REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RPA2 Replication protein A 32 kDa subunit [1] -2.45[2] -2.52[3] -2.50[4] -1.75[5] -2.15[6] -2.23[7]
2 MCM7 DNA replication licensing factor MCM7 [8] 0.92[9] 0.57[10] 1.26[11] 0.28[12] 0.36[13] -0.63[14]
3 MCM3 DNA replication licensing factor MCM3 [15] 1.31[16] 1.01[17] 0.59[18] -0.02[19] 0.59[20] -0.52[21]
4 CDK2 Cyclin-dependent kinase 2 [22] -1.41[23] -1.38[24] -1.55[25] -1.02[26] -0.91[27] -2.02[28]
5 RFC4 Replication factor C subunit 4 [29] -1.96[30] -1.48[31] -1.44[32] -1.97[33] -1.12[34] -2.59[35]
6 MCM4 DNA replication licensing factor MCM4 [36] 1.07[37] 0.81[38] 0.99[39] 0.99[40] 1.16[41] -0.82[42]
7 RFC2 Replication factor C subunit 2 [43] -1.26[44] -1.54[45] -2.04[46] -0.83[47] -0.84[48] -0.61[49]
8 MCM5 DNA replication licensing factor MCM5 [50] 0.22[51] -0.05[52] 0.04[53] -0.49[54] -0.04[55] -0.75[56]
9 RPA1 Replication protein A 70 kDa DNA-binding subunit [57] 0.32[58] -0.09[59] -0.35[60] 0.85[61] 0.39[62] 0.17[63]
10 RPA3 Replication protein A 14 kDa subunit [64] -1.36[65] -0.70[66] -0.52[67] -1.91[68] -2.10[69] -0.53[70]
11 ORC4 Origin recognition complex subunit 4 [71] -0.94[72] 0.10[73] -0.71[74] 0.37[75] -0.86[76] 3.14[77]
12 RAD17 Cell cycle checkpoint protein RAD17 [78] -1.84[79] -0.90[80] -1.39[81] -1.35[82] -1.47[83] -0.27[84]
13 ORC5 Origin recognition complex subunit 5 [85] -1.97[86] -1.77[87] -1.73[88] -1.15[89] -1.86[90] -0.01[91]
14 RFC5 Replication factor C subunit 5 [92] -0.86[93] -0.55[94] -0.89[95] -0.74[96] -0.68[97] -0.71[98]
15 ORC2 Origin recognition complex subunit 2 [99] -0.53[100] 0.28[101] -0.53[102] -0.70[103] -0.89[104] -0.27[105]
16 CDC6 Cell division control protein 6 homolog [106] 0.87[107] 0.29[108] 0.36[109] 0.56[110] 0.35[111] -1.90[112]
17 ORC6 Origin recognition complex subunit 6 [113] -0.24[114] 0.18[115] -1.13[116] -0.22[117] -0.45[118] -3.53[119]
18 MCM6 DNA replication licensing factor MCM6 [120] 0.20[121] -0.22[122] 1.25[123] 1.42[124] 1.73[125] -1.12[126]
19 MCM2 DNA replication licensing factor MCM2 [127] 1.93[128] 1.24[129] 1.99[130] 1.12[131] 1.66[132] -1.45[133]
20 ORC3 Origin recognition complex subunit 3 [134] -0.91[135] 0.15[136] -0.25[137] -0.46[138] 0.03[139] 0.42[140]
21 RFC3 Replication factor C subunit 3 [141] 0.18[142] 0.90[143] 0.50[144] 0.25[145] 0.37[146] -0.70[147]
22 HUS1 Checkpoint protein HUS1 [148] -1.71[149] -1.58[150] -1.58[151] -1.11[152] -1.79[153] 1.54[154]
23 CDC45 Cell division control protein 45 homolog [155] 0.21[156] 0.01[157] 0.14[158] 0.25[159] 0.12[160] -2.74[161]
24 CHEK1 Serine/threonine-protein kinase Chk1 [162] 0.54[163] 0.76[164] -0.21[165] 1.15[166] 0.90[167] -1.86[168]
25 CDC25A M-phase inducer phosphatase 1 [169] 0.43[170] 0.92[171] 0.74[172] -0.66[173] 0.32[174] -2.49[175]
