REACTOME_POLYMERASE_SWITCHING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PCNA Proliferating cell nuclear antigen [1] 0.78[2] 0.51[3] -1.03[4] -0.75[5] -0.29[6] -2.45[7]
2 POLD2 DNA polymerase delta subunit 2 [8] -0.70[9] -0.79[10] -0.40[11] -1.40[12] -0.85[13] 0.50[14]
3 POLD4 DNA polymerase delta subunit 4 [15] -2.23[16] -2.84[17] -0.88[18] 0.91[19] -2.50[20] 0.14[21]
4 RFC4 Replication factor C subunit 4 [22] -1.07[23] -0.70[24] -0.25[25] -1.50[26] 0.01[27] -2.13[28]
5 RFC1 Replication factor C subunit 1 [29] 0.04[30] 1.07[31] 1.32[32] -0.21[33] 0.81[34] 1.40[35]
6 RFC2 Replication factor C subunit 2 [36] -0.37[37] -0.77[38] -0.85[39] -0.35[40] 0.28[41] -0.15[42]
7 RFC5 Replication factor C subunit 5 [43] 0.02[44] 0.23[45] 0.30[46] -0.27[47] 0.44[48] -0.26[49]
8 RFC3 Replication factor C subunit 3 [50] 1.07[51] 1.68[52] 1.69[53] 0.72[54] 1.49[55] -0.25[56]
9 POLA2 DNA polymerase alpha subunit B [57] 0.54[58] -0.09[59] 0.35[60] 0.99[61] 1.46[62] -0.22[63]
10 PRIM1 DNA primase small subunit [64] 0.56[65] 1.63[66] 1.84[67] 0.63[68] 1.39[69] -0.29[70]
11 POLD1 DNA polymerase delta catalytic subunit [71] 1.75[72] 1.72[73] 2.41[74] 1.29[75] 2.23[76] 1.29[77]
12 PRIM2 DNA primase large subunit [78] 1.17[79] 0.72[80] 0.21[81] 0.65[82] 1.07[83] -0.96[84]
13 POLD3 DNA polymerase delta subunit 3 [85] 1.07[86] 0.68[87] 1.53[88] 1.58[89] 2.25[90] 1.61[91]
14 POLA1 DNA polymerase alpha catalytic subunit [92] 1.90[93] 1.76[94] 2.19[95] 2.46[96] 2.60[97] 2.29[98]
[1]
ref_hepatocyte PCNA
Mean 36
Standard deviation 33
Values 92 37 14 19 17
[2]
HepG2 PCNA
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[3]
HepG2.C3A PCNA
Mean 130
Standard deviation 86
Values 69 1.9e+02
[4]
HuH.7 PCNA
Mean 46.8
Standard deviation 33
Values 53 10 76
[5]
SNU475 PCNA
Mean 56.8
Standard deviation 7.7
Values 51 62
[6]
THLE PCNA
Mean 77.4
Standard deviation 13
Values 68 86
[7]
liver PCNA
Mean 6.07
Standard deviation 2.5
Values 7.3 5.2 8.8 3
[8]
ref_hepatocyte POLD2
Mean 32.3
Standard deviation 18
Values 10 23 30 58 40
[9]
HepG2 POLD2
Mean 47
Standard deviation 5.6
Values 51 43
[10]
HepG2.C3A POLD2
Mean 47.2
Standard deviation 5.4
Values 43 51
[11]
HuH.7 POLD2
Mean 64.5
Standard deviation 25
Values 79 36 79
[12]
SNU475 POLD2
Mean 32.5
Standard deviation 4.3
Values 29 35
[13]
THLE POLD2
Mean 47.1
Standard deviation 7.9
Values 41 53
[14]
liver POLD2
Mean 42.1
Standard deviation 24
Values 67 21 57 23
[15]
ref_hepatocyte POLD4
Mean 31.5
Standard deviation 27
Values 1.6 16 19 64 57
[16]
HepG2 POLD4
Mean 15.9
Standard deviation 3.9
Values 19 13
[17]
HepG2.C3A POLD4
Mean 11.1
Standard deviation 4
Values 14 8.3
[18]
HuH.7 POLD4
Mean 45.1
Standard deviation 6.1
Values 39 51 46
[19]
SNU475 POLD4
Mean 157
