REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 JUN Transcription factor AP-1 [1] -0.54[2] -2.14[3] -1.78[4] -1.62[5] -0.84[6] -1.69[7]
2 FOS Proto-oncogene c-Fos [8] -6.07[9] -4.86[10] -5.43[11] -6.09[12] -4.81[13] -1.19[14]
3 MAPK1 Mitogen-activated protein kinase 1 [15] 1.66[16] 1.74[17] 1.66[18] 1.93[19] 1.79[20] 1.89[21]
4 MAPK14 Mitogen-activated protein kinase 14 [22] 1.42[23] 1.44[24] 1.10[25] 1.76[26] 1.45[27] 1.40[28]
5 ATF2 Cyclic AMP-dependent transcription factor ATF-2 [29] 0.59[30] 1.58[31] 1.90[32] 0.86[33] 0.85[34] 1.14[35]
6 MAPK8 Mitogen-activated protein kinase 8 [36] -1.50[37] -0.14[38] -1.18[39] -0.82[40] -0.75[41] -0.39[42]
7 MAPK9 Mitogen-activated protein kinase 9 [43] 1.17[44] 1.35[45] 1.50[46] 1.79[47] 1.46[48] 0.63[49]
8 MAPK3 Mitogen-activated protein kinase 3 [50] 1.80[51] 1.79[52] 1.92[53] 0.50[54] 0.74[55] -0.92[56]
9 MAPK11 Mitogen-activated protein kinase 11 [57] -0.22[58] -0.38[59] -1.18[60] 0.43[61] 2.64[62] 0.28[63]
10 MAPK10 Mitogen-activated protein kinase 10 [64] -1.54[65] [66] [67] 8.99[68] 4.94[69] 7.37[70]
[1]
ref_hepatocyte JUN
Mean 42.9
Standard deviation 25
Values 26 30 66 73 20
[2]
HepG2 JUN
Mean 67.5
Standard deviation 36
Values 93 42
[3]
HepG2.C3A JUN
Mean 20.6
Standard deviation 11
Values 28 13
[4]
HuH.7 JUN
Mean 23.9
Standard deviation 19
Values 11 46 14
[5]
SNU475 JUN
Mean 24.2
Standard deviation 4.1
Values 21 27
[6]
THLE JUN
Mean 40.2
Standard deviation 4.7
Values 37 44
[7]
liver JUN
Mean 17.4
Standard deviation 8.4
Values 25 24 8.4 12
[8]
ref_hepatocyte FOS
Mean 40
Standard deviation 67
Values 4 0.65 9 1.6e+02 27
[9]
HepG2 FOS
Mean 1.37
Standard deviation 1
Values 2.1 0.66
[10]
HepG2.C3A FOS
Mean 2.92
Standard deviation 1.9
Values 4.3 1.6
[11]
HuH.7 FOS
Mean 1.77
Standard deviation 0.38
Values 1.5 1.6 2.2
[12]
SNU475 FOS
Mean 1.02
Standard deviation 0.13
Values 0.93 1.1
[13]
THLE FOS
Mean 2.4
Standard deviation 0.3
Values 2.2 2.6
[14]
liver FOS
Mean 23
Standard deviation 32
Values 71 4.8 10 5.7
[15]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[16]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[17]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[18]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[19]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[20]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[21]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[22]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 12 8.5 7.2 7.5 8.3
[23]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 47 60
[24]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[25]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 37 36 34
[26]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 52 51
[27]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[28]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 24 38 22 37
[29]
ref_hepatocyte ATF2
Mean 7.65
Standard deviation 3.4
Values 12 6.7 9.4 3.3 6.6
[30]
HepG2 ATF2
Mean 26.3
Standard deviation 12
Values 18 35
[31]
HepG2.C3A ATF2
Mean 48.4
Standard deviation 7.6
Values 43 54
[32]
HuH.7 ATF2
Mean 54.5
Standard deviation 4.5
Values 55 59 50
[33]
SNU475 ATF2
Mean 24.2
Standard deviation 8.8
Values 30 18
[34]
THLE ATF2
Mean 23.1
Standard deviation 0.6
Values 24 23
[35]
liver ATF2
Mean 22
Standard deviation 3.2
Values 19 26 23 20
[36]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 6.5 5.6 15 3.8 4.7
[37]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 5.1 6.5
[38]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 11 17
[39]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 6.5 6.2 5.2
[40]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 7.3 6.6
[41]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[42]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.3 7.8 5.6 7.6
[43]
ref_hepatocyte MAPK9
Mean 4.45
Standard deviation 2.7
Values 8.6 5.3 1.4 3.7 3.3
[44]
HepG2 MAPK9
Mean 23
Standard deviation 4.4
Values 20 26
[45]
HepG2.C3A MAPK9
Mean 24
Standard deviation 3.3
Values 22 26
[46]
HuH.7 MAPK9
Mean 24
Standard deviation 2.9
Values 26 21 25
[47]
SNU475 MAPK9
Mean 26.8
Standard deviation 2.4
Values 29 25
[48]
THLE MAPK9
Mean 20.6
Standard deviation 0.2
Values 21 21
[49]
liver MAPK9
Mean 9.01
Standard deviation 3.1
Values 7.1 12 5.7 11
[50]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 3.6 6 3.3
[51]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[52]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[53]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[54]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[55]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[56]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 5 0.81 4.8 0.82
[57]
ref_hepatocyte MAPK11
Mean 0.382
Standard deviation 0.29
Values 0 0.34 0.22 0.71 0.64
[58]
HepG2 MAPK11
Mean 0.749
Standard deviation 0.18
Values 0.62 0.88
[59]
HepG2.C3A MAPK11
Mean 0.621
Standard deviation 0.12
Values 0.53 0.71
[60]
HuH.7 MAPK11
Mean 0.322
Standard deviation 0.15
Values 0.28 0.2 0.49
[61]
SNU475 MAPK11
Mean 0.898
Standard deviation 0.33
Values 1.1 0.66
[62]
THLE MAPK11
Mean 4.01
Standard deviation 0.7
Values 4.5 3.5
[63]
liver MAPK11
Mean 0.609
Standard deviation 0.32
Values 0.96 0.49 0.23 0.75
[64]
ref_hepatocyte MAPK10
Mean 0.00272
Standard deviation 0.0061
Values 0 0 0.014 0 0
[65]
HepG2 MAPK10
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[66]
HepG2.C3A MAPK10
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 MAPK10
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 MAPK10
Mean 2.4
Standard deviation 0.56
Values 2.8 2
[69]
THLE MAPK10
Mean 0.14
Standard deviation 0.07
Values 0.19 0.09
[70]
liver MAPK10
Mean 0.586
Standard deviation 0.14
Values 0.52 0.8 0.54 0.49