26 RAD1 Cell cycle checkpoint protein RAD1 [176] 0.37[177] 0.91[178] 0.90[179] 0.80[180] 1.22[181] 1.07[182]
27 RAD9A Cell cycle checkpoint control protein RAD9A [183] -0.92[184] -0.78[185] 0.49[186] 1.32[187] -1.33[188] -0.01[189]
28 DBF4 Protein DBF4 homolog A [190] -0.50[191] 1.00[192] 0.19[193] 0.58[194] 0.37[195] -0.30[196]
29 MCM8 DNA helicase MCM8 [197] 1.20[198] 1.77[199] 0.52[200] 1.60[201] 0.67[202] -0.20[203]
30 ATRIP ATR-interacting protein [204] -0.75[205] -0.65[206] -0.31[207] -1.35[208] -0.75[209] 0.00[210]
31 ORC1 Origin recognition complex subunit 1 [211] 0.55[212] 0.45[213] 1.41[214] 0.27[215] 0.36[216] -1.94[217]
32 ATR Serine/threonine-protein kinase ATR [218] 0.10[219] 0.96[220] 0.50[221] 1.52[222] 1.01[223] 3.71[224]
33 CLSPN Claspin [225] 0.36[226] 0.65[227] 0.39[228] 1.74[229] 1.66[230] -0.97[231]
34 CDC7 Cell division cycle 7-related protein kinase [232] -0.50[233] 0.32[234] 0.60[235] 1.41[236] 1.66[237] -0.62[238]
35 MCM10 Protein MCM10 homolog [239] 1.52[240] 2.01[241] 1.13[242] 2.68[243] 1.74[244] -1.46[245]
36 CDC25C M-phase inducer phosphatase 3 [246] 0.94[247] 1.95[248] 1.44[249] 0.92[250] 1.30[251] -1.25[252]
37 RAD9B Cell cycle checkpoint control protein RAD9B [253] -4.33[254] -1.27[255] -2.50[256] -0.57[257] -1.71[258] -0.62[259]
[1]
ref_hepatocyte RPA2
Mean 23.6
Standard deviation 12
Values 23 41 28 15 11
[2]
HepG2 RPA2
Mean 19
Standard deviation 3.9
Values 16 22
[3]
HepG2.C3A RPA2
Mean 17.8
Standard deviation 8.2
Values 12 24
[4]
HuH.7 RPA2
Mean 25.2
Standard deviation 11
Values 27 14 35
[5]
SNU475 RPA2
Mean 25.9
Standard deviation 7.9
Values 20 31
[6]
THLE RPA2
Mean 30.6
Standard deviation 2.7
Values 29 33
[7]
liver RPA2
Mean 6.36
Standard deviation 3.6
Values 6.9 4.2 11 3.2
[8]
ref_hepatocyte MCM7
Mean 13.4
Standard deviation 7.2
Values 15 25 12 8.9 6.7
[9]
HepG2 MCM7
Mean 112
Standard deviation 0.92
Values 1.1e+02 1.1e+02
[10]
HepG2.C3A MCM7
Mean 86.1
Standard deviation 36
Values 61 1.1e+02
[11]
HuH.7 MCM7
Mean 194
Standard deviation 1.1e+02
Values 2.4e+02 70 2.7e+02
[12]
SNU475 MCM7
Mean 60
Standard deviation 16
Values 49 71
[13]
THLE MCM7
Mean 99
Standard deviation 18
Values 86 1.1e+02
[14]
liver MCM7
Mean 10.9
Standard deviation 2.3
Values 13 8.8 13 9.1
[15]
ref_hepatocyte MCM3
Mean 13
Standard deviation 10
Values 30 15 7.4 7.5 5.1
[16]
HepG2 MCM3
Mean 141
Standard deviation 33
Values 1.2e+02 1.6e+02
[17]
HepG2.C3A MCM3
Mean 113
Standard deviation 52
Values 76 1.5e+02
[18]
HuH.7 MCM3
Mean 117
Standard deviation 69
Values 1.5e+02 38 1.6e+02
[19]
SNU475 MCM3
Mean 47
Standard deviation 14
Values 37 57
[20]
THLE MCM3
Mean 112
Standard deviation 21
Values 97 1.3e+02
[21]
liver MCM3
Mean 11.4
Standard deviation 4
Values 10 12 17 7.2
