REACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [1] 0.07[2] 0.03[3] 0.05[4] 0.09[5] 0.09[6] -0.31[7]
2 CNGA1 cGMP-gated cation channel alpha-1 [8] -9.15[9] -5.16[10] -2.88[11] -8.95[12] -7.58[13] 1.84[14]
3 SLC24A1 Sodium/potassium/calcium exchanger 1 [15] -0.38[16] 0.58[17] 0.39[18] -1.32[19] -1.19[20] 1.18[21]
4 PDE6B Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [22] -1.90[23] -2.36[24] -2.79[25] 0.25[26] -2.73[27] 1.64[28]
5 PDE6A Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [29] -0.88[30] -0.26[31] 0.29[32] 0.27[33] 0.72[34] 2.40[35]
6 GNAT1 Guanine nucleotide-binding protein G(t) subunit alpha-1 [36] -3.73[37] -0.45[38] -0.35[39] -3.44[40] [41] 2.43[42]
7 CNGB1 Cyclic nucleotide-gated cation channel beta-1 [43] 2.36[44] 1.05[45] -0.87[46] -0.74[47] 0.08[48] -1.30[49]
8 PDE6G Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma 3.85[50] 4.94[51] 0.37[52] 1.79[53] 0.31[54] 4.00[55]
9 SAG S-arrestin [56] [57] [58] [59] [60] [61] [62]
10 RHO Rhodopsin [63] [64] [65] [66] [67] [68] [69]
11 GNGT1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 [70] [71] [72] [73] [74] [75] [76]
[1]
ref_hepatocyte GNB1
Mean 42.7
Standard deviation 15
Values 44 60 53 31 24
[2]
HepG2 GNB1
Mean 190
Standard deviation 15
Values 2e+02 1.8e+02
[3]
HepG2.C3A GNB1
Mean 171
Standard deviation 4.5
Values 1.7e+02 1.7e+02
[4]
HuH.7 GNB1
Mean 118
Standard deviation 23
Values 1.4e+02 93 1.2e+02
[5]
SNU475 GNB1
Mean 191
Standard deviation 19
Values 2e+02 1.8e+02
[6]
THLE GNB1
Mean 185
Standard deviation 12
Values 1.8e+02 1.9e+02
[7]
liver GNB1
Mean 25.7
Standard deviation 5
Values 31 25 19 27
[8]
ref_hepatocyte CNGA1
Mean 2.02
Standard deviation 3.1
Values 0 0.39 0.25 2.1 7.3
[9]
HepG2 CNGA1
Mean 0.015
Standard deviation 0.0031
Values 0.017 0.013
[10]
HepG2.C3A CNGA1
Mean 0.222
Standard deviation 0.22
Values 0.38 0.064
[11]
HuH.7 CNGA1
Mean 0.731
Standard deviation 0.39
Values 0.52 1.2 0.49
[12]
SNU475 CNGA1
Mean 0.0171
Standard deviation 0.0045
Values 0.014 0.02
[13]
THLE CNGA1
Mean 0.0429
Standard deviation 0.023
Values 0.059 0.027
[14]
liver CNGA1
Mean 5.43
Standard deviation 6.2
Values 15 2.4 2.4 2.2
[15]
ref_hepatocyte SLC24A1
Mean 1.34
Standard deviation 0.76
Values 1.7 2.5 0.93 0.63 0.95
[16]
HepG2 SLC24A1
Mean 4.39
Standard deviation 0.19
Values 4.3 4.5
[17]
HepG2.C3A SLC24A1
Mean 7.91
Standard deviation 0.14
Values 7.8 8
[18]
HuH.7 SLC24A1
Mean 4.71
Standard deviation 0.68
Values 5.5 4.4 4.3
[19]
SNU475 SLC24A1
Mean 2.26
Standard deviation 0.49
Values 2.6 1.9
[20]
THLE SLC24A1
Mean 2.4
Standard deviation 0.33
Values 2.2 2.6
[21]
liver SLC24A1
Mean 2.29
Standard deviation 1.3
Values 1.2 2.7 1.3 4
[22]
ref_hepatocyte PDE6B
Mean 0.153
Standard deviation 0.21
Values 0 0.51 0 0.13 0.13
[23]
HepG2 PDE6B
Mean 0.173
Standard deviation 0.16
Values 0.29 0.06
[24]
HepG2.C3A PDE6B
Mean 0.117
Standard deviation 0.014
Values 0.13 0.11
[25]
HuH.7 PDE6B
Mean 0.0593
Standard deviation 0.031
Values 0.033 0.051 0.094
[26]
SNU475 PDE6B
Mean 0.763
Standard deviation 0.22
Values 0.92 0.61
[27]
THLE PDE6B
Mean 0.0937
Standard deviation 0.035
Values 0.12 0.069
[28]
liver PDE6B
Mean 0.359
Standard deviation 0.17
Values 0.19 0.27 0.57 0.41
[29]
ref_hepatocyte PDE6A
Mean 0.142
Standard deviation 0.1
Values 0.18 0.25 0 0.069 0.2
[30]
HepG2 PDE6A
Mean 0.327
Standard deviation 0.11
