KEGG_TRYPTOPHAN_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ALDH2 Aldehyde dehydrogenase, mitochondrial [1] -0.68[2] -1.84[3] -1.37[4] -1.35[5] -1.61[6] -0.91[7]
2 ECHS1 Enoyl-CoA hydratase, mitochondrial [8] -0.42[9] -0.14[10] -0.22[11] -0.92[12] -0.98[13] -0.64[14]
3 ACAT1 Acetyl-CoA acetyltransferase, mitochondrial [15] -0.26[16] -0.65[17] -1.69[18] 0.19[19] -1.18[20] 0.13[21]
4 AOX1 Aldehyde oxidase [22] -1.45[23] -1.90[24] -8.15[25] -2.22[26] -0.85[27] 1.79[28]
5 TDO2 Tryptophan 2,3-dioxygenase [29] -12.49[30] -10.81[31] -7.05[32] -4.80[33] -7.54[34] 0.65[35]
6 CAT Catalase [36] 0.16[37] -0.41[38] 0.23[39] -0.16[40] -1.05[41] 0.03[42]
7 KYNU Kynureninase [43] -0.64[44] -0.33[45] -3.09[46] -1.24[47] -2.32[48] -3.02[49]
8 HADHA Trifunctional enzyme subunit alpha, mitochondrial [50] 2.03[51] 2.07[52] 2.22[53] 1.84[54] 1.84[55] 0.18[56]
9 CYP1A2 Cytochrome P450 1A2 [57] -8.70[58] -7.68[59] -8.19[60] -6.99[61] -7.68[62] -2.11[63]
10 ACAT2 Acetyl-CoA acetyltransferase, cytosolic [64] 0.07[65] 1.82[66] 1.48[67] -0.52[68] -0.26[69] -1.19[70]
11 HAAO 3-hydroxyanthranilate 3,4-dioxygenase [71] -1.29[72] -0.49[73] -2.34[74] -8.04[75] -10.28[76] -1.14[77]
12 ALDH1B1 Aldehyde dehydrogenase X, mitochondrial [78] 1.57[79] 1.25[80] -0.49[81] 0.96[82] 0.17[83] -0.69[84]
13 MAOB Amine oxidase [flavin-containing] B [85] -0.15[86] -0.83[87] -0.02[88] 0.87[89] -7.11[90] -0.45[91]
14 ALDH9A1 4-trimethylaminobutyraldehyde dehydrogenase [92] -0.64[93] -0.15[94] 1.24[95] 1.54[96] 1.43[97] -0.42[98]
15 ALDH3A2 Fatty aldehyde dehydrogenase [99] 2.21[100] 1.85[101] 1.45[102] 2.38[103] 1.25[104] -0.04[105]
16 CYP1A1 Cytochrome P450 1A1 [106] -2.24[107] -4.11[108] -0.30[109] -2.40[110] -3.21[111] -6.25[112]
17 HADH Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [113] -0.17[114] 0.41[115] 0.33[116] 0.20[117] 0.32[118] -0.34[119]
18 GCDH Glutaryl-CoA dehydrogenase, mitochondrial [120] -0.88[121] -0.35[122] 0.34[123] -1.67[124] -0.78[125] -1.24[126]
19 ACMSD 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase [127] -11.71[128] -9.20[129] -2.24[130] -9.04[131] -8.86[132] -1.08[133]
20 EHHADH Peroxisomal bifunctional enzyme [134] -0.66[135] -0.16[136] 0.58[137] -0.14[138] -1.10[139] 1.18[140]
21 AFMID Kynurenine formamidase [141] 1.57[142] 2.54[143] 1.00[144] -1.05[145] -0.77[146] 0.01[147]
22 MAOA Amine oxidase [flavin-containing] A [148] -0.98[149] -0.47[150] 1.94[151] -1.55[152] 3.36[153] 1.05[154]
23 ALDH7A1 Alpha-aminoadipic semialdehyde dehydrogenase [155] 2.87[156] 2.53[157] 2.47[158] 3.02[159] 3.12[160] -0.17[161]
24 DDC Aromatic-L-amino-acid decarboxylase [162] 0.14[163] 1.07[164] 2.62[165] -4.11[166] -5.42[167] -0.29[168]
25 OGDHL 2-oxoglutarate dehydrogenase-like, mitochondrial [169] -1.20[170] -3.45[171] -1.82[172] -0.33[173] -3.13[174] 1.10[175]
26 OGDH 2-oxoglutarate dehydrogenase, mitochondrial [176] 2.96[177] 2.08[178] 3.12[179] 4.13[180] 3.80[181] 0.83[182]
