REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOA1 Apolipoprotein A-I [1] -0.35[2] -0.18[3] -0.74[4] -7.84[5] -7.88[6] -0.14[7]
2 ABCD3 ATP-binding cassette sub-family D member 3 [8] 3.73[9] 3.47[10] 5.59[11] 6.03[12] 6.08[13] 2.72[14]
3 PEX19 Peroxisomal biogenesis factor 19 [15] 4.40[16] 3.31[17] 5.22[18] 7.32[19] 7.33[20] 2.40[21]
4 ABCG8 ATP-binding cassette sub-family G member 8 [22] 1.91[23] 1.75[24] -1.73[25] -6.47[26] -5.23[27] 2.79[28]
5 ABCG5 ATP-binding cassette sub-family G member 5 [29] 1.91[30] 2.95[31] -2.09[32] -6.05[33] -3.91[34] 2.83[35]
6 PEX3 Peroxisomal biogenesis factor 3 [36] 4.13[37] 2.87[38] 4.80[39] 6.86[40] 5.88[41] 2.04[42]
7 ABCA6 ATP-binding cassette sub-family A member 6 [43] -4.69[44] -7.20[45] 0.52[46] -5.67[47] 5.44[48] 4.67[49]
8 ABCA5 ATP-binding cassette sub-family A member 5 [50] 3.51[51] 3.30[52] 5.82[53] 5.29[54] 6.29[55] 4.56[56]
9 ABCD1 ATP-binding cassette sub-family D member 1 [57] 6.73[58] 4.77[59] 4.70[60] 7.69[61] 6.89[62] 1.93[63]
10 ABCA2 ATP-binding cassette sub-family A member 2 [64] 7.20[65] 5.83[66] 8.24[67] 9.00[68] 9.26[69] 3.95[70]
11 ABCA9 ATP-binding cassette sub-family A member 9 [71] 0.34[72] -0.13[73] 2.39[74] 1.77[75] 4.81[76] 4.10[77]
12 ABCG1 ATP-binding cassette sub-family G member 1 [78] 2.88[79] -4.19[80] 3.57[81] 0.73[82] 5.95[83] 2.92[84]
13 ABCA3 ATP-binding cassette sub-family A member 3 [85] 5.09[86] 5.45[87] 5.43[88] 9.36[89] 6.38[90] 2.10[91]
14 ABCA7 ATP-binding cassette sub-family A member 7 [92] 8.05[93] 7.95[94] 8.05[95] 8.55[96] 9.72[97] 3.82[98]
15 ABCA10 ATP-binding cassette sub-family A member 10 [99] 4.09[100] 3.57[101] 5.33[102] 6.25[103] 6.75[104] 4.88[105]
16 ABCG4 ATP-binding cassette sub-family G member 4 [106] 2.53[107] [108] 1.78[109] 9.29[110] 10.71[111] 2.47[112]
17 ABCD2 ATP-binding cassette sub-family D member 2 [113] [114] [115] 4.78[116] 10.18[117] 10.93[118] 4.29[119]
18 ABCA12 ATP-binding cassette sub-family A member 12 [120] [121] [122] [123] [124] [125] [126]
[1]
ref_hepatocyte APOA1
Mean 5.54e+03
Standard deviation 5.9e+03
Values 4.7e+03 1.6e+02 9e+02 7.3e+03 1.5e+04
[2]
HepG2 APOA1
Mean 647
Standard deviation 1.1e+02
Values 5.7e+02 7.2e+02
[3]
HepG2.C3A APOA1
Mean 1.4e+03
Standard deviation 4.2e+02
Values 1.7e+03 1.1e+03
[4]
HuH.7 APOA1
Mean 217
Standard deviation 31
Values 1.8e+02 2.4e+02 2.3e+02
[5]
SNU475 APOA1
Mean 0.596
Standard deviation 0.16
Values 0.48 0.71
[6]
THLE APOA1
Mean 0.598
Standard deviation 0.26
Values 0.78 0.41
[7]
liver APOA1
Mean 3.55e+03
Standard deviation 3.2e+03
Values 6.9e+03 8.6e+02 5.7e+03 7.4e+02
[8]
ref_hepatocyte ABCD3
Mean 18.8
Standard deviation 10
Values 26 14 5.3 17 32
[9]
HepG2 ABCD3
Mean 37.1
Standard deviation 21
Values 22 52
[10]
HepG2.C3A ABCD3
Mean 59.7
Standard deviation 22
