KEGG_STEROID_HORMONE_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AKR1C1 Aldo-keto reductase family 1 member C1 [1] 0.37[2] -0.19[3] -1.94[4] -0.38[5] -2.69[6] -3.59[7]
2 HSD17B6 17-beta-hydroxysteroid dehydrogenase type 6 [8] -7.37[9] -7.43[10] -4.53[11] -3.54[12] -4.74[13] 0.32[14]
3 CYP3A4 Cytochrome P450 3A4 [15] -8.62[16] -8.98[17] -8.74[18] -14.04[19] -10.02[20] 1.38[21]
4 AKR1C3 Aldo-keto reductase family 1 member C3 [22] 0.85[23] 1.24[24] -3.45[25] 2.86[26] -1.73[27] -1.54[28]
5 UGT1A6 UDP-glucuronosyltransferase 1-6 [29] -5.71[30] -13.69[31] -5.84[32] -5.39[33] -8.75[34] -3.24[35]
6 UGT2B4 UDP-glucuronosyltransferase 2B4 [36] -6.32[37] -6.74[38] 0.47[39] -8.63[40] -9.64[41] 1.42[42]
7 AKR1C2 Aldo-keto reductase family 1 member C2 [43] 2.24[44] -0.05[45] -0.72[46] 1.97[47] -1.50[48] -0.52[49]
8 CYP3A5 Cytochrome P450 3A5 [50] -3.69[51] -1.70[52] -2.49[53] -6.61[54] -6.35[55] 1.74[56]
9 HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 [57] -10.68[58] -10.77[59] -11.01[60] -6.90[61] 1.60[62] 0.39[63]
10 UGT2B7 UDP-glucuronosyltransferase 2B7 [64] -0.22[65] -0.31[66] -3.82[67] -9.84[68] -8.93[69] 0.13[70]
11 AKR1C4 Aldo-keto reductase family 1 member C4 [71] -5.94[72] -3.82[73] -2.45[74] -8.19[75] -11.20[76] -0.23[77]
12 UGT2B10 UDP-glucuronosyltransferase 2B10 [78] -0.64[79] 1.75[80] -3.95[81] -9.97[82] -10.97[83] -0.96[84]
13 UGT2B15 UDP-glucuronosyltransferase 2B15 [85] -8.56[86] -7.24[87] -4.57[88] -9.71[89] -7.78[90] -0.34[91]
14 UGT1A1 UDP-glucuronosyltransferase 1-1 [92] -3.24[93] -9.73[94] -2.62[95] 0.13[96] -7.39[97] 0.60[98]
15 UGT1A4 UDP-glucuronosyltransferase 1-4 [99] -10.62[100] [101] -8.52[102] -9.14[103] [104] 0.78[105]
16 CYP1A1 Cytochrome P450 1A1 [106] -1.34[107] -3.16[108] 2.45[109] -3.01[110] -1.08[111] -5.15[112]
17 COMT Catechol O-methyltransferase [113] 2.49[114] 2.86[115] 2.64[116] 0.74[117] 3.27[118] 1.01[119]
18 HSD17B2 Estradiol 17-beta-dehydrogenase 2 [120] 0.55[121] 1.76[122] 3.30[123] -7.20[124] -2.93[125] 0.08[126]
19 CYP3A7 Cytochrome P450 3A7 [127] -3.80[128] -1.77[129] -4.54[130] [131] -7.82[132] -1.02[133]
20 AKR1D1 3-oxo-5-beta-steroid 4-dehydrogenase [134] 0.04[135] 1.18[136] 0.43[137] -7.63[138] -5.38[139] 0.37[140]
21 HSD17B8 Estradiol 17-beta-dehydrogenase 8 [141] -0.10[142] 0.44[143] 2.57[144] -3.67[145] -0.15[146] -0.65[147]
22 HSD17B12 Very-long-chain 3-oxoacyl-CoA reductase [148] 1.92[149] 2.94[150] 5.47[151] 0.33[152] 3.89[153] 1.65[154]
23 UGT1A9 UDP-glucuronosyltransferase 1-9 [155] -4.58[156] -9.70[157] -3.93[158] -4.20[159] -6.98[160] 0.01[161]
24 HSD17B7 3-keto-steroid reductase [162] -0.10[163] 1.52[164] 3.50[165] -0.91[166] 1.21[167] -0.14[168]
25 UGT2B17 UDP-glucuronosyltransferase 2B17 [169] -7.90[170] -7.52[171] -8.38[172] [173] [174] -0.71[175]
26 SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [176] 1.11[177] 0.98[178] 3.96[179] 1.41[180] 4.36[181] 1.83[182]
27 UGT2A3 UDP-glucuronosyltransferase 2A3 [183] 4.40[184] 6.03[185] 0.58[186] -4.57[187] -4.93[188] 2.15[189]
28 SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [190] -5.57[191] -4.99[192] -3.10[193] -9.87[194] -7.35[195] 0.38[196]
29 CYP21A2 Steroid 21-hydroxylase [197] -2.74[198] -1.05[199] -3.46[200] -1.75[201] -4.59[202] 0.37[203]
30 UGT1A3 UDP-glucuronosyltransferase 1-3 [204] 0.16[205] [206] -4.78[207] -3.94[208] -6.57[209] 1.89[210]
31 CYP7A1 Cholesterol 7-alpha-monooxygenase [211] -1.22[212] -3.79[213] -5.37[214] -7.49[215] [216] -2.31[217]
32 SRD5A3 Polyprenol reductase [218] 3.78[219] 3.16[220] 5.21[221] 2.45[222] 5.14[223] 1.08[224]
33 SULT1E1 Estrogen sulfotransferase [225] 0.27[226] 2.69[227] 5.13[228] -5.72[229] 5.47[230] 1.73[231]
34 CYP1B1 Cytochrome P450 1B1 [232] -3.92[233] -3.59[234] 2.47[235] 3.98[236] 9.07[237] 1.66[238]
35 HSD17B1 Estradiol 17-beta-dehydrogenase 1 [239] 3.93[240] 4.34[241] 5.69[242] 2.44[243] 4.65[244] 0.22[245]
36 CYP3A43 Cytochrome P450 3A43 [246] -1.73[247] 0.92[248] 2.70[249] [250] -5.19[251] 2.03[252]
37 CYP7B1 25-hydroxycholesterol 7-alpha-hydroxylase [253] -4.91[254] -3.86[255] [256] -6.55[257] -0.35[258] 2.92[259]
38 STS Steryl-sulfatase [260] 3.28[261] 2.50[262] 5.64[263] 1.91[264] 6.56[265] 2.76[266]
39 CYP19A1 Aromatase [267] 5.06[268] 5.84[269] 1.34[270] 0.82[271] 0.85[272] -5.69[273]
