REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_RAS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GRB2 Growth factor receptor-bound protein 2 [1] 0.53[2] 0.17[3] 0.09[4] -0.80[5] -0.46[6] 0.06[7]
2 SHC1 SHC-transforming protein 1 [8] 0.50[9] 0.52[10] 0.39[11] 1.29[12] 1.21[13] 0.54[14]
3 NRAS GTPase NRas [15] -0.03[16] 0.20[17] 0.41[18] -0.36[19] -0.35[20] -0.49[21]
4 HRAS GTPase HRas [22] -1.67[23] -2.57[24] -3.57[25] -2.31[26] -2.09[27] -2.90[28]
5 KRAS GTPase KRas [29] -1.18[30] -1.40[31] 0.00[32] -0.56[33] -0.46[34] 0.44[35]
6 SOS1 Son of sevenless homolog 1 [36] -0.76[37] 0.57[38] -0.13[39] -0.51[40] -0.85[41] 0.30[42]
7 BDNF Brain-derived neurotrophic factor [43] -2.32[44] -5.29[45] -3.57[46] 5.39[47] 4.58[48] 1.86[49]
8 NTRK2 BDNF/NT-3 growth factors receptor [50] [51] [52] [53] [54] [55] [56]
9 NTF4 Neurotrophin-4 [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[2]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[3]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[4]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[5]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[6]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[7]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[8]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[9]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[10]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[11]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[12]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[13]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[14]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[15]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[16]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[17]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[18]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[19]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[20]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[21]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[22]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[23]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[24]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[25]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[26]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[27]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[28]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[29]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[30]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[31]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[32]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[33]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[34]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[35]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[36]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[37]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[38]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[39]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[40]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[41]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[42]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[43]
ref_hepatocyte BDNF
Mean 0.0532
Standard deviation 0.065
Values 0 0 0.095 0.15 0.024
[44]
HepG2 BDNF
Mean 0.0372
Standard deviation 0.0041
Values 0.04 0.034
[45]
HepG2.C3A BDNF
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[46]
HuH.7 BDNF
Mean 0.0177
Standard deviation 0.024
Values 0.0082 0.045 0
[47]
SNU475 BDNF
Mean 10.5
Standard deviation 1.7
Values 9.3 12
[48]
THLE BDNF
Mean 4.97
Standard deviation 1.1
Values 5.7 4.2
[49]
liver BDNF
Mean 0.324
Standard deviation 0.17
Values 0.19 0.57 0.23 0.3
[50]
ref_hepatocyte NTRK2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[51]
HepG2 NTRK2
Mean 0.0201
Standard deviation 0.028
Values 0.04 0
[52]
HepG2.C3A NTRK2
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 NTRK2
Mean 0
Standard deviation 0
Values 0 0 0
[54]
SNU475 NTRK2
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[55]
THLE NTRK2
Mean 0
Standard deviation 0
Values 0 0
[56]
liver NTRK2
Mean 1.46
Standard deviation 0.52
Values 0.89 1.2 1.8 2
[57]
ref_hepatocyte NTF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 NTF4
Mean 0.0243
Standard deviation 0.022
Values 0.04 0.0086
[59]
HepG2.C3A NTF4
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 NTF4
Mean 0.0204
Standard deviation 0.023
Values 0.016 0.045 0
[61]
SNU475 NTF4
Mean 0.0814
Standard deviation 0.029
Values 0.1 0.061
[62]
THLE NTF4
Mean 0.0683
Standard deviation 0.029
Values 0.089 0.048
[63]
liver NTF4
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0