REACTOME_ACTIVATED_NTRK3_SIGNALS_THROUGH_RAS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GRB2 Growth factor receptor-bound protein 2 [1] 0.55[2] 0.19[3] 0.10[4] -0.75[5] -0.41[6] 0.08[7]
2 SHC1 SHC-transforming protein 1 [8] 0.52[9] 0.54[10] 0.40[11] 1.35[12] 1.25[13] 0.56[14]
3 NRAS GTPase NRas [15] -0.02[16] 0.22[17] 0.42[18] -0.31[19] -0.31[20] -0.47[21]
4 HRAS GTPase HRas [22] -1.65[23] -2.56[24] -3.56[25] -2.25[26] -2.05[27] -2.88[28]
5 KRAS GTPase KRas [29] -1.16[30] -1.38[31] 0.01[32] -0.50[33] -0.42[34] 0.46[35]
6 SOS1 Son of sevenless homolog 1 [36] -0.74[37] 0.59[38] -0.12[39] -0.46[40] -0.80[41] 0.32[42]
7 NTF3 Neurotrophin-3 [43] -6.52[44] -9.49[45] -1.05[46] -7.63[47] [48] -1.17[49]
8 NTRK3 NT-3 growth factor receptor [50] [51] [52] [53] 2.47[54] -1.66[55] 3.63[56]
[1]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[2]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[3]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[4]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[5]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[6]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[7]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[8]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[9]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[10]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[11]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[12]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[13]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[14]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[15]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[16]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[17]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[18]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[19]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[20]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[21]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[22]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[23]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[24]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[25]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[26]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[27]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[28]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[29]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[30]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[31]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[32]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[33]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[34]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[35]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[36]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[37]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[38]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[39]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[40]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[41]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[42]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[43]
ref_hepatocyte NTF3
Mean 0.991
Standard deviation 1
Values 0 0 2.4 1.1 1.5
[44]
HepG2 NTF3
Mean 0.0372
Standard deviation 0.053
Values 0.074 0
[45]
HepG2.C3A NTF3
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[46]
HuH.7 NTF3
Mean 1.88
Standard deviation 0.92
Values 2.1 0.89 2.7
[47]
SNU475 NTF3
Mean 0.0226
Standard deviation 0.025
Values 0.0046 0.041
[48]
THLE NTF3
Mean 0
Standard deviation 0
Values 0 0
[49]
liver NTF3
Mean 0.724
Standard deviation 0.63
Values 0.78 0.34 1.6 0.19
[50]
ref_hepatocyte NTRK3
Mean 0.0299
Standard deviation 0.054
Values 0 0 0.12 0 0.024
[51]
HepG2 NTRK3
Mean 0
Standard deviation 0
Values 0 0
[52]
HepG2.C3A NTRK3
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 NTRK3
Mean 0
Standard deviation 0
Values 0 0 0
[54]
SNU475 NTRK3
Mean 0.747
Standard deviation 1
Values 1.5 0.015
[55]
THLE NTRK3
Mean 0.0358
Standard deviation 0.017
Values 0.024 0.048
[56]
liver NTRK3
Mean 0.61
Standard deviation 0.92
Values 0.19 0.21 0.051 2