REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CCNB1 G2/mitotic-specific cyclin-B1 [1] -0.08[2] -0.09[3] -0.01[4] -0.26[5] 0.19[6] -2.52[7]
2 RBBP4 Histone-binding protein RBBP4 [8] 0.02[9] -0.12[10] -0.40[11] -0.19[12] -0.33[13] 1.33[14]
3 LIN37 Protein lin-37 homolog [15] -3.93[16] -3.74[17] -3.52[18] -3.53[19] -3.81[20] -1.89[21]
4 PLK1 Serine/threonine-protein kinase PLK1 [22] 0.57[23] 0.06[24] -0.18[25] -0.62[26] -0.11[27] -2.80[28]
5 MYBL2 Myb-related protein B [29] 1.08[30] 0.28[31] -0.28[32] 1.02[33] 0.10[34] -2.97[35]
6 WEE1 Wee1-like protein kinase [36] -1.62[37] -1.45[38] -0.81[39] -1.14[40] -2.15[41] -0.71[42]
7 LIN52 Protein lin-52 homolog [43] -1.95[44] -1.44[45] -2.09[46] -2.97[47] -2.38[48] -0.52[49]
8 EP300 Histone acetyltransferase p300 [50] 0.80[51] 0.14[52] 0.94[53] 0.71[54] 0.23[55] 2.58[56]
9 CDC25A M-phase inducer phosphatase 1 [57] -0.50[58] -0.11[59] 0.14[60] -1.52[61] -0.59[62] -2.83[63]
10 CCNB2 G2/mitotic-specific cyclin-B2 [64] 0.17[65] 0.68[66] 0.96[67] 0.66[68] 1.11[69] -1.77[70]
11 PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase -0.61[71] -1.08[72] -1.04[73] -1.22[74] -0.56[75] -2.73[76]
12 FOXM1 Forkhead box protein M1 [77] 1.30[78] 0.95[79] 1.65[80] 1.04[81] 2.03[82] -0.78[83]
13 LIN54 Protein lin-54 homolog [84] -0.49[85] 0.77[86] -0.36[87] -0.76[88] -0.43[89] 1.63[90]
14 CENPF Centromere protein F [91] 0.65[92] 3.05[93] 2.79[94] 3.18[95] 2.89[96] 1.27[97]
15 CDC25C M-phase inducer phosphatase 3 [98] 0.01[99] 0.91[100] 0.85[101] 0.06[102] 0.38[103] -1.59[104]
16 LIN9 Protein lin-9 homolog [105] -0.90[106] 0.17[107] 0.80[108] 1.03[109] 0.00[110] -0.18[111]
[1]
ref_hepatocyte CCNB1
Mean 8.2
Standard deviation 8.6
Values 15 20 1.8 3.1 1.3
[2]
HepG2 CCNB1
Mean 65.1
Standard deviation 21
Values 50 80
[3]
HepG2.C3A CCNB1
Mean 68.3
Standard deviation 39
Values 41 96
[4]
HuH.7 CCNB1
Mean 74.2
Standard deviation 37
Values 87 33 1e+02
[5]
SNU475 CCNB1
Mean 45.8
Standard deviation 3.3
Values 48 44
[6]
THLE CCNB1
Mean 101
Standard deviation 30
Values 80 1.2e+02
[7]
liver CCNB1
Mean 2.29
Standard deviation 1.6
Values 2.3 2.4 4.2 0.28
[8]
ref_hepatocyte RBBP4
Mean 7.41
Standard deviation 4.4
Values 15 5.5 3.7 7.2 5.6
[9]
HepG2 RBBP4
Mean 62.8
Standard deviation 14
Values 53 73
[10]
HepG2.C3A RBBP4
Mean 60.7
Standard deviation 2
Values 59 62
[11]
HuH.7 RBBP4
Mean 51.2
Standard deviation 12
Values 58 38 58
[12]
SNU475 RBBP4
Mean 43.5
Standard deviation 3.5
Values 46 41
[13]
THLE RBBP4
Mean 63.8
Standard deviation 8.4
Values 58 70
[14]
liver RBBP4
Mean 29.8
Standard deviation 6
Values 24 30 38 27
[15]
ref_hepatocyte LIN37
Mean 5.39
Standard deviation 4.7
Values 1.7 4.1 13 5.4 2.4
[16]
HepG2 LIN37
Mean 2.96
Standard deviation 0.14
Values 3.1 2.9
[17]
HepG2.C3A LIN37
Mean 3.59
Standard deviation 1.1
Values 4.3 2.8
[18]
HuH.7 LIN37
Mean 4.28
Standard deviation 0.46
Values 4.4 3.8 4.7
[19]
SNU475 LIN37
Mean 3.12
Standard deviation 0.33
Values 2.9 3.4
[20]
THLE LIN37
Mean 4.15
Standard deviation 0.017
Values 4.1 4.2
[21]
liver LIN37
Mean 2.33
Standard deviation 2
Values 4.7 0.53 3.3 0.79
[22]
ref_hepatocyte PLK1
Mean 4.92