Values 0.25 0.41
[31]
HepG2.C3A PDE6A
Mean 0.468
Standard deviation 0.04
Values 0.5 0.44
[32]
HuH.7 PDE6A
Mean 0.463
Standard deviation 0.1
Values 0.34 0.5 0.54
[33]
SNU475 PDE6A
Mean 0.718
Standard deviation 0.49
Values 1.1 0.37
[34]
THLE PDE6A
Mean 0.955
Standard deviation 0.087
Values 0.89 1
[35]
liver PDE6A
Mean 0.564
Standard deviation 0.23
Values 0.4 0.71 0.33 0.81
[36]
ref_hepatocyte GNAT1
Mean 0.0626
Standard deviation 0.095
Values 0 0 0 0.22 0.098
[37]
HepG2 GNAT1
Mean 0.0201
Standard deviation 0.028
Values 0.04 0
[38]
HepG2.C3A GNAT1
Mean 0.18
Standard deviation 0.088
Values 0.24 0.12
[39]
HuH.7 GNAT1
Mean 0.132
Standard deviation 0.12
Values 0.016 0.26 0.12
[40]
SNU475 GNAT1
Mean 0.0243
Standard deviation 0.0015
Values 0.023 0.025
[41]
THLE GNAT1
Mean 0
Standard deviation 0
Values 0 0
[42]
liver GNAT1
Mean 0.254
Standard deviation 0.26
Values 0.071 0.44 0 0.5
[43]
ref_hepatocyte CNGB1
Mean 0.0342
Standard deviation 0.072
Values 0 0 0.16 0 0.0081
[44]
HepG2 CNGB1
Mean 0.748
Standard deviation 0.58
Values 1.2 0.34
[45]
HepG2.C3A CNGB1
Mean 0.28
Standard deviation 0.17
Values 0.4 0.16
[46]
HuH.7 CNGB1
Mean 0.0499
Standard deviation 0.016
Values 0.033 0.051 0.066
[47]
SNU475 CNGB1
Mean 0.0859
Standard deviation 0.036
Values 0.06 0.11
[48]
THLE CNGB1
Mean 0.147
Standard deviation 0.035
Values 0.17 0.12
[49]
liver CNGB1
Mean 0.0104
Standard deviation 0.014
Values 0 0.029 0 0.013
[50]
ref_hepatocyte PDE6G
Mean 0.0163
Standard deviation 0.036
Values 0 0 0 0 0.081
[51]
HepG2 PDE6G
Mean 0.997
Standard deviation 0.04
Values 0.97 1
[52]
HepG2.C3A PDE6G
Mean 1.96
Standard deviation 0.59
Values 2.4 1.5
[53]
HuH.7 PDE6G
Mean 0.0562
Standard deviation 0.018
Values 0.074 0.039 0.056
[54]
SNU475 PDE6G
Mean 0.236
Standard deviation 0.047
Values 0.27 0.2
[55]
THLE PDE6G
Mean 0.0822
Standard deviation 0.026
Values 0.1 0.064
[56]
liver PDE6G
Mean 0.195
Standard deviation 0.22
Values 0.49 0.029 0.23 0.026
[57]
ref_hepatocyte SAG
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 SAG
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A SAG
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[60]
HuH.7 SAG
Mean 0.0207
Standard deviation 0.019
Values 0.025 0 0.037
[61]
SNU475 SAG
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[62]
THLE SAG
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[63]
liver SAG
Mean 0
Standard deviation 0
Values 0 0 0 0
[64]
ref_hepatocyte RHO
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 RHO
Mean 0.122
Standard deviation 0.1
Values 0.052 0.19
[66]
HepG2.C3A RHO
Mean 0.141
Standard deviation 0.089
Values 0.078 0.2
[67]
HuH.7 RHO
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[68]
SNU475 RHO
Mean 0.0377
Standard deviation 0.032
Values 0.06 0.015
[69]
THLE RHO
Mean 0
Standard deviation 0
Values 0 0
[70]
liver RHO
Mean 0
Standard deviation 0
Values 0 0 0 0
[71]
ref_hepatocyte GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 GNGT1
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A GNGT1
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 GNGT1
Mean 0.0409
Standard deviation 0.035
Values 0.0082 0.077 0.037
[75]
SNU475 GNGT1
Mean 0.0679
Standard deviation 0.0043
Values 0.065 0.071
[76]
THLE GNGT1
Mean 0
Standard deviation 0
Values 0 0
[77]
liver GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0