REACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 YWHAE 14-3-3 protein epsilon [1] -0.81[2] -0.55[3] -0.17[4] -1.17[5] -0.47[6] -0.39[7]
2 YWHAZ 14-3-3 protein zeta/delta [8] -0.14[9] -0.14[10] 0.21[11] 0.59[12] -0.16[13] -0.48[14]
3 YWHAH 14-3-3 protein eta [15] -0.94[16] -1.20[17] -1.19[18] -1.50[19] -1.24[20] -0.80[21]
4 YWHAQ 14-3-3 protein theta [22] 0.69[23] 0.66[24] 0.40[25] 1.05[26] 1.03[27] 0.56[28]
5 SFN 14-3-3 protein sigma [29] -1.93[30] -2.14[31] -1.71[32] -8.14[33] -8.41[34] -8.93[35]
6 YWHAG 14-3-3 protein gamma [36] 0.63[37] 0.25[38] 0.34[39] 0.41[40] 0.38[41] -0.18[42]
7 YWHAB 14-3-3 protein beta/alpha [43] 1.47[44] 1.33[45] 0.64[46] 0.99[47] 1.09[48] 1.06[49]
8 AKT1 RAC-alpha serine/threonine-protein kinase [50] 0.51[51] 0.43[52] -0.62[53] -0.36[54] 0.32[55] 0.92[56]
9 BAD Bcl2-associated agonist of cell death [57] -1.24[58] -0.96[59] -1.88[60] -1.38[61] -0.31[62] -0.26[63]
10 PPP3R1 Calcineurin subunit B type 1 [64] 0.62[65] 0.95[66] 0.89[67] 0.39[68] 0.82[69] 0.01[70]
11 BID BH3-interacting domain death agonist [71] 0.16[72] 0.42[73] 0.07[74] -0.60[75] -0.47[76] 1.34[77]
12 AKT2 RAC-beta serine/threonine-protein kinase [78] 1.39[79] 1.82[80] 1.98[81] 0.55[82] 1.00[83] 2.29[84]
13 PPP3CC Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform -0.27[85] 0.02[86] -0.35[87] -1.40[88] 0.18[89] 1.22[90]
14 AKT3 RAC-gamma serine/threonine-protein kinase [91] -1.41[92] -3.82[93] -3.10[94] 5.53[95] 5.15[96] 4.77[97]
15 BCL2 Apoptosis regulator Bcl-2 [98] -2.42[99] 3.13[100] -4.24[101] 1.46[102] 1.84[103] 4.39[104]
[1]
ref_hepatocyte YWHAE
Mean 195
Standard deviation 97
Values 2.2e+02 3.6e+02 1.6e+02 1.3e+02 1.2e+02
[2]
HepG2 YWHAE
Mean 183
Standard deviation 1.8
Values 1.8e+02 1.8e+02
[3]
HepG2.C3A YWHAE
Mean 175
Standard deviation 29
Values 1.5e+02 2e+02
[4]
HuH.7 YWHAE
Mean 215
Standard deviation 62
Values 2.1e+02 1.5e+02 2.8e+02
[5]
SNU475 YWHAE
Mean 197
Standard deviation 19
Values 2.1e+02 1.8e+02
[6]
THLE YWHAE
Mean 227
Standard deviation 21
Values 2.1e+02 2.4e+02
[7]
liver YWHAE
Mean 94.2
Standard deviation 60
Values 1.3e+02 52 1.6e+02 36
[8]
ref_hepatocyte YWHAZ
Mean 161
Standard deviation 1.6e+02
Values 1.3e+02 4.3e+02 1.6e+02 40 41
[9]
HepG2 YWHAZ
Mean 239
Standard deviation 21
Values 2.2e+02 2.5e+02
[10]
HepG2.C3A YWHAZ
Mean 191
Standard deviation 28
Values 1.7e+02 2.1e+02
[11]
HuH.7 YWHAZ
Mean 229
Standard deviation 23
Values 2.5e+02 2.1e+02 2.3e+02
[12]
SNU475 YWHAZ
Mean 552
Standard deviation 94
Values 6.2e+02 4.9e+02
[13]
THLE YWHAZ
Mean 232
Standard deviation 39
Values 2e+02 2.6e+02
[14]
liver YWHAZ
Mean 73.1
Standard deviation 31
Values 81 60 1.1e+02 39
[15]
ref_hepatocyte YWHAH
Mean 64.6
Standard deviation 51
Values 41 1.3e+02 1e+02 26 19
[16]
HepG2 YWHAH
Mean 55.3
Standard deviation 3.4
Values 58 53
[17]
HepG2.C3A YWHAH
Mean 37
Standard deviation 4.4
Values 34 40
[18]
HuH.7 YWHAH
Mean 34.8
Standard deviation 9.2
