KEGG_SELENOAMINO_ACID_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MAT1A S-adenosylmethionine synthase isoform type-1 [1] -2.84[2] -1.39[3] -3.47[4] -9.08[5] -11.56[6] 0.54[7]
2 SEPHS2 Selenide, water dikinase 2 [8] -0.42[9] -0.53[10] -0.31[11] -2.07[12] -2.38[13] -1.40[14]
3 AHCY Adenosylhomocysteinase [15] 1.66[16] 1.66[17] 1.73[18] 0.58[19] 0.19[20] -1.41[21]
4 CBS Cystathionine beta-synthase [22] -0.81[23] -1.03[24] 0.38[25] -2.27[26] -0.71[27] 0.56[28]
5 MAT2A S-adenosylmethionine synthase isoform type-2 [29] 1.19[30] 1.09[31] 0.73[32] 2.18[33] 2.45[34] 0.48[35]
6 PAPSS2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [36] -4.97[37] -7.32[38] -0.23[39] 1.22[40] 1.69[41] 1.11[42]
7 AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 [43] 0.91[44] 0.58[45] 0.99[46] 2.37[47] 2.28[48] -0.10[49]
8 CTH Cystathionine gamma-lyase [50] -1.75[51] -2.93[52] -1.19[53] -3.24[54] -2.69[55] -0.46[56]
9 GGT1 Glutathione hydrolase 1 proenzyme [57] 0.00[58] -0.70[59] -1.08[60] -0.83[61] -5.33[62] 0.32[63]
10 MAT2B Methionine adenosyltransferase 2 subunit beta [64] 0.59[65] 0.24[66] 0.28[67] 1.82[68] 1.75[69] -0.37[70]
11 PAPSS1 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [71] 1.40[72] 1.43[73] 0.55[74] 1.55[75] 1.68[76] -1.89[77]
12 SEPHS1 Selenide, water dikinase 1 [78] 1.38[79] 1.34[80] 1.06[81] 2.61[82] 1.87[83] -0.49[84]
13 TRMT11 tRNA (guanine(10)-N2)-methyltransferase homolog [85] -0.68[86] 0.31[87] -0.98[88] -0.28[89] 0.14[90] -0.06[91]
14 METTL2B Methyltransferase-like protein 2B [92] -0.37[93] -1.08[94] -0.82[95] 0.19[96] 0.14[97] -1.58[98]
15 SCLY Selenocysteine lyase [99] -4.06[100] -5.29[101] -4.03[102] -4.86[103] -4.27[104] -5.84[105]
16 LCMT1 Leucine carboxyl methyltransferase 1 [106] 1.42[107] 1.01[108] 0.65[109] 0.24[110] 0.88[111] -2.25[112]
17 METTL6 Methyltransferase-like protein 6 [113] 1.04[114] 0.14[115] 0.66[116] 1.33[117] 1.85[118] -1.48[119]
18 MARS2 Methionine--tRNA ligase, mitochondrial [120] 1.54[121] 0.74[122] 0.61[123] 0.45[124] 1.16[125] 0.51[126]
19 LCMT2 tRNA wybutosine-synthesizing protein 4 [127] 0.75[128] -0.07[129] -0.35[130] 1.49[131] 1.79[132] -0.01[133]
20 HEMK1 HemK methyltransferase family member 1 [134] 1.06[135] 1.81[136] 1.82[137] 2.03[138] 2.27[139] 1.47[140]
21 GGT7 Glutathione hydrolase 7 [141] 2.46[142] 2.35[143] 1.75[144] 3.32[145] 2.48[146] -0.04[147]
22 AHCYL2 Adenosylhomocysteinase 3 [148] 2.51[149] 2.22[150] 2.14[151] 3.58[152] 3.64[153] 1.53[154]