27 AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [183] 0.35[184] 0.30[185] -1.28[186] 0.07[187] 0.21[188] -0.23[189]
28 KMO Kynurenine 3-monooxygenase [190] -6.71[191] -5.35[192] -2.92[193] -0.31[194] -5.55[195] 1.20[196]
29 WARS2 Tryptophan--tRNA ligase, mitochondrial [197] 1.89[198] 2.35[199] 2.49[200] 2.60[201] 2.11[202] -0.52[203]
30 CYP1B1 Cytochrome P450 1B1 [204] -4.83[205] -4.54[206] -0.29[207] 4.60[208] 6.93[209] 0.56[210]
31 ASMT Acetylserotonin O-methyltransferase [211] [212] [213] [214] [215] [216] [217]
32 IDO1 Indoleamine 2,3-dioxygenase 1 [218] 0.85[219] 1.38[220] 0.60[221] 4.82[222] 1.19[223] -0.09[224]
33 IDO2 Indoleamine 2,3-dioxygenase 2 [225] [226] [227] [228] -4.09[229] [230] -0.55[231]
34 IL4I1 L-amino-acid oxidase [232] -2.54[233] -3.72[234] -0.44[235] 2.99[236] 0.65[237] -1.77[238]
35 INMT Indolethylamine N-methyltransferase [239] 1.26[240] 1.72[241] 1.71[242] 4.25[243] 1.44[244] 6.36[245]
36 AANAT Serotonin N-acetyltransferase [246] 1.57[247] 3.84[248] 4.02[249] 4.46[250] 3.69[251] 0.68[252]
37 TPH2 Tryptophan 5-hydroxylase 2 [253] [254] [255] [256] [257] [258] [259]
38 WARS1 [260] [261] [262] [263] [264] [265] [266]
39 TPH1 Tryptophan 5-hydroxylase 1 [267] [268] [269] [270] [271] [272] [273]
40 AOC1 Amiloride-sensitive amine oxidase [copper-containing] [274] [275] [276] [277] [278] [279] [280]
[1]
ref_hepatocyte ALDH2
Mean 413
Standard deviation 5.9e+02
Values 20 27 6.4e+02 22 1.4e+03
[2]
HepG2 ALDH2
Mean 122
Standard deviation 2.9
Values 1.2e+02 1.2e+02
[3]
HepG2.C3A ALDH2
Mean 58.8
Standard deviation 8.6
Values 65 53
[4]
HuH.7 ALDH2
Mean 71
Standard deviation 19
Values 81 49 83
[5]
SNU475 ALDH2
Mean 34.9
Standard deviation 8.2
Values 41 29
[6]
THLE ALDH2
Mean 39.5
Standard deviation 1.8
Values 38 41
[7]
liver ALDH2
Mean 429
Standard deviation 2.9e+02
Values 1.8e+02 7.1e+02 6.5e+02 1.8e+02
[8]
ref_hepatocyte ECHS1
Mean 234
Standard deviation 2.7e+02
Values 50 41 4.2e+02 36 6.2e+02
[9]
HepG2 ECHS1
Mean 82.5
Standard deviation 19
Values 69 96
[10]
HepG2.C3A ECHS1
Mean 108
Standard deviation 1.4
Values 1.1e+02 1.1e+02
[11]
HuH.7 ECHS1
Mean 88.7
Standard deviation 28
Values 93 59 1.1e+02
[12]
SNU475 ECHS1
Mean 26.6
Standard deviation 2.9
Values 29 25
[13]
THLE ECHS1
Mean 34.4
Standard deviation 3
Values 32 37
[14]
liver ECHS1
Mean 293
Standard deviation 2.8e+02
Values 64 6.2e+02 4.2e+02 63
[15]
ref_hepatocyte ACAT1
Mean 166
Standard deviation 1.7e+02
Values 49 47 3.2e+02 23 3.9e+02
[16]
HepG2 ACAT1
Mean 65.7
Standard deviation 6.9
Values 61 71
[17]
HepG2.C3A ACAT1
Mean 53.7
Standard deviation 16
Values 43 65
[18]
HuH.7 ACAT1
Mean 22.9
Standard deviation 6
Values 22 17 29
[19]
SNU475 ACAT1
Mean 40.9
Standard deviation 14
Values 51 31
[20]
THLE ACAT1
Mean 21.3
Standard deviation 4.8
Values 18 25
[21]
liver ACAT1
Mean 353
Standard deviation 1.8e+02
Values 2.4e+02 4.7e+02 5.4e+02 1.6e+02
[22]
ref_hepatocyte AOX1