40 CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial [274] 2.47[275] -0.29[276] [277] -0.78[278] 5.74[279] 1.12[280]
41 HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 [281] 5.33[282] 5.13[283] 6.24[284] 0.20[285] 0.33[286] 1.29[287]
42 UGT1A5 UDP-glucuronosyltransferase 1-5 [288] -3.12[289] [290] -2.60[291] -0.80[292] [293] 1.95[294]
43 UGT2B11 UDP-glucuronosyltransferase 2B11 [295] 3.34[296] 1.75[297] 4.95[298] -3.80[299] [300] 1.46[301]
44 UGT2B28 UDP-glucuronosyltransferase 2B28 [302] 3.11[303] 3.39[304] 1.09[305] -4.39[306] [307] 1.42[308]
45 HSD17B3 Testosterone 17-beta-dehydrogenase 3 [309] -0.08[310] -0.35[311] 6.20[312] 2.41[313] -1.02[314] 1.53[315]
46 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase [316] 0.38[317] 4.20[318] 2.72[319] -3.26[320] -0.74[321] 2.29[322]
47 HSD3B1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 [323] -1.99[324] -2.88[325] 6.13[326] [327] 1.93[328] -2.29[329]
48 UGT1A7 UDP-glucuronosyltransferase 1-7 [330] 2.30[331] [332] 3.29[333] 7.18[334] 4.28[335] 3.89[336]
49 HSD3B2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 [337] -0.45[338] [339] 4.01[340] [341] 2.73[342] 1.43[343]
50 CYP11B1 Cytochrome P450 11B1, mitochondrial [344] [345] [346] [347] [348] [349] [350]
51 UGT1A10 UDP-glucuronosyltransferase 1-10 [351] [352] [353] [354] [355] [356] [357]
52 CYP11B2 Cytochrome P450 11B2, mitochondrial [358] [359] [360] [361] [362] [363] [364]
53 UGT1A8 UDP-glucuronosyltransferase 1-8 [365] [366] [367] [368] [369] [370] [371]
54 SULT2B1 Sulfotransferase family cytosolic 2B member 1 [372] [373] [374] [375] [376] [377] [378]
55 UGT2A1 UDP-glucuronosyltransferase 2A1 [379] [380] [381] [382] [383] [384] [385]
[1]
ref_hepatocyte AKR1C1
Mean 1e+03
Standard deviation 4.3e+02
Values 1.4e+03 1.3e+03 1e+03 9.2e+02 3.2e+02
[2]
HepG2 AKR1C1
Mean 329
Standard deviation 2.6e+02
Values 5.1e+02 1.5e+02
[3]
HepG2.C3A AKR1C1
Mean 233
Standard deviation 65
Values 2.8e+02 1.9e+02
[4]
HuH.7 AKR1C1
Mean 17.1
Standard deviation 16
Values 7.8 35 8.5
[5]
SNU475 AKR1C1
Mean 254
Standard deviation 82
Values 2e+02 3.1e+02
[6]
THLE AKR1C1
Mean 10.3
Standard deviation 0.06
Values 10 10
[7]
liver AKR1C1
Mean 75.6
Standard deviation 54
Values 67 63 1.5e+02 21
[8]
ref_hepatocyte HSD17B6
Mean 293
Standard deviation 4.4e+02
Values 0.55 12 4e+02 25 1e+03
[9]
HepG2 HSD17B6
Mean 0.448
Standard deviation 0.28
Values 0.65 0.25
[10]
HepG2.C3A HSD17B6
Mean 0.452
Standard deviation 0.2
Values 0.59 0.31
[11]
HuH.7 HSD17B6
Mean 0.833
Standard deviation 0.2
Values 0.65 0.8 1
[12]
SNU475 HSD17B6
Mean 8.3
Standard deviation 4.2
Values 11 5.3
[13]
THLE HSD17B6
Mean 0.727
Standard deviation 0.11
Values 0.8 0.65
[14]
liver HSD17B6
Mean 332
Standard deviation 93
Values 2.6e+02 4.3e+02 3.9e+02 2.5e+02
[15]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 0.24 11 3.2e+02 11 9.6e+02
[16]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.097 0.24
[17]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.068 0.2
[18]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.0082 0.064 0.047
[19]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[20]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[21]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 6.4e+02 4.3e+02 1.3e+03 49
[22]
ref_hepatocyte AKR1C3
Mean 242
Standard deviation 1.8e+02
Values 99 4.4e+02 4.3e+02 1.1e+02 1.2e+02
[23]
HepG2 AKR1C3
Mean 111
Standard deviation 53
Values 1.5e+02 74
[24]
HepG2.C3A AKR1C3
Mean 152
Standard deviation 34
Values 1.8e+02 1.3e+02
[25]
HuH.7 AKR1C3
Mean 1.46
Standard deviation 0.83
Values 1.1 2.4 0.84
[26]
SNU475 AKR1C3
Mean 580
Standard deviation 2.8e+02
Values 7.8e+02 3.9e+02
[27]
THLE AKR1C3
Mean 4.84
Standard deviation 0.00088
Values 4.8 4.8
[28]
liver AKR1C3
Mean 75.4
Standard deviation 53
Values 67 51 1.5e+02 32
[29]
ref_hepatocyte UGT1A6
Mean 242
Standard deviation 2.6e+02
Values 0.45 1.7e+02 4.3e+02 11 5.9e+02
[30]
HepG2 UGT1A6
Mean 1.17
Standard deviation 0.86
Values 1.8 0.56
[31]
HepG2.C3A UGT1A6
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[32]
HuH.7 UGT1A6
Mean 0.277
Standard deviation 0.33
Values 0.041 0.65 0.14
[33]
SNU475 UGT1A6
Mean 1.9
Standard deviation 0.11
Values 2 1.8
[34]
THLE UGT1A6
Mean 0.0372
Standard deviation 0.053
Values 0 0.074
[35]
liver UGT1A6
Mean 23.2
