REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_FYN Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAC1 Ras-related C3 botulinum toxin substrate 1 [1] -0.74[2] -0.80[3] -0.29[4] -0.53[5] -0.51[6] -0.21[7]
2 SRC Proto-oncogene tyrosine-protein kinase Src [8] 2.68[9] 2.93[10] 1.73[11] 1.85[12] 1.07[13] -0.10[14]
3 FYN Tyrosine-protein kinase Fyn [15] 0.60[16] -7.74[17] 0.63[18] 0.92[19] 2.49[20] 1.72[21]
4 BDNF Brain-derived neurotrophic factor [22] -2.00[23] -4.51[24] -2.78[25] 6.20[26] 5.00[27] 2.85[28]
5 DOCK3 Dedicator of cytokinesis protein 3 [29] 0.38[30] 0.55[31] 1.25[32] 4.48[33] 0.97[34] 3.77[35]
6 GRIN2B Glutamate receptor ionotropic, NMDA 2B [36] -2.80[37] [38] [39] 0.54[40] -2.23[41] 2.61[42]
7 NTRK2 BDNF/NT-3 growth factors receptor [43] [44] [45] [46] [47] [48] [49]
[1]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[2]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[3]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[4]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[5]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[6]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[7]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[8]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[9]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[10]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[11]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[12]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[13]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[14]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[15]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[16]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[17]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[18]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[19]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[20]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[21]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[22]
ref_hepatocyte BDNF
Mean 0.0532
Standard deviation 0.065
Values 0 0 0.095 0.15 0.024
[23]
HepG2 BDNF
Mean 0.0372
Standard deviation 0.0041
Values 0.04 0.034
[24]
HepG2.C3A BDNF
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[25]
HuH.7 BDNF
Mean 0.0177
Standard deviation 0.024
Values 0.0082 0.045 0
[26]
SNU475 BDNF
Mean 10.5
Standard deviation 1.7
Values 9.3 12
[27]
THLE BDNF
Mean 4.97
Standard deviation 1.1
Values 5.7 4.2
[28]
liver BDNF
Mean 0.324
Standard deviation 0.17
Values 0.19 0.57 0.23 0.3
[29]
ref_hepatocyte DOCK3
Mean 0.0348
Standard deviation 0.037
Values 0.012 0.039 0.098 0.017 0.0081
[30]
HepG2 DOCK3
Mean 0.127
Standard deviation 0.015
Values 0.14 0.12
[31]
HepG2.C3A DOCK3
Mean 0.106
Standard deviation 0.043
Values 0.14 0.075
[32]
HuH.7 DOCK3
Mean 0.189
Standard deviation 0.1
Values 0.074 0.23 0.26
[33]
SNU475 DOCK3
Mean 2.08
Standard deviation 0.79
Values 2.6 1.5
[34]
THLE DOCK3
Mean 0.199
Standard deviation 0.16
Values 0.089 0.31
[35]
liver DOCK3
Mean 0.401
Standard deviation 0.26
Values 0.26 0.24 0.31 0.79
[36]
ref_hepatocyte GRIN2B
Mean 0.0213
Standard deviation 0.039
Values 0 0 0 0.017 0.089
[37]
HepG2 GRIN2B
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[38]
HepG2.C3A GRIN2B
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 GRIN2B
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 GRIN2B
Mean 0.0833
Standard deviation 0.046
Values 0.12 0.051
[41]
THLE GRIN2B
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[42]
liver GRIN2B
Mean 0.11
Standard deviation 0.05
Values 0.12 0.1 0.051 0.17
[43]
ref_hepatocyte NTRK2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[44]
HepG2 NTRK2
Mean 0.0201
Standard deviation 0.028
Values 0.04 0
[45]
HepG2.C3A NTRK2
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 NTRK2
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 NTRK2
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[48]
THLE NTRK2
Mean 0
Standard deviation 0
Values 0 0
[49]
liver NTRK2
Mean 1.46
Standard deviation 0.52
Values 0.89 1.2 1.8 2