REACTOME_ACTIVATION_OF_RAC1 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAC1 Ras-related C3 botulinum toxin substrate 1 [1] -0.73[2] -1.14[3] -0.51[4] -0.31[5] -0.46[6] -0.91[7]
2 NCK1 Cytoplasmic protein NCK1 [8] -1.93[9] -1.91[10] -1.88[11] -0.88[12] -0.91[13] -0.42[14]
3 PAK2 Serine/threonine-protein kinase PAK 2 [15] 1.11[16] 0.77[17] 0.99[18] 0.43[19] 0.84[20] 1.42[21]
4 SOS1 Son of sevenless homolog 1 [22] -0.43[23] 1.01[24] 0.44[25] 0.52[26] -0.38[27] 0.59[28]
5 NCK2 Cytoplasmic protein NCK2 [29] 0.46[30] -0.04[31] -1.70[32] -0.65[33] -0.04[34] -0.77[35]
6 PAK4 Serine/threonine-protein kinase PAK 4 [36] 0.56[37] 0.52[38] 1.13[39] 0.70[40] 0.29[41] -0.28[42]
7 ROBO1 Roundabout homolog 1 [43] 2.43[44] 2.78[45] 1.43[46] 1.18[47] 1.18[48] -0.06[49]
8 SOS2 Son of sevenless homolog 2 [50] -0.36[51] 0.68[52] -0.17[53] 1.37[54] 1.09[55] 1.89[56]
9 PAK1 Serine/threonine-protein kinase PAK 1 [57] -0.34[58] -1.19[59] 1.14[60] -2.18[61] 1.46[62] 0.32[63]
10 SLIT2 Slit homolog 2 protein [64] -1.58[65] -5.60[66] -0.69[67] 1.86[68] 1.19[69] 3.05[70]
11 PAK3 Serine/threonine-protein kinase PAK 3 [71] -6.74[72] [73] [74] -1.92[75] -0.34[76] 0.84[77]
12 PAK6 Serine/threonine-protein kinase PAK 6 [78] -2.01[79] [80] 0.56[81] 1.88[82] 0.85[83] -1.02[84]
13 PAK5 Serine/threonine-protein kinase PAK 5 [85] [86] [87] [88] [89] [90] [91]
[1]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[2]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[3]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[4]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[5]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[6]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[7]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[8]
ref_hepatocyte NCK1
Mean 11
Standard deviation 7.6
Values 4.9 23 13 6.3 7.3
[9]
HepG2 NCK1
Mean 8.05
Standard deviation 1.5
Values 7 9.1
[10]
HepG2.C3A NCK1
Mean 7.7
Standard deviation 1.8
Values 6.4 9
[11]
HuH.7 NCK1
Mean 7.97
Standard deviation 0.27
Values 7.7 7.9 8.2
[12]
SNU475 NCK1
Mean 13.7
Standard deviation 1.9
Values 15 12
[13]
THLE NCK1
Mean 16.6
Standard deviation 0.3
Values 16 17
[14]
liver NCK1
Mean 11.3
Standard deviation 2.9
Values 15 11 12 7.7
[15]
ref_hepatocyte PAK2
Mean 10.9
Standard deviation 2.8
Values 11 15 11 7.6 9.9
[16]
HepG2 PAK2
Mean 65.6
Standard deviation 14
Values 56 75
[17]
HepG2.C3A PAK2
Mean 49.1
Standard deviation 0.79
Values 49 50
[18]
HuH.7 PAK2
Mean 57.7
Standard deviation 11
Values 66 61 46
[19]
SNU475 PAK2
Mean 33.8
Standard deviation 4.3
Values 37 31
[20]
THLE PAK2
Mean 55.3
Standard deviation 9.9
Values 48 62
[21]
liver PAK2
Mean 39.9
Standard deviation 5.7
Values 44 41 43 32
[22]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[23]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[24]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[25]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[26]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[27]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[28]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[29]
ref_hepatocyte NCK2
Mean 4.8
Standard deviation 3.5
Values 9.1 5.5 7 1.3 1
[30]
HepG2 NCK2
Mean 18.4
Standard deviation 3.6
Values 21 16
[31]
HepG2.C3A NCK2
Mean 12.3
Standard deviation 3.8
Values 15 9.6
[32]
HuH.7 NCK2
Mean 3.94
Standard deviation 0.32
Values 3.8 4.3 3.7
[33]
SNU475 NCK2
Mean 7.02
Standard deviation 0.0081
Values 7 7
[34]
THLE NCK2
Mean 13.2
Standard deviation 0.15
Values 13 13
[35]
liver NCK2
Mean 3.85
Standard deviation 2.3
Values 3.3 3.9 1.3 6.9
[36]
ref_hepatocyte PAK4