Mean 166
Standard deviation 2e+02
Values 12 68 2.5e+02 25 4.8e+02
[23]
HepG2 AOX1
Mean 28.7
Standard deviation 3.3
Values 26 31
[24]
HepG2.C3A AOX1
Mean 22.6
Standard deviation 2.4
Values 21 24
[25]
HuH.7 AOX1
Mean 0.258
Standard deviation 0.25
Values 0.16 0.55 0.066
[26]
SNU475 AOX1
Mean 7.67
Standard deviation 6.2
Values 3.3 12
[27]
THLE AOX1
Mean 26.7
Standard deviation 2.8
Values 29 25
[28]
liver AOX1
Mean 1.12e+03
Standard deviation 5.3e+02
Values 1.8e+03 5.6e+02 9.6e+02 1.1e+03
[29]
ref_hepatocyte TDO2
Mean 130
Standard deviation 1.9e+02
Values 0 18 2e+02 5.3 4.3e+02
[30]
HepG2 TDO2
Mean 0.0107
Standard deviation 0.0091
Values 0.017 0.0043
[31]
HepG2.C3A TDO2
Mean 0.037
Standard deviation 0.039
Values 0.0097 0.064
[32]
HuH.7 TDO2
Mean 0.435
Standard deviation 0.39
Values 0.16 0.89 0.26
[33]
SNU475 TDO2
Mean 1.01
Standard deviation 0.68
Values 0.53 1.5
[34]
THLE TDO2
Mean 0.203
Standard deviation 0.19
Values 0.34 0.069
[35]
liver TDO2
Mean 397
Standard deviation 2.8e+02
Values 1.8e+02 7.8e+02 4.4e+02 1.8e+02
[36]
ref_hepatocyte CAT
Mean 121
Standard deviation 1.6e+02
Values 47 18 1.4e+02 6.7 4e+02
[37]
HepG2 CAT
Mean 64.4
Standard deviation 24
Values 48 81
[38]
HepG2.C3A CAT
Mean 46.5
Standard deviation 7.1
Values 41 51
[39]
HuH.7 CAT
Mean 62.9
Standard deviation 3.7
Values 66 59 64
[40]
SNU475 CAT
Mean 23.4
Standard deviation 1.8
Values 25 22
[41]
THLE CAT
Mean 17
Standard deviation 1.1
Values 16 18
[42]
liver CAT
Mean 242
Standard deviation 27
Values 2e+02 2.6e+02 2.5e+02 2.5e+02
[43]
ref_hepatocyte KYNU
Mean 90.5
Standard deviation 1.2e+02
Values 22 3.1e+02 31 70 24
[44]
HepG2 KYNU
Mean 27.4
Standard deviation 17
Values 39 16
[45]
HepG2.C3A KYNU
Mean 36.6
Standard deviation 14
Values 26 47
[46]
HuH.7 KYNU
Mean 4.72
Standard deviation 2.1
Values 3.9 7.1 3.2
[47]
SNU475 KYNU
Mean 8.24
Standard deviation 5.2
Values 4.6 12
[48]
THLE KYNU
Mean 5.29
Standard deviation 2.8
Values 7.2 3.3
[49]
liver KYNU
Mean 21.7
Standard deviation 3.4
Values 18 26 22 21
[50]
ref_hepatocyte HADHA
Mean 82.4
Standard deviation 46
Values 1.4e+02 71 1.1e+02 20 69
[51]
HepG2 HADHA
Mean 159
Standard deviation 5.6
Values 1.6e+02 1.6e+02
[52]
HepG2.C3A HADHA
Mean 176
Standard deviation 53
Values 2.1e+02 1.4e+02
[53]
HuH.7 HADHA
Mean 170
Standard deviation 6.3
Values 1.8e+02 1.7e+02 1.6e+02
[54]
SNU475 HADHA
Mean 63.8
Standard deviation 14
Values 74 54
[55]
THLE HADHA
Mean 86
Standard deviation 10
Values 79 93
[56]
liver HADHA
Mean 182
Standard deviation 42
Values 1.5e+02 1.7e+02 2.4e+02 1.6e+02
[57]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.4 18 71 0.97 3e+02
[58]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.052 0.13
[59]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.24 0.15
[60]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.11 0.1 0.15
[61]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.07 0.2