[22]
ref_hepatocyte CDK2
Mean 12.1
Standard deviation 11
Values 19 28 3.3 5.7 4.6
[23]
HepG2 CDK2
Mean 20
Standard deviation 3.4
Values 18 22
[24]
HepG2.C3A CDK2
Mean 20
Standard deviation 9.1
Values 14 26
[25]
HuH.7 CDK2
Mean 24.9
Standard deviation 12
Values 30 11 33
[26]
SNU475 CDK2
Mean 21.8
Standard deviation 2.6
Values 20 24
[27]
THLE CDK2
Mean 36.9
Standard deviation 5.3
Values 33 41
[28]
liver CDK2
Mean 3.76
Standard deviation 1.3
Values 4.4 2.3 5.2 3.2
[29]
ref_hepatocyte RFC4
Mean 11
Standard deviation 7.9
Values 17 21 9.8 4.7 2.4
[30]
HepG2 RFC4
Mean 12.4
Standard deviation 2.7
Values 10 14
[31]
HepG2.C3A RFC4
Mean 17
Standard deviation 7.7
Values 12 22
[32]
HuH.7 RFC4
Mean 24.4
Standard deviation 12
Values 26 12 35
[33]
SNU475 RFC4
Mean 10.3
Standard deviation 3.5
Values 7.8 13
[34]
THLE RFC4
Mean 29.1
Standard deviation 0.079
Values 29 29
[35]
liver RFC4
Mean 2.31
Standard deviation 1.2
Values 2.3 1.9 4 1
[36]
ref_hepatocyte MCM4
Mean 9.18
Standard deviation 8.6
Values 21 15 5.1 2.3 1.9
[37]
HepG2 MCM4
Mean 84.7
Standard deviation 28
Values 65 1e+02
[38]
HepG2.C3A MCM4
Mean 69.6
Standard deviation 44
Values 39 1e+02
[39]
HuH.7 MCM4
Mean 110
Standard deviation 72
Values 1.6e+02 27 1.5e+02
[40]
SNU475 MCM4
Mean 67.3
Standard deviation 15
Values 57 78
[41]
THLE MCM4
Mean 118
Standard deviation 29
Values 98 1.4e+02
[42]
liver MCM4
Mean 6.6
Standard deviation 2.7
Values 4.8 8.8 9 3.8
[43]
ref_hepatocyte RFC2
Mean 8.95
Standard deviation 3.2
Values 7.3 13 6.2 11 6.5
[44]
HepG2 RFC2
Mean 16.5
Standard deviation 2.8
Values 14 18
[45]
HepG2.C3A RFC2
Mean 13.3
Standard deviation 5.7
Values 9.3 17
[46]
HuH.7 RFC2
Mean 13.1
Standard deviation 6.2
Values 15 6.1 18
[47]
SNU475 RFC2
Mean 18.6
Standard deviation 4.4
Values 16 22
[48]
THLE RFC2
Mean 28.7
Standard deviation 3.4
Values 26 31
[49]
liver RFC2
Mean 7.44
Standard deviation 4.1
Values 10 4.9 11 3.1
[50]
ref_hepatocyte MCM5
Mean 8.67
Standard deviation 4.6
Values 8.3 17 7.2 6.4 4.9
[51]
HepG2 MCM5
Mean 44.4
Standard deviation 5.9
Values 40 49
[52]
HepG2.C3A MCM5
Mean 36.1
Standard deviation 17
Values 24 48
[53]
HuH.7 MCM5
Mean 53.6
Standard deviation 30
Values 74 20 67
[54]
SNU475 MCM5
Mean 22.8
Standard deviation 3.6
Values 20 25
[55]
THLE MCM5
Mean 48.5
Standard deviation 18
Values 36 61
[56]
liver MCM5
Mean 6.52
Standard deviation 2.3
Values 4.8 8.4 8.7 4.2
[57]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 9.2 15 5.5 5.3 6.7
[58]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 39 51
[59]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 26 41
[60]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 47 23 48
[61]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 55 54