23 GGT6 Glutathione hydrolase 6 [155] 1.00[156] 1.11[157] -0.79[158] 0.37[159] -0.31[160] -0.40[161]
24 GGT5 Glutathione hydrolase 5 proenzyme [162] 5.25[163] 2.20[164] -2.84[165] 5.26[166] 5.44[167] 5.24[168]
25 BUD23 Probable 18S rRNA (guanine-N(7))-methyltransferase [169] [170] [171] [172] [173] [174] [175]
26 MARS1 [176] [177] [178] [179] [180] [181] [182]
[1]
ref_hepatocyte MAT1A
Mean 212
Standard deviation 2.8e+02
Values 46 12 3.6e+02 7.2 6.3e+02
[2]
HepG2 MAT1A
Mean 41.1
Standard deviation 3.9
Values 38 44
[3]
HepG2.C3A MAT1A
Mean 135
Standard deviation 10
Values 1.4e+02 1.3e+02
[4]
HuH.7 MAT1A
Mean 34.1
Standard deviation 22
Values 20 60 22
[5]
SNU475 MAT1A
Mean 0.281
Standard deviation 0.061
Values 0.32 0.24
[6]
THLE MAT1A
Mean 0.055
Standard deviation 0.048
Values 0.089 0.021
[7]
liver MAT1A
Mean 578
Standard deviation 1.7e+02
Values 6.1e+02 4.8e+02 8.1e+02 4.1e+02
[8]
ref_hepatocyte SEPHS2
Mean 140
Standard deviation 64
Values 1.9e+02 94 1.7e+02 52 2e+02
[9]
HepG2 SEPHS2
Mean 145
Standard deviation 13
Values 1.4e+02 1.5e+02
[10]
HepG2.C3A SEPHS2
Mean 161
Standard deviation 13
Values 1.7e+02 1.5e+02
[11]
HuH.7 SEPHS2
Mean 201
Standard deviation 34
Values 1.7e+02 2.3e+02 2e+02
[12]
SNU475 SEPHS2
Mean 23.9
Standard deviation 2.2
Values 26 22
[13]
THLE SEPHS2
Mean 21
Standard deviation 3.8
Values 18 24
[14]
liver SEPHS2
Mean 99.5
Standard deviation 53
Values 59 1.7e+02 1.1e+02 57
[15]
ref_hepatocyte AHCY
Mean 72
Standard deviation 24
Values 1e+02 71 80 38 67
[16]
HepG2 AHCY
Mean 316
Standard deviation 75
Values 3.7e+02 2.6e+02
[17]
HepG2.C3A AHCY
Mean 377
Standard deviation 69
Values 4.3e+02 3.3e+02
[18]
HuH.7 AHCY
Mean 425
Standard deviation 39
Values 4.7e+02 4e+02 4e+02
[19]
SNU475 AHCY
Mean 77.3
Standard deviation 9.8
Values 84 70
[20]
THLE AHCY
Mean 64.2
Standard deviation 8.6
Values 58 70
[21]
liver AHCY
Mean 50.8
Standard deviation 11
Values 45 55 64 40
[22]
ref_hepatocyte CBS
Mean 54.1
Standard deviation 52
Values 7.7 22 96 21 1.2e+02
[23]
HepG2 CBS
Mean 42.6
Standard deviation 25
Values 60 25
[24]
HepG2.C3A CBS
Mean 44
Standard deviation 22
Values 60 28
[25]
HuH.7 CBS
Mean 125
Standard deviation 32
Values 1.4e+02 89 1.5e+02
[26]
SNU475 CBS
Mean 8.06
Standard deviation 1.8
Values 9.3 6.8
[27]
THLE CBS
Mean 25.8
Standard deviation 4.2
Values 29 23
[28]
liver CBS
Mean 150
Standard deviation 40
Values 1.1e+02 2e+02 1.6e+02 1.3e+02
[29]
ref_hepatocyte MAT2A
Mean 23.3
Standard deviation 13
Values 15 27 44 14 16
[30]
HepG2 MAT2A
Mean 73.6
Standard deviation 11