Standard deviation 53
Values 1.9e+02 1.2e+02
[20]
THLE POLD4
Mean 14.6
Standard deviation 1.8
Values 13 16
[21]
liver POLD4
Mean 32.1
Standard deviation 32
Values 48 6 69 5.3
[22]
ref_hepatocyte RFC4
Mean 11
Standard deviation 7.9
Values 17 21 9.8 4.7 2.4
[23]
HepG2 RFC4
Mean 12.4
Standard deviation 2.7
Values 10 14
[24]
HepG2.C3A RFC4
Mean 17
Standard deviation 7.7
Values 12 22
[25]
HuH.7 RFC4
Mean 24.4
Standard deviation 12
Values 26 12 35
[26]
SNU475 RFC4
Mean 10.3
Standard deviation 3.5
Values 7.8 13
[27]
THLE RFC4
Mean 29.1
Standard deviation 0.079
Values 29 29
[28]
liver RFC4
Mean 2.31
Standard deviation 1.2
Values 2.3 1.9 4 1
[29]
ref_hepatocyte RFC1
Mean 9.26
Standard deviation 5.4
Values 15 15 7.1 4.1 5
[30]
HepG2 RFC1
Mean 22.5
Standard deviation 11
Values 15 30
[31]
HepG2.C3A RFC1
Mean 49.1
Standard deviation 4.6
Values 46 52
[32]
HuH.7 RFC1
Mean 61.4
Standard deviation 8.8
Values 66 67 51
[33]
SNU475 RFC1
Mean 21.2
Standard deviation 2
Values 20 23
[34]
THLE RFC1
Mean 42.7
Standard deviation 3.9
Values 45 40
[35]
liver RFC1
Mean 22.6
Standard deviation 3.4
Values 24 26 18 23
[36]
ref_hepatocyte RFC2
Mean 8.95
Standard deviation 3.2
Values 7.3 13 6.2 11 6.5
[37]
HepG2 RFC2
Mean 16.5
Standard deviation 2.8
Values 14 18
[38]
HepG2.C3A RFC2
Mean 13.3
Standard deviation 5.7
Values 9.3 17
[39]
HuH.7 RFC2
Mean 13.1
Standard deviation 6.2
Values 15 6.1 18
[40]
SNU475 RFC2
Mean 18.6
Standard deviation 4.4
Values 16 22
[41]
THLE RFC2
Mean 28.7
Standard deviation 3.4
Values 26 31
[42]
liver RFC2
Mean 7.44
Standard deviation 4.1
Values 10 4.9 11 3.1
[43]
ref_hepatocyte RFC5
Mean 5.54
Standard deviation 4.9
Values 13 7.4 0.42 3.6 3.2
[44]
HepG2 RFC5
Mean 13.4
Standard deviation 5.4
Values 9.6 17
[45]
HepG2.C3A RFC5
Mean 16.4
Standard deviation 10
Values 9 24
[46]
HuH.7 RFC5
Mean 18.1
Standard deviation 6.8
Values 23 10 21
[47]
SNU475 RFC5
Mean 12.2
Standard deviation 2.4
Values 11 14
[48]
THLE RFC5
Mean 19.8
Standard deviation 2.4
Values 18 22
[49]
liver RFC5
Mean 4.29
Standard deviation 1.7
Values 4.9 3.5 6.3 2.5
[50]
ref_hepatocyte RFC3
Mean 3.17
Standard deviation 3.1
Values 6.3 6.7 1.4 0.35 1.1
[51]
HepG2 RFC3
Mean 15.8
Standard deviation 7.8
Values 10 21
[52]
HepG2.C3A RFC3
Mean 25.6
Standard deviation 17
Values 14 37
[53]
HuH.7 RFC3
Mean 27.1
Standard deviation 12
Values 35 14 33
[54]
SNU475 RFC3
Mean 13.8
Standard deviation 3.5
Values 11 16
[55]
THLE RFC3
Mean 23.5
Standard deviation 5.4
Values 20 27
[56]
liver RFC3
Mean 2.46
Standard deviation 0.85
Values 2 2.9 3.4 1.5
[57]
ref_hepatocyte POLA2
Mean 2.46
Standard deviation 0.96
Values 1.8 2.8 3.9 2.3 1.5
[58]
HepG2 POLA2
Mean 8.49
Standard deviation 2.2
Values 6.9 10
[59]
HepG2.C3A POLA2
Mean 5.87
