REACTOME_ACTIVATION_OF_CASPASES_THROUGH_APOPTOSOME_MEDIATED_CLEAVAGE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYCS Cytochrome c [1] 0.59[2] 0.44[3] 0.70[4] 0.53[5] 0.78[6] 0.58[7]
2 CASP3 Caspase-3 [8] -0.61[9] -0.28[10] -2.64[11] -1.69[12] -0.86[13] -1.54[14]
3 CASP7 Caspase-7 [15] -1.05[16] -1.76[17] -1.14[18] -1.69[19] -1.65[20] -1.22[21]
4 XIAP E3 ubiquitin-protein ligase XIAP [22] 0.78[23] 1.02[24] 1.66[25] 1.80[26] 1.06[27] 1.94[28]
5 CASP9 Caspase-9 [29] -0.59[30] 0.03[31] -0.67[32] -0.55[33] -1.40[34] -1.28[35]
6 APAF1 Apoptotic protease-activating factor 1 [36] 0.92[37] 1.00[38] 1.43[39] 1.83[40] 0.77[41] 0.75[42]
[1]
ref_hepatocyte CYCS
Mean 14.3
Standard deviation 4.3
Values 16 19 7.5 15 14
[2]
HepG2 CYCS
Mean 79.8
Standard deviation 18
Values 67 93
[3]
HepG2.C3A CYCS
Mean 81.4
Standard deviation 39
Values 54 1.1e+02
[4]
HuH.7 CYCS
Mean 82.3
Standard deviation 19
Values 93 60 94
[5]
SNU475 CYCS
Mean 66.3
Standard deviation 0.99
Values 66 67
[6]
THLE CYCS
Mean 98.4
Standard deviation 7.6
Values 93 1e+02
[7]
liver CYCS
Mean 50.8
Standard deviation 34
Values 59 30 95 19
[8]
ref_hepatocyte CASP3
Mean 12.5
Standard deviation 12
Values 33 13 6.8 4.9 5.1
[9]
HepG2 CASP3
Mean 30.3
Standard deviation 8.2
Values 25 36
[10]
HepG2.C3A CASP3
Mean 43.1
Standard deviation 22
Values 27 59
[11]
HuH.7 CASP3
Mean 7.08
Standard deviation 1
Values 5.9 7.5 7.8
[12]
SNU475 CASP3
Mean 12.3
Standard deviation 0.36
Values 13 12
[13]
THLE CASP3
Mean 27.6
Standard deviation 0.68
Values 27 28
[14]
liver CASP3
Mean 10.2
Standard deviation 4.2
Values 9.5 9 16 6.1
[15]
ref_hepatocyte CASP7
Mean 10
Standard deviation 4.1
Values 7.8 14 15 7.6 6
[16]
HepG2 CASP7
Mean 17.9
Standard deviation 4
Values 15 21
[17]
HepG2.C3A CASP7
Mean 12.4
Standard deviation 4
Values 9.5 15
[18]
HuH.7 CASP7
Mean 16.1
Standard deviation 1.8
Values 15 15 18
[19]
SNU475 CASP7
Mean 9.89
Standard deviation 0.26
Values 10 9.7
[20]
THLE CASP7
Mean 12.8
Standard deviation 0.29
Values 13 13
[21]
liver CASP7
Mean 10.2
Standard deviation 3.1
Values 14 6.6 9.7 10
[22]
ref_hepatocyte XIAP
Mean 2.63
Standard deviation 0.63
Values 2.6 3.3 2.1 1.9 3.2
[23]
HepG2 XIAP
Mean 16.7
Standard deviation 3.8
Values 14 19
[24]
HepG2.C3A XIAP
Mean 22.3
Standard deviation 5.6
Values 18 26
[25]
HuH.7 XIAP
Mean 29.4
Standard deviation 6.2
Values 34 31 22
[26]
SNU475 XIAP
Mean 29.2
Standard deviation 5.9
Values 33 25
[27]
THLE XIAP
Mean 21.9
Standard deviation 3.4
Values 19 24
[28]
liver XIAP
Mean 24
Standard deviation 7.9
Values 19 34 16 27
[29]
ref_hepatocyte CASP9
Mean 2.59
Standard deviation 1
Values 1.9 1.9 2 2.7 4.4
[30]
HepG2 CASP9
Mean 6.38
Standard deviation 0.81
Values 5.8 7
[31]
HepG2.C3A CASP9
Mean 11.1
Standard deviation 0.21
Values 11 11
[32]
HuH.7 CASP9
Mean 5.76
Standard deviation 1.5
Values 6.7 4.1 6.6
[33]
SNU475 CASP9
Mean 5.65
Standard deviation 0.92
Values 6.3 5
[34]
THLE CASP9
Mean 3.94
Standard deviation 0.43
Values 3.6 4.2
[35]
liver CASP9
Mean 2.54
Standard deviation 1.2
Values 2.4 1.9 4.2 1.6
[36]
ref_hepatocyte APAF1
Mean 1.36
Standard deviation 0.48
Values 1.9 1.8 1.2 0.79 1.1
[37]
HepG2 APAF1
Mean 9.46
Standard deviation 4.9
Values 6 13
[38]
HepG2.C3A APAF1
Mean 11.3
Standard deviation 2.5
Values 9.5 13
[39]
HuH.7 APAF1
Mean 12.9
Standard deviation 2.1
Values 15 12 12
[40]
SNU475 APAF1
Mean 15.4
Standard deviation 1.9
Values 17 14
[41]
THLE APAF1
Mean 9.25
Standard deviation 1.4
Values 8.2 10
[42]
liver APAF1
Mean 5.4
Standard deviation 3.4
Values 2.4 8.5 2.5 8.2