REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SCP2 Non-specific lipid-transfer protein [1] -2.17[2] -1.53[3] -1.60[4] -1.45[5] -1.62[6] -0.74[7]
2 ACSL1 Long-chain-fatty-acid--CoA ligase 1 [8] -0.36[9] -3.31[10] -3.02[11] -2.97[12] 0.18[13] 1.18[14]
3 ACAA1 3-ketoacyl-CoA thiolase, peroxisomal [15] -0.79[16] 0.21[17] -1.99[18] -2.35[19] -2.07[20] -0.94[21]
4 HSD17B4 Peroxisomal multifunctional enzyme type 2 [22] 0.23[23] 0.10[24] -0.48[25] -0.01[26] 0.64[27] -0.31[28]
5 ELOVL5 Elongation of very long chain fatty acids protein 5 [29] 0.32[30] -0.03[31] 0.46[32] 1.70[33] 1.13[34] -2.06[35]
6 ELOVL1 Elongation of very long chain fatty acids protein 1 [36] 1.47[37] 0.44[38] -0.20[39] 1.52[40] 0.88[41] -2.86[42]
7 FADS2 Fatty acid desaturase 2 [43] 0.16[44] 1.13[45] 3.05[46] 2.31[47] -0.19[48] -1.49[49]
8 FADS1 Fatty acid desaturase 1 [50] 2.04[51] 2.64[52] 3.66[53] 2.50[54] 2.23[55] 0.07[56]
9 ELOVL2 Elongation of very long chain fatty acids protein 2 [57] 1.66[58] 2.98[59] 1.36[60] 0.11[61] -1.94[62] -0.90[63]
10 ACOX1 Peroxisomal acyl-coenzyme A oxidase 1 [64] 2.59[65] 2.54[66] 1.71[67] 1.55[68] 1.19[69] 2.00[70]
11 ACOT8 Acyl-coenzyme A thioesterase 8 [71] 0.72[72] 0.71[73] 0.43[74] 1.03[75] 0.51[76] -1.94[77]
12 ABCD1 ATP-binding cassette sub-family D member 1 [78] 4.50[79] 3.17[80] 0.70[81] 3.45[82] 2.52[83] -0.15[84]
13 ELOVL3 Elongation of very long chain fatty acids protein 3 [85] 4.80[86] 3.72[87] 3.60[88] 2.06[89] 6.01[90] [91]
[1]
ref_hepatocyte SCP2
Mean 227
Standard deviation 2.8e+02
Values 1.4e+02 77 9.1 2e+02 7.1e+02
[2]
HepG2 SCP2
Mean 35
Standard deviation 12
Values 27 43
[3]
HepG2.C3A SCP2
Mean 68.2
Standard deviation 19
Values 55 82
[4]
HuH.7 SCP2
Mean 78.3
Standard deviation 13
Values 83 63 89
[5]
SNU475 SCP2
Mean 38.6
Standard deviation 10
Values 46 32
[6]
THLE SCP2
Mean 38.9
Standard deviation 1.4
Values 40 38
[7]
liver SCP2
Mean 407
Standard deviation 2e+02
Values 6.5e+02 2.1e+02 4.9e+02 2.8e+02
[8]
ref_hepatocyte ACSL1
Mean 173
Standard deviation 2.2e+02
Values 17 17 13 3.2e+02 5e+02
[9]
HepG2 ACSL1
Mean 93.9
Standard deviation 14
Values 1e+02 84
[10]
HepG2.C3A ACSL1
Mean 15.2
Standard deviation 4.9
Values 19 12
[11]
HuH.7 ACSL1
Mean 22.4
Standard deviation 13
Values 15 38 14
[12]
SNU475 ACSL1
Mean 10.3
Standard deviation 0.5
Values 9.9 11
[13]
THLE ACSL1
Mean 103
Standard deviation 35
Values 1.3e+02 78
[14]
liver ACSL1
Mean 1.18e+03
Standard deviation 2.6e+02
Values 9.5e+02 1.1e+03 1.1e+03 1.6e+03
[15]
ref_hepatocyte ACAA1
Mean 118
Standard deviation 1e+02
Values 71 41 25 2.1e+02 2.5e+02
[16]
HepG2 ACAA1
Mean 47.6
Standard deviation 17
Values 35 60
