REACTOME_ABACAVIR_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ADH1A Alcohol dehydrogenase 1A [1] -11.18[2] [3] -7.06[4] -14.66[5] [6] -1.42[7]
2 PCK1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] [8] -5.14[9] -1.39[10] -9.02[11] [12] -12.81[13] 1.57[14]
3 GUK1 Guanylate kinase [15] 1.69[16] 1.44[17] 0.96[18] 1.89[19] 1.66[20] -1.26[21]
4 NT5C2 Cytosolic purine 5'-nucleotidase [22] 4.48[23] 4.50[24] 5.17[25] 4.10[26] 4.50[27] 0.82[28]
5 ADAL Adenosine deaminase-like protein [29] 4.11[30] 4.22[31] 3.81[32] 4.38[33] 4.50[34] 0.81[35]
[1]
ref_hepatocyte ADH1A
Mean 362
Standard deviation 6e+02
Values 0 0.45 9.8 4.1e+02 1.4e+03
[2]
HepG2 ADH1A
Mean 0.0229
Standard deviation 0.016
Values 0.011 0.034
[3]
HepG2.C3A ADH1A
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 ADH1A
Mean 0.465
Standard deviation 0.75
Values 0.057 1.3 0.0094
[5]
SNU475 ADH1A
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[6]
THLE ADH1A
Mean 0
Standard deviation 0
Values 0 0
[7]
liver ADH1A
Mean 135
Standard deviation 1.5e+02
Values 3.6e+02 47 93 38
[8]
ref_hepatocyte PCK1
Mean 142
Standard deviation 1.9e+02
Values 30 0.041 5.3 4.4e+02 2.4e+02
[9]
HepG2 PCK1
Mean 0.593
Standard deviation 0.35
Values 0.84 0.34
[10]
HepG2.C3A PCK1
Mean 10.1
Standard deviation 5.7
Values 14 6
[11]
HuH.7 PCK1
Mean 0.0471
Standard deviation 0.082
Values 0 0.14 0
[12]
SNU475 PCK1
Mean 0
Standard deviation 0
Values 0 0
[13]
THLE PCK1
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[14]
liver PCK1
Mean 420
Standard deviation 94
Values 3.7e+02 4.8e+02 5.2e+02 3.2e+02
[15]
ref_hepatocyte GUK1
Mean 109
Standard deviation 36
Values 48 1.1e+02 1.3e+02 1.4e+02 1.3e+02
[16]
HepG2 GUK1
Mean 51.7
Standard deviation 4.9
Values 55 48
[17]
HepG2.C3A GUK1
Mean 54.7
Standard deviation 0.073
Values 55 55
[18]
HuH.7 GUK1
Mean 36.6
Standard deviation 8.8
Values 31 32 47
[19]
SNU475 GUK1
Mean 73.3
Standard deviation 24
Values 90 56
[20]
THLE GUK1
Mean 46.2
Standard deviation 2.9
Values 44 48
[21]
liver GUK1
Mean 45.4
Standard deviation 35
Values 74 14 77 16
[22]
ref_hepatocyte NT5C2
Mean 10.7
Standard deviation 5.7
Values 14 19 7.1 6.7 6.3
[23]
HepG2 NT5C2
Mean 35
Standard deviation 8.8
Values 29 41
[24]
HepG2.C3A NT5C2
Mean 44.8
Standard deviation 0.63
Values 45 44
[25]
HuH.7 NT5C2
Mean 66
Standard deviation 5.7
Values 62 73 63
[26]
SNU475 NT5C2
Mean 33.1
Standard deviation 12
Values 42 25
[27]
THLE NT5C2
Mean 32.4
Standard deviation 5.7
Values 28 36
[28]
liver NT5C2
Mean 18.8
Standard deviation 2.6
Values 15 21 21 18
[29]
ref_hepatocyte ADAL
Mean 1.78
Standard deviation 0.62
Values 2.2 2.5 0.91 1.8 1.5
[30]
HepG2 ADAL
Mean 4.52
Standard deviation 1.5
Values 3.5 5.6
[31]
HepG2.C3A ADAL
Mean 6.17
Standard deviation 0.39
Values 5.9 6.4
[32]
HuH.7 ADAL
Mean 4.3
Standard deviation 0.44
Values 4.7 3.8 4.3
[33]
SNU475 ADAL
Mean 6.74
Standard deviation 0.22
Values 6.9 6.6
[34]
THLE ADAL
Mean 5.43
Standard deviation 0.17
Values 5.5 5.3
[35]
liver ADAL
Mean 3.12
Standard deviation 0.44
Values 2.7 3.1 3.7 2.9