[62]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[63]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 12 12 14 9.5
[64]
ref_hepatocyte RPA3
Mean 8.22
Standard deviation 4.8
Values 6.2 7.6 1.9 11 15
[65]
HepG2 RPA3
Mean 14.1
Standard deviation 4
Values 11 17
[66]
HepG2.C3A RPA3
Mean 21.8
Standard deviation 13
Values 13 31
[67]
HuH.7 RPA3
Mean 34.5
Standard deviation 16
Values 35 18 50
[68]
SNU475 RPA3
Mean 8.05
Standard deviation 1.5
Values 9.1 7
[69]
THLE RPA3
Mean 11
Standard deviation 2.9
Values 8.9 13
[70]
liver RPA3
Mean 7.22
Standard deviation 6.1
Values 13 2.4 12 1.4
[71]
ref_hepatocyte ORC4
Mean 7.34
Standard deviation 1.8
Values 9.4 4.6 8.6 6.9 7.2
[72]
HepG2 ORC4
Mean 16.9
Standard deviation 4.9
Values 13 20
[73]
HepG2.C3A ORC4
Mean 34.1
Standard deviation 8.3
Values 28 40
[74]
HuH.7 ORC4
Mean 27
Standard deviation 4
Values 28 31 23
[75]
SNU475 ORC4
Mean 34.9
Standard deviation 3.4
Values 32 37
[76]
THLE ORC4
Mean 23.3
Standard deviation 2.6
Values 25 21
[77]
liver ORC4
Mean 81.8
Standard deviation 55
Values 38 1.4e+02 33 1.2e+02
[78]
ref_hepatocyte RAD17
Mean 6.99
Standard deviation 4.4
Values 11 12 4.2 2.8 4.4
[79]
HepG2 RAD17
Mean 8.57
Standard deviation 1.3
Values 7.6 9.5
[80]
HepG2.C3A RAD17
Mean 16.3
Standard deviation 1.9
Values 15 18
[81]
HuH.7 RAD17
Mean 16.1
Standard deviation 0.43
Values 16 16 17
[82]
SNU475 RAD17
Mean 10.1
Standard deviation 0.83
Values 11 9.5
[83]
THLE RAD17
Mean 14.5
Standard deviation 1.9
Values 16 13
[84]
liver RAD17
Mean 7.36
Standard deviation 2.5
Values 9.1 6.1 9.8 4.4
[85]
ref_hepatocyte ORC5
Mean 6.5
Standard deviation 1.9
Values 3.5 7.8 7.3 8.2 5.7
[86]
HepG2 ORC5
Mean 7.28
Standard deviation 2.2
Values 5.8 8.8
[87]
HepG2.C3A ORC5
Mean 8.23
Standard deviation 4.9
Values 4.8 12
[88]
HuH.7 ORC5
Mean 11.8
Standard deviation 2.5
Values 13 9 14
[89]
SNU475 ORC5
Mean 10.8
Standard deviation 1.4
Values 9.8 12
[90]
THLE ORC5
Mean 10.3
Standard deviation 0.9
Values 9.6 11
[91]
liver ORC5
Mean 8.17
Standard deviation 1.7
Values 7.3 8.1 11 6.7
[92]
ref_hepatocyte RFC5
Mean 5.54
Standard deviation 4.9
Values 13 7.4 0.42 3.6 3.2
[93]
HepG2 RFC5
Mean 13.4
Standard deviation 5.4
Values 9.6 17
[94]
HepG2.C3A RFC5
Mean 16.4
Standard deviation 10
Values 9 24
[95]
HuH.7 RFC5
Mean 18.1
Standard deviation 6.8
Values 23 10 21
[96]
SNU475 RFC5
Mean 12.2
Standard deviation 2.4
Values 11 14
[97]
THLE RFC5
Mean 19.8
Standard deviation 2.4
Values 18 22
[98]
liver RFC5
Mean 4.29
Standard deviation 1.7
Values 4.9 3.5 6.3 2.5
[99]
ref_hepatocyte ORC2
Mean 5.18
Standard deviation 5.6
Values 14 7.4 2.6 0.85 0.94
[100]
HepG2 ORC2
Mean 15.7
Standard deviation 4.5
Values 13 19
[101]
HepG2.C3A ORC2
Mean 27.2
Standard deviation 6.2
Values 23 32
[102]
HuH.7 ORC2
Mean 21.7
Standard deviation 4
Values 24 17 24
[103]
SNU475 ORC2
