REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FGG | Fibrinogen gamma chain | [1] | -3.57[2] | -2.56[3] | -2.21[4] | -10.29[5] | -12.06[6] | -0.41[7] |
2 | FGA | Fibrinogen alpha chain | [8] | -3.23[9] | -2.81[10] | -2.10[11] | -9.51[12] | -12.08[13] | 0.26[14] |
3 | FGB | Fibrinogen beta chain | [15] | -4.44[16] | -3.58[17] | -1.12[18] | -7.63[19] | -10.71[20] | 1.04[21] |
4 | B2M | Beta-2-microglobulin | [22] | -0.26[23] | 0.00[24] | -0.58[25] | 1.71[26] | 1.70[27] | -0.45[28] |
5 | UBB | Polyubiquitin-B | [29] | 0.82[30] | 0.67[31] | 0.90[32] | 0.21[33] | 0.79[34] | -1.73[35] |
6 | CALR | Calreticulin | [36] | 2.06[37] | 1.63[38] | 1.46[39] | 0.86[40] | 1.28[41] | -0.85[42] |
7 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [43] | [44] | [45] | [46] | [47] | [48] | [49] |
8 | UBC | Polyubiquitin-C | [50] | 1.27[51] | 1.42[52] | 1.27[53] | 1.06[54] | 1.17[55] | -1.28[56] |
9 | HLA-A | HLA class I histocompatibility antigen, A-68 alpha chain | [57] | 1.85[58] | 2.14[59] | -3.76[60] | 2.73[61] | 1.84[62] | -1.93[63] |
10 | HLA-C | HLA class I histocompatibility antigen, Cw-17 alpha chain | [64] | 0.99[65] | 0.37[66] | -3.41[67] | 1.96[68] | 2.13[69] | -1.54[70] |
11 | HLA-B | HLA class I histocompatibility antigen, B-73 alpha chain | [71] | 0.02[72] | -1.26[73] | -5.52[74] | 3.39[75] | 2.51[76] | -1.19[77] |
12 | SEC61G | Protein transport protein Sec61 subunit gamma | [78] | -0.28[79] | 0.15[80] | 0.45[81] | -0.23[82] | -0.55[83] | -3.20[84] |
13 | PDIA3 | Protein disulfide-isomerase A3 | [85] | 2.69[86] | 2.44[87] | 1.89[88] | 2.50[89] | 2.31[90] | -0.60[91] |
14 | PSME1 | Proteasome activator complex subunit 1 | [92] | 1.50[93] | -0.17[94] | 0.30[95] | 0.34[96] | -0.05[97] | -2.23[98] |
15 | CD14 | Monocyte differentiation antigen CD14 | [99] | -5.31[100] | -5.34[101] | -2.44[102] | -1.81[103] | -2.88[104] | -0.36[105] |
16 | SEC61B | Protein transport protein Sec61 subunit beta | [106] | 0.24[107] | 1.06[108] | 0.38[109] | -0.34[110] | 0.08[111] | -2.00[112] |
17 | PSME2 | Proteasome activator complex subunit 2 | [113] | 1.68[114] | 0.21[115] | 0.21[116] | 0.56[117] | 0.41[118] | -1.85[119] |
18 | PSMA7 | Proteasome subunit alpha type-7 | [120] | 2.64[121] | 2.68[122] | 1.46[123] | 2.19[124] | 1.89[125] | -0.83[126] |
19 | PSMB1 | Proteasome subunit beta type-1 | [127] | 2.18[128] | 2.23[129] | 1.26[130] | 0.94[131] | 1.85[132] | -0.99[133] |
20 | HLA-E | HLA class I histocompatibility antigen, alpha chain E | [134] | 1.19[135] | 1.09[136] | 0.74[137] | 2.88[138] | 1.64[139] | 0.33[140] |
21 | PSMB3 | Proteasome subunit beta type-3 | [141] | 1.70[142] | 0.85[143] | 1.99[144] | 0.92[145] | 0.95[146] | -1.29[147] |
22 | PSMB4 | Proteasome subunit beta type-4 | [148] | 1.94[149] | 2.05[150] | 2.28[151] | 2.35[152] | 2.49[153] | -1.62[154] |
23 | PSMB7 | Proteasome subunit beta type-7 | [155] | 1.00[156] | 0.94[157] | 1.19[158] | 0.57[159] | 1.16[160] | -2.06[161] |
24 | HMGB1 | High mobility group protein B1 | [162] | 2.72[163] | 3.51[164] | 3.33[165] | 3.45[166] | 3.06[167] | -0.41[168] |
25 | PSMB5 | Proteasome subunit beta type-5 | [169] | 3.40[170] | 1.91[171] | 1.94[172] | 1.30[173] | 1.72[174] | -1.58[175] |
26 | PSMA6 | Proteasome subunit alpha type-6 | [176] | 3.53[177] | 2.18[178] | 2.22[179] | 1.82[180] | 1.99[181] | -1.50[182] |