Standard deviation 5.9
Values 13 9.1 0.65 1.1 0.48
[23]
HepG2 PLK1
Mean 61.1
Standard deviation 5.4
Values 57 65
[24]
HepG2.C3A PLK1
Mean 45.5
Standard deviation 17
Values 33 58
[25]
HuH.7 PLK1
Mean 39.6
Standard deviation 20
Values 55 17 47
[26]
SNU475 PLK1
Mean 21.4
Standard deviation 1.4
Values 20 22
[27]
THLE PLK1
Mean 49.2
Standard deviation 23
Values 33 65
[28]
liver PLK1
Mean 1.13
Standard deviation 1.1
Values 1.2 0.53 2.7 0.093
[29]
ref_hepatocyte MYBL2
Mean 4.89
Standard deviation 5.4
Values 11 10 1.5 0.52 0.85
[30]
HepG2 MYBL2
Mean 86.3
Standard deviation 1.1
Values 86 87
[31]
HepG2.C3A MYBL2
Mean 52.6
Standard deviation 30
Values 31 74
[32]
HuH.7 MYBL2
Mean 36.6
Standard deviation 23
Values 54 10 46
[33]
SNU475 MYBL2
Mean 66.5
Standard deviation 0.61
Values 67 66
[34]
THLE MYBL2
Mean 56.9
Standard deviation 2.3
Values 55 58
[35]
liver MYBL2
Mean 1
Standard deviation 0.86
Values 2 0.61 1.4 0.026
[36]
ref_hepatocyte WEE1
Mean 4.87
Standard deviation 1.2
Values 5.1 4.1 6.8 3.9 4.5
[37]
HepG2 WEE1
Mean 13.3
Standard deviation 1.3
Values 14 12
[38]
HepG2.C3A WEE1
Mean 15.8
Standard deviation 0.28
Values 16 16
[39]
HuH.7 WEE1
Mean 25.2
Standard deviation 0.7
Values 24 26 26
[40]
SNU475 WEE1
Mean 14.8
Standard deviation 0.86
Values 15 14
[41]
THLE WEE1
Mean 11.9
Standard deviation 1.6
Values 11 13
[42]
liver WEE1
Mean 4.76
Standard deviation 1.4
Values 6.8 4.4 3.8 4
[43]
ref_hepatocyte LIN52
Mean 2.62
Standard deviation 1.5
Values 3.9 1.9 4.7 1.4 1.2
[44]
HepG2 LIN52
Mean 5.68
Standard deviation 1.2
Values 4.8 6.6
[45]
HepG2.C3A LIN52
Mean 8.55
Standard deviation 4.3
Values 5.5 12
[46]
HuH.7 LIN52
Mean 5.62
Standard deviation 0.72
Values 6.1 4.8 6
[47]
SNU475 LIN52
Mean 2.24
Standard deviation 0.051
Values 2.3 2.2
[48]
THLE LIN52
Mean 5.44
Standard deviation 0.89
Values 4.8 6.1
[49]
liver LIN52
Mean 2.93
Standard deviation 0.97
Values 2.3 3.1 4.2 2.1
[50]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[51]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[52]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[53]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[54]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[55]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[56]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[57]
ref_hepatocyte CDC25A
Mean 2.04
Standard deviation 2.5
Values 6.2 2.3 1 0.26 0.37
[58]
HepG2 CDC25A
Mean 12.1
Standard deviation 2.6
Values 10 14
[59]
HepG2.C3A CDC25A
Mean 16.8
Standard deviation 9.8
Values 9.8 24
[60]
HuH.7 CDC25A
Mean 20.5
Standard deviation 10
Values 26 8.6 27
[61]
SNU475 CDC25A
Mean 4.76
Standard deviation 2.1
Values 3.3 6.2
[62]
THLE CDC25A
Mean 14.6
Standard deviation 2.2
Values 13 16
[63]
liver CDC25A
Mean 0.459
Standard deviation 0.38
Values 0.33 1 0.28 0.2
[64]
ref_hepatocyte CCNB2
Mean 1.97
Standard deviation 1.8
Values 4.5 3.3 0.37 1.1 0.63
[65]
HepG2 CCNB2
Mean 18.6
Standard deviation 2.7
Values 17 20
[66]
HepG2.C3A CCNB2
Mean 28
Standard deviation 11
Values 20 36
[67]
HuH.7 CCNB2
Mean 35
Standard deviation 14
Values 40 19 46
[68]
SNU475 CCNB2
Mean 20.8
Standard deviation 0.15
