REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 POLE3 DNA polymerase epsilon subunit 3 [1] -1.64[2] -1.93[3] -2.12[4] -1.81[5] -1.26[6] -1.09[7]
2 POLE4 DNA polymerase epsilon subunit 4 [8] -1.90[9] -1.31[10] -5.25[11] -2.38[12] -3.34[13] -1.33[14]
3 RPA2 Replication protein A 32 kDa subunit [15] -2.32[16] -2.39[17] -2.31[18] -1.50[19] -1.91[20] -1.92[21]
4 GMNN Geminin [22] -1.17[23] -0.30[24] -1.32[25] -1.04[26] -1.74[27] -2.01[28]
5 MCM7 DNA replication licensing factor MCM7 [29] 1.06[30] 0.71[31] 1.45[32] 0.53[33] 0.60[34] -0.32[35]
6 MCM3 DNA replication licensing factor MCM3 [36] 1.44[37] 1.15[38] 0.77[39] 0.23[40] 0.83[41] -0.21[42]
7 CDK2 Cyclin-dependent kinase 2 [43] -1.27[44] -1.25[45] -1.36[46] -0.78[47] -0.67[48] -1.71[49]
8 MCM4 DNA replication licensing factor MCM4 [50] 1.21[51] 0.95[52] 1.18[53] 1.24[54] 1.40[55] -0.51[56]
9 MCM5 DNA replication licensing factor MCM5 [57] 0.36[58] 0.08[59] 0.22[60] -0.24[61] 0.20[62] -0.44[63]
10 RPA1 Replication protein A 70 kDa DNA-binding subunit [64] 0.46[65] 0.05[66] -0.17[67] 1.09[68] 0.63[69] 0.48[70]
11 RPA3 Replication protein A 14 kDa subunit [71] -1.23[72] -0.57[73] -0.34[74] -1.66[75] -1.86[76] -0.22[77]
12 ORC4 Origin recognition complex subunit 4 [78] -0.80[79] 0.24[80] -0.53[81] 0.61[82] -0.62[83] 3.45[84]
13 ORC5 Origin recognition complex subunit 5 [85] -1.84[86] -1.64[87] -1.55[88] -0.90[89] -1.62[90] 0.30[91]
14 ORC2 Origin recognition complex subunit 2 [92] -0.40[93] 0.42[94] -0.34[95] -0.45[96] -0.64[97] 0.04[98]
15 CDC6 Cell division control protein 6 homolog [99] 1.00[100] 0.43[101] 0.54[102] 0.81[103] 0.60[104] -1.59[105]
16 ORC6 Origin recognition complex subunit 6 [106] -0.10[107] 0.32[108] -0.94[109] 0.03[110] -0.20[111] -3.22[112]
17 MCM6 DNA replication licensing factor MCM6 [113] 0.34[114] -0.09[115] 1.44[116] 1.66[117] 1.97[118] -0.81[119]
18 MCM2 DNA replication licensing factor MCM2 [120] 2.07[121] 1.37[122] 2.18[123] 1.37[124] 1.90[125] -1.14[126]
19 ORC3 Origin recognition complex subunit 3 [127] -0.77[128] 0.29[129] -0.06[130] -0.21[131] 0.27[132] 0.73[133]
20 CDC45 Cell division control protein 45 homolog [134] 0.34[135] 0.15[136] 0.32[137] 0.50[138] 0.36[139] -2.43[140]
21 POLA2 DNA polymerase alpha subunit B [141] -0.22[142] -0.72[143] -0.65[144] 0.76[145] 0.58[146] -0.36[147]
22 PRIM1 DNA primase small subunit [148] -0.19[149] 0.99[150] 0.84[151] 0.40[152] 0.51[153] -0.43[154]
23 PRIM2 DNA primase large subunit [155] 0.42[156] 0.08[157] -0.79[158] 0.42[159] 0.19[160] -1.11[161]
24 DBF4 Protein DBF4 homolog A [162] -0.36[163] 1.13[164] 0.38[165] 0.83[166] 0.61[167] 0.01[168]
25 MCM8 DNA helicase MCM8 [169] 1.34[170] 1.91[171] 0.70[172] 1.85[173] 0.91[174] 0.11[175]
26 ORC1 Origin recognition complex subunit 1 [176] 0.69[177] 0.58[178] 1.60[179] 0.52[180] 0.60[181] -1.63[182]