Values 36 25 43
[19]
SNU475 YWHAH
Mean 51.9
Standard deviation 3.7
Values 55 49
[20]
THLE YWHAH
Mean 44
Standard deviation 12
Values 36 52
[21]
liver YWHAH
Mean 23.6
Standard deviation 16
Values 39 11 36 8.3
[22]
ref_hepatocyte YWHAQ
Mean 63.6
Standard deviation 28
Values 49 1e+02 86 44 39
[23]
HepG2 YWHAQ
Mean 169
Standard deviation 33
Values 1.5e+02 1.9e+02
[24]
HepG2.C3A YWHAQ
Mean 132
Standard deviation 50
Values 96 1.7e+02
[25]
HuH.7 YWHAQ
Mean 103
Standard deviation 30
Values 1.2e+02 69 1.2e+02
[26]
SNU475 YWHAQ
Mean 299
Standard deviation 36
Values 3.2e+02 2.7e+02
[27]
THLE YWHAQ
Mean 210
Standard deviation 34
Values 1.9e+02 2.3e+02
[28]
liver YWHAQ
Mean 59.7
Standard deviation 29
Values 70 42 95 31
[29]
ref_hepatocyte SFN
Mean 59.2
Standard deviation 90
Values 6.3 2.1e+02 78 1.8 0.87
[30]
HepG2 SFN
Mean 25.4
Standard deviation 7.7
Values 31 20
[31]
HepG2.C3A SFN
Mean 17.7
Standard deviation 2.5
Values 16 19
[32]
HuH.7 SFN
Mean 22.3
Standard deviation 9.2
Values 25 12 30
[33]
SNU475 SFN
Mean 0.477
Standard deviation 0.46
Values 0.15 0.81
[34]
THLE SFN
Mean 0.281
Standard deviation 0.029
Values 0.3 0.26
[35]
liver SFN
Mean 0.0769
Standard deviation 0.053
Values 0 0.086 0.1 0.12
[36]
ref_hepatocyte YWHAG
Mean 50.4
Standard deviation 40
Values 70 1.1e+02 35 18 18
[37]
HepG2 YWHAG
Mean 128
Standard deviation 6.2
Values 1.3e+02 1.2e+02
[38]
HepG2.C3A YWHAG
Mean 78.7
Standard deviation 6.4
Values 74 83
[39]
HuH.7 YWHAG
Mean 78.6
Standard deviation 11
Values 91 70 74
[40]
SNU475 YWHAG
Mean 152
Standard deviation 34
Values 1.8e+02 1.3e+02
[41]
THLE YWHAG
Mean 106
Standard deviation 7.5
Values 1e+02 1.1e+02
[42]
liver YWHAG
Mean 28.2
Standard deviation 12
Values 21 40 15 37
[43]
ref_hepatocyte YWHAB
Mean 42.6
Standard deviation 20
Values 74 47 41 28 22
[44]
HepG2 YWHAB
Mean 193
Standard deviation 37
Values 1.7e+02 2.2e+02
[45]
HepG2.C3A YWHAB
Mean 141
Standard deviation 27
Values 1.2e+02 1.6e+02
[46]
HuH.7 YWHAB
Mean 82.2
Standard deviation 26
Values 98 52 97
[47]
SNU475 YWHAB
Mean 193
Standard deviation 7
Values 2e+02 1.9e+02
[48]
THLE YWHAB
Mean 146
Standard deviation 23
Values 1.3e+02 1.6e+02
[49]
liver YWHAB
Mean 56.6
Standard deviation 26
Values 78 39 80 30
[50]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[51]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[52]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[53]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[54]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[55]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[56]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[57]
ref_hepatocyte BAD
Mean 16.7
Standard deviation 11
Values 5.4 16 6.7 28 27
[58]
HepG2 BAD
Mean 11.6
Standard deviation 0.78
Values 11 12
[59]
HepG2.C3A BAD
Mean 11.3
Standard deviation 1.1
Values 10 12
[60]
HuH.7 BAD
Mean 5.61
Standard deviation 0.7
Values 5 6.4 5.5
[61]
SNU475 BAD
Mean 14.6