Mean 4.7
Standard deviation 2.1
Values 3 2.6 7.2 6.8 3.9
[37]
HepG2 PAK4
Mean 19.3
Standard deviation 1
Values 20 19
[38]
HepG2.C3A PAK4
Mean 17.7
Standard deviation 1.5
Values 19 17
[39]
HuH.7 PAK4
Mean 27.4
Standard deviation 6.7
Values 32 20 30
[40]
SNU475 PAK4
Mean 17.5
Standard deviation 6.4
Values 22 13
[41]
THLE PAK4
Mean 16.2
Standard deviation 2.8
Values 14 18
[42]
liver PAK4
Mean 5.31
Standard deviation 2.4
Values 7.3 3 7.5 3.5
[43]
ref_hepatocyte ROBO1
Mean 3.39
Standard deviation 7.3
Values 16 0.016 0.41 0.043 0.13
[44]
HepG2 ROBO1
Mean 51
Standard deviation 6.3
Values 47 55
[45]
HepG2.C3A ROBO1
Mean 61.4
Standard deviation 6.1
Values 66 57
[46]
HuH.7 ROBO1
Mean 24.4
Standard deviation 5.9
Values 26 29 18
[47]
SNU475 ROBO1
Mean 17.7
Standard deviation 2.6
Values 20 16
[48]
THLE ROBO1
Mean 21.8
Standard deviation 6
Values 18 26
[49]
liver ROBO1
Mean 4.47
Standard deviation 1.3
Values 3.4 5.7 3.3 5.6
[50]
ref_hepatocyte SOS2
Mean 2.58
Standard deviation 0.97
Values 4 2.6 2.8 1.5 1.9
[51]
HepG2 SOS2
Mean 5.6
Standard deviation 3
Values 3.5 7.7
[52]
HepG2.C3A SOS2
Mean 10.9
Standard deviation 0.059
Values 11 11
[53]
HuH.7 SOS2
Mean 6.11
Standard deviation 1.7
Values 6.5 7.5 4.3
[54]
SNU475 SOS2
Mean 15.3
Standard deviation 6
Values 19 11
[55]
THLE SOS2
Mean 15.6
Standard deviation 2.6
Values 17 14
[56]
liver SOS2
Mean 13.1
Standard deviation 7.3
Values 7.4 19 6.2 20
[57]
ref_hepatocyte PAK1
Mean 2.3
Standard deviation 0.59
Values 1.7 3 2.9 2.1 1.9
[58]
HepG2 PAK1
Mean 5.05
Standard deviation 1.5
Values 6.1 4
[59]
HepG2.C3A PAK1
Mean 2.65
Standard deviation 0.51
Values 3 2.3
[60]
HuH.7 PAK1
Mean 13.5
Standard deviation 2.2
Values 12 16 12
[61]
SNU475 PAK1
Mean 1.17
Standard deviation 0.24
Values 1 1.3
[62]
THLE PAK1
Mean 18
Standard deviation 0.72
Values 18 17
[63]
liver PAK1
Mean 3.94
Standard deviation 1.1
Values 5.3 4 3.9 2.6
[64]
ref_hepatocyte SLIT2
Mean 0.099
Standard deviation 0.14
Values 0 0.21 0.28 0 0
[65]
HepG2 SLIT2
Mean 0.0923
Standard deviation 0.04
Values 0.12 0.064
[66]
HepG2.C3A SLIT2
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[67]
HuH.7 SLIT2
Mean 0.164
Standard deviation 0.11
Values 0.082 0.29 0.12
[68]
SNU475 SLIT2
Mean 0.824
Standard deviation 0.57
Values 0.42 1.2
[69]
THLE SLIT2
Mean 0.639
Standard deviation 0.075
Values 0.59 0.69
[70]
liver SLIT2
Mean 1.12
Standard deviation 0.57
Values 0.63 1.2 0.74 1.9
[71]
ref_hepatocyte PAK3
Mean 0.0826
Standard deviation 0.14
Values 0 0 0.33 0 0.081
[72]
HepG2 PAK3
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[73]
HepG2.C3A PAK3
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 PAK3
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 PAK3
Mean 0.05
Standard deviation 0.051
Values 0.014 0.086
[76]
THLE PAK3
Mean 0.185
Standard deviation 0.065
Values 0.23 0.14
[77]
liver PAK3
Mean 0.202
Standard deviation 0.041
Values 0.24 0.14 0.21 0.23
[78]
ref_hepatocyte PAK6
Mean 0.0735
Standard deviation 0.06
Values 0.11 0.028 0.16 0.043 0.024
[79]
HepG2 PAK6
Mean 0.0508
Standard deviation 0.007
Values 0.046 0.056
[80]
HepG2.C3A PAK6
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 PAK6
Mean 0.288
Standard deviation 0.11
Values 0.41 0.26 0.2
[82]
SNU475 PAK6
Mean 0.621
Standard deviation 0.047
Values 0.65 0.59
[83]
THLE PAK6
Mean 0.376
Standard deviation 0.012
Values 0.38 0.37
[84]
liver PAK6
Mean 0.0496
Standard deviation 0.045
Values 0.12 0.029 0.026 0.026
[85]
ref_hepatocyte PAK5
Missing
[86]
HepG2 PAK5
Missing
[87]
HepG2.C3A PAK5
Missing
[88]
HuH.7 PAK5
Missing
[89]
SNU475 PAK5
Missing
[90]
THLE PAK5
Missing
[91]
liver PAK5
Missing