Standard deviation 17
Values 34 9 42 8.2
[36]
ref_hepatocyte UGT2B4
Mean 210
Standard deviation 2.5e+02
Values 0.056 68 4.6e+02 15 5e+02
[37]
HepG2 UGT2B4
Mean 0.666
Standard deviation 0.42
Values 0.96 0.37
[38]
HepG2.C3A UGT2B4
Mean 0.523
Standard deviation 0.23
Values 0.36 0.69
[39]
HuH.7 UGT2B4
Mean 19.1
Standard deviation 13
Values 11 34 12
[40]
SNU475 UGT2B4
Mean 0.176
Standard deviation 0.04
Values 0.2 0.15
[41]
THLE UGT2B4
Mean 0.0175
Standard deviation 0.017
Values 0.03 0.0053
[42]
liver UGT2B4
Mean 509
Standard deviation 93
Values 5.3e+02 4.5e+02 6.3e+02 4.3e+02
[43]
ref_hepatocyte AKR1C2
Mean 167
Standard deviation 1.2e+02
Values 1.2e+02 3.4e+02 2.3e+02 1.1e+02 40
[44]
HepG2 AKR1C2
Mean 199
Standard deviation 1.3e+02
Values 2.9e+02 1e+02
[45]
HepG2.C3A AKR1C2
Mean 42.9
Standard deviation 7.5
Values 48 38
[46]
HuH.7 AKR1C2
Mean 6.67
Standard deviation 6.9
Values 3 15 2.5
[47]
SNU475 AKR1C2
Mean 215
Standard deviation 34
Values 2.4e+02 1.9e+02
[48]
THLE AKR1C2
Mean 3.9
Standard deviation 0.29
Values 4.1 3.7
[49]
liver AKR1C2
Mean 106
Standard deviation 92
Values 1.1e+02 64 2.3e+02 19
[50]
ref_hepatocyte CYP3A5
Mean 139
Standard deviation 1.6e+02
Values 22 55 2e+02 35 3.9e+02
[51]
HepG2 CYP3A5
Mean 2.75
Standard deviation 2.1
Values 1.3 4.2
[52]
HepG2.C3A CYP3A5
Mean 11.4
Standard deviation 3.8
Values 14 8.7
[53]
HuH.7 CYP3A5
Mean 1.63
Standard deviation 1.6
Values 0.58 3.5 0.83
[54]
SNU475 CYP3A5
Mean 0.471
Standard deviation 0.12
Values 0.56 0.39
[55]
THLE CYP3A5
Mean 0.113
Standard deviation 0.032
Values 0.14 0.09
[56]
liver CYP3A5
Mean 424
Standard deviation 3.2e+02
Values 2.7e+02 9e+02 2.5e+02 2.8e+02
[57]
ref_hepatocyte HSD11B1
Mean 134
Standard deviation 1.2e+02
Values 0 27 2.2e+02 1.4e+02 2.9e+02
[58]
HepG2 HSD11B1
Mean 0.0208
Standard deviation 0.011
Values 0.029 0.013
[59]
HepG2.C3A HSD11B1
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[60]
HuH.7 HSD11B1
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[61]
SNU475 HSD11B1
Mean 0.372
Standard deviation 0.36
Values 0.12 0.62
[62]
THLE HSD11B1
Mean 27
Standard deviation 6.9
Values 32 22
[63]
liver HSD11B1
Mean 160
Standard deviation 98
Values 1e+02 2.4e+02 2.4e+02 51
[64]
ref_hepatocyte UGT2B7
Mean 122
Standard deviation 1.9e+02
Values 3.3 8.1 1.6e+02 5.3 4.3e+02
[65]
HepG2 UGT2B7
Mean 26.6
Standard deviation 9
Values 33 20
[66]
HepG2.C3A UGT2B7
Mean 26.2
Standard deviation 13
Values 17 35
[67]
HuH.7 UGT2B7
Mean 0.568
Standard deviation 0.44
Values 0.3 1.1 0.34
[68]
SNU475 UGT2B7
Mean 0.0439
Standard deviation 0.0096
Values 0.037 0.051
[69]
THLE UGT2B7
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[70]
liver UGT2B7
Mean 121
Standard deviation 61
Values 77 1.7e+02 1.7e+02 61
[71]
ref_hepatocyte AKR1C4
Mean 105
Standard deviation 1.4e+02
Values 0 3.6 2.3e+02 1.7 2.8e+02
[72]
HepG2 AKR1C4
Mean 0.432
Standard deviation 0.36
Values 0.69 0.18
[73]
HepG2.C3A AKR1C4
Mean 1.97
Standard deviation 0.48
Values 1.6 2.3
[74]
HuH.7 AKR1C4
Mean 1.26
Standard deviation 0.56
Values 0.75 1.9 1.2
[75]
SNU475 AKR1C4
Mean 0.118
Standard deviation 0.055
Values 0.079 0.16
[76]
THLE AKR1C4
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[77]
liver AKR1C4
Mean 80.8
Standard deviation 62
Values 66 56 1.7e+02 30
[78]
ref_hepatocyte UGT2B10
Mean 89.2
Standard deviation 1.3e+02
Values 13 1.3 1.2e+02 2.6 3.1e+02
[79]
HepG2 UGT2B10
Mean 14.5
Standard deviation 5.1
Values 11 18
[80]
HepG2.C3A UGT2B10
Mean 79.3
Standard deviation 33
Values 56 1e+02
[81]
HuH.7 UGT2B10
Mean 0.379
Standard deviation 0.38
Values 0.098 0.82 0.22
[82]
SNU475 UGT2B10
Mean 0.0293
Standard deviation 0.0087
Values 0.023 0.035
[83]
THLE UGT2B10
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[84]
liver UGT2B10
Mean 41.7
Standard deviation 22
Values 68 16 33 50
[85]
ref_hepatocyte UGT2B15
Mean 72.3
Standard deviation 99
Values 0.2 13 1.2e+02 3.3 2.3e+02
[86]
HepG2 UGT2B15
Mean 0.0487
Standard deviation 0.004
Values 0.046 0.051
[87]
HepG2.C3A UGT2B15
Mean 0.127
Standard deviation 0.013
Values 0.14 0.12
[88]
HuH.7 UGT2B15
Mean 0.2
Standard deviation 0.22
Values 0.066 0.45 0.084
[89]
SNU475 UGT2B15
Mean 0.0285
Standard deviation 0.019
Values 0.042 0.015
[90]
THLE UGT2B15
Mean 0.0219
Standard deviation 0.014
Values 0.012 0.032
[91]
liver UGT2B15
Mean 52