Values 66 81
[31]
HepG2.C3A MAT2A
Mean 82.6
Standard deviation 22
Values 67 98
[32]
HuH.7 MAT2A
Mean 68.8
Standard deviation 31
Values 79 34 93
[33]
SNU475 MAT2A
Mean 75.8
Standard deviation 6
Values 72 80
[34]
THLE MAT2A
Mean 99.7
Standard deviation 1.6
Values 1e+02 99
[35]
liver MAT2A
Mean 61
Standard deviation 25
Values 46 78 86 34
[36]
ref_hepatocyte PAPSS2
Mean 21.5
Standard deviation 20
Values 0.061 46 19 5.9 36
[37]
HepG2 PAPSS2
Mean 0.947
Standard deviation 0.24
Values 0.78 1.1
[38]
HepG2.C3A PAPSS2
Mean 0.223
Standard deviation 0.11
Values 0.15 0.3
[39]
HuH.7 PAPSS2
Mean 32.5
Standard deviation 12
Values 28 46 24
[40]
SNU475 PAPSS2
Mean 36
Standard deviation 1.8
Values 35 37
[41]
THLE PAPSS2
Mean 54.1
Standard deviation 10
Values 47 61
[42]
liver PAPSS2
Mean 87.1
Standard deviation 22
Values 68 1e+02 1.1e+02 69
[43]
ref_hepatocyte AHCYL1
Mean 21.3
Standard deviation 7.5
Values 25 31 20 12 18
[44]
HepG2 AHCYL1
Mean 55.4
Standard deviation 1.1
Values 56 55
[45]
HepG2.C3A AHCYL1
Mean 52.7
Standard deviation 1.2
Values 54 52
[46]
HuH.7 AHCYL1
Mean 75.1
Standard deviation 17
Values 90 56 79
[47]
SNU475 AHCYL1
Mean 78.9
Standard deviation 16
Values 90 67
[48]
THLE AHCYL1
Mean 80.7
Standard deviation 6.3
Values 76 85
[49]
liver AHCYL1
Mean 37.2
Standard deviation 6
Values 41 43 35 30
[50]
ref_hepatocyte CTH
Mean 20.3
Standard deviation 26
Values 1.2 1.6 24 9.9 64
[51]
HepG2 CTH
Mean 8.35
Standard deviation 5.8
Values 12 4.2
[52]
HepG2.C3A CTH
Mean 4.42
Standard deviation 2.6
Values 6.3 2.6
[53]
HuH.7 CTH
Mean 15.7
Standard deviation 1.2
Values 16 17 14
[54]
SNU475 CTH
Mean 1.54
Standard deviation 0.042
Values 1.5 1.6
[55]
THLE CTH
Mean 2.44
Standard deviation 0.065
Values 2.5 2.4
[56]
liver CTH
Mean 27.6
Standard deviation 15
Values 17 38 43 13
[57]
ref_hepatocyte GGT1
Mean 15.1
Standard deviation 12
Values 0.7 20 29 4.1 22
[58]
HepG2 GGT1
Mean 20.9
Standard deviation 6.9
Values 26 16
[59]
HepG2.C3A GGT1
Mean 15.5
Standard deviation 4.3
Values 19 12
[60]
HuH.7 GGT1
Mean 12.7
Standard deviation 3.6
Values 11 17 9.9
[61]
SNU475 GGT1
Mean 6.1
Standard deviation 1.7
Values 7.3 4.9
[62]
THLE GGT1
Mean 0.294
Standard deviation 0.0057
Values 0.29 0.3
[63]
liver GGT1
Mean 35.2
Standard deviation 23
Values 15 65 40 21
[64]
ref_hepatocyte MAT2B
Mean 12.1
Standard deviation 5.7
Values 13 9.7 9.4 6.8 21
[65]
HepG2 MAT2B
Mean 25.3
Standard deviation 2.8
Values 23 27
[66]
HepG2.C3A MAT2B
Mean 23.8
Standard deviation 7.6
Values 18 29
[67]
HuH.7 MAT2B
