REACTOME_PLATELET_SENSITIZATION_BY_LDL Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOB Apolipoprotein B-100 [1] 0.60[2] 0.75[3] 0.59[4] -7.22[5] -7.09[6] 0.95[7]
2 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform -0.54[8] -1.33[9] -0.75[10] 1.43[11] 0.83[12] -3.77[13]
3 PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform -1.07[14] -1.59[15] -1.57[16] 0.97[17] 1.15[18] -4.01[19]
4 PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform -1.73[20] -2.69[21] -1.96[22] -0.23[23] -0.26[24] -4.90[25]
5 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [26] -0.89[27] -1.08[28] -0.47[29] 1.11[30] 1.82[31] -2.65[32]
6 PPP2R5A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform -2.46[33] -2.19[34] -0.81[35] -0.03[36] -1.08[37] -3.27[38]
7 PPP2R5C Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform -1.65[39] -1.39[40] -1.03[41] 1.16[42] 1.04[43] -4.11[44]
8 PPP2R1B Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform -0.89[45] -2.03[46] -0.96[47] 0.49[48] 0.35[49] -0.98[50]
9 MAPK14 Mitogen-activated protein kinase 14 [51] 0.13[52] -0.42[53] -0.19[54] 1.91[55] 1.45[56] -2.63[57]
10 PPP2R5D Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform -0.09[58] -0.95[59] -0.74[60] 1.51[61] 1.47[62] -4.18[63]
11 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform -1.23[64] -1.67[65] -1.48[66] 1.08[67] 0.94[68] -3.72[69]
12 PTPN6 Tyrosine-protein phosphatase non-receptor type 6 [70] -1.80[71] -2.23[72] -1.00[73] -6.92[74] -1.82[75] -4.09[76]
13 PPP2R5B Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform -0.56[77] -1.42[78] -1.41[79] 0.51[80] 1.75[81] -3.82[82]
14 FGR Tyrosine-protein kinase Fgr [83] [84] [85] -8.18[86] -4.45[87] -7.22[88] -2.22[89]
15 LRP8 Low-density lipoprotein receptor-related protein 8 [90] 1.09[91] 1.23[92] 2.26[93] 3.73[94] 3.73[95] -5.95[96]
16 PECAM1 Platelet endothelial cell adhesion molecule [97] -3.70[98] -4.56[99] 0.66[100] -2.28[101] -2.66[102] -1.19[103]
17 PLA2G4A Cytosolic phospholipase A2 [104] -1.07[105] -4.25[106] 4.52[107] 3.73[108] 7.56[109] 0.44[110]
[1]
ref_hepatocyte APOB
Mean 165
Standard deviation 1.5e+02
Values 2.4e+02 15 8.3 2.2e+02 3.4e+02
[2]
HepG2 APOB
Mean 1.41e+03
Standard deviation 6.5e+02
Values 9.5e+02 1.9e+03
[3]
HepG2.C3A APOB
Mean 2.13e+03
Standard deviation 5.8e+02
Values 1.7e+03 2.5e+03
[4]
HuH.7 APOB
Mean 1.16e+03
Standard deviation 4.8e+02
Values 1.4e+03 1.5e+03 6.1e+02
[5]
SNU475 APOB
Mean 1.75
Standard deviation 0.12
Values 1.7 1.8
[6]
THLE APOB
Mean 2.04
Standard deviation 0.96
Values 2.7 1.4
[7]
liver APOB
Mean 6.85e+03
Standard deviation 4.5e+03
Values 2.9e+03 1.2e+04 3.6e+03 8.5e+03
[8]
ref_hepatocyte PPP2R1A
Mean 27.9
Standard deviation 5.4
Values 23 30 23 36 28
[9]
HepG2 PPP2R1A
Mean 107
Standard deviation 6.5
Values 1.1e+02 1e+02
[10]
HepG2.C3A PPP2R1A
Mean 84.7
Standard deviation 12
Values 93 76
[11]
HuH.7 PPP2R1A
Mean 77.2
Standard deviation 6.8
Values 84 70 78
[12]
SNU475 PPP2R1A
Mean 118
Standard deviation 14
Values 1.3e+02 1.1e+02
[13]
THLE PPP2R1A
Mean 83.3
Standard deviation 16
Values 72 94
[14]
liver PPP2R1A
Mean 43.9
Standard deviation 17
Values 51 30 65 30
[15]
ref_hepatocyte PPP2CA
Mean 27.3
Standard deviation 6.4
Values 27 38 22 24 25
[16]
HepG2 PPP2CA
Mean 72.8
Standard deviation 15
Values 62 83
[17]
HepG2.C3A PPP2CA
Mean 69.2
Standard deviation 19
Values 55 83
[18]
HuH.7 PPP2CA
Mean 42.8
Standard deviation 4.9
Values 43 38 48
[19]
SNU475 PPP2CA
Mean 83.9
Standard deviation 4.1
Values 81 87
