2 | Potassium voltage-gated channel subfamily KQT member 2 | [361] | 0.83[362] | [363] | [364] | [365] | -4.70[366] | -2.57[367] |
55 | KCNJ2 | Inward rectifier potassium channel 2 | [368] | -1.92[369] | [370] | [371] | 3.09[372] | 3.23[373] | 5.99[374] |
56 | KCND1 | Potassium voltage-gated channel subfamily D member 1 | [375] | 1.48[376] | 4.50[377] | 3.82[378] | 6.28[379] | 4.81[380] | 3.27[381] |
57 | KCNK2 | Potassium channel subfamily K member 2 | [382] | -2.60[383] | [384] | -3.50[385] | -0.87[386] | 4.03[387] | [388] |
58 | KCNK17 | Potassium channel subfamily K member 17 | [389] | [390] | [391] | [392] | [393] | [394] | 3.91[395] |
59 | KCNJ10 | ATP-sensitive inward rectifier potassium channel 10 | [396] | 8.60[397] | 1.73[398] | 0.65[399] | 2.25[400] | 0.69[401] | 4.76[402] |
60 | KCNJ16 | Inward rectifier potassium channel 16 | [403] | [404] | [405] | -1.26[406] | 2.67[407] | 0.69[408] | 5.83[409] |
61 | KCNMB2 | Calcium-activated potassium channel subunit beta-2 | [410] | [411] | 0.89[412] | 1.98[413] | -1.45[414] | -2.46[415] | 1.14[416] |
62 | ABCC8 | ATP-binding cassette sub-family C member 8 | [417] | -0.47[418] | [419] | -1.48[420] | [421] | [422] | 1.61[423] |
63 | KCNN1 | Small conductance calcium-activated potassium channel protein 1 | [424] | 4.39[425] | -0.77[426] | 0.10[427] | 1.31[428] | 4.97[429] | -0.69[430] |
64 | KCNS1 | Potassium voltage-gated channel subfamily S member 1 | [431] | -0.55[432] | [433] | -0.64[434] | 5.16[435] | 4.97[436] | 3.05[437] |
65 | KCNH5 | Potassium voltage-gated channel subfamily H member 5 | [438] | [439] | [440] | [441] | 1.88[442] | 0.90[443] | [444] |
66 | KCNQ4 | Potassium voltage-gated channel subfamily KQT member 4 | [445] | 0.45[446] | 2.89[447] | 4.55[448] | 1.18[449] | 1.15[450] | 3.12[451] |
67 | HCN1 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | 1.32[452] | 0.61[453] | 1.97[454] | [455] | -1.44[456] | 2.89[457] | |
68 | KCNQ3 | Potassium voltage-gated channel subfamily KQT member 3 | [458] | 1.16[459] | [460] | [461] | 4.06[462] | 5.34[463] | 2.03[464] |
69 | HCN4 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 2.86[465] | -0.90[466] | 4.50[467] | -0.86[468] | 4.48[469] | 1.04[470] | |
70 | KCNH3 | Potassium voltage-gated channel subfamily H member 3 | [471] | 6.61[472] | 6.13[473] | 1.47[474] | 3.06[475] | 4.68[476] | 4.83[477] |
71 | GABBR2 | Gamma-aminobutyric acid type B receptor subunit 2 | [478] | 3.77[479] | 1.77[480] | 2.82[481] | 1.95[482] | 6.25[483] | 4.56[484] |
72 | HCN2 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | 6.76[485] | 4.46[486] | 8.24[487] | 7.01[488] | 6.61[489] | 2.27[490] | |
73 | KCNA6 | Potassium voltage-gated channel subfamily A member 6 | [491] | -0.03[492] | [493] | -0.17[494] | -1.01[495] | [496] | 3.13[497] |
74 | KCNH1 | Potassium voltage-gated channel subfamily H member 1 | [498] | 4.07[499] | 2.66[500] | [501] | 5.34[502] | 1.26[503] | 5.20[504] |
75 | KCNJ12 | ATP-sensitive inward rectifier potassium channel 12 | [505] | [506] | [507] | 0.18[508] | 7.59[509] | 6.92[510] | 5.55[511] |
76 | KCNA5 | Potassium voltage-gated channel subfamily A member 5 | [512] | [513] | [514] | [515] | [516] | [517] | [518] |