Standard deviation 3.6
Values 3.3 8.4
[60]
HuH.7 POLA2
Mean 8.32
Standard deviation 5.1
Values 11 2.5 11
[61]
SNU475 POLA2
Mean 12.9
Standard deviation 3.1
Values 11 15
[62]
THLE POLA2
Mean 17.9
Standard deviation 4
Values 15 21
[63]
liver POLA2
Mean 1.96
Standard deviation 0.6
Values 1.2 1.9 2.6 2.2
[64]
ref_hepatocyte PRIM1
Mean 2.43
Standard deviation 1.4
Values 4.4 2.6 0.57 2.6 1.9
[65]
HepG2 PRIM1
Mean 8.54
Standard deviation 0.87
Values 7.9 9.2
[66]
HepG2.C3A PRIM1
Mean 19.1
Standard deviation 8.1
Values 13 25
[67]
HuH.7 PRIM1
Mean 23.1
Standard deviation 6.2
Values 27 16 26
[68]
SNU475 PRIM1
Mean 9.98
Standard deviation 3.1
Values 7.8 12
[69]
THLE PRIM1
Mean 16.8
Standard deviation 2.1
Values 15 18
[70]
liver PRIM1
Mean 1.84
Standard deviation 0.34
Values 2.1 1.6 2.1 1.5
[71]
ref_hepatocyte POLD1
Mean 2.41
Standard deviation 0.8
Values 2 3.5 2.7 2.4 1.4
[72]
HepG2 POLD1
Mean 19.3
Standard deviation 1.9
Values 21 18
[73]
HepG2.C3A POLD1
Mean 20.1
Standard deviation 2.3
Values 18 22
[74]
HuH.7 POLD1
Mean 34
Standard deviation 15
Values 42 16 44
[75]
SNU475 POLD1
Mean 15.6
Standard deviation 2.9
Values 14 18
[76]
THLE POLD1
Mean 29.7
Standard deviation 2.6
Values 28 32
[77]
liver POLD1
Mean 5.43
Standard deviation 0.68
Values 6.2 4.7 5.8 5.1
[78]
ref_hepatocyte PRIM2
Mean 2.32
Standard deviation 2.3
Values 6.1 2.9 0.46 1.4 0.78
[79]
HepG2 PRIM2
Mean 12.4
Standard deviation 3.6
Values 9.9 15
[80]
HepG2.C3A PRIM2
Mean 9.66
Standard deviation 4.4
Values 6.5 13
[81]
HuH.7 PRIM2
Mean 7.1
Standard deviation 1.5
Values 7.8 5.4 8.1
[82]
SNU475 PRIM2
Mean 9.65
Standard deviation 1.6
Values 8.5 11
[83]
THLE PRIM2
Mean 12.8
Standard deviation 1.5
Values 12 14
[84]
liver PRIM2
Mean 1.1
Standard deviation 0.41
Values 0.68 1.5 0.82 1.4
[85]
ref_hepatocyte POLD3
Mean 1.46
Standard deviation 0.56
Values 1.9 1.9 1 1.8 0.71
[86]
HepG2 POLD3
Mean 7.29
Standard deviation 0.95
Values 6.6 8
[87]
HepG2.C3A POLD3
Mean 5.94
Standard deviation 4
Values 3.1 8.8
[88]
HuH.7 POLD3
Mean 11.2
Standard deviation 6.1
Values 15 4.1 14
[89]
SNU475 POLD3
Mean 11.6
Standard deviation 3.7
Values 9 14
[90]
THLE POLD3
Mean 18.3
Standard deviation 1.6
Values 17 19
[91]
liver POLD3
Mean 4.11
Standard deviation 1.1
Values 3.6 4.3 5.6 3
[92]
ref_hepatocyte POLA1
Mean 0.985
Standard deviation 0.81
Values 1.8 2 0.27 0.52 0.41
[93]
HepG2 POLA1
Mean 8.75
Standard deviation 4.7
Values 5.4 12
[94]
HepG2.C3A POLA1
Mean 8.42
Standard deviation 3.5
Values 5.9 11
[95]
HuH.7 POLA1
Mean 11.9
Standard deviation 5.3
Values 17 6.3 13
[96]
SNU475 POLA1
Mean 14.3
Standard deviation 5.6
Values 10 18
[97]
THLE POLA1
Mean 15.7
Standard deviation 1.1
Values 15 17
[98]
liver POLA1
Mean 4.45
Standard deviation 2.4
Values 1.9 7.6 3.5 4.8