Standard deviation 21
Values 56 66 64 21
[92]
ref_hepatocyte UGT1A1
Mean 67.2
Standard deviation 89
Values 0.52 12 2.1e+02 15 96
[93]
HepG2 UGT1A1
Mean 1.8
Standard deviation 0.2
Values 1.9 1.7
[94]
HepG2.C3A UGT1A1
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[95]
HuH.7 UGT1A1
Mean 0.72
Standard deviation 0.5
Values 0.57 1.3 0.31
[96]
SNU475 UGT1A1
Mean 24.4
Standard deviation 21
Values 39 9.8
[97]
THLE UGT1A1
Mean 0.0266
Standard deviation 0.038
Values 0 0.053
[98]
liver UGT1A1
Mean 92.4
Standard deviation 46
Values 83 1.1e+02 1.4e+02 34
[99]
ref_hepatocyte UGT1A4
Mean 53.1
Standard deviation 73
Values 0 4.2 99 2.5 1.6e+02
[100]
HepG2 UGT1A4
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[101]
HepG2.C3A UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 UGT1A4
Mean 0.00954
Standard deviation 0.0096
Values 0 0.019 0.0094
[103]
SNU475 UGT1A4
Mean 0.031
Standard deviation 0.015
Values 0.042 0.02
[104]
THLE UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[105]
liver UGT1A4
Mean 83.1
Standard deviation 65
Values 95 36 1.7e+02 32
[106]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 77 43 17 0.06 82
[107]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 6.2 2.6
[108]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.4 1.2
[109]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 14 17 17
[110]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 0.49 3.1
[111]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[112]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 0.47 1.2 0.92 1.8
[113]
ref_hepatocyte COMT
Mean 41.6
Standard deviation 29
Values 24 25 61 14 83
[114]
HepG2 COMT
Mean 59.3
Standard deviation 6.8
Values 64 55
[115]
HepG2.C3A COMT
Mean 80
Standard deviation 0.37
Values 80 80
[116]
HuH.7 COMT
Mean 17.1
Standard deviation 2.6
Values 14 18 19
[117]
SNU475 COMT
Mean 22.9
Standard deviation 4.5
Values 26 20
[118]
THLE COMT
Mean 26.6
Standard deviation 0.81
Values 26 27
[119]
liver COMT
Mean 76.3
Standard deviation 82
Values 20 1.9e+02 71 20
[120]
ref_hepatocyte HSD17B2
Mean 38.5
Standard deviation 40
Values 8.2 9.4 81 11 83
[121]
HepG2 HSD17B2
Mean 14.3
Standard deviation 1.8
Values 16 13
[122]
HepG2.C3A HSD17B2
Mean 34.6
Standard deviation 18
Values 47 22
[123]
HuH.7 HSD17B2
Mean 24.8
Standard deviation 4.5
Values 23 30 22
[124]
SNU475 HSD17B2
Mean 0.0863
Standard deviation 0.029
Values 0.11 0.066
[125]
THLE HSD17B2
Mean 0.334
Standard deviation 0.16
Values 0.45 0.22
[126]
liver HSD17B2
Mean 36.9
Standard deviation 25
Values 24 51 64 8.9
[127]
ref_hepatocyte CYP3A7
Mean 29.1
Standard deviation 41
Values 8.7 0.12 1e+02 5 32
[128]
HepG2 CYP3A7
Mean 0.531
Standard deviation 0.38
Values 0.26 0.8
[129]
HepG2.C3A CYP3A7
Mean 2.26
Standard deviation 0.013
Values 2.3 2.3
[130]
HuH.7 CYP3A7
Mean 0.0822
Standard deviation 0.074
Values 0.033 0.17 0.047
[131]
SNU475 CYP3A7
Mean 0
Standard deviation 0
Values 0 0
[132]
THLE CYP3A7
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[133]
liver CYP3A7
Mean 13
Standard deviation 12
Values 5.2 30 11 5.1
[134]
ref_hepatocyte AKR1D1
Mean 25.3
Standard deviation 42
Values 4.5 0.35 23 0.37 99
[135]
HepG2 AKR1D1
Mean 6.61
Standard deviation 3
Values 4.5 8.7
[136]
HepG2.C3A AKR1D1
Mean 15.2
Standard deviation 0.35
Values 15 15
[137]
HuH.7 AKR1D1
Mean 2.24
Standard deviation 3.1
Values 0.38 5.8 0.5
[138]
SNU475 AKR1D1
Mean 0.042
Standard deviation 0.027
Values 0.023 0.061
[139]
THLE AKR1D1
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[140]
liver AKR1D1
Mean 29.7
Standard deviation 5.8
Values 35 23 26 34
[141]
ref_hepatocyte HSD17B8
Mean 20.7
Standard deviation 21
Values 2.8 7.2 35 8.9 50
[142]
HepG2 HSD17B8
Mean 4.91
Standard deviation 2.1
Values 6.4 3.4
[143]
HepG2.C3A HSD17B8
Mean 7.45
Standard deviation 2.6
Values 9.3 5.6
[144]
HuH.7 HSD17B8
Mean 8.11
Standard deviation 2.7
Values 7.9 5.5 11
[145]
SNU475 HSD17B8
Mean 0.537
Standard deviation 0.11
Values 0.61 0.46
[146]
THLE HSD17B8
Mean 1.24
Standard deviation 0.29
Values 1.4 1
[147]
liver HSD17B8
Mean 12
Standard deviation 9.2
Values 4.1 22 18 4.3
[148]
ref_hepatocyte HSD17B12
Mean 20.5
Standard deviation 14
Values 5.1 15 28 13 42
[149]
HepG2 HSD17B12
Mean 19.8
Standard deviation 1.3
Values 19 21
[150]
HepG2.C3A HSD17B12
Mean 41.8
Standard deviation 12
