REACTOME_ANTIMICROBIAL_PEPTIDES | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CLU | Clusterin | [1] | -1.98[2] | -2.15[3] | 0.55[4] | 0.52[5] | -2.15[6] | 0.59[7] |
2 | PLA2G2A | Phospholipase A2, membrane associated | [8] | -1.88[9] | -7.77[10] | -14.05[11] | -11.31[12] | -9.56[13] | -1.01[14] |
3 | LEAP2 | Liver-expressed antimicrobial peptide 2 | [15] | -2.44[16] | -2.48[17] | -3.18[18] | -5.75[19] | -5.84[20] | -0.01[21] |
4 | ATOX1 | Copper transport protein ATOX1 | [22] | 0.21[23] | -2.07[24] | -0.97[25] | 1.55[26] | 3.07[27] | -1.26[28] |
5 | LCN2 | Neutrophil gelatinase-associated lipocalin | [29] | -1.73[30] | -0.54[31] | -5.71[32] | -3.77[33] | -0.31[34] | -2.45[35] |
6 | LYZ | Lysozyme C | [36] | 5.06[37] | 5.32[38] | 4.00[39] | -1.32[40] | -0.25[41] | -1.43[42] |
7 | PGLYRP2 | N-acetylmuramoyl-L-alanine amidase | [43] | -4.33[44] | -5.34[45] | -9.87[46] | -8.98[47] | [48] | 1.24[49] |
8 | S100A9 | Protein S100-A9 | [50] | -3.11[51] | -7.81[52] | -4.51[53] | -4.12[54] | -3.44[55] | -1.45[56] |
9 | DEFB1 | Beta-defensin 1 | [57] | 0.60[58] | -2.23[59] | -1.84[60] | -6.22[61] | -6.77[62] | -2.29[63] |
10 | CD4 | T-cell surface glycoprotein CD4 | [64] | -2.69[65] | -2.73[66] | -4.03[67] | -2.85[68] | -3.70[69] | 0.41[70] |
11 | PRSS3 | Trypsin-3 | [71] | -8.44[72] | -8.91[73] | -0.17[74] | -7.62[75] | 1.29[76] | -3.39[77] |
12 | PDZD11 | PDZ domain-containing protein 11 | [78] | 2.89[79] | 0.50[80] | 1.38[81] | 4.98[82] | 6.08[83] | -0.22[84] |
13 | S100A8 | Protein S100-A8 | [85] | [86] | [87] | [88] | -4.87[89] | [90] | 0.54[91] |
14 | RNASE7 | Ribonuclease 7 | [92] | -6.64[93] | -4.85[94] | -7.90[95] | -3.86[96] | -0.39[97] | -4.50[98] |
15 | RNASE6 | Ribonuclease K6 | [99] | [100] | [101] | [102] | [103] | [104] | -0.31[105] |
16 | TLR2 | Toll-like receptor 2 | [106] | -0.48[107] | -1.28[108] | -6.96[109] | -0.37[110] | 7.59[111] | 1.74[112] |
17 | DEFB4B | [113] | [114] | [115] | [116] | [117] | [118] | [119] | |
18 | BPIFB2 | BPI fold-containing family B member 2 | [120] | 7.19[121] | 8.18[122] | -3.56[123] | -0.73[124] | 0.51[125] | -0.93[126] |
19 | CTSG | Cathepsin G | [127] | [128] | [129] | [130] | [131] | [132] | -1.67[133] |
20 | DEFB103B | [134] | [135] | [136] | [137] | [138] | [139] | [140] | |
21 | GNLY | Granulysin | [141] | -3.60[142] | [143] | [144] | [145] | -1.28[146] | 0.32[147] |
22 | TLR1 | Toll-like receptor 1 | [148] | -0.30[149] | [150] | -4.85[151] | 4.21[152] | 6.59[153] | 2.56[154] |
23 | CCR2 | C-C chemokine receptor type 2 | [155] | [156] | [157] | 1.90[158] | [159] | [160] | 1.36[161] |
24 | PI3 | Elafin | [162] | 1.11[163] | -3.83[164] | 1.40[165] | 3.50[166] | 7.01[167] | [168] |
25 | CCR6 | C-C chemokine receptor type 6 | [169] | 5.28[170] | 3.71[171] | 6.39[172] | 3.11[173] | 3.68[174] | 0.19[175] |
26 | ATP7A | Copper-transporting ATPase 1 | [176] | 5.82[177] | 3.37[178] | 4.99[179] | 9.53[180] | 9.11[181] | 3.79[182] |
27 | SLC11A1 | Natural resistance-associated macrophage protein 1 | [183] | 3.61[184] | 2.25[185] | 1.45[186] | 1.02[187] | 4.25[188] | 3.18[189] |
28 | ITLN1 | Intelectin-1 | [190] | [191] | [192] | 0.66[193] | -1.11[194] | 5.74[195] | 2.02[196] |
29 | DEFA3 | Neutrophil defensin 3 | [197] | [198] | [199] | [200] | [201] | [202] | [203] |