Standard deviation 2.5
Values 16 13
[62]
THLE BAD
Mean 21.6
Standard deviation 1.3
Values 21 23
[63]
liver BAD
Mean 8.85
Standard deviation 6.2
Values 16 3.7 12 3.7
[64]
ref_hepatocyte PPP3R1
Mean 13
Standard deviation 4.5
Values 19 16 9.2 8.1 13
[65]
HepG2 PPP3R1
Mean 32.8
Standard deviation 2.3
Values 31 34
[66]
HepG2.C3A PPP3R1
Mean 33.2
Standard deviation 2.2
Values 32 35
[67]
HuH.7 PPP3R1
Mean 29.9
Standard deviation 3.7
Values 34 29 27
[68]
SNU475 PPP3R1
Mean 39.1
Standard deviation 2.2
Values 38 41
[69]
THLE PPP3R1
Mean 37.1
Standard deviation 5.2
Values 33 41
[70]
liver PPP3R1
Mean 8.35
Standard deviation 5.9
Values 3.5 14 3 13
[71]
ref_hepatocyte BID
Mean 12.3
Standard deviation 4.8
Values 4.5 12 17 15 12
[72]
HepG2 BID
Mean 22.5
Standard deviation 0.74
Values 22 23
[73]
HepG2.C3A BID
Mean 21.5
Standard deviation 4.7
Values 18 25
[74]
HuH.7 BID
Mean 15.9
Standard deviation 4.6
Values 15 12 21
[75]
SNU475 BID
Mean 18.5
Standard deviation 1.4
Values 19 17
[76]
THLE BID
Mean 14.3
Standard deviation 1.7
Values 13 15
[77]
liver BID
Mean 19.7
Standard deviation 11
Values 30 9.4 29 10
[78]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[79]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[80]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[81]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[82]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[83]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[84]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[85]
ref_hepatocyte PPP3CC
Mean 3.74
Standard deviation 2.3
Values 3 4.2 7.4 2.6 1.4
[86]
HepG2 PPP3CC
Mean 5.07
Standard deviation 0.34
Values 5.3 4.8
[87]
HepG2.C3A PPP3CC
Mean 4.97
Standard deviation 0.61
Values 5.4 4.5
[88]
HuH.7 PPP3CC
Mean 3.62
Standard deviation 1.2
Values 2.6 5 3.3
[89]
SNU475 PPP3CC
Mean 3.23
Standard deviation 0.21
Values 3.4 3.1
[90]
THLE PPP3CC
Mean 6.83
Standard deviation 0.085
Values 6.9 6.8
[91]
liver PPP3CC
Mean 5.52
Standard deviation 0.57
Values 6.1 5.9 4.8 5.3
[92]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.83 0.16 0.41
[93]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[94]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[95]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[96]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[97]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[98]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 2.8 12 2.3 9.4
[99]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.019 0 0.15 0.12 0.2
[100]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.034 0.026
[101]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 1.3 0.99
[102]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[103]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.55 0.68
[104]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[105]
liver BCL2
Mean 1.31
Standard deviation 1
Values 0.49 1.8 0.49 2.5