27 | PSMA4 | Proteasome subunit alpha type-4 | [183] | 1.60[184] | 2.20[185] | 2.10[186] | 2.13[187] | 2.10[188] | -1.58[189] |
28 | PSMC3 | 26S proteasome regulatory subunit 6A | [190] | 1.56[191] | 1.44[192] | 2.16[193] | 0.93[194] | 1.27[195] | -1.11[196] |
29 | PSMA3 | Proteasome subunit alpha type-3 | [197] | 0.98[198] | 1.92[199] | 1.35[200] | 1.67[201] | 1.37[202] | -1.33[203] |
30 | VAMP8 | Vesicle-associated membrane protein 8 | [204] | 0.45[205] | 1.63[206] | 0.29[207] | -1.83[208] | -0.40[209] | -2.22[210] |
31 | PSMB6 | Proteasome subunit beta type-6 | [211] | 1.53[212] | 1.62[213] | 1.87[214] | 1.13[215] | 1.01[216] | -1.17[217] |
32 | PSMA2 | Proteasome subunit alpha type-2 | [218] | 1.44[219] | 2.34[220] | 2.78[221] | 1.62[222] | 2.15[223] | -0.95[224] |
33 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [225] | 1.96[226] | 1.91[227] | 2.22[228] | 2.33[229] | 1.94[230] | -1.27[231] |
34 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [232] | 1.88[233] | 2.19[234] | 2.16[235] | 1.24[236] | 1.86[237] | -1.45[238] |
35 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [239] | 2.04[240] | 2.23[241] | 2.47[242] | 1.52[243] | 2.43[244] | -1.42[245] |
36 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [246] | 3.57[247] | 2.70[248] | 2.88[249] | 2.62[250] | 4.07[251] | -0.39[252] |
37 | SEC61A1 | Protein transport protein Sec61 subunit alpha isoform 1 | [253] | 3.51[254] | 3.41[255] | 3.47[256] | 2.79[257] | 3.26[258] | 1.27[259] |
38 | PSMC1 | 26S proteasome regulatory subunit 4 | [260] | 1.90[261] | 1.90[262] | 1.36[263] | 2.81[264] | 2.48[265] | -1.23[266] |
39 | PSMA1 | Proteasome subunit alpha type-1 | [267] | 2.08[268] | 2.41[269] | 2.58[270] | 2.38[271] | 2.04[272] | -0.74[273] |
40 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [274] | 3.70[275] | 3.65[276] | 4.78[277] | 2.46[278] | 3.40[279] | -0.51[280] |
41 | PSMC5 | 26S proteasome regulatory subunit 8 | [281] | 2.40[282] | 2.24[283] | 2.42[284] | 1.79[285] | 2.36[286] | -0.97[287] |
42 | S100A1 | Protein S100-A1 | [288] | 1.08[289] | 2.37[290] | -3.44[291] | -5.27[292] | -6.32[293] | -10.12[294] |
43 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [295] | 2.80[296] | 2.23[297] | 2.93[298] | 2.32[299] | 2.70[300] | -1.26[301] |
44 | PSMB8 | Proteasome subunit beta type-8 | [302] | 0.40[303] | -0.25[304] | -7.36[305] | 2.30[306] | 1.14[307] | -1.94[308] |
45 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [309] | 1.97[310] | 2.52[311] | 2.89[312] | 2.19[313] | 2.37[314] | -1.40[315] |
46 | PSMC4 | 26S proteasome regulatory subunit 6B | [316] | 2.40[317] | 2.37[318] | 2.41[319] | 1.82[320] | 2.08[321] | -0.92[322] |
47 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [323] | 1.25[324] | 1.67[325] | 0.69[326] | 1.19[327] | 2.15[328] | -1.51[329] |
48 | SEC22B | Vesicle-trafficking protein SEC22b | [330] | 1.50[331] | 1.68[332] | 1.66[333] | 2.32[334] | 2.95[335] | -0.28[336] |
49 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [337] | 2.44[338] | 2.50[339] | 3.10[340] | 2.25[341] | 1.91[342] | -1.32[343] |
50 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [344] | 1.62[345] | 1.64[346] | 1.44[347] | 1.87[348] | 2.09[349] | -1.40[350] |
51 | PSMC6 | 26S proteasome regulatory subunit 10B | [351] | 1.92[352] | 3.44[353] | 2.36[354] | 2.23[355] | 2.31[356] | -0.75[357] |
52 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [358] | 2.80[359] | 2.36[360] | 3.06[361] | 2.63[362] | 2.94[363] | 0.08[364] |