Mean 11.7
Standard deviation 1.6
Values 13 11
[104]
THLE ORC2
Mean 16.1
Standard deviation 1.1
Values 15 17
[105]
liver ORC2
Mean 5.45
Standard deviation 2.1
Values 6.1 5.5 2.6 7.7
[106]
ref_hepatocyte CDC6
Mean 4.53
Standard deviation 4.6
Values 11 8.2 1.9 1.2 0.8
[107]
HepG2 CDC6
Mean 36.3
Standard deviation 14
Values 26 46
[108]
HepG2.C3A CDC6
Mean 24
Standard deviation 17
Values 12 36
[109]
HuH.7 CDC6
Mean 35
Standard deviation 18
Values 43 15 47
[110]
SNU475 CDC6
Mean 24.6
Standard deviation 9.5
Values 18 31
[111]
THLE CDC6
Mean 33.3
Standard deviation 6.1
Values 29 38
[112]
liver CDC6
Mean 1.54
Standard deviation 0.85
Values 0.42 2.4 2 1.4
[113]
ref_hepatocyte ORC6
Mean 4.29
Standard deviation 5.9
Values 14 6.1 0.59 0.53 0.4
[114]
HepG2 ORC6
Mean 16
Standard deviation 4.8
Values 13 19
[115]
HepG2.C3A ORC6
Mean 21.1
Standard deviation 15
Values 11 32
[116]
HuH.7 ORC6
Mean 11.8
Standard deviation 5.5
Values 12 6.2 17
[117]
SNU475 ORC6
Mean 13.6
Standard deviation 0.87
Values 13 14
[118]
THLE ORC6
Mean 18.1
Standard deviation 2.6
Values 16 20
[119]
liver ORC6
Mean 0.47
Standard deviation 0.32
Values 0.26 0.46 0.92 0.24
[120]
ref_hepatocyte MCM6
Mean 4.29
Standard deviation 3.5
Values 3.7 10 4.3 1.8 1.5
[121]
HepG2 MCM6
Mean 21.7
Standard deviation 9.4
Values 15 28
[122]
HepG2.C3A MCM6
Mean 15.9
Standard deviation 9.1
Values 9.5 22
[123]
HuH.7 MCM6
Mean 61.7
Standard deviation 38
Values 84 18 83
[124]
SNU475 MCM6
Mean 42.1
Standard deviation 6.7
Values 37 47
[125]
THLE MCM6
Mean 81.8
Standard deviation 9.3
Values 75 88
[126]
liver MCM6
Mean 2.49
Standard deviation 1
Values 1.7 3.7 2.9 1.6
[127]
ref_hepatocyte MCM2
Mean 4.21
Standard deviation 3.2
Values 9.4 4.9 3.2 1.5 2.1
[128]
HepG2 MCM2
Mean 70.6
Standard deviation 14
Values 61 81
[129]
HepG2.C3A MCM2
Mean 42.9
Standard deviation 17
Values 31 55
[130]
HuH.7 MCM2
Mean 101
Standard deviation 57
Values 1.4e+02 36 1.3e+02
[131]
SNU475 MCM2
Mean 33.8
Standard deviation 11
Values 26 42
[132]
THLE MCM2
Mean 76.3
Standard deviation 20
Values 62 91
[133]
liver MCM2
Mean 1.95
Standard deviation 1.4
Values 1.1 4 1.8 0.94
[134]
ref_hepatocyte ORC3
Mean 3.83
Standard deviation 0.95
Values 4.8 3 4.9 3.1 3.3
[135]
HepG2 ORC3
Mean 8.96
Standard deviation 5.2
Values 5.3 13
[136]
HepG2.C3A ORC3
Mean 18.4
Standard deviation 9
Values 12 25
[137]
HuH.7 ORC3
Mean 19.5
Standard deviation 5.8
Values 24 13 21
[138]
SNU475 ORC3
Mean 10.2
Standard deviation 0.75
Values 9.7 11
[139]
THLE ORC3
Mean 22.5
Standard deviation 0.42
Values 23 22
[140]
liver ORC3
Mean 6.5
Standard deviation 1.7
Values 6.9 6.4 8.4 4.3
[141]
ref_hepatocyte RFC3
Mean 3.17
Standard deviation 3.1
Values 6.3 6.7 1.4 0.35 1.1
[142]
HepG2 RFC3
Mean 15.8
Standard deviation 7.8
Values 10 21
[143]
