REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AKT1 RAC-alpha serine/threonine-protein kinase [1] -0.04[2] -0.38[3] -1.33[4] -0.46[5] -0.50[6] -0.67[7]
2 RPS6KB2 Ribosomal protein S6 kinase beta-2 [8] [9] [10] [11] [12] [13] [14]
3 AKT2 RAC-beta serine/threonine-protein kinase [15] 0.84[16] 1.00[17] 1.26[18] 0.45[19] 0.17[20] 0.70[21]
4 FOXO3 Forkhead box protein O3 [22] 0.34[23] 0.31[24] 1.08[25] -0.01[26] 1.16[27] 1.90[28]
5 CREB1 Cyclic AMP-responsive element-binding protein 1 [29] 1.60[30] 2.65[31] 3.27[32] 2.13[33] 2.01[34] 1.91[35]
6 FOXO1 Forkhead box protein O1 [36] 1.57[37] 1.13[38] 1.39[39] 0.77[40] 2.72[41] 2.66[42]
7 FOXO4 Forkhead box protein O4 [43] 0.61[44] 0.90[45] 0.86[46] -0.24[47] -0.10[48] -1.12[49]
8 NR4A1 Nuclear receptor subfamily 4 group A member 1 [50] 1.10[51] 1.53[52] 1.80[53] -0.26[54] 0.76[55] 0.10[56]
9 AKT3 RAC-gamma serine/threonine-protein kinase [57] -1.96[58] -4.63[59] -3.82[60] 5.43[61] 4.32[62] 3.18[63]
10 FOXO6 Forkhead box protein O6 [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[2]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[3]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[4]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[5]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[6]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[7]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[8]
ref_hepatocyte RPS6KB2
Mean 17
Standard deviation 4.8
Values 17 25 15 15 13
[9]
HepG2 RPS6KB2
Missing
[10]
HepG2.C3A RPS6KB2
Missing
[11]
HuH.7 RPS6KB2
Missing
[12]
SNU475 RPS6KB2
Missing
[13]
THLE RPS6KB2
Missing
[14]
liver RPS6KB2
Missing
[15]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[16]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[17]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[18]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[19]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[20]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[21]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[22]
ref_hepatocyte FOXO3
Mean 2.79
Standard deviation 0.38
Values 3.3 2.7 2.3 2.8 2.9
[23]
HepG2 FOXO3
Mean 8.44
Standard deviation 1
Values 7.7 9.2
[24]
HepG2.C3A FOXO3
Mean 8
Standard deviation 2.4
Values 9.7 6.3
[25]
HuH.7 FOXO3
Mean 11.9
Standard deviation 3.6
Values 13 15 7.9
[26]
SNU475 FOXO3
Mean 6.76
Standard deviation 0.76
Values 7.3 6.2
[27]
THLE FOXO3
Mean 17.9
Standard deviation 3.1
Values 16 20
[28]
liver FOXO3
Mean 20
Standard deviation 5.5
Values 24 21 12 23
[29]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 3.7 2.1 1.5 0.96 0.81
[30]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 11 15
[31]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 24 28
[32]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 38 36 31
[33]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[34]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[35]
liver CREB1
Mean 13
Standard deviation 3.1
Values 12 16 9.3 15
[36]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 0.71 1.7 2 1.9 2.6
[37]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 11 14
[38]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 10 7.9
[39]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 10 10 7.6
[40]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 8.6 6
[41]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[42]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 25 19 13 29
[43]
ref_hepatocyte FOXO4
Mean 1.56
Standard deviation 0.85
Values 2.8 1.6 0.42 1.7 1.3
[44]
HepG2 FOXO4
Mean 5.71
Standard deviation 1.3
Values 6.6 4.8
[45]
HepG2.C3A FOXO4
Mean 6.69
Standard deviation 3.6
Values 9.2 4.2
[46]
HuH.7 FOXO4
Mean 5.72
Standard deviation 1.5
Values 5.1 7.5 4.6
[47]
SNU475 FOXO4
Mean 3.21
Standard deviation 1.1
Values 4 2.4
[48]
THLE FOXO4
Mean 4.17
Standard deviation 0.02
Values 4.2 4.2
[49]
liver FOXO4
Mean 1.37
Standard deviation 1.1
Values 0.54 2 0.33 2.6
[50]
ref_hepatocyte NR4A1
Mean 0.973
Standard deviation 0.84
Values 0.53 0.14 1.1 2.3 0.73
[51]
HepG2 NR4A1
Mean 4.99
Standard deviation 1.2
Values 5.9 4.1
[52]
HepG2.C3A NR4A1
Mean 6.51
Standard deviation 3.5
Values 9 4
[53]
HuH.7 NR4A1
Mean 6.85
Standard deviation 0.31
Values 7 6.5 7.1
[54]
SNU475 NR4A1
Mean 1.97
Standard deviation 1.2
Values 1.1 2.8
[55]
THLE NR4A1
Mean 4.73
Standard deviation 1.4
Values 5.7 3.7
[56]
liver NR4A1
Mean 1.99
Standard deviation 2
Values 5 0.9 1.2 0.85
[57]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.83 0.16 0.41
[58]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[59]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[60]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[61]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[62]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[63]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 2.8 12 2.3 9.4
[64]
ref_hepatocyte FOXO6
Missing
[65]
HepG2 FOXO6
Missing
[66]
HepG2.C3A FOXO6
Missing
[67]
HuH.7 FOXO6
Missing
[68]
SNU475 FOXO6
Missing
[69]
THLE FOXO6
Missing
[70]
liver FOXO6
Missing