REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 VAMP2 Vesicle-associated membrane protein 2 [1] -2.32[2] -2.03[3] -2.42[4] -3.12[5] -2.01[6] -1.51[7]
2 PPFIA1 Liprin-alpha-1 [8] 0.63[9] 0.31[10] 0.42[11] 1.53[12] 0.57[13] 0.51[14]
3 UNC13B Protein unc-13 homolog B [15] 0.80[16] 0.83[17] 0.75[18] -2.28[19] -0.37[20] 1.25[21]
4 RAB3A Ras-related protein Rab-3A [22] -1.05[23] -2.18[24] -0.79[25] -3.47[26] -1.96[27] -2.54[28]
5 STX1A Syntaxin-1A [29] -0.03[30] -0.14[31] -2.37[32] -0.06[33] 0.26[34] -2.48[35]
6 STXBP1 Syntaxin-binding protein 1 [36] 0.76[37] 1.09[38] 0.78[39] 1.54[40] 2.71[41] -0.48[42]
7 CPLX1 Complexin-1 [43] -1.89[44] -3.02[45] 1.07[46] -5.55[47] -4.27[48] -1.12[49]
8 PPFIA3 Liprin-alpha-3 [50] 1.75[51] 2.10[52] 1.34[53] -1.76[54] -0.87[55] -1.24[56]
9 SNAP25 Synaptosomal-associated protein 25 [57] -4.47[58] -4.35[59] 0.59[60] -0.20[61] 3.16[62] -0.28[63]
10 SYT1 Synaptotagmin-1 [64] -3.07[65] -3.90[66] 4.00[67] 4.53[68] 2.02[69] 2.90[70]
11 CHAT Choline O-acetyltransferase [71] [72] [73] [74] -0.70[75] [76] [77]
12 PPFIA2 Liprin-alpha-2 [78] 3.21[79] 6.07[80] 4.65[81] -1.94[82] -0.20[83] 5.58[84]
13 SLC5A7 High affinity choline transporter 1 [85] [86] [87] [88] [89] [90] [91]
14 PPFIA4 Liprin-alpha-4 [92] [93] [94] [95] [96] [97] [98]
15 SLC18A3 Vesicular acetylcholine transporter [99] [100] [101] [102] [103] [104] [105]
16 TSPOAP1 Peripheral-type benzodiazepine receptor-associated protein 1 [106] [107] [108] [109] [110] [111] [112]
17 RIMS1 Regulating synaptic membrane exocytosis protein 1 [113] [114] [115] [116] [117] [118] [119]
[1]
ref_hepatocyte VAMP2
Mean 7.38
Standard deviation 2
Values 9.9 5.1 8 8.2 5.7
[2]
HepG2 VAMP2
Mean 6.41
Standard deviation 1.5
Values 7.4 5.4
[3]
HepG2.C3A VAMP2
Mean 7.34
Standard deviation 3
Values 9.5 5.2
[4]
HuH.7 VAMP2
Mean 8.97
Standard deviation 0.78
Values 8.3 8.8 9.8
[5]
SNU475 VAMP2
Mean 9.81
Standard deviation 1.6
Values 11 8.7
[6]
THLE VAMP2
Mean 9.61
Standard deviation 0.14
Values 9.5 9.7
[7]
liver VAMP2
Mean 9.18
Standard deviation 10
Values 22 1 11 1.9
[8]
ref_hepatocyte PPFIA1
Mean 4.38
Standard deviation 1.7
Values 4 5.6 6.7 2.7 2.9
[9]
HepG2 PPFIA1
Mean 29.4
Standard deviation 3.9
Values 27 32
[10]
HepG2.C3A PPFIA1
Mean 22.1
Standard deviation 1.5
Values 23 21
[11]
HuH.7 PPFIA1
Mean 38.2
Standard deviation 5.1
Values 38 43 33
[12]
SNU475 PPFIA1
Mean 146
Standard deviation 15
Values 1.6e+02 1.4e+02
[13]
THLE PPFIA1
Mean 33.9
Standard deviation 4
Values 31 37
[14]
liver PPFIA1
Mean 22.1
Standard deviation 4.2
Values 21 25 16 25
[15]
ref_hepatocyte UNC13B
Mean 3.23
Standard deviation 1.4
Values 2.5 5.5 2.6 3.4 2.1
[16]
HepG2 UNC13B
Mean 24.3
Standard deviation 2.4
Values 23 26
[17]
HepG2.C3A UNC13B
Mean 23.4
Standard deviation 3.3
Values 26 21
[18]
HuH.7 UNC13B
Mean 35.5
Standard deviation 5.6
Values 40 37 29
[19]
SNU475 UNC13B
Mean 7.69
Standard deviation 1.6
Values 8.8 6.5
[20]
THLE UNC13B
Mean 13
Standard deviation 0.26
Values 13 13
[21]
liver UNC13B
Mean 27.3
Standard deviation 11
Values 17 41 19 33
[22]
ref_hepatocyte RAB3A
Mean 0.786
Standard deviation 0.29
Values 0.95 0.55 0.49 0.76 1.2
[23]
HepG2 RAB3A
Mean 1.64
Standard deviation 0.46
Values 2 1.3
[24]
HepG2.C3A RAB3A
