REACTOME_APEX1_INDEPENDENT_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 POLB DNA polymerase beta [1] -0.67[2] -0.77[3] -1.31[4] -1.54[5] -1.26[6] -0.99[7]
2 NEIL2 Endonuclease 8-like 2 [8] -0.97[9] -1.17[10] -2.25[11] -2.25[12] -2.11[13] -0.52[14]
3 PNKP Bifunctional polynucleotide phosphatase/kinase [15] -0.72[16] -0.52[17] -0.17[18] -0.19[19] 0.36[20] 0.20[21]
4 OGG1 N-glycosylase/DNA lyase [22] 0.68[23] 0.65[24] 0.16[25] 0.16[26] 0.11[27] -0.22[28]
5 XRCC1 DNA repair protein XRCC1 [29] 0.89[30] 0.95[31] 1.42[32] 1.51[33] 1.58[34] -0.41[35]
6 LIG3 DNA ligase 3 [36] 1.44[37] 1.34[38] 1.82[39] 1.82[40] 0.96[41] 1.38[42]
7 NEIL1 Endonuclease 8-like 1 [43] -1.22[44] -0.30[45] -2.04[46] -1.69[47] -0.37[48] 1.47[49]
[1]
ref_hepatocyte POLB
Mean 10.8
Standard deviation 1.8
Values 9.3 13 12 8.8 11
[2]
HepG2 POLB
Mean 12.5
Standard deviation 2.5
Values 11 14
[3]
HepG2.C3A POLB
Mean 11.5
Standard deviation 2.8
Values 9.5 13
[4]
HuH.7 POLB
Mean 11.5
Standard deviation 2.4
Values 10 10 14
[5]
SNU475 POLB
Mean 4.06
Standard deviation 0.015
Values 4.1 4.1
[6]
THLE POLB
Mean 5.21
Standard deviation 0.74
Values 5.7 4.7
[7]
liver POLB
Mean 5.42
Standard deviation 4
Values 7.1 2.8 10 1.5
[8]
ref_hepatocyte NEIL2
Mean 7.91
Standard deviation 5.4
Values 7.2 17 3.4 5.1 6.7
[9]
HepG2 NEIL2
Mean 7.45
Standard deviation 0.93
Values 8.1 6.8
[10]
HepG2.C3A NEIL2
Mean 6.35
Standard deviation 1.1
Values 7.1 5.6
[11]
HuH.7 NEIL2
Mean 4.36
Standard deviation 1.1
Values 4.3 3.3 5.5
[12]
SNU475 NEIL2
Mean 1.82
Standard deviation 0.11
Values 1.7 1.9
[13]
THLE NEIL2
Mean 2.12
Standard deviation 0.29
Values 2.3 1.9
[14]
liver NEIL2
Mean 5.51
Standard deviation 2.3
Values 5.5 3.5 8.8 4.3
[15]
ref_hepatocyte PNKP
Mean 6.57
Standard deviation 3.1
Values 2.5 4.9 7.7 11 7.1
[16]
HepG2 PNKP
Mean 7.34
Standard deviation 0.51
Values 7.7 7
[17]
HepG2.C3A PNKP
Mean 8.3
Standard deviation 1.5
Values 9.4 7.3
[18]
HuH.7 PNKP
Mean 15.3
Standard deviation 4.8
Values 18 9.7 19
[19]
SNU475 PNKP
Mean 6.31
Standard deviation 0.25
Values 6.5 6.1
[20]
THLE PNKP
Mean 9.74
Standard deviation 0.14
Values 9.8 9.6
[21]
liver PNKP
Mean 7.53
Standard deviation 1.5
Values 8.8 6 8.8 6.5
[22]
ref_hepatocyte OGG1
Mean 5.01
Standard deviation 2.4
Values 4.1 2.4 6.9 8.1 3.6
[23]
HepG2 OGG1
Mean 14.8
Standard deviation 0.85
Values 14 15
[24]
HepG2.C3A OGG1
Mean 14.2
Standard deviation 2.8
Values 12 16
[25]
HuH.7 OGG1
Mean 14.7
Standard deviation 4.7
Values 17 9.2 18
[26]
SNU475 OGG1
Mean 6.11
Standard deviation 0.72
Values 5.6 6.6
[27]
THLE OGG1
Mean 6.23
Standard deviation 1.1
Values 5.5 7
[28]
liver OGG1
Mean 4.3
Standard deviation 1.9
Values 7.1 3.7 3.8 2.6
[29]
ref_hepatocyte XRCC1
Mean 3.8
Standard deviation 1.2
Values 5.2 3.1 5 2.8 3
[30]
HepG2 XRCC1
Mean 13
Standard deviation 0.87
Values 12 14
[31]
HepG2.C3A XRCC1
Mean 13.2
Standard deviation 1.4
Values 14 12
[32]
HuH.7 XRCC1
Mean 26.8
Standard deviation 4.3
Values 31 22 27
[33]
SNU475 XRCC1
Mean 11.8
Standard deviation 1.2
Values 11 13
[34]
THLE XRCC1
Mean 13.1
Standard deviation 0.99
Values 12 14
[35]
liver XRCC1
Mean 2.84
Standard deviation 1.8
Values 3.7 1.7 5 1
[36]
ref_hepatocyte LIG3
Mean 3.12
Standard deviation 1.4
Values 3.1 3.1 5.3 2.2 1.8
[37]
HepG2 LIG3
Mean 15.6
Standard deviation 1.4
Values 15 17
[38]
HepG2.C3A LIG3
Mean 14.3
Standard deviation 1.2
Values 15 13
[39]
HuH.7 LIG3
Mean 28.9
Standard deviation 9.5
Values 36 18 32
[40]
SNU475 LIG3
Mean 12.1
Standard deviation 1.6
Values 13 11
[41]
THLE LIG3
Mean 7.01
Standard deviation 1.3
Values 6.1 7.9
[42]
liver LIG3
Mean 8.07
Standard deviation 3.2
Values 3.9 9.5 7.4 11
[43]
ref_hepatocyte NEIL1
Mean 1.92
Standard deviation 1
Values 0.44 1.4 2.1 2.7 3
[44]
HepG2 NEIL1
Mean 1.52
Standard deviation 0.4
Values 1.2 1.8
[45]
HepG2.C3A NEIL1
Mean 2.83
Standard deviation 0.063
Values 2.9 2.8
[46]
HuH.7 NEIL1
Mean 1.23
Standard deviation 0.32
Values 0.86 1.4 1.4
[47]
SNU475 NEIL1
Mean 0.653
Standard deviation 0.18
Values 0.78 0.53
[48]
THLE NEIL1
Mean 1.72
Standard deviation 0.68
Values 2.2 1.2
[49]
liver NEIL1
Mean 5.33
Standard deviation 2.4
Values 8.7 3.6 5.2 3.9