27 POLE DNA polymerase epsilon catalytic subunit A [183] 2.19[184] 2.67[185] 2.23[186] 1.98[187] 2.51[188] 3.41[189]
28 POLE2 DNA polymerase epsilon subunit 2 [190] -0.16[191] 0.50[192] 1.00[193] 0.40[194] 0.45[195] -0.68[196]
29 CDT1 DNA replication factor Cdt1 [197] 2.38[198] 2.53[199] 3.52[200] 1.78[201] 1.89[202] -1.35[203]
30 CDC7 Cell division cycle 7-related protein kinase [204] -0.36[205] 0.46[206] 0.78[207] 1.66[208] 1.90[209] -0.31[210]
31 POLA1 DNA polymerase alpha catalytic subunit [211] 1.15[212] 1.12[213] 1.19[214] 2.23[215] 1.71[216] 2.15[217]
32 MCM10 Protein MCM10 homolog [218] 1.65[219] 2.15[220] 1.32[221] 2.93[222] 1.98[223] -1.15[224]
33 RPA4 Replication protein A 30 kDa subunit [225] -6.07[226] -5.94[227] [228] -2.49[229] -2.98[230] 2.32[231]
[1]
ref_hepatocyte POLE3
Mean 29.6
Standard deviation 21
Values 23 62 36 15 11
[2]
HepG2 POLE3
Mean 37.9
Standard deviation 13
Values 29 47
[3]
HepG2.C3A POLE3
Mean 30.6
Standard deviation 16
Values 19 42
[4]
HuH.7 POLE3
Mean 36
Standard deviation 15
Values 40 20 48
[5]
SNU475 POLE3
Mean 26.1
Standard deviation 0.99
Values 25 27
[6]
THLE POLE3
Mean 60
Standard deviation 7.2
Values 55 65
[7]
liver POLE3
Mean 14.1
Standard deviation 6.6
Values 15 11 23 7.8
[8]
ref_hepatocyte POLE4
Mean 27.1
Standard deviation 15
Values 28 15 9.6 45 38
[9]
HepG2 POLE4
Mean 28.9
Standard deviation 4.6
Values 26 32
[10]
HepG2.C3A POLE4
Mean 43
Standard deviation 18
Values 30 56
[11]
HuH.7 POLE4
Mean 3.76
Standard deviation 1.5
Values 3.8 2.3 5.3
[12]
SNU475 POLE4
Mean 16.1
Standard deviation 1
Values 17 15
[13]
THLE POLE4
Mean 13
Standard deviation 1.2
Values 12 14
[14]
liver POLE4
Mean 11
Standard deviation 11
Values 24 1.7 18 1.1
[15]
ref_hepatocyte RPA2
Mean 23.6
Standard deviation 12
Values 23 41 28 15 11
[16]
HepG2 RPA2
Mean 19
Standard deviation 3.9
Values 16 22
[17]
HepG2.C3A RPA2
Mean 17.8
Standard deviation 8.2
Values 12 24
[18]
HuH.7 RPA2
Mean 25.2
Standard deviation 11
Values 27 14 35
[19]
SNU475 RPA2
Mean 25.9
Standard deviation 7.9
Values 20 31
[20]
THLE RPA2
Mean 30.6
Standard deviation 2.7
Values 29 33
[21]
liver RPA2
Mean 6.36
Standard deviation 3.6
Values 6.9 4.2 11 3.2
[22]
ref_hepatocyte GMNN
Mean 15.1
Standard deviation 12
Values 37 12 8.5 8.8 8.8
[23]
HepG2 GMNN
Mean 26.9
Standard deviation 11
Values 19 35
[24]
HepG2.C3A GMNN
Mean 48.3
Standard deviation 22
Values 32 64
[25]
HuH.7 GMNN
Mean 32.1
Standard deviation 8.7
Values 31 24 41
[26]
SNU475 GMNN
Mean 22.8
Standard deviation 4.3
Values 20 26
[27]
THLE GMNN
Mean 22
Standard deviation 1
Values 21 23
[28]
liver GMNN
Mean 3.83
Standard deviation 2.8
Values 6.9 1.5 5.5 1.4
[29]
ref_hepatocyte MCM7
Mean 13.4
Standard deviation 7.2
Values 15 25 12 8.9 6.7
[30]
HepG2 MCM7
Mean 112
Standard deviation 0.92