Values 50 34
[151]
HuH.7 HSD17B12
Mean 59.9
Standard deviation 5.1
Values 57 66 57
[152]
SNU475 HSD17B12
Mean 8.53
Standard deviation 0.57
Values 8.1 8.9
[153]
THLE HSD17B12
Mean 20.1
Standard deviation 2.8
Values 18 22
[154]
liver HSD17B12
Mean 58.4
Standard deviation 21
Values 62 56 83 32
[155]
ref_hepatocyte UGT1A9
Mean 15.2
Standard deviation 13
Values 0 21 26 2.6 27
[156]
HepG2 UGT1A9
Mean 0.16
Standard deviation 0.057
Values 0.2 0.12
[157]
HepG2.C3A UGT1A9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[158]
HuH.7 UGT1A9
Mean 0.0656
Standard deviation 0.056
Values 0.066 0.12 0.0094
[159]
SNU475 UGT1A9
Mean 0.273
Standard deviation 0.34
Values 0.51 0.03
[160]
THLE UGT1A9
Mean 0.00798
Standard deviation 0.011
Values 0 0.016
[161]
liver UGT1A9
Mean 13.9
Standard deviation 9.6
Values 22 8.7 22 3
[162]
ref_hepatocyte HSD17B7
Mean 14.9
Standard deviation 12
Values 14 8.9 35 4 12
[163]
HepG2 HSD17B7
Mean 3.52
Standard deviation 0.97
Values 2.8 4.2
[164]
HepG2.C3A HSD17B7
Mean 11.3
Standard deviation 3.5
Values 14 8.9
[165]
HuH.7 HSD17B7
Mean 11.1
Standard deviation 1.6
Values 9.5 13 11
[166]
SNU475 HSD17B7
Mean 2.62
Standard deviation 1.2
Values 3.5 1.7
[167]
THLE HSD17B7
Mean 2.28
Standard deviation 0.47
Values 1.9 2.6
[168]
liver HSD17B7
Mean 12.3
Standard deviation 4.1
Values 6.2 15 13 15
[169]
ref_hepatocyte UGT2B17
Mean 10.8
Standard deviation 16
Values 0 1.3 15 1.3 37
[170]
HepG2 UGT2B17
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[171]
HepG2.C3A UGT2B17
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[172]
HuH.7 UGT2B17
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[173]
SNU475 UGT2B17
Mean 0
Standard deviation 0
Values 0 0
[174]
THLE UGT2B17
Mean 0
Standard deviation 0
Values 0 0
[175]
liver UGT2B17
Mean 6
Standard deviation 4.8
Values 8.6 3.7 11 0.5
[176]
ref_hepatocyte SRD5A1
Mean 9.94
Standard deviation 8.7
Values 6.1 6.5 11 1.9 24
[177]
HepG2 SRD5A1
Mean 5.45
Standard deviation 0.84
Values 4.9 6
[178]
HepG2.C3A SRD5A1
Mean 5.22
Standard deviation 0.13
Values 5.3 5.1
[179]
HuH.7 SRD5A1
Mean 10.1
Standard deviation 0.77
Values 10 9.3 11
[180]
SNU475 SRD5A1
Mean 8.73
Standard deviation 0.84
Values 9.3 8.1
[181]
THLE SRD5A1
Mean 13.5
Standard deviation 3.6
Values 16 11
[182]
liver SRD5A1
Mean 32.2
Standard deviation 11
Values 26 48 24 31
[183]
ref_hepatocyte UGT2A3
Mean 7.91
Standard deviation 6.4
Values 18 5.7 9.3 0.33 6.3
[184]
HepG2 UGT2A3
Mean 42.4
Standard deviation 14
Values 33 52
[185]
HepG2.C3A UGT2A3
Mean 137
Standard deviation 28
Values 1.2e+02 1.6e+02
[186]
HuH.7 UGT2A3
Mean 0.775
Standard deviation 0.72
Values 0.33 1.6 0.39
[187]
SNU475 UGT2A3
Mean 0.11
Standard deviation 0.13
Values 0.2 0.02
[188]
THLE UGT2A3
Mean 0.0172
Standard deviation 0.0092
Values 0.024 0.011
[189]
liver UGT2A3
Mean 31.9
Standard deviation 15
Values 24 55 25 24
[190]
ref_hepatocyte SRD5A2
Mean 6.56
Standard deviation 6.6
Values 0.19 8.5 5.8 1.5 17
[191]
HepG2 SRD5A2
Mean 0.0351
Standard deviation 0.031
Values 0.057 0.013
[192]
HepG2.C3A SRD5A2
Mean 0.055
Standard deviation 0.032
Values 0.078 0.032
[193]
HuH.7 SRD5A2
Mean 0.0502
Standard deviation 0.057
Values 0.016 0.12 0.019
[194]
SNU475 SRD5A2
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[195]
THLE SRD5A2
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[196]
liver SRD5A2
Mean 7.73
Standard deviation 6.8
Values 3.3 5.4 4.4 18
[197]
ref_hepatocyte CYP21A2
Mean 5.14
Standard deviation 5.5
Values 0.5 0.83 13 2.4 9.3
[198]
HepG2 CYP21A2
Mean 0.195
Standard deviation 0.0088
Values 0.19 0.2
[199]
HepG2.C3A CYP21A2
Mean 0.66
Standard deviation 0.51
Values 1 0.3
[200]
HuH.7 CYP21A2
Mean 0.0306
Standard deviation 0.027
Values 0 0.045 0.047
[201]
SNU475 CYP21A2
Mean 0.502
Standard deviation 0.11
Values 0.43 0.58
[202]
THLE CYP21A2
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[203]
liver CYP21A2
Mean 6.05
Standard deviation 3.4
Values 6 2 10 5.9
[204]
ref_hepatocyte UGT1A3
Mean 4.24
Standard deviation 4.8
Values 0 2.3 7.9 0.37 11
[205]
HepG2 UGT1A3
Mean 1.2
Standard deviation 0.2
Values 1.3 1.1
[206]
HepG2.C3A UGT1A3
Mean 0
Standard deviation 0
Values 0 0
[207]
HuH.7 UGT1A3
Mean 0.0101
Standard deviation 0.0024
Values 0.0082 0.013 0.0094
[208]
SNU475 UGT1A3
Mean 0.0911
Standard deviation 0.029
Values 0.11 0.071
