REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -0.56[2] | -0.96[3] | -0.97[4] | -0.88[5] | -0.83[6] | -0.09[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.12[16] | -0.21[17] | -0.61[18] | -0.02[19] | -0.45[20] | 0.36[21] |
4 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [22] | 2.31[23] | 2.02[24] | 2.90[25] | 1.37[26] | 1.77[27] | 1.13[28] |
5 | ANAPC11 | Anaphase-promoting complex subunit 11 | [29] | -0.20[30] | 0.04[31] | -0.53[32] | -0.41[33] | -0.45[34] | 0.39[35] |
6 | CDC26 | Anaphase-promoting complex subunit CDC26 | [36] | -1.14[37] | -0.87[38] | -1.06[39] | -1.12[40] | -0.65[41] | -0.42[42] |
7 | UBE2E1 | Ubiquitin-conjugating enzyme E2 E1 | [43] | 0.68[44] | 0.72[45] | 1.27[46] | 1.42[47] | 1.27[48] | -1.03[49] |
8 | BUB3 | Mitotic checkpoint protein BUB3 | [50] | 1.95[51] | 2.63[52] | 1.86[53] | 1.60[54] | 2.64[55] | 1.19[56] |
9 | ANAPC16 | Anaphase-promoting complex subunit 16 | [57] | 1.82[58] | 2.33[59] | 1.01[60] | 1.48[61] | 1.30[62] | 2.33[63] |
10 | ANAPC5 | Anaphase-promoting complex subunit 5 | [64] | 2.51[65] | 2.98[66] | 2.98[67] | 2.24[68] | 2.28[69] | 2.50[70] |
11 | CDC27 | Cell division cycle protein 27 homolog | [71] | 1.85[72] | 2.49[73] | 1.68[74] | 3.09[75] | 2.21[76] | 1.93[77] |
12 | CDC16 | Cell division cycle protein 16 homolog | [78] | 1.14[79] | 1.17[80] | 0.36[81] | 1.48[82] | 1.51[83] | 1.66[84] |
13 | UBE2C | Ubiquitin-conjugating enzyme E2 C | [85] | 1.40[86] | 1.58[87] | 2.19[88] | 2.03[89] | 2.51[90] | -2.02[91] |
14 | UBE2S | Ubiquitin-conjugating enzyme E2 S | [92] | 2.08[93] | 1.45[94] | 3.48[95] | 2.87[96] | 3.81[97] | -0.81[98] |
15 | MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A | [99] | 2.23[100] | 3.16[101] | 2.33[102] | 1.95[103] | 2.65[104] | -1.09[105] |
16 | CDC23 | Cell division cycle protein 23 homolog | [106] | 2.01[107] | 2.01[108] | 2.11[109] | 2.94[110] | 2.23[111] | 1.98[112] |
17 | ANAPC7 | Anaphase-promoting complex subunit 7 | [113] | 2.64[114] | 2.84[115] | 2.15[116] | 2.81[117] | 2.65[118] | 1.97[119] |
18 | ANAPC2 | Anaphase-promoting complex subunit 2 | [120] | 2.24[121] | 1.48[122] | 1.94[123] | 1.94[124] | 1.49[125] | 1.83[126] |
19 | CDC20 | Cell division cycle protein 20 homolog | [127] | 3.99[128] | 3.81[129] | 4.02[130] | 4.41[131] | 4.65[132] | -0.52[133] |
20 | ANAPC1 | Anaphase-promoting complex subunit 1 | [134] | 4.04[135] | 4.03[136] | 3.75[137] | 3.83[138] | 3.43[139] | 3.24[140] |
21 | ANAPC4 | Anaphase-promoting complex subunit 4 | [141] | 1.83[142] | 2.55[143] | 2.72[144] | 3.09[145] | 2.15[146] | 2.76[147] |
22 | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 | [148] | 2.43[149] | 3.10[150] | 3.28[151] | 3.42[152] | 2.77[153] | 2.29[154] |
23 | ANAPC10 | Anaphase-promoting complex subunit 10 | [155] | 1.40[156] | 2.09[157] | 1.32[158] | 1.68[159] | 2.05[160] | 1.90[161] |
24 | NEK2 | Serine/threonine-protein kinase Nek2 | [162] | 2.66[163] | 3.52[164] | 3.98[165] | 4.04[166] | 4.09[167] | -0.49[168] |
25 | BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | [169] | 3.77[170] | 4.28[171] | 4.04[172] | 4.97[173] | 4.84[174] | 0.19[175] |
26 | ANAPC15 | Anaphase-promoting complex subunit 15 | [176] | [177] | [178] | [179] | [180] | [181] | [182] |