Values 1.1e+02 1.1e+02
[31]
HepG2.C3A MCM7
Mean 86.1
Standard deviation 36
Values 61 1.1e+02
[32]
HuH.7 MCM7
Mean 194
Standard deviation 1.1e+02
Values 2.4e+02 70 2.7e+02
[33]
SNU475 MCM7
Mean 60
Standard deviation 16
Values 49 71
[34]
THLE MCM7
Mean 99
Standard deviation 18
Values 86 1.1e+02
[35]
liver MCM7
Mean 10.9
Standard deviation 2.3
Values 13 8.8 13 9.1
[36]
ref_hepatocyte MCM3
Mean 13
Standard deviation 10
Values 30 15 7.4 7.5 5.1
[37]
HepG2 MCM3
Mean 141
Standard deviation 33
Values 1.2e+02 1.6e+02
[38]
HepG2.C3A MCM3
Mean 113
Standard deviation 52
Values 76 1.5e+02
[39]
HuH.7 MCM3
Mean 117
Standard deviation 69
Values 1.5e+02 38 1.6e+02
[40]
SNU475 MCM3
Mean 47
Standard deviation 14
Values 37 57
[41]
THLE MCM3
Mean 112
Standard deviation 21
Values 97 1.3e+02
[42]
liver MCM3
Mean 11.4
Standard deviation 4
Values 10 12 17 7.2
[43]
ref_hepatocyte CDK2
Mean 12.1
Standard deviation 11
Values 19 28 3.3 5.7 4.6
[44]
HepG2 CDK2
Mean 20
Standard deviation 3.4
Values 18 22
[45]
HepG2.C3A CDK2
Mean 20
Standard deviation 9.1
Values 14 26
[46]
HuH.7 CDK2
Mean 24.9
Standard deviation 12
Values 30 11 33
[47]
SNU475 CDK2
Mean 21.8
Standard deviation 2.6
Values 20 24
[48]
THLE CDK2
Mean 36.9
Standard deviation 5.3
Values 33 41
[49]
liver CDK2
Mean 3.76
Standard deviation 1.3
Values 4.4 2.3 5.2 3.2
[50]
ref_hepatocyte MCM4
Mean 9.18
Standard deviation 8.6
Values 21 15 5.1 2.3 1.9
[51]
HepG2 MCM4
Mean 84.7
Standard deviation 28
Values 65 1e+02
[52]
HepG2.C3A MCM4
Mean 69.6
Standard deviation 44
Values 39 1e+02
[53]
HuH.7 MCM4
Mean 110
Standard deviation 72
Values 1.6e+02 27 1.5e+02
[54]
SNU475 MCM4
Mean 67.3
Standard deviation 15
Values 57 78
[55]
THLE MCM4
Mean 118
Standard deviation 29
Values 98 1.4e+02
[56]
liver MCM4
Mean 6.6
Standard deviation 2.7
Values 4.8 8.8 9 3.8
[57]
ref_hepatocyte MCM5
Mean 8.67
Standard deviation 4.6
Values 8.3 17 7.2 6.4 4.9
[58]
HepG2 MCM5
Mean 44.4
Standard deviation 5.9
Values 40 49
[59]
HepG2.C3A MCM5
Mean 36.1
Standard deviation 17
Values 24 48
[60]
HuH.7 MCM5
Mean 53.6
Standard deviation 30
Values 74 20 67
[61]
SNU475 MCM5
Mean 22.8
Standard deviation 3.6
Values 20 25
[62]
THLE MCM5
Mean 48.5
Standard deviation 18
Values 36 61
[63]
liver MCM5
Mean 6.52
Standard deviation 2.3
Values 4.8 8.4 8.7 4.2
[64]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 9.2 15 5.5 5.3 6.7
[65]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 39 51
[66]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 26 41
[67]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 47 23 48
[68]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 55 54
[69]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[70]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 12 12 14 9.5
[71]
ref_hepatocyte RPA3
Mean 8.22
