REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CD | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.18[2] | -1.29[3] | -1.19[4] | -1.46[5] | -1.16[6] | -0.46[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.74[16] | -0.54[17] | -0.82[18] | -0.60[19] | -0.78[20] | -0.01[21] |
4 | PSME1 | Proteasome activator complex subunit 1 | [22] | -0.51[23] | -2.12[24] | -1.79[25] | -1.32[26] | -2.00[27] | -0.96[28] |
5 | PSME2 | Proteasome activator complex subunit 2 | [29] | -0.32[30] | -1.75[31] | -1.88[32] | -1.11[33] | -1.54[34] | -0.58[35] |
6 | PSMA7 | Proteasome subunit alpha type-7 | [36] | 0.63[37] | 0.72[38] | -0.63[39] | 0.52[40] | -0.06[41] | 0.44[42] |
7 | PSMB1 | Proteasome subunit beta type-1 | [43] | 0.18[44] | 0.27[45] | -0.83[46] | -0.72[47] | -0.10[48] | 0.28[49] |
8 | PSMB3 | Proteasome subunit beta type-3 | [50] | -0.30[51] | -1.11[52] | -0.10[53] | -0.75[54] | -1.01[55] | -0.02[56] |
9 | PSMB4 | Proteasome subunit beta type-4 | [57] | -0.06[58] | 0.09[59] | 0.19[60] | 0.68[61] | 0.53[62] | -0.35[63] |
10 | PSMB7 | Proteasome subunit beta type-7 | [64] | -1.00[65] | -1.01[66] | -0.90[67] | -1.09[68] | -0.79[69] | -0.78[70] |
11 | PSMB5 | Proteasome subunit beta type-5 | [71] | 1.40[72] | -0.05[73] | -0.15[74] | -0.37[75] | -0.23[76] | -0.31[77] |
12 | PSMA6 | Proteasome subunit alpha type-6 | [78] | 1.52[79] | 0.23[80] | 0.14[81] | 0.16[82] | 0.04[83] | -0.23[84] |
13 | PSMA4 | Proteasome subunit alpha type-4 | [85] | -0.41[86] | 0.24[87] | 0.01[88] | 0.46[89] | 0.15[90] | -0.31[91] |
14 | PSMC3 | 26S proteasome regulatory subunit 6A | [92] | -0.44[93] | -0.52[94] | 0.08[95] | -0.74[96] | -0.68[97] | 0.16[98] |
15 | PSMA3 | Proteasome subunit alpha type-3 | [99] | -1.03[100] | -0.04[101] | -0.74[102] | 0.01[103] | -0.58[104] | -0.06[105] |
16 | PSMB6 | Proteasome subunit beta type-6 | [106] | -0.48[107] | -0.34[108] | -0.22[109] | -0.54[110] | -0.94[111] | 0.10[112] |
17 | PSMA2 | Proteasome subunit alpha type-2 | [113] | -0.56[114] | 0.39[115] | 0.69[116] | -0.04[117] | 0.20[118] | 0.32[119] |
18 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [120] | -0.04[121] | -0.04[122] | 0.13[123] | 0.66[124] | -0.01[125] | 0.00[126] |
19 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [127] | -0.13[128] | 0.23[129] | 0.07[130] | -0.42[131] | -0.09[132] | -0.18[133] |
20 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [134] | 0.04[135] | 0.27[136] | 0.38[137] | -0.15[138] | 0.48[139] | -0.15[140] |
21 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [141] | 1.57[142] | 0.74[143] | 0.79[144] | 0.96[145] | 2.12[146] | 0.88[147] |
22 | PSMC1 | 26S proteasome regulatory subunit 4 | [148] | -0.10[149] | -0.05[150] | -0.73[151] | 1.14[152] | 0.53[153] | 0.04[154] |
23 | PSMA1 | Proteasome subunit alpha type-1 | [155] | 0.08[156] | 0.46[157] | 0.49[158] | 0.72[159] | 0.09[160] | 0.53[161] |
24 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [162] | 1.70[163] | 1.70[164] | 2.69[165] | 0.79[166] | 1.45[167] | 0.76[168] |
25 | PSMC5 | 26S proteasome regulatory subunit 8 | [169] | 0.40[170] | 0.28[171] | 0.33[172] | 0.13[173] | 0.41[174] | 0.30[175] |