Values 21 21
[69]
THLE CCNB2
Mean 46.1
Standard deviation 8.4
Values 40 52
[70]
liver CCNB2
Mean 0.924
Standard deviation 0.76
Values 1 0.61 1.9 0.15
[71]
ref_hepatocyte PKMYT1
Mean 1.79
Standard deviation 1.3
Values 3 3.3 0.73 0.99 0.91
[72]
HepG2 PKMYT1
Mean 9.81
Standard deviation 0.77
Values 10 9.3
[73]
HepG2.C3A PKMYT1
Mean 7.51
Standard deviation 2.2
Values 6 9.1
[74]
HuH.7 PKMYT1
Mean 7.9
Standard deviation 5.1
Values 11 2 11
[75]
SNU475 PKMYT1
Mean 5.13
Standard deviation 2.1
Values 3.6 6.6
[76]
THLE PKMYT1
Mean 13.1
Standard deviation 1.4
Values 12 14
[77]
liver PKMYT1
Mean 0.433
Standard deviation 0.38
Values 0.38 0.3 0.98 0.079
[78]
ref_hepatocyte FOXM1
Mean 1.44
Standard deviation 0.69
Values 2.4 1.9 1.2 1.2 0.55
[79]
HepG2 FOXM1
Mean 29.8
Standard deviation 8.6
Values 24 36
[80]
HepG2.C3A FOXM1
Mean 24.7
Standard deviation 10
Values 18 32
[81]
HuH.7 FOXM1
Mean 41.2
Standard deviation 21
Values 59 19 46
[82]
SNU475 FOXM1
Mean 19.9
Standard deviation 1.7
Values 19 21
[83]
THLE FOXM1
Mean 63.7
Standard deviation 17
Values 52 76
[84]
liver FOXM1
Mean 1.34
Standard deviation 1
Values 1.2 0.97 2.8 0.46
[85]
ref_hepatocyte LIN54
Mean 1.42
Standard deviation 0.64
Values 2.3 1.7 0.89 0.74 1.4
[86]
HepG2 LIN54
Mean 8.41
Standard deviation 4.8
Values 5 12
[87]
HepG2.C3A LIN54
Mean 21.5
Standard deviation 4.2
Values 18 24
[88]
HuH.7 LIN54
Mean 10
Standard deviation 0.65
Values 11 10 9.3
[89]
SNU475 LIN54
Mean 5.61
Standard deviation 0.82
Values 5 6.2
[90]
THLE LIN54
Mean 11.4
Standard deviation 1.1
Values 11 12
[91]
liver LIN54
Mean 7.02
Standard deviation 1.6
Values 4.8 8.7 6.9 7.7
[92]
ref_hepatocyte CENPF
Mean 0.851
Standard deviation 0.9
Values 2.1 1.5 0.17 0.23 0.25
[93]
HepG2 CENPF
Mean 11.2
Standard deviation 3.8
Values 8.5 14
[94]
HepG2.C3A CENPF
Mean 62.3
Standard deviation 30
Values 41 84
[95]
HuH.7 CENPF
Mean 53.7
Standard deviation 26
Values 79 27 55
[96]
SNU475 CENPF
Mean 51.7
Standard deviation 12
Values 43 60
[97]
THLE CENPF
Mean 68.2
Standard deviation 22
Values 84 53
[98]
liver CENPF
Mean 3.28
Standard deviation 2.9
Values 1.9 7.1 3.9 0.26
[99]
ref_hepatocyte CDC25C
Mean 0.731
Standard deviation 0.89
Values 2 1.3 0.11 0.078 0.13
[100]
HepG2 CDC25C
Mean 6.16
Standard deviation 0.58
Values 5.7 6.6
[101]
HepG2.C3A CDC25C
Mean 12.2
Standard deviation 6.2
Values 7.8 17
[102]
HuH.7 CDC25C
Mean 12
Standard deviation 5.4
Values 14 5.9 16
[103]
SNU475 CDC25C
Mean 5.11
Standard deviation 0.28
Values 5.3 4.9
[104]
THLE CDC25C
Mean 10.3
Standard deviation 1.8
Values 9 12
[105]
liver CDC25C
Mean 0.389
Standard deviation 0.27
Values 0.45 0.43 0.67 0.013
[106]
ref_hepatocyte LIN9
Mean 0.607
Standard deviation 0.55
Values 1.4 0.95 0.2 0.16 0.31
[107]
HepG2 LIN9
Mean 2.71
Standard deviation 1.1
Values 1.9 3.5
[108]
HepG2.C3A LIN9
Mean 6.07
Standard deviation 4.2
Values 3.1 9.1
[109]
HuH.7 LIN9
Mean 9.59
Standard deviation 2.4
Values 11 6.8 11
[110]
SNU475 LIN9
Mean 8.31
Standard deviation 1.7
Values 7.1 9.5
[111]
THLE LIN9
Mean 6.58
Standard deviation 0.93
Values 7.2 5.9
[112]
liver LIN9
Mean 0.855
Standard deviation 0.079
Values 0.87 0.88 0.92 0.74