[20]
THLE PPP2CA
Mean 102
Standard deviation 13
Values 92 1.1e+02
[21]
liver PPP2CA
Mean 36.1
Standard deviation 13
Values 49 27 46 23
[22]
ref_hepatocyte PPP2CB
Mean 25.5
Standard deviation 11
Values 15 43 27 17 26
[23]
HepG2 PPP2CB
Mean 43
Standard deviation 1.5
Values 44 42
[24]
HepG2.C3A PPP2CB
Mean 30.2
Standard deviation 0.78
Values 31 30
[25]
HuH.7 PPP2CB
Mean 30.6
Standard deviation 2.8
Values 28 34 30
[26]
SNU475 PPP2CB
Mean 34.2
Standard deviation 0.1
Values 34 34
[27]
THLE PPP2CB
Mean 35.7
Standard deviation 2.6
Values 37 34
[28]
liver PPP2CB
Mean 18.3
Standard deviation 7.2
Values 28 14 19 12
[29]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[30]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[31]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[32]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[33]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[34]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[35]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[36]
ref_hepatocyte PPP2R5A
Mean 14.2
Standard deviation 11
Values 8.7 5.8 6.2 21 30
[37]
HepG2 PPP2R5A
Mean 14.4
Standard deviation 0.58
Values 14 15
[38]
HepG2.C3A PPP2R5A
Mean 23.8
Standard deviation 5
Values 27 20
[39]
HuH.7 PPP2R5A
Mean 37.7
Standard deviation 14
Values 28 54 31
[40]
SNU475 PPP2R5A
Mean 21.9
Standard deviation 3
Values 24 20
[41]
THLE PPP2R5A
Mean 11.3
Standard deviation 0.33
Values 12 11
[42]
liver PPP2R5A
Mean 31.4
Standard deviation 5.3
Values 33 37 24 32
[43]
ref_hepatocyte PPP2R5C
Mean 14.1
Standard deviation 2.7
Values 15 17 10 13 15
[44]
HepG2 PPP2R5C
Mean 25.2
Standard deviation 5.7
Values 21 29
[45]
HepG2.C3A PPP2R5C
Mean 41.3
Standard deviation 0.87
Values 41 42
[46]
HuH.7 PPP2R5C
Mean 32.2
Standard deviation 4.1
Values 31 37 29
[47]
SNU475 PPP2R5C
Mean 49.7
Standard deviation 5.7
Values 54 46
[48]
THLE PPP2R5C
Mean 48.8
Standard deviation 6.3
Values 44 53
[49]
liver PPP2R5C
Mean 17.5
Standard deviation 1.8
Values 18 20 16 16
[50]
ref_hepatocyte PPP2R1B
Mean 12
Standard deviation 3.3
Values 7 14 11 15 13
[51]
HepG2 PPP2R1B
Mean 36.3
Standard deviation 12
Values 27 45
[52]
HepG2.C3A PPP2R1B
Mean 22.5
Standard deviation 5.6
Values 19 26
[53]
HuH.7 PPP2R1B
Mean 28.7
Standard deviation 4.1
Values 32 30 24
[54]
SNU475 PPP2R1B
Mean 26.6
Standard deviation 1.2
Values 26 27
[55]
THLE PPP2R1B
Mean 25.6
Standard deviation 5.7
Values 22 30
[56]
liver PPP2R1B
Mean 130
Standard deviation 78
Values 52 1.6e+02 82 2.2e+02
[57]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 12 8.5 7.2 7.5 8.3
[58]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 47 60
[59]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[60]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 37 36 34
[61]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 52 51
[62]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[63]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 24 38 22 37
[64]
ref_hepatocyte PPP2R5D
Mean 7.67
Standard deviation 1.8
Values 11 7.4 6.7 6.6 6.7
[65]
HepG2 PPP2R5D
Mean 40.3
Standard deviation 5.9
Values 36 44
[66]
HepG2.C3A PPP2R5D
Mean 30.4
Standard deviation 4.1
Values 27 33
[67]
HuH.7 PPP2R5D
Mean 21.5
Standard deviation 4.4
Values 26 17 22
[68]
SNU475 PPP2R5D
Mean 34.4
Standard deviation 4.8
Values 38 31
[69]
THLE PPP2R5D
Mean 35.6
Standard deviation 5.6
Values 32 40
[70]
liver PPP2R5D
Mean 9.05
Standard deviation 4.1
Values 11 5.8 14 5.4
[71]
ref_hepatocyte PPP2R5E
Mean 5.64
Standard deviation 2