[209]
THLE UGT1A3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[210]
liver UGT1A3
Mean 14.2
Standard deviation 12
Values 21 2.5 28 5.8
[211]
ref_hepatocyte CYP7A1
Mean 4.03
Standard deviation 5.2
Values 9.8 0 0.69 0 9.7
[212]
HepG2 CYP7A1
Mean 0.438
Standard deviation 0.47
Values 0.11 0.77
[213]
HepG2.C3A CYP7A1
Mean 0.0774
Standard deviation 0.027
Values 0.058 0.097
[214]
HuH.7 CYP7A1
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[215]
SNU475 CYP7A1
Mean 0.00739
Standard deviation 0.0039
Values 0.0046 0.01
[216]
THLE CYP7A1
Mean 0
Standard deviation 0
Values 0 0
[217]
liver CYP7A1
Mean 0.737
Standard deviation 0.45
Values 0.94 1.1 0.82 0.079
[218]
ref_hepatocyte SRD5A3
Mean 2.79
Standard deviation 1.2
Values 3.1 2.9 2.1 1.4 4.5
[219]
HepG2 SRD5A3
Mean 9.75
Standard deviation 3.5
Values 7.3 12
[220]
HepG2.C3A SRD5A3
Mean 6.61
Standard deviation 1.4
Values 5.6 7.6
[221]
HuH.7 SRD5A3
Mean 6.78
Standard deviation 0.38
Values 7.1 6.8 6.4
[222]
SNU475 SRD5A3
Mean 5.03
Standard deviation 0.79
Values 5.6 4.5
[223]
THLE SRD5A3
Mean 6.51
Standard deviation 1.2
Values 5.7 7.4
[224]
liver SRD5A3
Mean 5.36
Standard deviation 1.4
Values 3.5 5.9 6.9 5.1
[225]
ref_hepatocyte SULT1E1
Mean 2.69
Standard deviation 3.5
Values 0.8 0.67 3.3 0.15 8.5
[226]
HepG2 SULT1E1
Mean 0.821
Standard deviation 0.16
Values 0.71 0.93
[227]
HepG2.C3A SULT1E1
Mean 4.62
Standard deviation 1.2
Values 3.8 5.5
[228]
HuH.7 SULT1E1
Mean 6.19
Standard deviation 1.8
Values 4.4 7.9 6.3
[229]
SNU475 SULT1E1
Mean 0.0169
Standard deviation 0.0024
Values 0.019 0.015
[230]
THLE SULT1E1
Mean 7.92
Standard deviation 1.1
Values 7.1 8.7
[231]
liver SULT1E1
Mean 8.11
Standard deviation 8.7
Values 2.4 21 4.2 4.8
[232]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.024 8 2.7 0.92 1.4
[233]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.057 0.03
[234]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.029 0.086
[235]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.87 1 0.95
[236]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 16 11
[237]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[238]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 7.4 6.9 9.5 6.2
[239]
ref_hepatocyte HSD17B1
Mean 1.84
Standard deviation 1.8
Values 0 0 3.6 3.8 1.8
[240]
HepG2 HSD17B1
Mean 7.09
Standard deviation 0.31
Values 7.3 6.9
[241]
HepG2.C3A HSD17B1
Mean 9.86
Standard deviation 0.69
Values 10 9.4
[242]
HuH.7 HSD17B1
Mean 6.23
Standard deviation 0.45
Values 6 5.9 6.7
[243]
SNU475 HSD17B1
Mean 3.28
Standard deviation 0.071
Values 3.3 3.2
[244]
THLE HSD17B1
Mean 3.07
Standard deviation 0.04
Values 3.1 3
[245]
liver HSD17B1
Mean 1.94
Standard deviation 0.82
Values 0.98 2.9 2.1 1.7
[246]
ref_hepatocyte CYP3A43
Mean 1.46
Standard deviation 2.7
Values 0.059 0 1.1 0 6.1
[247]
HepG2 CYP3A43
Mean 0.112
Standard deviation 0.061
Values 0.069 0.15
[248]
HepG2.C3A CYP3A43
Mean 0.735
Standard deviation 0.42
Values 1 0.44
[249]
HuH.7 CYP3A43
Mean 0.622
Standard deviation 0.91
Values 0.057 1.7 0.14
[250]
SNU475 CYP3A43
Mean 0
Standard deviation 0
Values 0 0
[251]
THLE CYP3A43
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[252]
liver CYP3A43
Mean 5.41
Standard deviation 4.2
Values 2.9 12 3.4 3.6
[253]
ref_hepatocyte CYP7B1
Mean 1.44
Standard deviation 1
Values 0 2.2 1.2 1.1 2.7
[254]
HepG2 CYP7B1
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[255]
HepG2.C3A CYP7B1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[256]
HuH.7 CYP7B1
Mean 0
Standard deviation 0
Values 0 0 0
[257]
SNU475 CYP7B1
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[258]
THLE CYP7B1
Mean 0.0751
Standard deviation 0.014
Values 0.065 0.085
[259]
liver CYP7B1
Mean 9.87
Standard deviation 5.4
Values 17 6.3 4.8 12
[260]
ref_hepatocyte STS
Mean 1.2
Standard deviation 0.64
Values 0.53 0.62 1.9 1.2 1.8
[261]
HepG2 STS
Mean 2.95
Standard deviation 1.7
Values 1.7 4.2
[262]
HepG2.C3A STS
Mean 1.81
Standard deviation 1.1
Values 1 2.6
[263]
HuH.7 STS
Mean 3.93
Standard deviation 0.79
Values 4.8 3.3 3.7
[264]
SNU475 STS
Mean 1.49
Standard deviation 0.27
Values 1.3 1.7
[265]
THLE STS
Mean 7.51
Standard deviation 0.018
Values 7.5 7.5
[266]
liver STS
Mean 7.39
Standard deviation 1.4
Values 6.4 8.2 6 8.9
[267]
ref_hepatocyte CYP19A1
Mean 1.13
Standard deviation 2.3