Standard deviation 4.8
Values 6.2 7.6 1.9 11 15
[72]
HepG2 RPA3
Mean 14.1
Standard deviation 4
Values 11 17
[73]
HepG2.C3A RPA3
Mean 21.8
Standard deviation 13
Values 13 31
[74]
HuH.7 RPA3
Mean 34.5
Standard deviation 16
Values 35 18 50
[75]
SNU475 RPA3
Mean 8.05
Standard deviation 1.5
Values 9.1 7
[76]
THLE RPA3
Mean 11
Standard deviation 2.9
Values 8.9 13
[77]
liver RPA3
Mean 7.22
Standard deviation 6.1
Values 13 2.4 12 1.4
[78]
ref_hepatocyte ORC4
Mean 7.34
Standard deviation 1.8
Values 9.4 4.6 8.6 6.9 7.2
[79]
HepG2 ORC4
Mean 16.9
Standard deviation 4.9
Values 13 20
[80]
HepG2.C3A ORC4
Mean 34.1
Standard deviation 8.3
Values 28 40
[81]
HuH.7 ORC4
Mean 27
Standard deviation 4
Values 28 31 23
[82]
SNU475 ORC4
Mean 34.9
Standard deviation 3.4
Values 32 37
[83]
THLE ORC4
Mean 23.3
Standard deviation 2.6
Values 25 21
[84]
liver ORC4
Mean 81.8
Standard deviation 55
Values 38 1.4e+02 33 1.2e+02
[85]
ref_hepatocyte ORC5
Mean 6.5
Standard deviation 1.9
Values 3.5 7.8 7.3 8.2 5.7
[86]
HepG2 ORC5
Mean 7.28
Standard deviation 2.2
Values 5.8 8.8
[87]
HepG2.C3A ORC5
Mean 8.23
Standard deviation 4.9
Values 4.8 12
[88]
HuH.7 ORC5
Mean 11.8
Standard deviation 2.5
Values 13 9 14
[89]
SNU475 ORC5
Mean 10.8
Standard deviation 1.4
Values 9.8 12
[90]
THLE ORC5
Mean 10.3
Standard deviation 0.9
Values 9.6 11
[91]
liver ORC5
Mean 8.17
Standard deviation 1.7
Values 7.3 8.1 11 6.7
[92]
ref_hepatocyte ORC2
Mean 5.18
Standard deviation 5.6
Values 14 7.4 2.6 0.85 0.94
[93]
HepG2 ORC2
Mean 15.7
Standard deviation 4.5
Values 13 19
[94]
HepG2.C3A ORC2
Mean 27.2
Standard deviation 6.2
Values 23 32
[95]
HuH.7 ORC2
Mean 21.7
Standard deviation 4
Values 24 17 24
[96]
SNU475 ORC2
Mean 11.7
Standard deviation 1.6
Values 13 11
[97]
THLE ORC2
Mean 16.1
Standard deviation 1.1
Values 15 17
[98]
liver ORC2
Mean 5.45
Standard deviation 2.1
Values 6.1 5.5 2.6 7.7
[99]
ref_hepatocyte CDC6
Mean 4.53
Standard deviation 4.6
Values 11 8.2 1.9 1.2 0.8
[100]
HepG2 CDC6
Mean 36.3
Standard deviation 14
Values 26 46
[101]
HepG2.C3A CDC6
Mean 24
Standard deviation 17
Values 12 36
[102]
HuH.7 CDC6
Mean 35
Standard deviation 18
Values 43 15 47
[103]
SNU475 CDC6
Mean 24.6
Standard deviation 9.5
Values 18 31
[104]
THLE CDC6
Mean 33.3
Standard deviation 6.1
Values 29 38
[105]
liver CDC6
Mean 1.54
Standard deviation 0.85
Values 0.42 2.4 2 1.4
[106]
ref_hepatocyte ORC6
Mean 4.29
Standard deviation 5.9
Values 14 6.1 0.59 0.53 0.4
[107]
HepG2 ORC6
Mean 16
Standard deviation 4.8
Values 13 19
[108]
HepG2.C3A ORC6
Mean 21.1
Standard deviation 15
Values 11 32
[109]
HuH.7 ORC6
Mean 11.8
Standard deviation 5.5
Values 12 6.2 17
[110]
SNU475 ORC6
Mean 13.6
Standard deviation 0.87
Values 13 14
[111]
THLE ORC6
Mean 18.1
Standard deviation 2.6
Values 16 20
[112]
liver ORC6
Mean 0.47
Standard deviation 0.32