Values 44 75
[11]
HuH.7 ABCD3
Mean 59.3
Standard deviation 4.4
Values 64 56 57
[12]
SNU475 ABCD3
Mean 30.3
Standard deviation 5.6
Values 34 26
[13]
THLE ABCD3
Mean 32.1
Standard deviation 2.2
Values 31 34
[14]
liver ABCD3
Mean 87.4
Standard deviation 1.3
Values 86 87 88 89
[15]
ref_hepatocyte PEX19
Mean 12.3
Standard deviation 7.3
Values 7.2 7.5 6.5 18 22
[16]
HepG2 PEX19
Mean 38.5
Standard deviation 0.46
Values 39 38
[17]
HepG2.C3A PEX19
Mean 35.1
Standard deviation 4.7
Values 32 38
[18]
HuH.7 PEX19
Mean 30.1
Standard deviation 2.5
Values 32 27 32
[19]
SNU475 PEX19
Mean 48.7
Standard deviation 4.9
Values 52 45
[20]
THLE PEX19
Mean 50.1
Standard deviation 5.9
Values 46 54
[21]
liver PEX19
Mean 46
Standard deviation 11
Values 45 41 61 37
[22]
ref_hepatocyte ABCG8
Mean 8.3
Standard deviation 8.1
Values 5.6 0.83 1.2 17 17
[23]
HepG2 ABCG8
Mean 4.64
Standard deviation 1.2
Values 3.8 5.5
[24]
HepG2.C3A ABCG8
Mean 8.02
Standard deviation 1.9
Values 9.4 6.7
[25]
HuH.7 ABCG8
Mean 0.164
Standard deviation 0.19
Values 0.057 0.38 0.056
[26]
SNU475 ABCG8
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[27]
THLE ABCG8
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[28]
liver ABCG8
Mean 40.7
Standard deviation 8.7
Values 30 40 42 51
[29]
ref_hepatocyte ABCG5
Mean 6.81
Standard deviation 7.7
Values 3.9 0.22 0.43 12 18
[30]
HepG2 ABCG5
Mean 3.81
Standard deviation 0.63
Values 3.4 4.3
[31]
HepG2.C3A ABCG5
Mean 15.1
Standard deviation 4
Values 18 12
[32]
HuH.7 ABCG5
Mean 0.105
Standard deviation 0.098
Values 0.041 0.22 0.056
[33]
SNU475 ABCG5
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[34]
THLE ABCG5
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[35]
liver ABCG5
Mean 34.4
Standard deviation 19
Values 61 18 34 24
[36]
ref_hepatocyte PEX3
Mean 5.69
Standard deviation 1.7
Values 3.3 6.6 4.6 7 7
[37]
HepG2 PEX3
Mean 14.8
Standard deviation 6.1
Values 11 19
[38]
HepG2.C3A PEX3
Mean 12
Standard deviation 4.7
Values 8.6 15
[39]
HuH.7 PEX3
Mean 10.4
Standard deviation 2.3
Values 11 8 12
[40]
SNU475 PEX3
Mean 16.4
Standard deviation 0.64
Values 16 17
[41]
THLE PEX3
Mean 8.5
Standard deviation 0.53
Values 8.9 8.1
[42]
liver PEX3
Mean 16.5
Standard deviation 7
Values 21 14 23 7.8
[43]
ref_hepatocyte ABCA6
Mean 5.21
Standard deviation 6.2
Values 0 1.7 0.82 9.7 14
[44]
HepG2 ABCA6
Mean 0.03
Standard deviation 0.018
Values 0.017 0.043
[45]
HepG2.C3A ABCA6
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[46]
HuH.7 ABCA6
Mean 0.49
Standard deviation 0.38
Values 0.3 0.93 0.24
[47]
SNU475 ABCA6
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[48]
THLE ABCA6
Mean 5.73
Standard deviation 0.48
Values 6.1 5.4
[49]
liver ABCA6
Mean 93.7
Standard deviation 41
Values 66 1.5e+02 64 92
[50]
ref_hepatocyte ABCA5