[62]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[63]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 12 55 58 19
[64]
ref_hepatocyte ACAT2
Mean 68.2
Standard deviation 50
Values 1.5e+02 51 49 17 76
[65]
HepG2 ACAT2
Mean 33.9
Standard deviation 23
Values 18 50
[66]
HepG2.C3A ACAT2
Mean 123
Standard deviation 6.4
Values 1.3e+02 1.2e+02
[67]
HuH.7 ACAT2
Mean 84.1
Standard deviation 10
Values 82 76 95
[68]
SNU475 ACAT2
Mean 10.3
Standard deviation 0.34
Values 11 10
[69]
THLE ACAT2
Mean 16.6
Standard deviation 3.1
Values 14 19
[70]
liver ACAT2
Mean 58.5
Standard deviation 28
Values 47 48 1e+02 39
[71]
ref_hepatocyte HAAO
Mean 49.4
Standard deviation 65
Values 8.2 3.8 72 9.1 1.5e+02
[72]
HepG2 HAAO
Mean 9.61
Standard deviation 2.4
Values 7.9 11
[73]
HepG2.C3A HAAO
Mean 18
Standard deviation 2.2
Values 20 16
[74]
HuH.7 HAAO
Mean 4.33
Standard deviation 0.95
Values 4.8 3.2 4.9
[75]
SNU475 HAAO
Mean 0.0405
Standard deviation 0.021
Values 0.056 0.025
[76]
THLE HAAO
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[77]
liver HAAO
Mean 43.7
Standard deviation 25
Values 21 64 67 23
[78]
ref_hepatocyte ALDH1B1
Mean 46.8
Standard deviation 30
Values 84 73 22 19 36
[79]
HepG2 ALDH1B1
Mean 65.8
Standard deviation 15
Values 56 76
[80]
HepG2.C3A ALDH1B1
Mean 56.7
Standard deviation 1.3
Values 56 58
[81]
HuH.7 ALDH1B1
Mean 14.8
Standard deviation 4.6
Values 18 9.5 17
[82]
SNU475 ALDH1B1
Mean 19.6
Standard deviation 10
Values 27 12
[83]
THLE ALDH1B1
Mean 15.3
Standard deviation 3.4
Values 13 18
[84]
liver ALDH1B1
Mean 56.5
Standard deviation 35
Values 31 1.1e+02 57 32
[85]
ref_hepatocyte MAOB
Mean 46.4
Standard deviation 48
Values 20 15 70 6.9 1.2e+02
[86]
HepG2 MAOB
Mean 19.9
Standard deviation 8.1
Values 14 26
[87]
HepG2.C3A MAOB
Mean 13.4
Standard deviation 5.7
Values 9.3 17
[88]
HuH.7 MAOB
Mean 20.3
Standard deviation 0.76
Values 21 21 19
[89]
SNU475 MAOB
Mean 18.4
Standard deviation 15
Values 29 7.7
[90]
THLE MAOB
Mean 0.0976
Standard deviation 0.012
Values 0.089 0.11
[91]
liver MAOB
Mean 66.2
Standard deviation 42
Values 35 1.1e+02 92 26
[92]
ref_hepatocyte ALDH9A1
Mean 45
Standard deviation 33
Values 14 49 53 14 94
[93]
HepG2 ALDH9A1
Mean 13.7
Standard deviation 4.1
Values 11 17
[94]
HepG2.C3A ALDH9A1
Mean 20.8
Standard deviation 1.7
Values 20 22
[95]
HuH.7 ALDH9A1
Mean 47.2
Standard deviation 5.8
Values 43 54 45
[96]
SNU475 ALDH9A1
Mean 28.2
Standard deviation 2.2
Values 30 27
[97]
THLE ALDH9A1
Mean 35.2
Standard deviation 4.8
Values 32 39
[98]
liver ALDH9A1
Mean 65.7
Standard deviation 27
Values 50 78 97 38
[99]
ref_hepatocyte ALDH3A2
Mean 44.1
Standard deviation 25
Values 41 52 44 7.1 76
[100]
HepG2 ALDH3A2
Mean 97
Standard deviation 12
Values 89 1.1e+02
[101]
HepG2.C3A ALDH3A2
Mean 80.8
Standard deviation 15
Values 70 91
[102]
HuH.7 ALDH3A2
Mean 53.4
Standard deviation 2.9
Values 55 55 50
[103]
SNU475 ALDH3A2
Mean 49.4
Standard deviation 7.9
Values 55 44
[104]
THLE ALDH3A2
Mean 30.6