Values 0.26 0.46 0.92 0.24
[113]
ref_hepatocyte MCM6
Mean 4.29
Standard deviation 3.5
Values 3.7 10 4.3 1.8 1.5
[114]
HepG2 MCM6
Mean 21.7
Standard deviation 9.4
Values 15 28
[115]
HepG2.C3A MCM6
Mean 15.9
Standard deviation 9.1
Values 9.5 22
[116]
HuH.7 MCM6
Mean 61.7
Standard deviation 38
Values 84 18 83
[117]
SNU475 MCM6
Mean 42.1
Standard deviation 6.7
Values 37 47
[118]
THLE MCM6
Mean 81.8
Standard deviation 9.3
Values 75 88
[119]
liver MCM6
Mean 2.49
Standard deviation 1
Values 1.7 3.7 2.9 1.6
[120]
ref_hepatocyte MCM2
Mean 4.21
Standard deviation 3.2
Values 9.4 4.9 3.2 1.5 2.1
[121]
HepG2 MCM2
Mean 70.6
Standard deviation 14
Values 61 81
[122]
HepG2.C3A MCM2
Mean 42.9
Standard deviation 17
Values 31 55
[123]
HuH.7 MCM2
Mean 101
Standard deviation 57
Values 1.4e+02 36 1.3e+02
[124]
SNU475 MCM2
Mean 33.8
Standard deviation 11
Values 26 42
[125]
THLE MCM2
Mean 76.3
Standard deviation 20
Values 62 91
[126]
liver MCM2
Mean 1.95
Standard deviation 1.4
Values 1.1 4 1.8 0.94
[127]
ref_hepatocyte ORC3
Mean 3.83
Standard deviation 0.95
Values 4.8 3 4.9 3.1 3.3
[128]
HepG2 ORC3
Mean 8.96
Standard deviation 5.2
Values 5.3 13
[129]
HepG2.C3A ORC3
Mean 18.4
Standard deviation 9
Values 12 25
[130]
HuH.7 ORC3
Mean 19.5
Standard deviation 5.8
Values 24 13 21
[131]
SNU475 ORC3
Mean 10.2
Standard deviation 0.75
Values 9.7 11
[132]
THLE ORC3
Mean 22.5
Standard deviation 0.42
Values 23 22
[133]
liver ORC3
Mean 6.5
Standard deviation 1.7
Values 6.9 6.4 8.4 4.3
[134]
ref_hepatocyte CDC45
Mean 2.51
Standard deviation 2.5
Values 3.1 6.6 1.3 1.1 0.37
[135]
HepG2 CDC45
Mean 12.8
Standard deviation 2.7
Values 11 15
[136]
HepG2.C3A CDC45
Mean 11
Standard deviation 7.8
Values 5.4 17
[137]
HuH.7 CDC45
Mean 16.7
Standard deviation 12
Values 20 3.6 26
[138]
SNU475 CDC45
Mean 11
Standard deviation 3.8
Values 8.4 14
[139]
THLE CDC45
Mean 15.7
Standard deviation 2.2
Values 14 17
[140]
liver CDC45
Mean 0.476
Standard deviation 0.53
Values 0.16 0.56 1.2 0
[141]
ref_hepatocyte POLA2
Mean 2.46
Standard deviation 0.96
Values 1.8 2.8 3.9 2.3 1.5
[142]
HepG2 POLA2
Mean 8.49
Standard deviation 2.2
Values 6.9 10
[143]
HepG2.C3A POLA2
Mean 5.87
Standard deviation 3.6
Values 3.3 8.4
[144]
HuH.7 POLA2
Mean 8.32
Standard deviation 5.1
Values 11 2.5 11
[145]
SNU475 POLA2
Mean 12.9
Standard deviation 3.1
Values 11 15
[146]
THLE POLA2
Mean 17.9
Standard deviation 4
Values 15 21
[147]
liver POLA2
Mean 1.96
Standard deviation 0.6
Values 1.2 1.9 2.6 2.2
[148]
ref_hepatocyte PRIM1
Mean 2.43
Standard deviation 1.4
Values 4.4 2.6 0.57 2.6 1.9
[149]
HepG2 PRIM1
Mean 8.54
Standard deviation 0.87
Values 7.9 9.2
[150]
HepG2.C3A PRIM1
Mean 19.1
Standard deviation 8.1
Values 13 25
[151]
HuH.7 PRIM1
Mean 23.1
Standard deviation 6.2
Values 27 16 26
[152]
SNU475 PRIM1
Mean 9.98
Standard deviation 3.1
