REACTOME_ACTIVATED_NTRK3_SIGNALS_THROUGH_PI3K Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [1] -2.01[2] -1.87[3] -1.00[4] 0.14[5] 0.16[6] 0.72[7]
2 SRC Proto-oncogene tyrosine-protein kinase Src [8] 1.48[9] 1.50[10] 0.27[11] 0.47[12] 0.17[13] -3.13[14]
3 IRS1 Insulin receptor substrate 1 [15] 0.55[16] 0.02[17] 1.22[18] -0.22[19] -0.12[20] -0.17[21]
4 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -1.92[22] -0.26[23] -0.30[24] -0.80[25] -0.07[26] -0.37[27]
5 NTF3 Neurotrophin-3 [28] -7.42[29] -10.16[30] -1.73[31] -8.26[32] [33] -3.24[34]
6 NTRK3 NT-3 growth factor receptor [35] [36] [37] [38] 1.84[39] -2.19[40] 1.56[41]
[1]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[2]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[3]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[4]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[5]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[6]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[7]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[8]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[9]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[10]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[11]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[12]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[13]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[14]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[15]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 4.3 1.5 2.7 2.1 4.7
[16]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 35 23
[17]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 22 13
[18]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 49 48 37
[19]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 15 22
[20]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[21]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 23 18 12 22
[22]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[23]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[24]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[25]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[26]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[27]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[28]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[29]
ref_hepatocyte NTF3
Mean 0.991
Standard deviation 1
Values 0 0 2.4 1.1 1.5
[30]
HepG2 NTF3
Mean 0.0372
Standard deviation 0.053
Values 0.074 0
[31]
HepG2.C3A NTF3
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[32]
HuH.7 NTF3
Mean 1.88
Standard deviation 0.92
Values 2.1 0.89 2.7
[33]
SNU475 NTF3
Mean 0.0226
Standard deviation 0.025
Values 0.0046 0.041
[34]
THLE NTF3
Mean 0
Standard deviation 0
Values 0 0
[35]
liver NTF3
Mean 0.724
Standard deviation 0.63
Values 0.78 0.34 1.6 0.19
[36]
ref_hepatocyte NTRK3
Mean 0.0299
Standard deviation 0.054
Values 0 0 0.12 0 0.024
[37]
HepG2 NTRK3
Mean 0
Standard deviation 0
Values 0 0
[38]
HepG2.C3A NTRK3
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 NTRK3
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 NTRK3
Mean 0.747
Standard deviation 1
Values 1.5 0.015
[41]
THLE NTRK3
Mean 0.0358
Standard deviation 0.017
Values 0.024 0.048
[42]
liver NTRK3
Mean 0.61
Standard deviation 0.92
Values 0.19 0.21 0.051 2