Standard deviation 2.4
Values 29 32
[105]
liver ALDH3A2
Mean 83.6
Standard deviation 21
Values 88 85 1.1e+02 55
[106]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 77 43 17 0.06 82
[107]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 6.2 2.6
[108]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.4 1.2
[109]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 14 17 17
[110]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 0.49 3.1
[111]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[112]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 0.47 1.2 0.92 1.8
[113]
ref_hepatocyte HADH
Mean 40.9
Standard deviation 39
Values 29 9.1 70 2.9 93
[114]
HepG2 HADH
Mean 17.3
Standard deviation 4.6
Values 14 21
[115]
HepG2.C3A HADH
Mean 27.7
Standard deviation 5.6
Values 24 32
[116]
HuH.7 HADH
Mean 22.8
Standard deviation 5.7
Values 23 17 28
[117]
SNU475 HADH
Mean 10.1
Standard deviation 2
Values 12 8.7
[118]
THLE HADH
Mean 14.8
Standard deviation 0.91
Values 14 15
[119]
liver HADH
Mean 62.8
Standard deviation 48
Values 29 1e+02 1e+02 15
[120]
ref_hepatocyte GCDH
Mean 35.5
Standard deviation 31
Values 27 14 49 4.7 82
[121]
HepG2 GCDH
Mean 9.16
Standard deviation 0.58
Values 8.7 9.6
[122]
HepG2.C3A GCDH
Mean 14.3
Standard deviation 0.91
Values 15 14
[123]
HuH.7 GCDH
Mean 20
Standard deviation 9.2
Values 23 9.5 27
[124]
SNU475 GCDH
Mean 2.41
Standard deviation 0.62
Values 2.8 2
[125]
THLE GCDH
Mean 6.01
Standard deviation 1
Values 5.3 6.7
[126]
liver GCDH
Mean 29.4
Standard deviation 20
Values 11 56 34 16
[127]
ref_hepatocyte ACMSD
Mean 35.4
Standard deviation 47
Values 0 1.6 91 3 81
[128]
HepG2 ACMSD
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[129]
HepG2.C3A ACMSD
Mean 0.0307
Standard deviation 0.0021
Values 0.029 0.032
[130]
HuH.7 ACMSD
Mean 3.33
Standard deviation 0.47
Values 3 3.2 3.9
[131]
SNU475 ACMSD
Mean 0.0146
Standard deviation 0.00091
Values 0.014 0.015
[132]
THLE ACMSD
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[133]
liver ACMSD
Mean 32.8
Standard deviation 10
Values 32 35 44 19
[134]
ref_hepatocyte EHHADH
Mean 33.3
Standard deviation 41
Values 13 9 36 4.6 1e+02
[135]
HepG2 EHHADH
Mean 10
Standard deviation 5.1
Values 6.4 14
[136]
HepG2.C3A EHHADH
Mean 15.2
Standard deviation 3.7
Values 13 18
[137]
HuH.7 EHHADH
Mean 22
Standard deviation 3.4
Values 25 19 22
[138]
SNU475 EHHADH
Mean 6.51
Standard deviation 1.9
Values 7.9 5.1
[139]
THLE EHHADH
Mean 4.51
Standard deviation 0.22
Values 4.4 4.7
[140]
liver EHHADH
Mean 147
Standard deviation 40
Values 1e+02 1.9e+02 1.2e+02 1.8e+02
[141]
ref_hepatocyte AFMID
Mean 27.8
Standard deviation 20
Values 41 7.6 51 4.8 35
[142]
HepG2 AFMID
Mean 39
Standard deviation 12
Values 31 47
[143]
HepG2.C3A AFMID
Mean 82.2
Standard deviation 14
Values 92 72
[144]
HuH.7 AFMID
Mean 24.5
Standard deviation 7.7
Values 25 17 32
[145]
SNU475 AFMID
Mean 2.9
Standard deviation 0.18
Values 3 2.8