HepG2.C3A RFC3
Mean 25.6
Standard deviation 17
Values 14 37
[144]
HuH.7 RFC3
Mean 27.1
Standard deviation 12
Values 35 14 33
[145]
SNU475 RFC3
Mean 13.8
Standard deviation 3.5
Values 11 16
[146]
THLE RFC3
Mean 23.5
Standard deviation 5.4
Values 20 27
[147]
liver RFC3
Mean 2.46
Standard deviation 0.85
Values 2 2.9 3.4 1.5
[148]
ref_hepatocyte HUS1
Mean 3.03
Standard deviation 1.3
Values 1.3 3.5 2 4 4.3
[149]
HepG2 HUS1
Mean 4.07
Standard deviation 1.2
Values 3.2 4.9
[150]
HepG2.C3A HUS1
Mean 4.39
Standard deviation 0.9
Values 3.8 5
[151]
HuH.7 HUS1
Mean 6.13
Standard deviation 0.51
Values 6.5 6.3 5.6
[152]
SNU475 HUS1
Mean 5.15
Standard deviation 0.24
Values 5 5.3
[153]
THLE HUS1
Mean 5.04
Standard deviation 0.88
Values 4.4 5.7
[154]
liver HUS1
Mean 11.1
Standard deviation 2.6
Values 13 8.2 9.7 13
[155]
ref_hepatocyte CDC45
Mean 2.51
Standard deviation 2.5
Values 3.1 6.6 1.3 1.1 0.37
[156]
HepG2 CDC45
Mean 12.8
Standard deviation 2.7
Values 11 15
[157]
HepG2.C3A CDC45
Mean 11
Standard deviation 7.8
Values 5.4 17
[158]
HuH.7 CDC45
Mean 16.7
Standard deviation 12
Values 20 3.6 26
[159]
SNU475 CDC45
Mean 11
Standard deviation 3.8
Values 8.4 14
[160]
THLE CDC45
Mean 15.7
Standard deviation 2.2
Values 14 17
[161]
liver CDC45
Mean 0.476
Standard deviation 0.53
Values 0.16 0.56 1.2 0
[162]
ref_hepatocyte CHEK1
Mean 2.44
Standard deviation 1.9
Values 3.2 5.4 1.9 0.69 0.99
[163]
HepG2 CHEK1
Mean 15.6
Standard deviation 7.2
Values 11 21
[164]
HepG2.C3A CHEK1
Mean 17.9
Standard deviation 12
Values 9.6 26
[165]
HuH.7 CHEK1
Mean 12.7
Standard deviation 5.1
Values 15 6.8 16
[166]
SNU475 CHEK1
Mean 19.9
Standard deviation 4.6
Values 17 23
[167]
THLE CHEK1
Mean 26.2
Standard deviation 4.4
Values 23 29
[168]
liver CHEK1
Mean 0.851
Standard deviation 0.2
Values 0.73 1 1 0.64
[169]
ref_hepatocyte CDC25A
Mean 2.04
Standard deviation 2.5
Values 6.2 2.3 1 0.26 0.37
[170]
HepG2 CDC25A
Mean 12.1
Standard deviation 2.6
Values 10 14
[171]
HepG2.C3A CDC25A
Mean 16.8
Standard deviation 9.8
Values 9.8 24
[172]
HuH.7 CDC25A
Mean 20.5
Standard deviation 10
Values 26 8.6 27
[173]
SNU475 CDC25A
Mean 4.76
Standard deviation 2.1
Values 3.3 6.2
[174]
THLE CDC25A
Mean 14.6
Standard deviation 2.2
Values 13 16
[175]
liver CDC25A
Mean 0.459
Standard deviation 0.38
Values 0.33 1 0.28 0.2
[176]
ref_hepatocyte RAD1
Mean 1.96
Standard deviation 0.26
Values 2.2 2 2.2 1.9 1.5
[177]
HepG2 RAD1
Mean 11.2
Standard deviation 2.3
Values 9.5 13
[178]
HepG2.C3A RAD1
Mean 15.9
Standard deviation 6.5
Values 11 20
[179]
HuH.7 RAD1
Mean 22.1
Standard deviation 5.4
Values 27 16 23
[180]
SNU475 RAD1
Mean 12.6
Standard deviation 1.7
Values 11 14
[181]
THLE RAD1
Mean 26.1
Standard deviation 1.3
Values 27 25
[182]
liver RAD1
Mean 5.22
Standard deviation 0.96
