REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -0.98[1] | -0.55[2] | -1.57[3] | -2.05[4] | -2.51[5] | -0.99[6] | |
2 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [7] | 1.24[8] | 1.50[9] | 0.87[10] | 1.04[11] | 0.64[12] | -0.64[13] |
3 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [14] | -0.37[15] | -0.38[16] | -0.20[17] | -0.61[18] | -0.75[19] | -1.00[20] |
4 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.47[21] | -3.94[22] | -4.40[23] | -4.05[24] | -3.43[25] | -3.75[26] | |
5 | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | [27] | 0.30[28] | -0.52[29] | -0.51[30] | -0.41[31] | 0.46[32] | 0.41[33] |
6 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.52[34] | -7.21[35] | 0.58[36] | 1.64[37] | 1.54[38] | 1.08[39] | |
7 | GNAI1 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | [40] | -1.42[41] | -2.11[42] | -0.13[43] | 0.97[44] | 0.15[45] | 1.43[46] |
8 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [47] | 0.33[48] | 0.61[49] | 1.47[50] | 0.55[51] | 0.47[52] | 1.49[53] |
9 | ADCY6 | Adenylate cyclase type 6 | [54] | 2.28[55] | 2.99[56] | 2.79[57] | 2.26[58] | 2.74[59] | 3.23[60] |
10 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -7.95[61] | -7.71[62] | -7.17[63] | 2.02[64] | 3.15[65] | 2.83[66] | |
11 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.79[67] | 1.68[68] | 2.33[69] | -2.48[70] | -2.05[71] | 0.62[72] | |
12 | ADRA2C | Alpha-2C adrenergic receptor | [73] | 4.25[74] | -1.92[75] | -0.42[76] | -3.48[77] | -5.40[78] | -2.63[79] |
13 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.70[80] | 1.71[81] | 5.35[82] | 1.02[83] | -1.30[84] | -1.95[85] | |
14 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [86] | -0.14[87] | 0.60[88] | 1.44[89] | 2.44[90] | 4.98[91] | 4.69[92] |
15 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -6.05[93] | -6.68[94] | [95] | 2.88[96] | 2.15[97] | 3.38[98] | |
16 | CACNB3 | Voltage-dependent L-type calcium channel subunit beta-3 | [99] | 2.54[100] | -0.32[101] | 4.23[102] | 4.85[103] | 3.82[104] | 1.06[105] |
17 | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha-1D | [106] | -3.49[107] | -0.23[108] | 1.91[109] | -1.71[110] | -4.55[111] | 5.11[112] |
18 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [113] | [114] | [115] | -2.31[116] | -7.18[117] | 0.71[118] | |
19 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.63[119] | 1.45[120] | -0.93[121] | -0.94[122] | -1.45[123] | 0.51[124] | |
20 | CACNB2 | Voltage-dependent L-type calcium channel subunit beta-2 | [125] | 0.24[126] | 2.44[127] | 2.30[128] | 3.33[129] | 1.55[130] | 5.64[131] |
21 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [132] | 1.82[133] | 4.32[134] | 3.46[135] | 0.77[136] | 3.28[137] | -1.08[138] |
22 | ADCY5 | Adenylate cyclase type 5 | [139] | 0.38[140] | 1.62[141] | 2.50[142] | 0.41[143] | 1.33[144] | 6.97[145] |
23 | CACNA2D | Voltage-dependent calcium channel subunit alpha-2/delta-2 | [146] | -1.08[147] | 1.36[148] | 1.78[149] | 0.00[150] | 1.56[151] | 2.43[152] |
24 | ADRA2A | Alpha-2A adrenergic receptor | [153] | -2.92[154] | -1.19[155] | [156] | 1.10[157] | 3.60[158] | 4.59[159] |
25 | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha-1C | [160] | 4.95[161] | 2.70[162] | 5.40[163] | 5.48[164] | 7.51[165] | 8.91[166] |
26 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [167] | [168] | [169] | [170] | [171] | [172] | [173] |
27 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [174] | [175] | [176] | [177] | [178] | [179] | |
28 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [180] | [181] | [182] | [183] | [184] | [185] |