REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 [1] -6.03[2] -6.55[3] -7.92[4] -7.78[5] -8.11[6] 0.98[7]
2 CHRNA5 Neuronal acetylcholine receptor subunit alpha-5 [8] 1.46[9] 0.98[10] 1.62[11] 1.20[12] 1.72[13] -3.56[14]
3 CHRNE Acetylcholine receptor subunit epsilon [15] -3.33[16] -1.18[17] -3.96[18] -5.25[19] -5.86[20] -1.71[21]
4 CHRNA7 Neuronal acetylcholine receptor subunit alpha-7 [22] 1.91[23] 1.68[24] -1.14[25] 1.50[26] 0.74[27] -2.09[28]
5 CHRNB4 Neuronal acetylcholine receptor subunit beta-4 [29] -4.73[30] -3.34[31] -0.76[32] -3.27[33] -1.40[34] -6.16[35]
6 CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 [36] 1.91[37] 0.97[38] 1.67[39] 0.53[40] 1.61[41] -2.58[42]
7 CHRNA2 Neuronal acetylcholine receptor subunit alpha-2 [43] -0.48[44] 1.08[45] 0.16[46] -4.43[47] -2.03[48] -0.71[49]
8 CHRNB2 Neuronal acetylcholine receptor subunit beta-2 [50] 1.44[51] 2.60[52] 3.76[53] 2.86[54] 1.54[55] 2.96[56]
9 CHRND Acetylcholine receptor subunit delta [57] [58] [59] [60] [61] [62] [63]
10 CHRNG Acetylcholine receptor subunit gamma [64] [65] [66] [67] [68] [69] [70]
11 CHRNA9 Neuronal acetylcholine receptor subunit alpha-9 [71] [72] [73] [74] [75] [76] [77]
12 CHRNB3 Neuronal acetylcholine receptor subunit beta-3 [78] [79] [80] [81] [82] [83] [84]
13 CHRNA6 Neuronal acetylcholine receptor subunit alpha-6 [85] [86] [87] [88] [89] [90] [91]
14 CHRNA1 Acetylcholine receptor subunit alpha [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte CHRNA4
Mean 1.63
Standard deviation 2.3
Values 0 0.041 0.24 2.6 5.3
[2]
HepG2 CHRNA4
Mean 0.0322
Standard deviation 0.027
Values 0.052 0.013
[3]
HepG2.C3A CHRNA4
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[4]
HuH.7 CHRNA4
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[5]
SNU475 CHRNA4
Mean 0.0101
Standard deviation 0.014
Values 0 0.02
[6]
THLE CHRNA4
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[7]
liver CHRNA4
Mean 8.69
Standard deviation 6.8
Values 8.4 3.4 4.5 18
[8]
ref_hepatocyte CHRNA5
Mean 1.01
Standard deviation 0.71
Values 1.9 1.7 0.52 0.53 0.41
[9]
HepG2 CHRNA5
Mean 3.58
Standard deviation 0.27
Values 3.8 3.4
[10]
HepG2.C3A CHRNA5
Mean 2.32
Standard deviation 1.1
Values 1.5 3.1
[11]
HuH.7 CHRNA5
Mean 1.97
Standard deviation 1.2
Values 2.2 0.7 3
[12]
SNU475 CHRNA5
Mean 3.15
Standard deviation 0.92
Values 2.5 3.8
[13]
THLE CHRNA5
Mean 4.98
Standard deviation 1.1
Values 4.2 5.8
[14]
liver CHRNA5
Mean 0.231
Standard deviation 0.046
Values 0.28 0.19 0.26 0.2
[15]
ref_hepatocyte CHRNE
Mean 0.89
Standard deviation 0.71
Values 0.24 0.047 1.6 1.4 1.1
[16]
HepG2 CHRNE
Mean 0.115
Standard deviation 0.0079
Values 0.11 0.12
[17]
HepG2.C3A CHRNE
Mean 0.462
Standard deviation 0.21
Values 0.61 0.31
[18]
HuH.7 CHRNE
Mean 0.0365
Standard deviation 0.025
Values 0.0082 0.045 0.056
[19]
SNU475 CHRNE
Mean 0.0319
Standard deviation 0.012
Values 0.023 0.041
[20]
THLE CHRNE
Mean 0.0231
Standard deviation 0.018
Values 0.035 0.011
[21]
liver CHRNE
Mean 0.736
Standard deviation 0.7
Values 0.33 0.66 1.7 0.21
[22]
ref_hepatocyte CHRNA7
Mean 0.106
Standard deviation 0.19
Values 0.44 0 0 0.086 0
[23]
HepG2 CHRNA7
Mean 0.516
Standard deviation 0.081
Values 0.57 0.46
[24]
HepG2.C3A CHRNA7
Mean 0.399
Standard deviation 0.11
Values 0.48 0.32
[25]
HuH.7 CHRNA7
Mean 0.0306
Standard deviation 0.022
Values 0.016 0.019 0.056
[26]
SNU475 CHRNA7
Mean 0.409
Standard deviation 0.074
Values 0.36 0.46
[27]
THLE CHRNA7
Mean 0.268
Standard deviation 0.12
Values 0.35 0.19
[28]
liver CHRNA7
Mean 0.0671
Standard deviation 0.039
Values 0.024 0.11 0.051 0.079
[29]
ref_hepatocyte CHRNB4
Mean 0.0878
Standard deviation 0.12
Values 0 0.24 0 0.2 0
[30]
HepG2 CHRNB4
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[31]
HepG2.C3A CHRNB4
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[32]
HuH.7 CHRNB4
Mean 0.0332
Standard deviation 0.029
Values 0.0082 0.026 0.066
[33]
SNU475 CHRNB4
Mean 0.0125
Standard deviation 0.011
Values 0.0046 0.02
[34]
THLE CHRNB4
Mean 0.05
Standard deviation 0.012
Values 0.041 0.059
[35]
liver CHRNB4
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[36]
ref_hepatocyte CHRNA3
Mean 0.0464
Standard deviation 0.064
Values 0.12 0.12 0 0 0
[37]
HepG2 CHRNA3
Mean 0.226
Standard deviation 0.26
Values 0.41 0.039
[38]
HepG2.C3A CHRNA3
Mean 0.107