Mean 3.52
Standard deviation 2.5
Values 5.9 1.2 0.51 5.8 4.2
[51]
HepG2 ABCA5
Mean 5.95
Standard deviation 2.8
Values 4 7.9
[52]
HepG2.C3A ABCA5
Mean 9.98
Standard deviation 0.087
Values 9.9 10
[53]
HuH.7 ABCA5
Mean 13.1
Standard deviation 5
Values 10 19 10
[54]
SNU475 ABCA5
Mean 3.41
Standard deviation 0.74
Values 3.9 2.9
[55]
THLE ABCA5
Mean 6.99
Standard deviation 1.1
Values 7.8 6.2
[56]
liver ABCA5
Mean 58.6
Standard deviation 16
Values 58 68 36 73
[57]
ref_hepatocyte ABCD1
Mean 2.32
Standard deviation 1.2
Values 4.2 1.1 2.6 2.4 1.3
[58]
HepG2 ABCD1
Mean 36.5
Standard deviation 6.2
Values 41 32
[59]
HepG2.C3A ABCD1
Mean 18.2
Standard deviation 4.3
Values 21 15
[60]
HuH.7 ABCD1
Mean 3.94
Standard deviation 0.8
Values 3.7 4.8 3.3
[61]
SNU475 ABCD1
Mean 11.8
Standard deviation 4.2
Values 15 8.8
[62]
THLE ABCD1
Mean 6.97
Standard deviation 0.6
Values 6.5 7.4
[63]
liver ABCD1
Mean 6.26
Standard deviation 1.8
Values 5.9 7.6 3.9 7.6
[64]
ref_hepatocyte ABCA2
Mean 1.2
Standard deviation 0.69
Values 0.69 0.54 0.98 2.2 1.6
[65]
HepG2 ABCA2
Mean 26.3
Standard deviation 14
Values 36 16
[66]
HepG2.C3A ABCA2
Mean 19.7
Standard deviation 7.5
Values 25 14
[67]
HuH.7 ABCA2
Mean 23.9
Standard deviation 3.4
Values 28 22 22
[68]
SNU475 ABCA2
Mean 15.2
Standard deviation 8.1
Values 21 9.5
[69]
THLE ABCA2
Mean 18.8
Standard deviation 1.1
Values 18 20
[70]
liver ABCA2
Mean 13.1
Standard deviation 5.2
Values 9 17 8.3 18
[71]
ref_hepatocyte ABCA9
Mean 0.975
Standard deviation 0.98
Values 0.24 0.4 0.24 1.6 2.4
[72]
HepG2 ABCA9
Mean 0.183
Standard deviation 0.15
Values 0.074 0.29
[73]
HepG2.C3A ABCA9
Mean 0.256
Standard deviation 0.018
Values 0.24 0.27
[74]
HuH.7 ABCA9
Mean 0.336
Standard deviation 0.098
Values 0.29 0.45 0.27
[75]
SNU475 ABCA9
Mean 0.0821
Standard deviation 0.0085
Values 0.088 0.076
[76]
THLE ABCA9
Mean 0.694
Standard deviation 0.2
Values 0.83 0.55
[77]
liver ABCA9
Mean 11.8
Standard deviation 7.7
Values 8.2 22 4.1 13
[78]
ref_hepatocyte ABCG1
Mean 0.617
Standard deviation 0.67
Values 0 0 0.5 1.5 1.1
[79]
HepG2 ABCG1
Mean 0.677
Standard deviation 0.72
Values 1.2 0.17
[80]
HepG2.C3A ABCG1
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[81]
HuH.7 ABCG1
Mean 0.48
Standard deviation 0.39
Values 0.25 0.93 0.26
[82]
SNU475 ABCG1
Mean 0.0253
Standard deviation 0.036
Values 0 0.051
[83]
THLE ABCG1
Mean 0.966
Standard deviation 0.3
Values 1.2 0.76
[84]
liver ABCG1
Mean 3.31
Standard deviation 1.2
Values 1.9 4.6 2.8 3.9
[85]
ref_hepatocyte ABCA3
Mean 0.47
Standard deviation 0.51
Values 0.11 1.3 0.63 0.16 0.15
[86]
HepG2 ABCA3
Mean 2.38
Standard deviation 1.2
Values 3.2 1.5
[87]
HepG2.C3A ABCA3
Mean 5.9
Standard deviation 2.2
Values 7.5 4.3
[88]
HuH.7 ABCA3
Mean 1.33
Standard deviation 0.33
Values 1.2 1.7 1.1
[89]
SNU475 ABCA3