77 | KCNJ1 | ATP-sensitive inward rectifier potassium channel 1 | [519] | [520] | [521] | [522] | [523] | [524] | [525] |
78 | KCNK18 | Potassium channel subfamily K member 18 | [526] | [527] | [528] | [529] | [530] | [531] | [532] |
79 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [533] | [534] | [535] | [536] | [537] | [538] | |
80 | KCNK16 | Potassium channel subfamily K member 16 | [539] | [540] | [541] | [542] | [543] | [544] | [545] |
81 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [546] | [547] | [548] | [549] | [550] | [551] | |
82 | KCNJ9 | G protein-activated inward rectifier potassium channel 3 | [552] | [553] | [554] | [555] | [556] | [557] | [558] |
83 | KCNA1 | Potassium voltage-gated channel subfamily A member 1 | [559] | [560] | [561] | [562] | [563] | [564] | [565] |
84 | KCNG2 | Potassium voltage-gated channel subfamily G member 2 | [566] | [567] | [568] | [569] | [570] | [571] | [572] |
85 | KCNK9 | Potassium channel subfamily K member 9 | [573] | [574] | [575] | [576] | [577] | [578] | [579] |
86 | KCNA10 | Potassium voltage-gated channel subfamily A member 10 | [580] | [581] | [582] | [583] | [584] | [585] | [586] |
87 | KCNA2 | Potassium voltage-gated channel subfamily A member 2 | [587] | [588] | [589] | [590] | [591] | [592] | [593] |
88 | KCNK10 | Potassium channel subfamily K member 10 | [594] | [595] | [596] | [597] | [598] | [599] | [600] |
89 | KCNV2 | Potassium voltage-gated channel subfamily V member 2 | [601] | [602] | [603] | [604] | [605] | [606] | [607] |
90 | KCNG4 | Potassium voltage-gated channel subfamily G member 4 | [608] | [609] | [610] | [611] | [612] | [613] | [614] |
91 | KCNC2 | Potassium voltage-gated channel subfamily C member 2 | [615] | [616] | [617] | [618] | [619] | [620] | [621] |
92 | KCNK4 | Potassium channel subfamily K member 4 | [622] | [623] | [624] | [625] | [626] | [627] | [628] |
93 | KCNB2 | Potassium voltage-gated channel subfamily B member 2 | [629] | [630] | [631] | [632] | [633] | [634] | [635] |
94 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [636] | [637] | [638] | [639] | [640] | [641] | [642] |
95 | KCNH7 | Potassium voltage-gated channel subfamily H member 7 | [643] | [644] | [645] | [646] | [647] | [648] | [649] |
96 | KCNV1 | Potassium voltage-gated channel subfamily V member 1 | [650] | [651] | [652] | [653] | [654] | [655] | [656] |
97 | KCNS2 | Potassium voltage-gated channel subfamily S member 2 | [657] | [658] | [659] | [660] | [661] | [662] | [663] |
98 | KCNA4 | Potassium voltage-gated channel subfamily A member 4 | [664] | [665] | [666] | [667] | [668] | [669] | [670] |
99 | KCNC1 | Potassium voltage-gated channel subfamily C member 1 | [671] | [672] | [673] | [674] | [675] | [676] | [677] |
100 | KCNK7 | Potassium channel subfamily K member 7 | [678] | [679] | [680] | [681] | [682] | [683] | [684] |
101 | KCNH8 | Potassium voltage-gated channel subfamily H member 8 | [685] | [686] | [687] | [688] | [689] | [690] | [691] |
102 | KCNH4 | Potassium voltage-gated channel subfamily H member 4 | [692] | [693] | [694] | [695] | [696] | [697] | [698] |
103 | KCNQ5 | Potassium voltage-gated channel subfamily KQT member 5 | [699] | [700] | [701] | [702] | [703] | [704] | [705] |