Values 7.8 12
[153]
THLE PRIM1
Mean 16.8
Standard deviation 2.1
Values 15 18
[154]
liver PRIM1
Mean 1.84
Standard deviation 0.34
Values 2.1 1.6 2.1 1.5
[155]
ref_hepatocyte PRIM2
Mean 2.32
Standard deviation 2.3
Values 6.1 2.9 0.46 1.4 0.78
[156]
HepG2 PRIM2
Mean 12.4
Standard deviation 3.6
Values 9.9 15
[157]
HepG2.C3A PRIM2
Mean 9.66
Standard deviation 4.4
Values 6.5 13
[158]
HuH.7 PRIM2
Mean 7.1
Standard deviation 1.5
Values 7.8 5.4 8.1
[159]
SNU475 PRIM2
Mean 9.65
Standard deviation 1.6
Values 8.5 11
[160]
THLE PRIM2
Mean 12.8
Standard deviation 1.5
Values 12 14
[161]
liver PRIM2
Mean 1.1
Standard deviation 0.41
Values 0.68 1.5 0.82 1.4
[162]
ref_hepatocyte DBF4
Mean 1.77
Standard deviation 1.2
Values 2.9 2.2 2.6 0.47 0.58
[163]
HepG2 DBF4
Mean 5.5
Standard deviation 2.8
Values 3.5 7.5
[164]
HepG2.C3A DBF4
Mean 15.2
Standard deviation 7.5
Values 10 21
[165]
HuH.7 DBF4
Mean 12.2
Standard deviation 2.1
Values 14 9.8 13
[166]
SNU475 DBF4
Mean 9.71
Standard deviation 2.7
Values 7.8 12
[167]
THLE DBF4
Mean 13.1
Standard deviation 0.25
Values 13 13
[168]
liver DBF4
Mean 1.82
Standard deviation 0.62
Values 2.3 1.9 2.1 0.91
[169]
ref_hepatocyte MCM8
Mean 1.68
Standard deviation 1.7
Values 3.8 3.2 0.45 0.49 0.46
[170]
HepG2 MCM8
Mean 16.9
Standard deviation 9.8
Values 10 24
[171]
HepG2.C3A MCM8
Mean 24.7
Standard deviation 16
Values 14 36
[172]
HuH.7 MCM8
Mean 14.5
Standard deviation 7.7
Values 22 6.3 15
[173]
SNU475 MCM8
Mean 18.7
Standard deviation 3.3
Values 16 21
[174]
THLE MCM8
Mean 15.3
Standard deviation 1.1
Values 15 16
[175]
liver MCM8
Mean 1.84
Standard deviation 1.3
Values 0.8 3.4 0.82 2.3
[176]
ref_hepatocyte ORC1
Mean 1.51
Standard deviation 1.9
Values 4.6 1.8 0.38 0.4 0.31
[177]
HepG2 ORC1
Mean 9.76
Standard deviation 4.5
Values 6.6 13
[178]
HepG2.C3A ORC1
Mean 8.91
Standard deviation 3.7
Values 6.3 11
[179]
HuH.7 ORC1
Mean 24.2
Standard deviation 9.6
Values 31 13 29
[180]
SNU475 ORC1
Mean 6.72
Standard deviation 3.5
Values 4.2 9.2
[181]
THLE ORC1
Mean 11.2
Standard deviation 2.9
Values 9.2 13
[182]
liver ORC1
Mean 0.5
Standard deviation 0.15
Values 0.47 0.56 0.67 0.3
[183]
ref_hepatocyte POLE
Mean 1.41
Standard deviation 0.61
Values 1.7 0.95 0.68 1.5 2.2
[184]
HepG2 POLE
Mean 25.6
Standard deviation 5.9
Values 22 30
[185]
HepG2.C3A POLE
Mean 35.2
Standard deviation 15
Values 24 46
[186]
HuH.7 POLE
Mean 35.1
Standard deviation 18
Values 50 15 40
[187]
SNU475 POLE
Mean 17.2
Standard deviation 0.14
Values 17 17
[188]
THLE POLE
Mean 39
Standard deviation 5
Values 35 43
[189]
liver POLE
Mean 15.3
Standard deviation 8.7
Values 11 19 6 25
[190]
ref_hepatocyte POLE2
Mean 1.24
Standard deviation 0.85
Values 1.7 2.2 0.24 1.6 0.46
[191]
HepG2 POLE2
Mean 4.44
Standard deviation 2.1
Values 3 5.9
[192]
HepG2.C3A POLE2
Mean 6.88