Mean 26.2
Standard deviation 6.2
Values 27 20 32
[68]
SNU475 MAT2B
Mean 30.8
Standard deviation 4.2
Values 34 28
[69]
THLE MAT2B
Mean 32
Standard deviation 4.5
Values 29 35
[70]
liver MAT2B
Mean 17.5
Standard deviation 7.4
Values 12 22 26 10
[71]
ref_hepatocyte PAPSS1
Mean 11.8
Standard deviation 18
Values 43 8.1 1.9 3.4 2.5
[72]
HepG2 PAPSS1
Mean 43
Standard deviation 11
Values 35 51
[73]
HepG2.C3A PAPSS1
Mean 52.7
Standard deviation 0.024
Values 53 53
[74]
HuH.7 PAPSS1
Mean 30.6
Standard deviation 3.2
Values 32 27 33
[75]
SNU475 PAPSS1
Mean 24.8
Standard deviation 9.8
Values 32 18
[76]
THLE PAPSS1
Mean 29.5
Standard deviation 0.55
Values 30 29
[77]
liver PAPSS1
Mean 5.95
Standard deviation 2
Values 6.1 7 7.7 3.1
[78]
ref_hepatocyte SEPHS1
Mean 11.3
Standard deviation 1.9
Values 11 8.3 13 13 11
[79]
HepG2 SEPHS1
Mean 40.8
Standard deviation 4.6
Values 38 44
[80]
HepG2.C3A SEPHS1
Mean 47.6
Standard deviation 17
Values 35 60
[81]
HuH.7 SEPHS1
Mean 42
Standard deviation 13
Values 50 27 50
[82]
SNU475 SEPHS1
Mean 49.7
Standard deviation 1.1
Values 49 51
[83]
THLE SEPHS1
Mean 32.3
Standard deviation 6.8
Values 28 37
[84]
liver SEPHS1
Mean 15.1
Standard deviation 2.6
Values 17 15 12 16
[85]
ref_hepatocyte TRMT11
Mean 9.7
Standard deviation 6.8
Values 13 20 4.7 4.7 6.2
[86]
HepG2 TRMT11
Mean 8.38
Standard deviation 2.2
Values 6.9 9.9
[87]
HepG2.C3A TRMT11
Mean 20
Standard deviation 2.4
Values 18 22
[88]
HuH.7 TRMT11
Mean 8.75
Standard deviation 1
Values 8.3 8 9.9
[89]
SNU475 TRMT11
Mean 5.76
Standard deviation 1.2
Values 6.6 4.9
[90]
THLE TRMT11
Mean 8.37
Standard deviation 1
Values 9.1 7.7
[91]
liver TRMT11
Mean 17.4
Standard deviation 2.6
Values 16 17 15 21
[92]
ref_hepatocyte METTL2B
Mean 7.43
Standard deviation 4
Values 6.8 12 3.8 11 3.5
[93]
HepG2 METTL2B
Mean 7.99
Standard deviation 0.55
Values 8.4 7.6
[94]
HepG2.C3A METTL2B
Mean 5.85
Standard deviation 0.67
Values 5.4 6.3
[95]
HuH.7 METTL2B
Mean 7.49
Standard deviation 2
Values 9.1 5.3 8
[96]
SNU475 METTL2B
Mean 6.1
Standard deviation 0.23
Values 6.3 5.9
[97]
THLE METTL2B
Mean 6.38
Standard deviation 1.3
Values 5.4 7.3
[98]
liver METTL2B
Mean 4.64
Standard deviation 1.4
Values 4.2 3 5 6.3
[99]
ref_hepatocyte SCLY
Mean 7.2
Standard deviation 4.4
Values 3.4 5.1 12 3.5 12
[100]
HepG2 SCLY
Mean 0.598
Standard deviation 0.28
Values 0.8 0.4
[101]
HepG2.C3A SCLY
Mean 0.307
Standard deviation 0.021
Values 0.29 0.32
[102]
HuH.7 SCLY
Mean 0.785
Standard deviation 0.18
Values 0.98 0.63 0.75