26 | ANAPC11 | Anaphase-promoting complex subunit 11 | [176] | -0.81[177] | -0.28[178] | -0.75[179] | -0.99[180] | -0.77[181] | 0.02[182] |
27 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [183] | 0.79[184] | 0.28[185] | 0.84[186] | 0.66[187] | 0.75[188] | 0.01[189] |
28 | PSMB8 | Proteasome subunit beta type-8 | [190] | -1.60[191] | -2.21[192] | -9.45[193] | 0.63[194] | -0.81[195] | -0.67[196] |
29 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [197] | -0.03[198] | 0.57[199] | 0.80[200] | 0.52[201] | 0.42[202] | -0.13[203] |
30 | PSMC4 | 26S proteasome regulatory subunit 6B | [204] | 0.40[205] | 0.42[206] | 0.33[207] | 0.15[208] | 0.13[209] | 0.35[210] |
31 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [211] | -0.76[212] | -0.28[213] | -1.40[214] | -0.47[215] | 0.20[216] | -0.24[217] |
32 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [218] | 0.44[219] | 0.54[220] | 1.01[221] | 0.59[222] | -0.04[223] | -0.05[224] |
33 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [225] | -0.38[226] | -0.31[227] | -0.64[228] | 0.20[229] | 0.14[230] | -0.13[231] |
34 | PSMC6 | 26S proteasome regulatory subunit 10B | [232] | -0.08[233] | 1.48[234] | 0.28[235] | 0.56[236] | 0.36[237] | 0.52[238] |
35 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [239] | 0.80[240] | 0.40[241] | 0.97[242] | 0.97[243] | 0.99[244] | 1.35[245] |
36 | PSMC2 | 26S proteasome regulatory subunit 7 | [246] | 0.55[247] | 0.94[248] | 0.69[249] | 1.37[250] | 1.06[251] | 1.40[252] |
37 | CDC26 | Anaphase-promoting complex subunit CDC26 | [253] | -1.76[254] | -1.19[255] | -1.27[256] | -1.70[257] | -0.97[258] | -0.79[259] |
38 | PSME3 | Proteasome activator complex subunit 3 | [260] | 1.78[261] | 1.49[262] | 1.14[263] | 1.39[264] | 1.52[265] | 0.97[266] |
39 | UBE2E1 | Ubiquitin-conjugating enzyme E2 E1 | [267] | 0.06[268] | 0.40[269] | 1.06[270] | 0.84[271] | 0.94[272] | -1.39[273] |
40 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [274] | 1.54[275] | 1.85[276] | 1.70[277] | 2.20[278] | 2.07[279] | 2.15[280] |
41 | PSMB10 | Proteasome subunit beta type-10 | [281] | -1.18[282] | -0.60[283] | -2.51[284] | -0.01[285] | -1.31[286] | 0.00[287] |
42 | PSMA5 | Proteasome subunit alpha type-5 | [288] | 1.87[289] | 2.28[290] | 1.82[291] | 2.25[292] | 1.68[293] | 1.99[294] |
43 | PSMF1 | Proteasome inhibitor PI31 subunit | [295] | 2.25[296] | 2.28[297] | 1.06[298] | 1.26[299] | 0.88[300] | 1.93[301] |
44 | ANAPC16 | Anaphase-promoting complex subunit 16 | [302] | 1.21[303] | 2.01[304] | 0.80[305] | 0.90[306] | 0.97[307] | 1.96[308] |
45 | ANAPC5 | Anaphase-promoting complex subunit 5 | [309] | 1.89[310] | 2.65[311] | 2.76[312] | 1.66[313] | 1.96[314] | 2.13[315] |
46 | PSMB2 | Proteasome subunit beta type-2 | [316] | 2.03[317] | 1.75[318] | 2.11[319] | 2.55[320] | 2.40[321] | 2.48[322] |
47 | PSMB9 | Proteasome subunit beta type-9 | [323] | -1.98[324] | -4.61[325] | -6.94[326] | 1.80[327] | -0.60[328] | -0.41[329] |
48 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [330] | 0.41[331] | 0.89[332] | -0.13[333] | 0.43[334] | 0.73[335] | 0.81[336] |
49 | CDC27 | Cell division cycle protein 27 homolog | [337] | 1.24[338] | 2.16[339] | 1.47[340] | 2.51[341] | 1.89[342] | 1.57[343] |