Mean 0.703
Standard deviation 0.33
Values 0.93 0.47
[25]
HuH.7 RAB3A
Mean 2.95
Standard deviation 0.48
Values 3.5 2.5 2.8
[26]
SNU475 RAB3A
Mean 0.823
Standard deviation 0.069
Values 0.77 0.87
[27]
THLE RAB3A
Mean 1.06
Standard deviation 0.15
Values 1.2 0.95
[28]
liver RAB3A
Mean 0.48
Standard deviation 0.46
Values 0.47 0.19 1.1 0.13
[29]
ref_hepatocyte STX1A
Mean 0.672
Standard deviation 0.98
Values 0.23 0.39 2.4 0.095 0.24
[30]
HepG2 STX1A
Mean 2.85
Standard deviation 0.85
Values 3.4 2.2
[31]
HepG2.C3A STX1A
Mean 2.48
Standard deviation 0.71
Values 3 2
[32]
HuH.7 STX1A
Mean 0.845
Standard deviation 0.25
Values 0.57 0.91 1.1
[33]
SNU475 STX1A
Mean 7.45
Standard deviation 3.6
Values 4.9 10
[34]
THLE STX1A
Mean 4.19
Standard deviation 1.3
Values 5.1 3.3
[35]
liver STX1A
Mean 0.426
Standard deviation 0.18
Values 0.35 0.31 0.69 0.34
[36]
ref_hepatocyte STXBP1
Mean 0.658
Standard deviation 0.63
Values 1.7 0.64 0.69 0.22 0.065
[37]
HepG2 STXBP1
Mean 4.83
Standard deviation 0.73
Values 5.4 4.3
[38]
HepG2.C3A STXBP1
Mean 5.71
Standard deviation 0.79
Values 6.3 5.1
[39]
HuH.7 STXBP1
Mean 7.36
Standard deviation 1.4
Values 8.9 6.5 6.7
[40]
SNU475 STXBP1
Mean 22.1
Standard deviation 0.72
Values 23 22
[41]
THLE STXBP1
Mean 22.4
Standard deviation 6
Values 18 27
[42]
liver STXBP1
Mean 1.67
Standard deviation 0.8
Values 2 1.1 2.6 0.91
[43]
ref_hepatocyte CPLX1
Mean 0.58
Standard deviation 0.61
Values 0.11 0 0.34 1.1 1.4
[44]
HepG2 CPLX1
Mean 0.678
Standard deviation 0.18
Values 0.8 0.55
[45]
HepG2.C3A CPLX1
Mean 0.29
Standard deviation 0.016
Values 0.3 0.28
[46]
HuH.7 CPLX1
Mean 7.91
Standard deviation 0.96
Values 9 7.3 7.4
[47]
SNU475 CPLX1
Mean 0.143
Standard deviation 0.012
Values 0.13 0.15
[48]
THLE CPLX1
Mean 0.156
Standard deviation 0.063
Values 0.2 0.11
[49]
liver CPLX1
Mean 0.943
Standard deviation 0.4
Values 0.73 1.3 0.49 1.3
[50]
ref_hepatocyte PPFIA3
Mean 0.55
Standard deviation 0.41
Values 1.1 0 0.71 0.53 0.39
[51]
HepG2 PPFIA3
Mean 8
Standard deviation 2.9
Values 10 6
[52]
HepG2.C3A PPFIA3
Mean 9.56
Standard deviation 2.5
Values 11 7.8
[53]
HuH.7 PPFIA3
Mean 9.06
Standard deviation 0.25
Values 9.3 9 8.8
[54]
SNU475 PPFIA3
Mean 1.88
Standard deviation 0.44
Values 1.6 2.2
[55]
THLE PPFIA3
Mean 1.58
Standard deviation 0.29
Values 1.8 1.4
[56]
liver PPFIA3
Mean 0.826
Standard deviation 0.32
Values 1 0.4 1.1 0.77
[57]
ref_hepatocyte SNAP25
Mean 0.146
Standard deviation 0.17
Values 0 0 0.3 0.069 0.36
[58]
HepG2 SNAP25
Mean 0.0286
Standard deviation 0.032
Values 0.0057 0.051
[59]
HepG2.C3A SNAP25
Mean 0.0292
Standard deviation 0.041
Values 0.058 0
[60]
HuH.7 SNAP25
Mean 1.43
Standard deviation 0.14
Values 1.4 1.3 1.6
[61]
SNU475 SNAP25
Mean 1.47
Standard deviation 0.63
Values 1 1.9
[62]
THLE SNAP25
Mean 6.82
Standard deviation 0.47
Values 7.1 6.5
[63]
liver SNAP25
Mean 0.427
Standard deviation 0.11
Values 0.42 0.34 0.36 0.58
[64]
ref_hepatocyte SYT1
Mean 0.0375
Standard deviation 0.071
Values 0 0 0.16 0 0.024
[65]
HepG2 SYT1
Mean 0.0193
Standard deviation 0.021
Values 0.034 0.0043
[66]
HepG2.C3A SYT1
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[67]
HuH.7 SYT1
Mean 3.9
Standard deviation 1.6
Values 3.6 5.6 2.5
[68]
SNU475 SYT1
Mean 10
Standard deviation 0.7