53 | PSMC2 | 26S proteasome regulatory subunit 7 | [365] | 2.56[366] | 2.90[367] | 2.78[368] | 3.03[369] | 3.01[370] | 0.13[371] |
54 | S100A9 | Protein S100-A9 | [372] | -3.15[373] | -5.58[374] | -3.53[375] | -5.73[376] | -6.13[377] | -1.80[378] |
55 | PSME3 | Proteasome activator complex subunit 3 | [379] | 3.78[380] | 3.45[381] | 3.23[382] | 3.06[383] | 3.47[384] | -0.31[385] |
56 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [386] | 3.54[387] | 3.81[388] | 3.79[389] | 3.86[390] | 4.02[391] | 0.88[392] |
57 | IKBKG | NF-kappa-B essential modulator | [393] | 2.13[394] | 2.32[395] | 0.16[396] | 2.14[397] | 1.05[398] | -0.45[399] |
58 | TAPBP | Tapasin | [400] | 2.75[401] | 2.11[402] | 1.41[403] | 3.07[404] | 2.83[405] | 1.20[406] |
59 | PSMB10 | Proteasome subunit beta type-10 | [407] | 0.82[408] | 1.36[409] | -0.42[410] | 1.65[411] | 0.64[412] | -1.27[413] |
60 | VAMP3 | Vesicle-associated membrane protein 3 | [414] | 3.25[415] | 3.84[416] | 3.12[417] | 3.71[418] | 3.39[419] | -0.87[420] |
61 | PSMA5 | Proteasome subunit alpha type-5 | [421] | 3.87[422] | 4.24[423] | 3.91[424] | 3.91[425] | 3.63[426] | 0.72[427] |
62 | PSMF1 | Proteasome inhibitor PI31 subunit | [428] | 4.25[429] | 4.24[430] | 3.15[431] | 2.92[432] | 2.83[433] | 0.66[434] |
63 | SNAP23 | Synaptosomal-associated protein 23 | [435] | 2.99[436] | 3.07[437] | 2.42[438] | 2.94[439] | 2.88[440] | -0.48[441] |
64 | PSMB2 | Proteasome subunit beta type-2 | [442] | 4.03[443] | 3.71[444] | 4.20[445] | 4.22[446] | 4.35[447] | 1.21[448] |
65 | ITGAV | Integrin alpha-V | [449] | 4.57[450] | 4.41[451] | 3.84[452] | 5.27[453] | 5.28[454] | 0.58[455] |
66 | ITGB5 | Integrin beta-5 | [456] | 4.54[457] | 4.68[458] | 3.74[459] | 4.06[460] | 4.33[461] | 0.38[462] |
67 | PSMB9 | Proteasome subunit beta type-9 | [463] | 0.03[464] | -2.65[465] | -4.85[466] | 3.47[467] | 1.35[468] | -1.69[469] |
68 | CYBA | Cytochrome b-245 light chain | [470] | 4.51[471] | 4.60[472] | 3.58[473] | 3.20[474] | 3.22[475] | -1.27[476] |
69 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [477] | 2.41[478] | 2.84[479] | 1.96[480] | 2.09[481] | 2.68[482] | -0.46[483] |
70 | STX4 | Syntaxin-4 | [484] | 1.84[485] | 2.00[486] | 2.11[487] | 1.17[488] | 1.55[489] | -1.99[490] |
71 | MYD88 | Myeloid differentiation primary response protein MyD88 | [491] | 2.84[492] | 2.94[493] | 2.46[494] | 1.95[495] | 2.38[496] | 0.94[497] |
72 | NCF2 | Neutrophil cytosol factor 2 | [498] | 1.21[499] | -1.44[500] | -5.12[501] | 0.11[502] | -6.39[503] | -2.27[504] |
73 | TAP1 | Antigen peptide transporter 1 | [505] | 2.90[506] | 1.93[507] | -1.69[508] | 4.58[509] | 3.07[510] | -0.52[511] |
74 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [512] | 2.96[513] | 3.23[514] | 3.36[515] | 3.77[516] | 3.24[517] | -0.48[518] |
75 | CTSS | Cathepsin S | [519] | 0.48[520] | 1.17[521] | -1.06[522] | 2.07[523] | -0.64[524] | 0.81[525] |
76 | TAP2 | Antigen peptide transporter 2 | [526] | 3.38[527] | 2.12[528] | 0.71[529] | 5.00[530] | 4.05[531] | -0.25[532] |
77 | PSME4 | Proteasome activator complex subunit 4 | [533] | 4.49[534] | 5.35[535] | 5.45[536] | 4.32[537] | 4.44[538] | 1.79[539] |
78 | HLA-F | HLA class I histocompatibility antigen, alpha chain F | [540] | 0.58[541] | -0.84[542] | -4.89[543] | 4.28[544] | 2.52[545] | 0.17[546] |