30 | CAMP | Cathelicidin antimicrobial peptide | [204] | -2.83[205] | [206] | -3.93[207] | [208] | 3.36[209] | 0.64[210] |
31 | DEFB132 | Beta-defensin 132 | [211] | [212] | [213] | [214] | [215] | [216] | 0.13[217] |
32 | REG3A | Regenerating islet-derived protein 3-alpha | [218] | -0.32[219] | [220] | -0.92[221] | [222] | 0.09[223] | -4.37[224] |
33 | DEFA5 | Defensin-5 | [225] | [226] | [227] | [228] | [229] | [230] | [231] |
34 | BPIFB1 | BPI fold-containing family B member 1 | [232] | 0.13[233] | -3.62[234] | 0.30[235] | 0.24[236] | 0.41[237] | -2.43[238] |
35 | ELANE | Neutrophil elastase | [239] | [240] | [241] | -0.27[242] | 2.95[243] | 1.56[244] | 2.55[245] |
36 | LTF | Lactotransferrin | [246] | -1.32[247] | [248] | 2.79[249] | [250] | 3.70[251] | 4.12[252] |
37 | BPI | Bactericidal permeability-increasing protein | [253] | 0.28[254] | [255] | [256] | 0.91[257] | [258] | 1.73[259] |
38 | BPIFB6 | BPI fold-containing family B member 6 | [260] | 1.78[261] | 3.28[262] | [263] | [264] | [265] | [266] |
39 | PRTN3 | Myeloblastin | [267] | 3.81[268] | [269] | 6.60[270] | 4.94[271] | 3.31[272] | 4.08[273] |
40 | BPIFB4 | BPI fold-containing family B member 4 | [274] | 1.01[275] | [276] | 2.31[277] | 6.58[278] | 3.89[279] | -0.77[280] |
41 | CHGA | Chromogranin-A | [281] | 0.42[282] | 0.27[283] | [284] | 7.42[285] | 5.19[286] | 1.79[287] |
42 | PGLYRP3 | Peptidoglycan recognition protein 3 | [288] | [289] | [290] | [291] | [292] | [293] | [294] |
43 | DEFB119 | Beta-defensin 119 | [295] | [296] | [297] | [298] | [299] | [300] | [301] |
44 | DEFA6 | Defensin-6 | [302] | [303] | [304] | [305] | [306] | [307] | [308] |
45 | PGLYRP1 | Peptidoglycan recognition protein 1 | [309] | [310] | [311] | [312] | [313] | [314] | [315] |
46 | DEFB104B | [316] | [317] | [318] | [319] | [320] | [321] | [322] | |
47 | DEFB105B | [323] | [324] | [325] | [326] | [327] | [328] | [329] | |
48 | DEFB108B | Beta-defensin 108B | [330] | [331] | [332] | [333] | [334] | [335] | [336] |
49 | DEFB130B | Beta-defensin 130B | [337] | [338] | [339] | [340] | [341] | [342] | [343] |
50 | DEFB103A | Beta-defensin 103 | [344] | [345] | [346] | [347] | [348] | [349] | [350] |
51 | DEFB129 | Beta-defensin 129 | [351] | [352] | [353] | [354] | [355] | [356] | [357] |
52 | DEFB106A | Beta-defensin 106 | [358] | [359] | [360] | [361] | [362] | [363] | [364] |
53 | ART1 | GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 | [365] | [366] | [367] | [368] | [369] | [370] | [371] |
54 | S100A7A | Protein S100-A7A | [372] | [373] | [374] | [375] | [376] | [377] | [378] |
55 | RNASE3 | Eosinophil cationic protein | [379] | [380] | [381] | [382] | [383] | [384] | [385] |
56 | DEFA1 | Neutrophil defensin 1 | [386] | [387] | [388] | [389] | [390] | [391] | [392] |
57 | DEFB110 | Beta-defensin 110 | [393] | [394] | [395] | [396] | [397] | [398] | [399] |
58 | HTN1 | Histatin-1 | [400] | [401] | [402] | [403] | [404] | [405] | [406] |
59 | S100A7 | Protein S100-A7 | [407] | [408] | [409] | [410] | [411] | [412] | [413] |
60 | DEFB113 | Beta-defensin 113 | [414] | [415] | [416] | [417] | [418] | [419] | [420] |
61 | DEFB107B | [421] | [422] | [423] | [424] | [425] | [426] | [427] | |