Values 9.5 11
[69]
THLE SYT1
Mean 0.793
Standard deviation 0.075
Values 0.85 0.74
[70]
liver SYT1
Mean 0.992
Standard deviation 0.082
Values 0.94 1.1 0.98 0.94
[71]
ref_hepatocyte CHAT
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[72]
HepG2 CHAT
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A CHAT
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 CHAT
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 CHAT
Mean 0.0464
Standard deviation 0.066
Values 0.093 0
[76]
THLE CHAT
Mean 0
Standard deviation 0
Values 0 0
[77]
liver CHAT
Mean 0
Standard deviation 0
Values 0 0 0 0
[78]
ref_hepatocyte PPFIA2
Mean 0.00488
Standard deviation 0.011
Values 0 0 0 0 0.024
[79]
HepG2 PPFIA2
Mean 0.196
Standard deviation 0.026
Values 0.18 0.21
[80]
HepG2.C3A PPFIA2
Mean 1.33
Standard deviation 0.86
Values 1.9 0.72
[81]
HuH.7 PPFIA2
Mean 0.797
Standard deviation 0.16
Values 0.71 0.98 0.7
[82]
SNU475 PPFIA2
Mean 0.0148
Standard deviation 0.0078
Values 0.0093 0.02
[83]
THLE PPFIA2
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[84]
liver PPFIA2
Mean 0.827
Standard deviation 0.62
Values 0.54 0.87 0.23 1.7
[85]
ref_hepatocyte SLC5A7
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 SLC5A7
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A SLC5A7
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 SLC5A7
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 SLC5A7
Mean 0
Standard deviation 0
Values 0 0
[90]
THLE SLC5A7
Mean 0
Standard deviation 0
Values 0 0
[91]
liver SLC5A7
Mean 0.0206
Standard deviation 0.024
Values 0 0.043 0 0.04
[92]
ref_hepatocyte PPFIA4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 PPFIA4
Mean 1.54
Standard deviation 0.4
Values 1.3 1.8
[94]
HepG2.C3A PPFIA4
Mean 1.94
Standard deviation 0.4
Values 1.7 2.2
[95]
HuH.7 PPFIA4
Mean 3.04
Standard deviation 1.1
Values 2.1 4.2 2.9
[96]
SNU475 PPFIA4
Mean 5.33
Standard deviation 1.6
Values 6.5 4.2
[97]
THLE PPFIA4
Mean 2.71
Standard deviation 1.5
Values 3.8 1.6
[98]
liver PPFIA4
Mean 0.136
Standard deviation 0.079
Values 0.19 0.2 0.13 0.026
[99]
ref_hepatocyte SLC18A3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 SLC18A3
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A SLC18A3
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 SLC18A3
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 SLC18A3
Mean 0.299
Standard deviation 0.27
Values 0.49 0.11
[104]
THLE SLC18A3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[105]
liver SLC18A3
Mean 0
Standard deviation 0
Values 0 0 0 0
[106]
ref_hepatocyte TSPOAP1
Missing
[107]
HepG2 TSPOAP1
Missing
[108]
HepG2.C3A TSPOAP1
Missing
[109]
HuH.7 TSPOAP1
Missing
[110]
SNU475 TSPOAP1
Missing
[111]
THLE TSPOAP1
Missing
[112]
liver TSPOAP1
Missing
[113]
ref_hepatocyte RIMS1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 RIMS1
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A RIMS1
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 RIMS1
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 RIMS1
Mean 0.0774
Standard deviation 0.002
Values 0.079 0.076
[118]
THLE RIMS1
Mean 0.0387
Standard deviation 0.013
Values 0.03 0.048
[119]
liver RIMS1
Mean 0.0607
Standard deviation 0.064
Values 0 0.071 0.026 0.15