[17]
HepG2.C3A ACAA1
Mean 119
Standard deviation 20
Values 1.3e+02 1.1e+02
[18]
HuH.7 ACAA1
Mean 31.3
Standard deviation 4
Values 27 32 35
[19]
SNU475 ACAA1
Mean 10.8
Standard deviation 2.1
Values 12 9.3
[20]
THLE ACAA1
Mean 14.9
Standard deviation 1.6
Values 14 16
[21]
liver ACAA1
Mean 185
Standard deviation 78
Values 2.5e+02 1.2e+02 2.5e+02 1.2e+02
[22]
ref_hepatocyte HSD17B4
Mean 85.8
Standard deviation 51
Values 1.2e+02 57 11 1.1e+02 1.3e+02
[23]
HepG2 HSD17B4
Mean 70.1
Standard deviation 24
Values 53 87
[24]
HepG2.C3A HSD17B4
Mean 80.1
Standard deviation 0.22
Values 80 80
[25]
HuH.7 HSD17B4
Mean 64.3
Standard deviation 5.5
Values 68 58 67
[26]
SNU475 HSD17B4
Mean 39.5
Standard deviation 6.9
Values 44 35
[27]
THLE HSD17B4
Mean 70.3
Standard deviation 2.4
Values 69 72
[28]
liver HSD17B4
Mean 208
Standard deviation 20
Values 1.9e+02 2.2e+02 2.3e+02 1.9e+02
[29]
ref_hepatocyte ELOVL5
Mean 56.8
Standard deviation 44
Values 1.2e+02 80 33 23 24
[30]
HepG2 ELOVL5
Mean 49.5
Standard deviation 3.3
Values 52 47
[31]
HepG2.C3A ELOVL5
Mean 48.2
Standard deviation 12
Values 56 40
[32]
HuH.7 ELOVL5
Mean 81.7
Standard deviation 21
Values 81 1e+02 61
[33]
SNU475 ELOVL5
Mean 86.1
Standard deviation 20
Values 1e+02 72
[34]
THLE ELOVL5
Mean 65.5
Standard deviation 8
Values 60 71
[35]
liver ELOVL5
Mean 40.8
Standard deviation 18
Values 29 37 68 30
[36]
ref_hepatocyte ELOVL1
Mean 24.3
Standard deviation 16
Values 9.4 40 42 20 10
[37]
HepG2 ELOVL1
Mean 46.8
Standard deviation 3.4
Values 44 49
[38]
HepG2.C3A ELOVL1
Mean 28.6
Standard deviation 0.69
Values 28 29
[39]
HuH.7 ELOVL1
Mean 22.2
Standard deviation 4.3
Values 25 17 24
[40]
SNU475 ELOVL1
Mean 32.3
Standard deviation 1.1
Values 33 32
[41]
THLE ELOVL1
Mean 23.6
Standard deviation 3.4
Values 21 26
[42]
liver ELOVL1
Mean 10.1
Standard deviation 8.1
Values 17 2.8 17 3.2
[43]
ref_hepatocyte FADS2
Mean 21
Standard deviation 10
Values 8.2 16 24 21 36
[44]
HepG2 FADS2
Mean 16.3
Standard deviation 4.9
Values 13 20
[45]
HepG2.C3A FADS2
Mean 39.8
Standard deviation 12
Values 49 31
[46]
HuH.7 FADS2
Mean 181
Standard deviation 24
Values 2.1e+02 1.7e+02 1.6e+02
[47]
SNU475 FADS2
Mean 48.4
Standard deviation 26
Values 67 30
[48]
THLE FADS2
Mean 9.67
Standard deviation 2.5
Values 7.9 11
[49]
liver FADS2
Mean 22.5
Standard deviation 17
Values 3.1 41 15 31
[50]
ref_hepatocyte FADS1
Mean 17.1
Standard deviation 5.7
Values 21 20 22 11 10
[51]
HepG2 FADS1
Mean 48.8
Standard deviation 2.8
Values 51 47
[52]
HepG2.C3A FADS1
Mean 92.7
Standard deviation 11
Values 1e+02 85
[53]
HuH.7 FADS1
Mean 225
Standard deviation 35
Values 2.4e+02 2.5e+02 1.9e+02
[54]