62 | DEFB123 | Beta-defensin 123 | [428] | [429] | [430] | [431] | [432] | [433] | [434] |
63 | DEFB121 | Beta-defensin 121 | [435] | [436] | [437] | [438] | [439] | [440] | [441] |
64 | DEFB133 | Beta-defensin 133 | [442] | [443] | [444] | [445] | [446] | [447] | [448] |
65 | DEFB136 | Beta-defensin 136 | [449] | [450] | [451] | [452] | [453] | [454] | [455] |
66 | DEFB112 | Beta-defensin 112 | [456] | [457] | [458] | [459] | [460] | [461] | [462] |
67 | RNASE8 | Ribonuclease 8 | [463] | [464] | [465] | [466] | [467] | [468] | [469] |
68 | REG3G | Regenerating islet-derived protein 3-gamma | [470] | [471] | [472] | [473] | [474] | [475] | [476] |
69 | DEFA1B | [477] | [478] | [479] | [480] | [481] | [482] | [483] | |
70 | DEFB126 | Beta-defensin 126 | [484] | [485] | [486] | [487] | [488] | [489] | [490] |
71 | BPIFA2 | BPI fold-containing family A member 2 | [491] | [492] | [493] | [494] | [495] | [496] | [497] |
72 | DCD | Dermcidin | [498] | [499] | [500] | [501] | [502] | [503] | [504] |
73 | DEFB116 | Beta-defensin 116 | [505] | [506] | [507] | [508] | [509] | [510] | [511] |
74 | BPIFA1 | BPI fold-containing family A member 1 | [512] | [513] | [514] | [515] | [516] | [517] | [518] |
75 | SEMG1 | Semenogelin-1 | [519] | [520] | [521] | [522] | [523] | [524] | [525] |
76 | HTN3 | Histatin-3 | [526] | [527] | [528] | [529] | [530] | [531] | [532] |
77 | DEFB4A | Beta-defensin 4A | [533] | [534] | [535] | [536] | [537] | [538] | [539] |
78 | DEFB131A | Beta-defensin 131A | [540] | [541] | [542] | [543] | [544] | [545] | [546] |
79 | DEFB125 | Beta-defensin 125 | [547] | [548] | [549] | [550] | [551] | [552] | [553] |
80 | DEFB135 | Beta-defensin 135 | [554] | [555] | [556] | [557] | [558] | [559] | [560] |
81 | DEFB114 | Beta-defensin 114 | [561] | [562] | [563] | [564] | [565] | [566] | [567] |
82 | DEFB128 | Beta-defensin 128 | [568] | [569] | [570] | [571] | [572] | [573] | [574] |
83 | DEFB115 | Beta-defensin 115 | [575] | [576] | [577] | [578] | [579] | [580] | [581] |
84 | DEFB134 | Beta-defensin 134 | [582] | [583] | [584] | [585] | [586] | [587] | [588] |
85 | DEFB107A | Beta-defensin 107 | [589] | [590] | [591] | [592] | [593] | [594] | [595] |
86 | DEFB124 | Beta-defensin 124 | [596] | [597] | [598] | [599] | [600] | [601] | [602] |
87 | DEFB118 | Beta-defensin 118 | [603] | [604] | [605] | [606] | [607] | [608] | [609] |
88 | DEFA4 | Neutrophil defensin 4 | [610] | [611] | [612] | [613] | [614] | [615] | [616] |
89 | DEFB106B | [617] | [618] | [619] | [620] | [621] | [622] | [623] | |
90 | EPPIN | Eppin | [624] | [625] | [626] | [627] | [628] | [629] | [630] |
91 | PGLYRP4 | Peptidoglycan recognition protein 4 | [631] | [632] | [633] | [634] | [635] | [636] | [637] |
92 | DEFB130A | Beta-defensin 130A | [638] | [639] | [640] | [641] | [642] | [643] | [644] |
93 | DEFB105A | Beta-defensin 105 | [645] | [646] | [647] | [648] | [649] | [650] | [651] |
94 | DEFB127 | Beta-defensin 127 | [652] | [653] | [654] | [655] | [656] | [657] | [658] |
95 | DEFB104A | Beta-defensin 104 | [659] | [660] | [661] | [662] | [663] | [664] | [665] |
96 | EPPIN-WFDC6 | [666] | [667] | [668] | [669] | [670] | [671] | [672] | |
97 | PRSS2 | Trypsin-2 | [673] | [674] | [675] | [676] | [677] | [678] | [679] |