79 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [547] | 3.38[548] | 2.88[549] | 4.55[550] | 4.15[551] | 4.38[552] | 0.97[553] |
80 | S100A8 | Protein S100-A8 | [554] | [555] | [556] | [557] | -6.49[558] | [559] | 0.20[560] |
81 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [561] | 3.93[562] | 5.19[563] | 5.24[564] | 3.64[565] | 4.58[566] | 1.66[567] |
82 | HLA-G | HLA class I histocompatibility antigen, alpha chain G | [568] | 0.01[569] | -0.96[570] | -5.56[571] | 1.66[572] | -4.33[573] | -3.65[574] |
83 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [575] | 3.54[576] | 3.65[577] | 3.84[578] | 3.25[579] | 3.47[580] | 1.33[581] |
84 | LY96 | Lymphocyte antigen 96 | [582] | 0.37[583] | 0.02[584] | -6.30[585] | 1.63[586] | -1.87[587] | -1.21[588] |
85 | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein | [589] | 2.89[590] | 2.89[591] | 3.09[592] | 3.27[593] | 2.22[594] | 0.42[595] |
86 | SEC61A2 | Protein transport protein Sec61 subunit alpha isoform 2 | [596] | 3.40[597] | 3.15[598] | 1.88[599] | 4.45[600] | 4.16[601] | 1.04[602] |
87 | CD36 | Platelet glycoprotein 4 | [603] | 4.36[604] | 3.72[605] | -1.27[606] | 6.17[607] | -2.70[608] | 3.23[609] |
88 | NCF1 | Neutrophil cytosol factor 1 | [610] | -4.14[611] | -6.15[612] | [613] | [614] | -6.18[615] | -2.65[616] |
89 | TLR2 | Toll-like receptor 2 | [617] | -0.52[618] | 0.94[619] | -5.98[620] | -1.98[621] | 4.90[622] | 1.39[623] |
90 | CYBB | Cytochrome b-245 heavy chain | [624] | [625] | [626] | -7.07[627] | -1.48[628] | -6.91[629] | 3.20[630] |
91 | MRC1 | Macrophage mannose receptor 1 | [631] | [632] | -5.78[633] | [634] | -4.09[635] | -5.81[636] | 1.70[637] |
92 | LNPEP | Leucyl-cystinyl aminopeptidase | [638] | 4.03[639] | 3.69[640] | 3.69[641] | 5.04[642] | 4.87[643] | 3.22[644] |
93 | NCF4 | Neutrophil cytosol factor 4 | [645] | -2.74[646] | -5.02[647] | [648] | -5.06[649] | [650] | 1.06[651] |
94 | TLR4 | Toll-like receptor 4 | [652] | 3.29[653] | -1.81[654] | -2.62[655] | -2.11[656] | 8.44[657] | 4.62[658] |
95 | TLR1 | Toll-like receptor 1 | [659] | -0.34[660] | [661] | -3.87[662] | 2.59[663] | 3.90[664] | 2.21[665] |
96 | FCGR1A | High affinity immunoglobulin gamma Fc receptor I | [666] | [667] | [668] | [669] | -3.92[670] | [671] | -0.37[672] |
97 | BTK | Tyrosine-protein kinase BTK | [673] | -4.36[674] | [675] | 2.61[676] | -0.02[677] | -2.12[678] | 1.98[679] |
98 | FCGR1B | High affinity immunoglobulin gamma Fc receptor IB | [680] | [681] | [682] | -4.01[683] | [684] | -1.54[685] | -0.61[686] |
99 | TLR6 | Toll-like receptor 6 | [687] | 3.81[688] | 3.96[689] | 3.28[690] | 5.29[691] | 5.50[692] | 2.89[693] |
100 | MRC2 | C-type mannose receptor 2 | [694] | 3.30[695] | 1.42[696] | 3.61[697] | 11.89[698] | 12.09[699] | 4.00[700] |
101 | PSMB11 | Proteasome subunit beta type-11 | [701] | [702] | [703] | [704] | [705] | [706] | [707] |
102 | CTSV | Cathepsin L2 | [708] | [709] | [710] | [711] | [712] | [713] | [714] |
103 | CD207 | C-type lectin domain family 4 member K | [715] | [716] | [717] | [718] | [719] | [720] | [721] |
104 | CTSL | Cathepsin L1 | [722] | [723] | [724] | [725] | [726] | [727] | [728] |
105 | PSMA8 | Proteasome subunit alpha type-7-like | [729] | [730] | [731] | [732] | [733] | [734] | [735] |
106 | SEM1 | Putative protein SEM1, isoform 2 | [736] | [737] | [738] | [739] | [740] | [741] | [742] |