Values 5.3 0.08 0 0.28 0
[268]
HepG2 CYP19A1
Mean 9.51
Standard deviation 0.87
Values 8.9 10
[269]
HepG2.C3A CYP19A1
Mean 17.1
Standard deviation 5.6
Values 21 13
[270]
HuH.7 CYP19A1
Mean 0.188
Standard deviation 0.27
Values 0.016 0.5 0.047
[271]
SNU475 CYP19A1
Mean 0.66
Standard deviation 0.58
Values 0.25 1.1
[272]
THLE CYP19A1
Mean 0.135
Standard deviation 0.018
Values 0.15 0.12
[273]
liver CYP19A1
Mean 0.0199
Standard deviation 0.04
Values 0 0 0 0.079
[274]
ref_hepatocyte CYP11A1
Mean 0.602
Standard deviation 0.44
Values 0.18 0.47 0.59 0.44 1.3
[275]
HepG2 CYP11A1
Mean 0.843
Standard deviation 0.49
Values 1.2 0.49
[276]
HepG2.C3A CYP11A1
Mean 0.131
Standard deviation 0.049
Values 0.17 0.097
[277]
HuH.7 CYP11A1
Mean 0
Standard deviation 0
Values 0 0 0
[278]
SNU475 CYP11A1
Mean 0.115
Standard deviation 0.045
Values 0.083 0.15
[279]
THLE CYP11A1
Mean 2.14
Standard deviation 0.87
Values 2.8 1.5
[280]
liver CYP11A1
Mean 1.18
Standard deviation 0.65
Values 0.57 1.4 2 0.75
[281]
ref_hepatocyte HSD11B2
Mean 0.44
Standard deviation 0.31
Values 0.31 0 0.6 0.47 0.81
[282]
HepG2 HSD11B2
Mean 4.48
Standard deviation 0.0009
Values 4.5 4.5
[283]
HepG2.C3A HSD11B2
Mean 4.1
Standard deviation 0.84
Values 4.7 3.5
[284]
HuH.7 HSD11B2
Mean 2.2
Standard deviation 1.5
Values 2.8 0.48 3.3
[285]
SNU475 HSD11B2
Mean 0.167
Standard deviation 0.079
Values 0.22 0.11
[286]
THLE HSD11B2
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[287]
liver HSD11B2
Mean 0.978
Standard deviation 0.63
Values 0.3 1.6 0.59 1.5
[288]
ref_hepatocyte UGT1A5
Mean 0.393
Standard deviation 0.32
Values 0 0.38 0.82 0.19 0.58
[289]
HepG2 UGT1A5
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[290]
HepG2.C3A UGT1A5
Mean 0
Standard deviation 0
Values 0 0
[291]
HuH.7 UGT1A5
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[292]
SNU475 UGT1A5
Mean 0.0747
Standard deviation 0.012
Values 0.083 0.066
[293]
THLE UGT1A5
Mean 0
Standard deviation 0
Values 0 0
[294]
liver UGT1A5
Mean 1.38
Standard deviation 1.4
Values 3.4 0.31 0.98 0.85
[295]
ref_hepatocyte UGT2B11
Mean 0.391
Standard deviation 0.65
Values 0 0 1.5 0 0.46
[296]
HepG2 UGT2B11
Mean 1
Standard deviation 0.2
Values 0.86 1.1
[297]
HepG2.C3A UGT2B11
Mean 0.348
Standard deviation 0.19
Values 0.21 0.48
[298]
HuH.7 UGT2B11
Mean 0.795
Standard deviation 0.79
Values 0.31 1.7 0.37
[299]
SNU475 UGT2B11
Mean 0.00928
Standard deviation 0.013
Values 0.019 0
[300]
THLE UGT2B11
Mean 0
Standard deviation 0
Values 0 0
[301]
liver UGT2B11
Mean 0.98
Standard deviation 0.68
Values 0.59 2 0.49 0.87
[302]
ref_hepatocyte UGT2B28
Mean 0.294
Standard deviation 0.52
Values 0 0 0.28 0 1.2
[303]
HepG2 UGT2B28
Mean 0.642
Standard deviation 0.23
Values 0.81 0.48
[304]
HepG2.C3A UGT2B28
Mean 0.816
Standard deviation 0.45
Values 0.5 1.1
[305]
HuH.7 UGT2B28
Mean 0.0413
Standard deviation 0.043
Values 0.025 0.09 0.0094
[306]
SNU475 UGT2B28
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[307]
THLE UGT2B28
Mean 0
Standard deviation 0
Values 0 0
[308]
liver UGT2B28
Mean 0.714
Standard deviation 0.87
Values 1.1 0 1.8 0.013
[309]
ref_hepatocyte HSD17B3
Mean 0.262
Standard deviation 0.31
Values 0 0.1 0.63 0 0.58
[310]
HepG2 HSD17B3
Mean 0.063
Standard deviation 0.032
Values 0.04 0.086
[311]
HepG2.C3A HSD17B3
Mean 0.0545
Standard deviation 0.047
Values 0.087 0.021
[312]
HuH.7 HSD17B3
Mean 1.27
Standard deviation 0.54
Values 0.65 1.5 1.6
[313]
SNU475 HSD17B3
Mean 0.46
Standard deviation 0.0054
Values 0.46 0.46
[314]
THLE HSD17B3
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[315]
liver HSD17B3
Mean 0.686
Standard deviation 0.23
Values 0.54 0.89 0.44 0.87
[316]
ref_hepatocyte CYP17A1
Mean 0.208
Standard deviation 0.25
Values 0 0 0.6 0.31 0.13
[317]
HepG2 CYP17A1
Mean 0.0687
Standard deviation 0.024
Values 0.086 0.051
[318]
HepG2.C3A CYP17A1
Mean 1.01
Standard deviation 0.19
Values 1.1 0.88
[319]
HuH.7 CYP17A1
Mean 0.0898
Standard deviation 0.047
Values 0.041 0.13 0.094
[320]
SNU475 CYP17A1
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[321]
THLE CYP17A1
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[322]
liver CYP17A1
Mean 0.926
Standard deviation 1.4
Values 0.057 2.9 0.21 0.5
[323]
ref_hepatocyte HSD3B1
Mean 0.134
Standard deviation 0.3
Values 0 0 0.67 0 0
[324]
HepG2 HSD3B1