Standard deviation 5.4
Values 3.1 11
[193]
HuH.7 POLE2
Mean 13.1
Standard deviation 7.8
Values 15 4.4 20
[194]
SNU475 POLE2
Mean 5.05
Standard deviation 2
Values 3.6 6.4
[195]
THLE POLE2
Mean 8.23
Standard deviation 0.9
Values 7.6 8.9
[196]
liver POLE2
Mean 0.788
Standard deviation 0.23
Values 0.68 1 0.9 0.53
[197]
ref_hepatocyte CDT1
Mean 1.19
Standard deviation 0.81
Values 2.4 1.5 1 0.6 0.4
[198]
HepG2 CDT1
Mean 24.7
Standard deviation 3.7
Values 27 22
[199]
HepG2.C3A CDT1
Mean 26.9
Standard deviation 5.5
Values 31 23
[200]
HuH.7 CDT1
Mean 71.9
Standard deviation 28
Values 1e+02 44 71
[201]
SNU475 CDT1
Mean 12.6
Standard deviation 4.7
Values 9.3 16
[202]
THLE CDT1
Mean 21.4
Standard deviation 1.4
Values 20 22
[203]
liver CDT1
Mean 0.474
Standard deviation 0.23
Values 0.14 0.59 0.67 0.5
[204]
ref_hepatocyte CDC7
Mean 1.01
Standard deviation 0.88
Values 2 1.9 0.23 0.75 0.18
[205]
HepG2 CDC7
Mean 3.13
Standard deviation 1.9
Values 1.8 4.5
[206]
HepG2.C3A CDC7
Mean 5.45
Standard deviation 3.7
Values 2.9 8
[207]
HuH.7 CDC7
Mean 9.19
Standard deviation 4.7
Values 12 3.7 12
[208]
SNU475 CDC7
Mean 9.87
Standard deviation 2.9
Values 7.8 12
[209]
THLE CDC7
Mean 18.3
Standard deviation 1.1
Values 17 19
[210]
liver CDC7
Mean 0.829
Standard deviation 0.33
Values 0.59 0.91 1.3 0.56
[211]
ref_hepatocyte POLA1
Mean 0.985
Standard deviation 0.81
Values 1.8 2 0.27 0.52 0.41
[212]
HepG2 POLA1
Mean 8.75
Standard deviation 4.7
Values 5.4 12
[213]
HepG2.C3A POLA1
Mean 8.42
Standard deviation 3.5
Values 5.9 11
[214]
HuH.7 POLA1
Mean 11.9
Standard deviation 5.3
Values 17 6.3 13
[215]
SNU475 POLA1
Mean 14.3
Standard deviation 5.6
Values 10 18
[216]
THLE POLA1
Mean 15.7
Standard deviation 1.1
Values 15 17
[217]
liver POLA1
Mean 4.45
Standard deviation 2.4
Values 1.9 7.6 3.5 4.8
[218]
ref_hepatocyte MCM10
Mean 0.862
Standard deviation 0.93
Values 2.2 1.4 0.39 0.13 0.15
[219]
HepG2 MCM10
Mean 10.9
Standard deviation 4.5
Values 7.7 14
[220]
HepG2.C3A MCM10
Mean 15
Standard deviation 13
Values 6 24
[221]
HuH.7 MCM10
Mean 11.4
Standard deviation 7.2
Values 16 3 15
[222]
SNU475 MCM10
Mean 20.4
Standard deviation 9.4
Values 14 27
[223]
THLE MCM10
Mean 16.5
Standard deviation 3.6
Values 14 19
[224]
liver MCM10
Mean 0.396
Standard deviation 0.26
Values 0.26 0.66 0.57 0.11
[225]
ref_hepatocyte RPA4
Mean 0.168
Standard deviation 0.15
Values 0 0.15 0.41 0.18 0.098
[226]
HepG2 RPA4
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[227]
HepG2.C3A RPA4
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[228]
HuH.7 RPA4
Mean 0
Standard deviation 0
Values 0 0 0
[229]
SNU475 RPA4
Mean 0.0927
Standard deviation 0.098
Values 0.023 0.16
[230]
THLE RPA4
Mean 0.103
Standard deviation 0.0041
Values 0.1 0.11
[231]
liver RPA4
Mean 0.857
Standard deviation 0.15
Values 0.94 1 0.67 0.81