[146]
THLE AFMID
Mean 4.73
Standard deviation 0.045
Values 4.7 4.8
[147]
liver AFMID
Mean 54.5
Standard deviation 41
Values 23 1.1e+02 54 28
[148]
ref_hepatocyte MAOA
Mean 22.1
Standard deviation 16
Values 3.4 23 34 8.6 41
[149]
HepG2 MAOA
Mean 5.32
Standard deviation 0.22
Values 5.5 5.2
[150]
HepG2.C3A MAOA
Mean 8.16
Standard deviation 2.3
Values 9.8 6.5
[151]
HuH.7 MAOA
Mean 37.5
Standard deviation 10
Values 36 49 28
[152]
SNU475 MAOA
Mean 1.62
Standard deviation 0.75
Values 1.1 2.1
[153]
THLE MAOA
Mean 66.1
Standard deviation 1.4
Values 67 65
[154]
liver MAOA
Mean 88.9
Standard deviation 19
Values 90 1.1e+02 88 65
[155]
ref_hepatocyte ALDH7A1
Mean 17.3
Standard deviation 15
Values 24 6.2 16 1 39
[156]
HepG2 ALDH7A1
Mean 60.1
Standard deviation 16
Values 49 72
[157]
HepG2.C3A ALDH7A1
Mean 51.1
Standard deviation 14
Values 41 61
[158]
HuH.7 ALDH7A1
Mean 42.6
Standard deviation 10
Values 48 31 49
[159]
SNU475 ALDH7A1
Mean 30.3
Standard deviation 10
Values 38 23
[160]
THLE ALDH7A1
Mean 43.7
Standard deviation 3.2
Values 41 46
[161]
liver ALDH7A1
Mean 30
Standard deviation 18
Values 17 50 40 14
[162]
ref_hepatocyte DDC
Mean 16.2
Standard deviation 7.9
Values 20 15 19 3.1 24
[163]
HepG2 DDC
Mean 8.45
Standard deviation 3.2
Values 6.2 11
[164]
HepG2.C3A DDC
Mean 17.3
Standard deviation 4.6
Values 14 21
[165]
HuH.7 DDC
Mean 43.9
Standard deviation 9.4
Values 45 34 53
[166]
SNU475 DDC
Mean 0.201
Standard deviation 0.063
Values 0.25 0.16
[167]
THLE DDC
Mean 0.11
Standard deviation 0.087
Values 0.17 0.048
[168]
liver DDC
Mean 25.7
Standard deviation 11
Values 15 41 19 28
[169]
ref_hepatocyte OGDHL
Mean 12.9
Standard deviation 18
Values 0.62 0.031 25 0.67 38
[170]
HepG2 OGDHL
Mean 2.66
Standard deviation 0.19
Values 2.5 2.8
[171]
HepG2.C3A OGDHL
Mean 0.601
Standard deviation 0.03
Values 0.62 0.58
[172]
HuH.7 OGDHL
Mean 1.62
Standard deviation 0.38
Values 1.7 1.2 1.9
[173]
SNU475 OGDHL
Mean 2.2
Standard deviation 1.1
Values 3 1.5
[174]
THLE OGDHL
Mean 0.429
Standard deviation 0.16
Values 0.54 0.32
[175]
liver OGDHL
Mean 54
Standard deviation 7.3
Values 60 58 54 44
[176]
ref_hepatocyte OGDH
Mean 9.59
Standard deviation 2.6
Values 6.1 11 11 12 7.8
[177]
HepG2 OGDH
Mean 35.5
Standard deviation 0.48
Values 35 36
[178]
HepG2.C3A OGDH
Mean 20.6
Standard deviation 2.9
Values 23 19
[179]
HuH.7 OGDH
Mean 37
Standard deviation 11
Values 47 26 38
[180]
SNU475 OGDH
Mean 36.2
Standard deviation 8.1
Values 42 31
[181]
THLE OGDH
Mean 38.9
Standard deviation 6
Values 35 43
[182]
liver OGDH
Mean 33.2
Standard deviation 11
Values 41 21 26 45
[183]
ref_hepatocyte AADAT
Mean 6.3
Standard deviation 9.1
Values 1.3 1.3 6.3 0.67 22
[184]
HepG2 AADAT
Mean 3.81
Standard deviation 2.5
Values 2 5.6
[185]
HepG2.C3A AADAT
Mean 3.96
Standard deviation 1.1
Values 3.2 4.7
[186]
HuH.7 AADAT
Mean 1.15
Standard deviation 0.46
Values 1.4 0.62 1.5
[187]
SNU475 AADAT
Mean 1.43
Standard deviation 0.11