Mean 7.65
Standard deviation 4.2
Values 11 4.7
[90]
THLE ABCA3
Mean 0.994
Standard deviation 0.2
Values 1.1 0.85
[91]
liver ABCA3
Mean 1.42
Standard deviation 0.29
Values 1.5 1.1 1.4 1.8
[92]
ref_hepatocyte ABCA7
Mean 0.367
Standard deviation 0.23
Values 0.65 0.085 0.31 0.53 0.25
[93]
HepG2 ABCA7
Mean 14.5
Standard deviation 6.5
Values 19 9.9
[94]
HepG2.C3A ABCA7
Mean 26.1
Standard deviation 8.5
Values 32 20
[95]
HuH.7 ABCA7
Mean 6.39
Standard deviation 2.8
Values 3.8 9.3 6.1
[96]
SNU475 ABCA7
Mean 3.39
Standard deviation 1.2
Values 4.2 2.5
[97]
THLE ABCA7
Mean 7.84
Standard deviation 1.6
Values 9 6.7
[98]
liver ABCA7
Mean 3.66
Standard deviation 0.57
Values 3.7 3.3 4.4 3.2
[99]
ref_hepatocyte ABCA10
Mean 0.138
Standard deviation 0.13
Values 0.11 0.13 0 0.086 0.36
[100]
HepG2 ABCA10
Mean 0.35
Standard deviation 0.2
Values 0.21 0.49
[101]
HepG2.C3A ABCA10
Mean 0.471
Standard deviation 0.047
Values 0.44 0.5
[102]
HuH.7 ABCA10
Mean 0.364
Standard deviation 0.1
Values 0.25 0.42 0.42
[103]
SNU475 ABCA10
Mean 0.26
Standard deviation 0.027
Values 0.24 0.28
[104]
THLE ABCA10
Mean 0.377
Standard deviation 0.11
Values 0.46 0.3
[105]
liver ABCA10
Mean 2.88
Standard deviation 1.1
Values 2.9 3.6 1.3 3.7
[106]
ref_hepatocyte ABCG4
Mean 0.0216
Standard deviation 0.031
Values 0 0 0 0.043 0.065
[107]
HepG2 ABCG4
Mean 0.0186
Standard deviation 0.014
Values 0.029 0.0086
[108]
HepG2.C3A ABCG4
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 ABCG4
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[110]
SNU475 ABCG4
Mean 0.335
Standard deviation 0.093
Values 0.27 0.4
[111]
THLE ABCG4
Mean 0.919
Standard deviation 0.22
Values 1.1 0.76
[112]
liver ABCG4
Mean 0.0849
Standard deviation 0.067
Values 0.024 0.057 0.18 0.079
[113]
ref_hepatocyte ABCD2
Mean 0.0114
Standard deviation 0.025
Values 0 0 0 0 0.057
[114]
HepG2 ABCD2
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A ABCD2
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 ABCD2
Mean 0.0204
Standard deviation 0.023
Values 0.016 0.045 0
[117]
SNU475 ABCD2
Mean 0.325
Standard deviation 0.027
Values 0.31 0.34
[118]
THLE ABCD2
Mean 0.565
Standard deviation 0.062
Values 0.61 0.52
[119]
liver ABCD2
Mean 0.158
Standard deviation 0.14
Values 0 0.17 0.13 0.33
[120]
ref_hepatocyte ABCA12
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 ABCA12
Mean 0.348
Standard deviation 0.019
Values 0.36 0.33
[122]
HepG2.C3A ABCA12
Mean 0.037
Standard deviation 0.039
Values 0.0097 0.064
[123]
HuH.7 ABCA12
Mean 0.0138
Standard deviation 0.017
Values 0 0.032 0.0094
[124]
SNU475 ABCA12
Mean 0.0169
Standard deviation 0.0024
Values 0.019 0.015
[125]
THLE ABCA12
Mean 0.139
Standard deviation 0.029
Values 0.12 0.16
[126]
liver ABCA12
Mean 0.0383
Standard deviation 0.029
Values 0.071 0.043 0 0.04