50 | CDC16 | Cell division cycle protein 16 homolog | [344] | 0.53[345] | 0.84[346] | 0.14[347] | 0.90[348] | 1.19[349] | 1.29[350] |
51 | UBE2C | Ubiquitin-conjugating enzyme E2 C | [351] | 0.78[352] | 1.26[353] | 1.97[354] | 1.45[355] | 2.18[356] | -2.38[357] |
52 | UBE2S | Ubiquitin-conjugating enzyme E2 S | [358] | 1.47[359] | 1.13[360] | 3.27[361] | 2.29[362] | 3.49[363] | -1.17[364] |
53 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [365] | 0.96[366] | 1.27[367] | 1.27[368] | 2.10[369] | 1.29[370] | 0.79[371] |
54 | PSME4 | Proteasome activator complex subunit 4 | [372] | 2.49[373] | 3.39[374] | 3.36[375] | 2.66[376] | 2.48[377] | 3.06[378] |
55 | AURKA | Aurora kinase A | [379] | 2.73[380] | 3.08[381] | 2.53[382] | 2.94[383] | 2.69[384] | -1.38[385] |
56 | CDC23 | Cell division cycle protein 23 homolog | [386] | 1.40[387] | 1.69[388] | 1.90[389] | 2.36[390] | 1.90[391] | 1.62[392] |
57 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [393] | 1.38[394] | 0.92[395] | 2.46[396] | 2.49[397] | 2.43[398] | 2.24[399] |
58 | FZR1 | Fizzy-related protein homolog | [400] | 1.77[401] | 1.50[402] | 1.54[403] | 1.36[404] | 1.79[405] | 2.04[406] |
59 | ANAPC7 | Anaphase-promoting complex subunit 7 | [407] | 2.02[408] | 2.51[409] | 1.94[410] | 2.22[411] | 2.32[412] | 1.61[413] |
60 | ANAPC2 | Anaphase-promoting complex subunit 2 | [414] | 1.63[415] | 1.16[416] | 1.72[417] | 1.36[418] | 1.16[419] | 1.47[420] |
61 | AURKB | Aurora kinase B | [421] | 1.61[422] | 2.06[423] | 3.04[424] | 1.66[425] | 2.04[426] | -1.93[427] |
62 | PLK1 | Serine/threonine-protein kinase PLK1 | [428] | 3.51[429] | 3.34[430] | 3.15[431] | 2.57[432] | 3.45[433] | -1.21[434] |
63 | CDC20 | Cell division cycle protein 20 homolog | [435] | 3.38[436] | 3.49[437] | 3.81[438] | 3.83[439] | 4.32[440] | -0.89[441] |
64 | PTTG1 | Securin | [442] | 2.52[443] | 3.27[444] | 3.82[445] | 2.74[446] | 3.87[447] | -0.65[448] |
65 | ANAPC1 | Anaphase-promoting complex subunit 1 | [449] | 3.43[450] | 3.70[451] | 3.54[452] | 3.25[453] | 3.11[454] | 2.87[455] |
66 | SKP2 | S-phase kinase-associated protein 2 | [456] | 2.33[457] | 2.88[458] | 3.97[459] | 2.58[460] | 2.51[461] | 2.50[462] |
67 | RB1 | Retinoblastoma-associated protein | [463] | 2.24[464] | 2.83[465] | 3.34[466] | 3.60[467] | 3.76[468] | 2.90[469] |
68 | ANAPC4 | Anaphase-promoting complex subunit 4 | [470] | 1.21[471] | 2.23[472] | 2.51[473] | 2.51[474] | 1.83[475] | 2.40[476] |
69 | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 | [477] | 1.81[478] | 2.77[479] | 3.07[480] | 2.84[481] | 2.45[482] | 1.92[483] |
70 | ANAPC10 | Anaphase-promoting complex subunit 10 | [484] | 0.78[485] | 1.76[486] | 1.10[487] | 1.10[488] | 1.72[489] | 1.54[490] |
71 | SEM1 | Putative protein SEM1, isoform 2 | [491] | [492] | [493] | [494] | [495] | [496] | [497] |
72 | ANAPC15 | Anaphase-promoting complex subunit 15 | [498] | [499] | [500] | [501] | [502] | [503] | [504] |
73 | PSMA8 | Proteasome subunit alpha type-7-like | [505] | [506] | [507] | [508] | [509] | [510] | [511] |
74 | PSMB11 | Proteasome subunit beta type-11 | [512] | [513] | [514] | [515] | [516] | [517] | [518] |