Values 1.5 1.3
[188]
THLE AADAT
Mean 2.12
Standard deviation 0.11
Values 2 2.2
[189]
liver AADAT
Mean 10.5
Standard deviation 4.6
Values 7.2 16 13 6
[190]
ref_hepatocyte KMO
Mean 3.63
Standard deviation 4.2
Values 0.026 0.95 7.5 0.79 8.8
[191]
HepG2 KMO
Mean 0.0165
Standard deviation 0.0071
Values 0.011 0.021
[192]
HepG2.C3A KMO
Mean 0.0452
Standard deviation 0.018
Values 0.058 0.032
[193]
HuH.7 KMO
Mean 0.212
Standard deviation 0.072
Values 0.17 0.3 0.17
[194]
SNU475 KMO
Mean 0.629
Standard deviation 0.51
Values 0.27 0.99
[195]
THLE KMO
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[196]
liver KMO
Mean 16.3
Standard deviation 7.3
Values 14 27 15 9.6
[197]
ref_hepatocyte WARS2
Mean 3.5
Standard deviation 1.4
Values 5.7 3.9 2.5 2.8 2.6
[198]
HepG2 WARS2
Mean 6.14
Standard deviation 2
Values 4.7 7.5
[199]
HepG2.C3A WARS2
Mean 9.1
Standard deviation 2.7
Values 11 7.2
[200]
HuH.7 WARS2
Mean 8.75
Standard deviation 0.95
Values 8.5 9.8 8
[201]
SNU475 WARS2
Mean 4.59
Standard deviation 1.1
Values 5.4 3.8
[202]
THLE WARS2
Mean 4.4
Standard deviation 0.88
Values 3.8 5
[203]
liver WARS2
Mean 4.75
Standard deviation 1.3
Values 5.5 4 6.1 3.4
[204]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.024 8 2.7 0.92 1.4
[205]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.057 0.03
[206]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.029 0.086
[207]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.87 1 0.95
[208]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 16 11
[209]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[210]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 7.4 6.9 9.5 6.2
[211]
ref_hepatocyte ASMT
Mean 0.657
Standard deviation 0.74
Values 0.29 0.27 1.8 0 0.88
[212]
HepG2 ASMT
Missing
[213]
HepG2.C3A ASMT
Missing
[214]
HuH.7 ASMT
Missing
[215]
SNU475 ASMT
Missing
[216]
THLE ASMT
Missing
[217]
liver ASMT
Missing
[218]
ref_hepatocyte IDO1
Mean 0.512
Standard deviation 0.3
Values 0.8 0.86 0.22 0.35 0.33
[219]
HepG2 IDO1
Mean 0.438
Standard deviation 0.012
Values 0.43 0.45
[220]
HepG2.C3A IDO1
Mean 0.68
Standard deviation 0.23
Values 0.85 0.51
[221]
HuH.7 IDO1
Mean 0.343
Standard deviation 0.071
Values 0.37 0.4 0.26
[222]
SNU475 IDO1
Mean 3.13
Standard deviation 1.9
Values 4.4 1.8
[223]
THLE IDO1
Mean 0.339
Standard deviation 0.014
Values 0.35 0.33
[224]
liver IDO1
Mean 0.937
Standard deviation 0.19
Values 1.1 0.85 0.72 1.1
[225]
ref_hepatocyte IDO2
Mean 0.384
Standard deviation 0.62
Values 0 0 0.49 0 1.4
[226]
HepG2 IDO2
Mean 0
Standard deviation 0
Values 0 0
[227]
HepG2.C3A IDO2
Mean 0
Standard deviation 0
Values 0 0
[228]
HuH.7 IDO2
Mean 0
Standard deviation 0
Values 0 0 0
[229]
SNU475 IDO2
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[230]
THLE IDO2
Mean 0
Standard deviation 0
Values 0 0
[231]
liver IDO2
Mean 0.511
Standard deviation 0.4
Values 0.7 0.12 0.98 0.25
[232]
ref_hepatocyte IL4I1
Mean 0.263
