REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_PI3K Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GRB2 Growth factor receptor-bound protein 2 [1] 0.33[2] 0.15[3] 0.01[4] -0.72[5] -0.51[6] -1.39[7]
2 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [8] -1.34[9] -1.23[10] -0.40[11] 0.80[12] 0.59[13] 1.32[14]
3 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -1.24[15] 0.38[16] 0.30[17] -0.14[18] 0.36[19] 0.23[20]
4 GAB1 GRB2-associated-binding protein 1 [21] 0.44[22] 1.51[23] 1.37[24] 0.66[25] 0.82[26] 1.19[27]
5 BDNF Brain-derived neurotrophic factor [28] -2.52[29] -5.31[30] -3.64[31] 5.47[32] 4.53[33] 0.41[34]
6 NTF4 Neurotrophin-4 [35] [36] [37] [38] [39] [40] [41]
7 NTRK2 BDNF/NT-3 growth factors receptor [42] [43] [44] [45] [46] [47] [48]
[1]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[2]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[3]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[4]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[5]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[6]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[7]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[8]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[9]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[10]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[11]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[12]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[13]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[14]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[15]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[16]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[17]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[18]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[19]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[20]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[21]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[22]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 2 0.61 0.33 0.38 0.66
[23]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 2.8 5.8
[24]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[25]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 10 8.1 7.3
[26]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 6.6 4.4
[27]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[28]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 7.1 10 5.3 10
[29]
ref_hepatocyte BDNF
Mean 0.0532
Standard deviation 0.065
Values 0 0 0.095 0.15 0.024
[30]
HepG2 BDNF
Mean 0.0372
Standard deviation 0.0041
Values 0.04 0.034
[31]
HepG2.C3A BDNF
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[32]
HuH.7 BDNF
Mean 0.0177
Standard deviation 0.024
Values 0.0082 0.045 0
[33]
SNU475 BDNF
Mean 10.5
Standard deviation 1.7
Values 9.3 12
[34]
THLE BDNF
Mean 4.97
Standard deviation 1.1
Values 5.7 4.2
[35]
liver BDNF
Mean 0.324
Standard deviation 0.17
Values 0.19 0.57 0.23 0.3
[36]
ref_hepatocyte NTF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[37]
HepG2 NTF4
Mean 0.0243
Standard deviation 0.022
Values 0.04 0.0086
[38]
HepG2.C3A NTF4
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 NTF4
Mean 0.0204
Standard deviation 0.023
Values 0.016 0.045 0
[40]
SNU475 NTF4
Mean 0.0814
Standard deviation 0.029
Values 0.1 0.061
[41]
THLE NTF4
Mean 0.0683
Standard deviation 0.029
Values 0.089 0.048
[42]
liver NTF4
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[43]
ref_hepatocyte NTRK2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[44]
HepG2 NTRK2
Mean 0.0201
Standard deviation 0.028
Values 0.04 0
[45]
HepG2.C3A NTRK2
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 NTRK2
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 NTRK2
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[48]
THLE NTRK2
Mean 0
Standard deviation 0
Values 0 0
[49]
liver NTRK2
Mean 1.46
Standard deviation 0.52
Values 0.89 1.2 1.8 2