REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -0.69[2] | -1.00[3] | -0.79[4] | -0.86[5] | -0.52[6] | -0.28[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.24[16] | -0.25[17] | -0.42[18] | -0.01[19] | -0.14[20] | 0.17[21] |
4 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [22] | 2.19[23] | 1.98[24] | 3.09[25] | 1.39[26] | 2.08[27] | 0.94[28] |
5 | APH1A | Gamma-secretase subunit APH-1A | [29] | 1.44[30] | 1.60[31] | 1.89[32] | 1.65[33] | 1.43[34] | 0.58[35] |
6 | PSENEN | Gamma-secretase subunit PEN-2 | [36] | -0.56[37] | -0.66[38] | -0.12[39] | 0.03[40] | -0.51[41] | -0.47[42] |
7 | NCSTN | Nicastrin | [43] | 2.86[44] | 1.90[45] | 2.12[46] | 3.01[47] | 2.77[48] | 1.98[49] |
8 | NUMB | Protein numb homolog | [50] | 1.07[51] | 2.03[52] | 1.21[53] | 2.19[54] | 2.24[55] | 1.81[56] |
9 | ITCH | E3 ubiquitin-protein ligase Itchy homolog | [57] | 2.86[58] | 3.27[59] | 2.59[60] | 3.45[61] | 2.66[62] | 3.76[63] |
10 | ADAM10 | Disintegrin and metalloproteinase domain-containing protein 10 | [64] | 2.49[65] | 2.86[66] | 2.95[67] | 3.20[68] | 3.49[69] | 2.39[70] |
11 | ARRB2 | Beta-arrestin-2 | [71] | 1.68[72] | 1.95[73] | 1.97[74] | 0.60[75] | 1.29[76] | 0.72[77] |
12 | PSEN1 | Presenilin-1 | [78] | 2.57[79] | 2.67[80] | 2.30[81] | 3.17[82] | 2.93[83] | 2.59[84] |
13 | DLK1 | Protein delta homolog 1 | [85] | 2.96[86] | 5.68[87] | -5.55[88] | -6.36[89] | -6.94[90] | -3.17[91] |
14 | ADAM17 | Disintegrin and metalloproteinase domain-containing protein 17 | [92] | 2.19[93] | 1.95[94] | 1.76[95] | 3.66[96] | 2.67[97] | 1.67[98] |
15 | PSEN2 | Presenilin-2 | [99] | 0.82[100] | -0.15[101] | -3.90[102] | 2.00[103] | 0.51[104] | 1.50[105] |
16 | DTX2 | Probable E3 ubiquitin-protein ligase DTX2 | [106] | 1.20[107] | 0.31[108] | 0.17[109] | 1.67[110] | 0.75[111] | 0.85[112] |
17 | MIB2 | E3 ubiquitin-protein ligase MIB2 | [113] | 2.63[114] | 2.96[115] | 2.39[116] | 2.29[117] | 2.47[118] | 1.71[119] |
18 | MIB1 | E3 ubiquitin-protein ligase MIB1 | [120] | 3.01[121] | 4.11[122] | 4.39[123] | 4.84[124] | 3.77[125] | 4.29[126] |
19 | JAG1 | Protein jagged-1 | [127] | 6.29[128] | 4.76[129] | 4.29[130] | 3.43[131] | 1.96[132] | 2.64[133] |
20 | DTX4 | E3 ubiquitin-protein ligase DTX4 | [134] | 2.40[135] | 2.30[136] | 3.58[137] | 2.69[138] | -0.89[139] | 3.98[140] |
21 | DTX1 | E3 ubiquitin-protein ligase DTX1 | [141] | -5.43[142] | -6.49[143] | [144] | -3.89[145] | -5.87[146] | 2.21[147] |
22 | APH1B | Gamma-secretase subunit APH-1B | [148] | 1.28[149] | 1.97[150] | 5.16[151] | 5.01[152] | 3.93[153] | 2.82[154] |
23 | NOTCH1 | Neurogenic locus notch homolog protein 1 | [155] | 3.42[156] | 2.14[157] | 3.54[158] | 4.50[159] | 4.74[160] | 6.23[161] |
24 | ARRB1 | Beta-arrestin-1 | [162] | 5.10[163] | 4.78[164] | 4.14[165] | 4.07[166] | 3.76[167] | 4.86[168] |
25 | DLL4 | Delta-like protein 4 | [169] | 2.26[170] | 2.85[171] | 1.68[172] | -1.21[173] | -0.04[174] | 4.79[175] |
26 | DLL1 | Delta-like protein 1 | [176] | -2.85[177] | -1.77[178] | -1.64[179] | -4.87[180] | 2.11[181] | 4.10[182] |
27 | JAG2 | Protein jagged-2 | [183] | 4.96[184] | 0.89[185] | 5.00[186] | 7.77[187] | 4.82[188] | 3.50[189] |
28 | NEURL1B | E3 ubiquitin-protein ligase NEURL1B | [190] | 4.61[191] | 0.61[192] | 2.75[193] | 6.80[194] | 7.54[195] | 8.12[196] |
29 | NEURL1 | E3 ubiquitin-protein ligase NEURL1 | [197] | [198] | [199] | [200] | [201] | [202] | [203] |
30 | DNER | Delta and Notch-like epidermal growth factor-related receptor | [204] | [205] | [206] | [207] | [208] | [209] | [210] |
31 | CNTN1 | Contactin-1 | [211] | [212] | [213] | [214] | [215] | [216] | [217] |