Standard deviation 0.43
Values 0 0 0.078 1 0.22
[233]
HepG2 IL4I1
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[234]
HepG2.C3A IL4I1
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[235]
HuH.7 IL4I1
Mean 0.086
Standard deviation 0.025
Values 0.11 0.058 0.094
[236]
SNU475 IL4I1
Mean 0.452
Standard deviation 0.29
Values 0.25 0.66
[237]
THLE IL4I1
Mean 0.12
Standard deviation 0.011
Values 0.11 0.13
[238]
liver IL4I1
Mean 0.15
Standard deviation 0.14
Values 0.071 0.12 0.36 0.053
[239]
ref_hepatocyte INMT
Mean 0.233
Standard deviation 0.17
Values 0.075 0.37 0.38 0.019 0.33
[240]
HepG2 INMT
Mean 0.265
Standard deviation 0.023
Values 0.28 0.25
[241]
HepG2.C3A INMT
Mean 0.391
Standard deviation 0.099
Values 0.32 0.46
[242]
HuH.7 INMT
Mean 0.338
Standard deviation 0.018
Values 0.33 0.36 0.33
[243]
SNU475 INMT
Mean 0.957
Standard deviation 0.36
Values 1.2 0.7
[244]
THLE INMT
Mean 0.184
Standard deviation 0.049
Values 0.22 0.15
[245]
liver INMT
Mean 37.2
Standard deviation 11
Values 23 50 38 37
[246]
ref_hepatocyte AANAT
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[247]
HepG2 AANAT
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[248]
HepG2.C3A AANAT
Mean 0.0593
Standard deviation 0.054
Values 0.097 0.021
[249]
HuH.7 AANAT
Mean 0.0585
Standard deviation 0.03
Values 0.066 0.026 0.084
[250]
SNU475 AANAT
Mean 0.0386
Standard deviation 0.0044
Values 0.042 0.035
[251]
THLE AANAT
Mean 0.0305
Standard deviation 0.0096
Values 0.024 0.037
[252]
liver AANAT
Mean 0.0253
Standard deviation 0.021
Values 0 0.024 0.051 0.026
[253]
ref_hepatocyte TPH2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[254]
HepG2 TPH2
Mean 0
Standard deviation 0
Values 0 0
[255]
HepG2.C3A TPH2
Mean 0
Standard deviation 0
Values 0 0
[256]
HuH.7 TPH2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[257]
SNU475 TPH2
Mean 0
Standard deviation 0
Values 0 0
[258]
THLE TPH2
Mean 0
Standard deviation 0
Values 0 0
[259]
liver TPH2
Mean 0.00357
Standard deviation 0.0071
Values 0.014 0 0 0
[260]
ref_hepatocyte WARS1
Missing
[261]
HepG2 WARS1
Missing
[262]
HepG2.C3A WARS1
Missing
[263]
HuH.7 WARS1
Missing
[264]
SNU475 WARS1
Missing
[265]
THLE WARS1
Missing
[266]
liver WARS1
Missing
[267]
ref_hepatocyte TPH1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[268]
HepG2 TPH1
Mean 0.0701
Standard deviation 0.01
Values 0.063 0.077
[269]
HepG2.C3A TPH1
Mean 0.269
Standard deviation 0.11
Values 0.19 0.34
[270]
HuH.7 TPH1
Mean 0.0367
Standard deviation 0.025
Values 0.066 0.026 0.019
[271]
SNU475 TPH1
Mean 0.0361
Standard deviation 0.008
Values 0.042 0.03
[272]
THLE TPH1
Mean 0.0911
Standard deviation 0.039
Values 0.12 0.064
[273]
liver TPH1
Mean 0.0508
Standard deviation 0.037
Values 0.086 0 0.051 0.066
[274]
ref_hepatocyte AOC1
Missing
[275]
HepG2 AOC1
Missing
[276]
HepG2.C3A AOC1
Missing
[277]
HuH.7 AOC1
Missing
[278]
SNU475 AOC1
Missing
[279]
THLE AOC1
Missing
[280]
liver AOC1
Missing