Values 5.2 4.2 6.5 5
[183]
ref_hepatocyte RAD9A
Mean 1.87
Standard deviation 0.75
Values 2 1.5 0.94 3 1.9
[184]
HepG2 RAD9A
Mean 4.33
Standard deviation 0.024
Values 4.3 4.3
[185]
HepG2.C3A RAD9A
Mean 4.7
Standard deviation 0.12
Values 4.6 4.8
[186]
HuH.7 RAD9A
Mean 15.8
Standard deviation 6.3
Values 16 9.4 22
[187]
SNU475 RAD9A
Mean 17.3
Standard deviation 3.3
Values 15 20
[188]
THLE RAD9A
Mean 4.29
Standard deviation 0.62
Values 4.7 3.8
[189]
liver RAD9A
Mean 2.36
Standard deviation 1.1
Values 3.3 1.1 3.2 1.8
[190]
ref_hepatocyte DBF4
Mean 1.77
Standard deviation 1.2
Values 2.9 2.2 2.6 0.47 0.58
[191]
HepG2 DBF4
Mean 5.5
Standard deviation 2.8
Values 3.5 7.5
[192]
HepG2.C3A DBF4
Mean 15.2
Standard deviation 7.5
Values 10 21
[193]
HuH.7 DBF4
Mean 12.2
Standard deviation 2.1
Values 14 9.8 13
[194]
SNU475 DBF4
Mean 9.71
Standard deviation 2.7
Values 7.8 12
[195]
THLE DBF4
Mean 13.1
Standard deviation 0.25
Values 13 13
[196]
liver DBF4
Mean 1.82
Standard deviation 0.62
Values 2.3 1.9 2.1 0.91
[197]
ref_hepatocyte MCM8
Mean 1.68
Standard deviation 1.7
Values 3.8 3.2 0.45 0.49 0.46
[198]
HepG2 MCM8
Mean 16.9
Standard deviation 9.8
Values 10 24
[199]
HepG2.C3A MCM8
Mean 24.7
Standard deviation 16
Values 14 36
[200]
HuH.7 MCM8
Mean 14.5
Standard deviation 7.7
Values 22 6.3 15
[201]
SNU475 MCM8
Mean 18.7
Standard deviation 3.3
Values 16 21
[202]
THLE MCM8
Mean 15.3
Standard deviation 1.1
Values 15 16
[203]
liver MCM8
Mean 1.84
Standard deviation 1.3
Values 0.8 3.4 0.82 2.3
[204]
ref_hepatocyte ATRIP
Mean 1.54
Standard deviation 0.36
Values 1.6 1.6 2 1.4 1.1
[205]
HepG2 ATRIP
Mean 4.04
Standard deviation 0.45
Values 3.7 4.4
[206]
HepG2.C3A ATRIP
Mean 4.26
Standard deviation 1.1
Values 3.5 5.1
[207]
HuH.7 ATRIP
Mean 7.5
Standard deviation 2.3
Values 8.5 4.8 9.2
[208]
SNU475 ATRIP
Mean 2.23
Standard deviation 0.45
Values 1.9 2.5
[209]
THLE ATRIP
Mean 5.29
Standard deviation 1.3
Values 4.4 6.2
[210]
liver ATRIP
Mean 1.96
Standard deviation 0.19
Values 1.9 2.1 1.7 2.2
[211]
ref_hepatocyte ORC1
Mean 1.51
Standard deviation 1.9
Values 4.6 1.8 0.38 0.4 0.31
[212]
HepG2 ORC1
Mean 9.76
Standard deviation 4.5
Values 6.6 13
[213]
HepG2.C3A ORC1
Mean 8.91
Standard deviation 3.7
Values 6.3 11
[214]
HuH.7 ORC1
Mean 24.2
Standard deviation 9.6
Values 31 13 29
[215]
SNU475 ORC1
Mean 6.72
Standard deviation 3.5
Values 4.2 9.2
[216]
THLE ORC1
Mean 11.2
Standard deviation 2.9
Values 9.2 13
[217]
liver ORC1
Mean 0.5
Standard deviation 0.15
Values 0.47 0.56 0.67 0.3
[218]
ref_hepatocyte ATR
Mean 1.48
Standard deviation 0.93
Values 1.5 3.1 0.87 1.1 0.82
[219]
HepG2 ATR
Mean 6.99
Standard deviation 2.6
Values 5.1 8.9
[220]
HepG2.C3A ATR
Mean 12.4
Standard deviation 3
Values 10 15
[221]
HuH.7 ATR
Mean 12.6
Standard deviation 3.2