Standard deviation 0.014
Values 0.12 0.097
[39]
HuH.7 CHRNA3
Mean 0.094
Standard deviation 0.032
Values 0.074 0.077 0.13
[40]
SNU475 CHRNA3
Mean 0.0916
Standard deviation 0.064
Values 0.046 0.14
[41]
THLE CHRNA3
Mean 0.214
Standard deviation 0.024
Values 0.23 0.2
[42]
liver CHRNA3
Mean 0.0209
Standard deviation 0.027
Values 0 0.057 0 0.026
[43]
ref_hepatocyte CHRNA2
Mean 0.0401
Standard deviation 0.063
Values 0.14 0 0 0 0.057
[44]
HepG2 CHRNA2
Mean 0.0372
Standard deviation 0.02
Values 0.023 0.051
[45]
HepG2.C3A CHRNA2
Mean 0.0997
Standard deviation 0.065
Values 0.15 0.054
[46]
HuH.7 CHRNA2
Mean 0.0285
Standard deviation 0.011
Values 0.041 0.026 0.019
[47]
SNU475 CHRNA2
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[48]
THLE CHRNA2
Mean 0.0148
Standard deviation 0.021
Values 0.03 0
[49]
liver CHRNA2
Mean 0.066
Standard deviation 0.091
Values 0 0.014 0.051 0.2
[50]
ref_hepatocyte CHRNB2
Mean 0.0159
Standard deviation 0.022
Values 0 0.039 0 0 0.041
[51]
HepG2 CHRNB2
Mean 0.0558
Standard deviation 0.006
Values 0.052 0.06
[52]
HepG2.C3A CHRNB2
Mean 0.113
Standard deviation 0.022
Values 0.097 0.13
[53]
HuH.7 CHRNB2
Mean 0.137
Standard deviation 0.043
Values 0.12 0.19 0.1
[54]
SNU475 CHRNB2
Mean 0.157
Standard deviation 0.086
Values 0.22 0.096
[55]
THLE CHRNB2
Mean 0.0698
Standard deviation 0.0066
Values 0.065 0.074
[56]
liver CHRNB2
Mean 0.334
Standard deviation 0.45
Values 0.071 0.27 0 0.99
[57]
ref_hepatocyte CHRND
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 CHRND
Mean 0.146
Standard deviation 0.085
Values 0.21 0.086
[59]
HepG2.C3A CHRND
Mean 0.919
Standard deviation 0.42
Values 1.2 0.62
[60]
HuH.7 CHRND
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[61]
SNU475 CHRND
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[62]
THLE CHRND
Mean 0
Standard deviation 0
Values 0 0
[63]
liver CHRND
Mean 0.0104
Standard deviation 0.014
Values 0 0.029 0 0.013
[64]
ref_hepatocyte CHRNG
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 CHRNG
Mean 0.0315
Standard deviation 0.02
Values 0.046 0.017
[66]
HepG2.C3A CHRNG
Mean 0.0322
Standard deviation 0.046
Values 0 0.064
[67]
HuH.7 CHRNG
Mean 0.0599
Standard deviation 0.037
Values 0.09 0.071 0.019
[68]
SNU475 CHRNG
Mean 0.0551
Standard deviation 0.021
Values 0.07 0.041
[69]
THLE CHRNG
Mean 0.0195
Standard deviation 0.0025
Values 0.018 0.021
[70]
liver CHRNG
Mean 0.157
Standard deviation 0.17
Values 0 0.29 0.026 0.32
[71]
ref_hepatocyte CHRNA9
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 CHRNA9
Mean 0.0651
Standard deviation 0.035
Values 0.04 0.09
[73]
HepG2.C3A CHRNA9
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 CHRNA9
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[75]
SNU475 CHRNA9
Mean 1.16
Standard deviation 0.6
Values 0.73 1.6
[76]
THLE CHRNA9
Mean 0.101
Standard deviation 0.0076
Values 0.11 0.096
[77]
liver CHRNA9
Mean 0
Standard deviation 0
Values 0 0 0 0
[78]
ref_hepatocyte CHRNB3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 CHRNB3
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[80]
HepG2.C3A CHRNB3
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 CHRNB3
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 CHRNB3
Mean 0
Standard deviation 0
Values 0 0
[83]
THLE CHRNB3
Mean 0
Standard deviation 0
Values 0 0
[84]
liver CHRNB3
Mean 0
Standard deviation 0
Values 0 0 0 0
[85]
ref_hepatocyte CHRNA6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 CHRNA6
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A CHRNA6
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 CHRNA6
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 CHRNA6
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[90]
THLE CHRNA6
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[91]
liver CHRNA6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[92]
ref_hepatocyte CHRNA1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 CHRNA1
Mean 0.135
Standard deviation 0.19
Values 0.27 0
[94]
HepG2.C3A CHRNA1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[95]
HuH.7 CHRNA1
Mean 0.0306
Standard deviation 0.022
Values 0.016 0.019 0.056
[96]
SNU475 CHRNA1
Mean 0.127
Standard deviation 0.12
Values 0.042 0.21
[97]
THLE CHRNA1
Mean 0
Standard deviation 0
Values 0 0
[98]
liver CHRNA1
Mean 0
Standard deviation 0
Values 0 0 0 0