Values 6.5 7.7 6.9 3.9 3.2
[72]
HepG2 PPP2R5E
Mean 13.5
Standard deviation 2.7
Values 12 15
[73]
HepG2.C3A PPP2R5E
Mean 13.6
Standard deviation 2.9
Values 11 16
[74]
HuH.7 PPP2R5E
Mean 9.42
Standard deviation 2.1
Values 12 9.4 7.3
[75]
SNU475 PPP2R5E
Mean 18.8
Standard deviation 1.2
Values 20 18
[76]
THLE PPP2R5E
Mean 18.2
Standard deviation 0.7
Values 18 19
[77]
liver PPP2R5E
Mean 9.17
Standard deviation 1.5
Values 11 9.6 9.4 7
[78]
ref_hepatocyte PTPN6
Mean 5.33
Standard deviation 3
Values 2.2 3.1 4.4 7.6 9.3
[79]
HepG2 PTPN6
Mean 8.54
Standard deviation 0.054
Values 8.5 8.6
[80]
HepG2.C3A PTPN6
Mean 8.69
Standard deviation 0.18
Values 8.6 8.8
[81]
HuH.7 PTPN6
Mean 12.4
Standard deviation 1.9
Values 13 10 14
[82]
SNU475 PTPN6
Mean 0.0694
Standard deviation 0.026
Values 0.088 0.051
[83]
THLE PTPN6
Mean 2.52
Standard deviation 0.67
Values 2 3
[84]
liver PTPN6
Mean 6.69
Standard deviation 2
Values 7.5 4.8 9.1 5.4
[85]
ref_hepatocyte PPP2R5B
Mean 2.1
Standard deviation 0.85
Values 1.5 2.2 2.4 3.3 1.2
[86]
HepG2 PPP2R5B
Mean 7.95
Standard deviation 0.71
Values 7.4 8.5
[87]
HepG2.C3A PPP2R5B
Mean 6.01
Standard deviation 3.4
Values 8.4 3.6
[88]
HuH.7 PPP2R5B
Mean 3.69
Standard deviation 1.6
Values 2.4 5.5 3.2
[89]
SNU475 PPP2R5B
Mean 4.72
Standard deviation 0.053
Values 4.8 4.7
[90]
THLE PPP2R5B
Mean 11.9
Standard deviation 2.7
Values 14 10
[91]
liver PPP2R5B
Mean 3.19
Standard deviation 1.1
Values 3.5 2 4.5 2.8
[92]
ref_hepatocyte FGR
Mean 0.788
Standard deviation 0.82
Values 0 0 0.94 1.1 1.9
[93]
HepG2 FGR
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A FGR
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 FGR
Mean 0.0127
Standard deviation 0.011
Values 0 0.019 0.019
[96]
SNU475 FGR
Mean 0.0565
Standard deviation 0.051
Values 0.093 0.02
[97]
THLE FGR
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[98]
liver FGR
Mean 3.62
Standard deviation 1.9
Values 2.9 2.7 2.4 6.5
[99]
ref_hepatocyte LRP8
Mean 0.63
Standard deviation 0.53
Values 0.6 1.3 1 0.12 0.11
[100]
HepG2 LRP8
Mean 7.47
Standard deviation 2.1
Values 9 6
[101]
HepG2.C3A LRP8
Mean 11.3
Standard deviation 0.38
Values 11 12
[102]
HuH.7 LRP8
Mean 14
Standard deviation 5.2
Values 18 8.1 16
[103]
SNU475 LRP8
Mean 13.1
Standard deviation 3.2
Values 11 15
[104]
THLE LRP8
Mean 14
Standard deviation 2
Values 13 15
[105]
liver LRP8
Mean 0.218
Standard deviation 0.079
Values 0.24 0.26 0.1 0.28
[106]
ref_hepatocyte PECAM1
Mean 0.592
Standard deviation 0.4
Values 0.3 0.085 0.67 0.82 1.1
[107]
HepG2 PECAM1
Mean 0.255
Standard deviation 0.077
Values 0.2 0.31
[108]
HepG2.C3A PECAM1
Mean 0.191
Standard deviation 0.078
Values 0.14 0.25
[109]
HuH.7 PECAM1
Mean 4.37
Standard deviation 0.94
Values 4.2 3.5 5.4
[110]
SNU475 PECAM1
Mean 0.192
Standard deviation 0.17
Values 0.074 0.31
[111]
THLE PECAM1
Mean 0.157
Standard deviation 0.087
Values 0.22 0.096
[112]
liver PECAM1
Mean 5.56
Standard deviation 2
Values 8.2 4.7 5.9 3.5
[113]
ref_hepatocyte PLA2G4A
Mean 0.0266
Standard deviation 0.038
Values 0 0 0 0.052 0.081
[114]
HepG2 PLA2G4A
Mean 0.0708
Standard deviation 0.027
Values 0.052 0.09
[115]
HepG2.C3A PLA2G4A
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[116]
HuH.7 PLA2G4A
Mean 2.84
Standard deviation 0.53
Values 2.5 2.6 3.4
[117]
SNU475 PLA2G4A
Mean 0.554
Standard deviation 0.44
Values 0.25 0.86
[118]
THLE PLA2G4A
Mean 8.43
Standard deviation 1.4
Values 9.4 7.5
[119]
liver PLA2G4A
Mean 0.772
Standard deviation 0.24
Values 0.56 1.1 0.64 0.77