Mean 0.0086
Standard deviation 0.012
Values 0.017 0
[325]
HepG2.C3A HSD3B1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[326]
HuH.7 HSD3B1
Mean 0.62
Standard deviation 0.19
Values 0.68 0.41 0.77
[327]
SNU475 HSD3B1
Mean 0
Standard deviation 0
Values 0 0
[328]
THLE HSD3B1
Mean 0.034
Standard deviation 0.01
Values 0.041 0.027
[329]
liver HSD3B1
Mean 0.025
Standard deviation 0.029
Values 0 0.047 0 0.053
[330]
ref_hepatocyte UGT1A7
Mean 0.0431
Standard deviation 0.096
Values 0 0 0.22 0 0
[331]
HepG2 UGT1A7
Mean 0.0537
Standard deviation 0.021
Values 0.069 0.039
[332]
HepG2.C3A UGT1A7
Mean 0
Standard deviation 0
Values 0 0
[333]
HuH.7 UGT1A7
Mean 0.0277
Standard deviation 0.011
Values 0.016 0.039 0.028
[334]
SNU475 UGT1A7
Mean 2.06
Standard deviation 1.2
Values 1.2 2.9
[335]
THLE UGT1A7
Mean 0.0556
Standard deviation 0.012
Values 0.047 0.064
[336]
liver UGT1A7
Mean 0.582
Standard deviation 0.83
Values 1.8 0.094 0.1 0.32
[337]
ref_hepatocyte HSD3B2
Mean 0.031
Standard deviation 0.065
Values 0 0 0.0086 0 0.15
[338]
HepG2 HSD3B2
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[339]
HepG2.C3A HSD3B2
Mean 0
Standard deviation 0
Values 0 0
[340]
HuH.7 HSD3B2
Mean 0.0327
Standard deviation 0.028
Values 0.025 0.064 0.0094
[341]
SNU475 HSD3B2
Mean 0
Standard deviation 0
Values 0 0
[342]
THLE HSD3B2
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[343]
liver HSD3B2
Mean 0.0756
Standard deviation 0.044
Values 0.057 0.14 0.051 0.053
[344]
ref_hepatocyte CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[345]
HepG2 CYP11B1
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[346]
HepG2.C3A CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[347]
HuH.7 CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0
[348]
SNU475 CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[349]
THLE CYP11B1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[350]
liver CYP11B1
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[351]
ref_hepatocyte UGT1A10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[352]
HepG2 UGT1A10
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[353]
HepG2.C3A UGT1A10
Mean 0
Standard deviation 0
Values 0 0
[354]
HuH.7 UGT1A10
Mean 0.115
Standard deviation 0.078
Values 0.066 0.21 0.075
[355]
SNU475 UGT1A10
Mean 0.012
Standard deviation 0.0027
Values 0.014 0.01
[356]
THLE UGT1A10
Mean 0
Standard deviation 0
Values 0 0
[357]
liver UGT1A10
Mean 0.0104
Standard deviation 0.014
Values 0.029 0 0 0.013
[358]
ref_hepatocyte CYP11B2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[359]
HepG2 CYP11B2
Missing
[360]
HepG2.C3A CYP11B2
Missing
[361]
HuH.7 CYP11B2
Missing
[362]
SNU475 CYP11B2
Missing
[363]
THLE CYP11B2
Missing
[364]
liver CYP11B2
Missing
[365]
ref_hepatocyte UGT1A8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[366]
HepG2 UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[367]
HepG2.C3A UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[368]
HuH.7 UGT1A8
Mean 0.0407
Standard deviation 0.027
Values 0.033 0.071 0.019
[369]
SNU475 UGT1A8
Mean 0.152
Standard deviation 0.028
Values 0.17 0.13
[370]
THLE UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[371]
liver UGT1A8
Mean 0.0104
Standard deviation 0.014
Values 0.029 0 0 0.013
[372]
ref_hepatocyte SULT2B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[373]
HepG2 SULT2B1
Mean 2.26
Standard deviation 1.3
Values 3.2 1.3
[374]
HepG2.C3A SULT2B1
Mean 0.0468
Standard deviation 0.025
Values 0.029 0.064
[375]
HuH.7 SULT2B1
Mean 0.407
Standard deviation 0.08
Values 0.34 0.38 0.5
[376]
SNU475 SULT2B1
Mean 0.303
Standard deviation 0.21
Values 0.45 0.15
[377]
THLE SULT2B1
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[378]
liver SULT2B1
Mean 0.0309
Standard deviation 0.027
Values 0.014 0.071 0.026 0.013
[379]
ref_hepatocyte UGT2A1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[380]
HepG2 UGT2A1
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[381]
HepG2.C3A UGT2A1
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[382]
HuH.7 UGT2A1
Mean 0
Standard deviation 0
Values 0 0 0
[383]
SNU475 UGT2A1
Mean 0.015
Standard deviation 0.015
Values 0.0046 0.025
[384]
THLE UGT2A1
Mean 0
Standard deviation 0
Values 0 0
[385]
liver UGT2A1
Mean 0.00999
Standard deviation 0.012
Values 0.014 0 0.026 0