Values 16 10 11
[222]
SNU475 ATR
Mean 15.7
Standard deviation 0.082
Values 16 16
[223]
THLE ATR
Mean 17.2
Standard deviation 1.5
Values 18 16
[224]
liver ATR
Mean 24.7
Standard deviation 14
Values 13 43 15 28
[225]
ref_hepatocyte CLSPN
Mean 1.25
Standard deviation 1.7
Values 4 1.6 0.23 0.25 0.12
[226]
HepG2 CLSPN
Mean 7.06
Standard deviation 4
Values 4.3 9.9
[227]
HepG2.C3A CLSPN
Mean 8.47
Standard deviation 7.1
Values 3.5 13
[228]
HuH.7 CLSPN
Mean 9.87
Standard deviation 6.4
Values 15 2.7 12
[229]
SNU475 CLSPN
Mean 15.4
Standard deviation 7.1
Values 10 20
[230]
THLE CLSPN
Mean 22.6
Standard deviation 1.9
Values 21 24
[231]
liver CLSPN
Mean 0.804
Standard deviation 0.54
Values 0.35 1.5 0.9 0.44
[232]
ref_hepatocyte CDC7
Mean 1.01
Standard deviation 0.88
Values 2 1.9 0.23 0.75 0.18
[233]
HepG2 CDC7
Mean 3.13
Standard deviation 1.9
Values 1.8 4.5
[234]
HepG2.C3A CDC7
Mean 5.45
Standard deviation 3.7
Values 2.9 8
[235]
HuH.7 CDC7
Mean 9.19
Standard deviation 4.7
Values 12 3.7 12
[236]
SNU475 CDC7
Mean 9.87
Standard deviation 2.9
Values 7.8 12
[237]
THLE CDC7
Mean 18.3
Standard deviation 1.1
Values 17 19
[238]
liver CDC7
Mean 0.829
Standard deviation 0.33
Values 0.59 0.91 1.3 0.56
[239]
ref_hepatocyte MCM10
Mean 0.862
Standard deviation 0.93
Values 2.2 1.4 0.39 0.13 0.15
[240]
HepG2 MCM10
Mean 10.9
Standard deviation 4.5
Values 7.7 14
[241]
HepG2.C3A MCM10
Mean 15
Standard deviation 13
Values 6 24
[242]
HuH.7 MCM10
Mean 11.4
Standard deviation 7.2
Values 16 3 15
[243]
SNU475 MCM10
Mean 20.4
Standard deviation 9.4
Values 14 27
[244]
THLE MCM10
Mean 16.5
Standard deviation 3.6
Values 14 19
[245]
liver MCM10
Mean 0.396
Standard deviation 0.26
Values 0.26 0.66 0.57 0.11
[246]
ref_hepatocyte CDC25C
Mean 0.731
Standard deviation 0.89
Values 2 1.3 0.11 0.078 0.13
[247]
HepG2 CDC25C
Mean 6.16
Standard deviation 0.58
Values 5.7 6.6
[248]
HepG2.C3A CDC25C
Mean 12.2
Standard deviation 6.2
Values 7.8 17
[249]
HuH.7 CDC25C
Mean 12
Standard deviation 5.4
Values 14 5.9 16
[250]
SNU475 CDC25C
Mean 5.11
Standard deviation 0.28
Values 5.3 4.9
[251]
THLE CDC25C
Mean 10.3
Standard deviation 1.8
Values 9 12
[252]
liver CDC25C
Mean 0.389
Standard deviation 0.27
Values 0.45 0.43 0.67 0.013
[253]
ref_hepatocyte RAD9B
Mean 0.157
Standard deviation 0.11
Values 0.31 0.12 0.082 0.22 0.041
[254]
HepG2 RAD9B
Mean 0.0344
Standard deviation 4.6e-05
Values 0.034 0.034
[255]
HepG2.C3A RAD9B
Mean 0.282
Standard deviation 0.11
Values 0.36 0.2
[256]
HuH.7 RAD9B
Mean 0.167
Standard deviation 0.048
Values 0.2 0.19 0.11
[257]
SNU475 RAD9B
Mean 0.388
Standard deviation 0.14
Values 0.49 0.29
[258]
THLE RAD9B
Mean 0.275
Standard deviation 0.013
Values 0.28 0.27
[259]
liver RAD9B
Mean 0.129
Standard deviation 0.052
Values 0.094 0.19 0.077 0.16