SNU475 FADS1
Mean 44.8
Standard deviation 3.1
Values 47 43
[55]
THLE FADS1
Mean 42.2
Standard deviation 8
Values 37 48
[56]
liver FADS1
Mean 53.9
Standard deviation 20
Values 27 60 75 53
[57]
ref_hepatocyte ELOVL2
Mean 11.4
Standard deviation 14
Values 36 6.9 0.76 3.6 10
[58]
HepG2 ELOVL2
Mean 25.1
Standard deviation 4.4
Values 22 28
[59]
HepG2.C3A ELOVL2
Mean 78.4
Standard deviation 3.4
Values 76 81
[60]
HuH.7 ELOVL2
Mean 30.6
Standard deviation 8.3
Values 28 40 24
[61]
SNU475 ELOVL2
Mean 5.74
Standard deviation 0.25
Values 5.9 5.6
[62]
THLE ELOVL2
Mean 1.56
Standard deviation 0.62
Values 2 1.1
[63]
liver ELOVL2
Mean 18.3
Standard deviation 11
Values 32 7.1 11 24
[64]
ref_hepatocyte ACOX1
Mean 11.2
Standard deviation 8.5
Values 15 4.5 2.3 11 23
[65]
HepG2 ACOX1
Mean 46.9
Standard deviation 9
Values 41 53
[66]
HepG2.C3A ACOX1
Mean 56.3
Standard deviation 2.2
Values 58 55
[67]
HuH.7 ACOX1
Mean 38.2
Standard deviation 5
Values 43 33 38
[68]
SNU475 ACOX1
Mean 15.2
Standard deviation 4.1
Values 18 12
[69]
THLE ACOX1
Mean 13.4
Standard deviation 1.8
Values 12 15
[70]
liver ACOX1
Mean 134
Standard deviation 77
Values 63 1.8e+02 75 2.2e+02
[71]
ref_hepatocyte ACOT8
Mean 9.09
Standard deviation 5.1
Values 7.6 4.2 4.6 14 15
[72]
HepG2 ACOT8
Mean 10.5
Standard deviation 0.047
Values 10 10
[73]
HepG2.C3A ACOT8
Mean 12.9
Standard deviation 0.35
Values 13 13
[74]
HuH.7 ACOT8
Mean 12.8
Standard deviation 3.6
Values 14 8.8 16
[75]
SNU475 ACOT8
Mean 8.62
Standard deviation 1.7
Values 9.8 7.4
[76]
THLE ACOT8
Mean 6.83
Standard deviation 0.25
Values 6.7 7
[77]
liver ACOT8
Mean 7.1
Standard deviation 3.2
Values 9.8 5.3 9.8 3.5
[78]
ref_hepatocyte ABCD1
Mean 2.32
Standard deviation 1.2
Values 4.2 1.1 2.6 2.4 1.3
[79]
HepG2 ABCD1
Mean 36.5
Standard deviation 6.2
Values 41 32
[80]
HepG2.C3A ABCD1
Mean 18.2
Standard deviation 4.3
Values 21 15
[81]
HuH.7 ABCD1
Mean 3.94
Standard deviation 0.8
Values 3.7 4.8 3.3
[82]
SNU475 ABCD1
Mean 11.8
Standard deviation 4.2
Values 15 8.8
[83]
THLE ABCD1
Mean 6.97
Standard deviation 0.6
Values 6.5 7.4
[84]
liver ABCD1
Mean 6.26
Standard deviation 1.8
Values 5.9 7.6 3.9 7.6
[85]
ref_hepatocyte ELOVL3
Mean 0.0431
Standard deviation 0.096
Values 0 0 0 0.22 0
[86]
HepG2 ELOVL3
Mean 0.839
Standard deviation 0.046
Values 0.87 0.81
[87]
HepG2.C3A ELOVL3
Mean 0.494
Standard deviation 0.12
Values 0.41 0.58
[88]
HuH.7 ELOVL3
Mean 0.547
Standard deviation 0.3
Values 0.49 0.28 0.87
[89]
SNU475 ELOVL3
Mean 0.0834
Standard deviation 0.033
Values 0.06 0.11
[90]
THLE ELOVL3
Mean 1.46
Standard deviation 0.1
Values 1.5 1.4
[91]
liver ELOVL3
Mean 0
Standard deviation 0
Values 0 0 0 0