[103]
SNU475 SCLY
Mean 0.178
Standard deviation 0.035
Values 0.15 0.2
[104]
THLE SCLY
Mean 0.291
Standard deviation 0.23
Values 0.13 0.45
[105]
liver SCLY
Mean 0.235
Standard deviation 0.27
Values 0 0.54 0.39 0.013
[106]
ref_hepatocyte LCMT1
Mean 6.07
Standard deviation 3.6
Values 12 5.1 4.8 5.1 3.1
[107]
HepG2 LCMT1
Mean 22.5
Standard deviation 4.2
Values 25 20
[108]
HepG2.C3A LCMT1
Mean 20.3
Standard deviation 6.6
Values 25 16
[109]
HuH.7 LCMT1
Mean 16.9
Standard deviation 0.88
Values 16 17 17
[110]
SNU475 LCMT1
Mean 5.17
Standard deviation 0.64
Values 5.6 4.7
[111]
THLE LCMT1
Mean 8.72
Standard deviation 1.4
Values 7.7 9.7
[112]
liver LCMT1
Mean 2.39
Standard deviation 1.4
Values 1.6 2.9 4 0.99
[113]
ref_hepatocyte METTL6
Mean 3
Standard deviation 1.9
Values 5.1 4.7 1.1 3 1.2
[114]
HepG2 METTL6
Mean 8.55
Standard deviation 0.08
Values 8.5 8.6
[115]
HepG2.C3A METTL6
Mean 5.49
Standard deviation 1.9
Values 4.1 6.9
[116]
HuH.7 METTL6
Mean 8.41
Standard deviation 0.78
Values 8.5 7.6 9.1
[117]
SNU475 METTL6
Mean 5.41
Standard deviation 0.46
Values 5.1 5.7
[118]
THLE METTL6
Mean 8.46
Standard deviation 1
Values 7.7 9.2
[119]
liver METTL6
Mean 2.01
Standard deviation 0.52
Values 2.6 1.3 2 2.1
[120]
ref_hepatocyte MARS2
Mean 2.73
Standard deviation 1.5
Values 5.2 3 2.2 1.9 1.4
[121]
HepG2 MARS2
Mean 11
Standard deviation 0.62
Values 11 11
[122]
HepG2.C3A MARS2
Mean 7.57
Standard deviation 2.3
Values 5.9 9.2
[123]
HuH.7 MARS2
Mean 7.39
Standard deviation 1.5
Values 8.5 5.7 8
[124]
SNU475 MARS2
Mean 2.68
Standard deviation 0.7
Values 2.2 3.2
[125]
THLE MARS2
Mean 4.77
Standard deviation 0.75
Values 4.2 5.3
[126]
liver MARS2
Mean 7.25
Standard deviation 1.4
Values 8.2 5.3 8.2 7.3
[127]
ref_hepatocyte LCMT2
Mean 2.25
Standard deviation 0.7
Values 2.3 3.3 2 2.2 1.4
[128]
HepG2 LCMT2
Mean 5.24
Standard deviation 1.2
Values 4.4 6.1
[129]
HepG2.C3A LCMT2
Mean 3.55
Standard deviation 1.5
Values 2.5 4.6
[130]
HuH.7 LCMT2
Mean 3.13
Standard deviation 1.3
Values 3.3 1.7 4.3
[131]
SNU475 LCMT2
Mean 4.54
Standard deviation 0.52
Values 4.2 4.9
[132]
THLE LCMT2
Mean 6.07
Standard deviation 2.1
Values 4.6 7.5
[133]
liver LCMT2
Mean 4.19
Standard deviation 0.63
Values 3.6 4.9 4.5 3.8
[134]
ref_hepatocyte HEMK1
Mean 1.7
Standard deviation 0.85
Values 0.64 1.1 2.5 1.8 2.5
[135]
HepG2 HEMK1
Mean 4.92
Standard deviation 0.4
Values 5.2 4.6
[136]
HepG2.C3A HEMK1
Mean 9.92
Standard deviation 2.2
Values 11 8.4
[137]
HuH.7 HEMK1
Mean 10.7
Standard deviation 1.1
Values 9.8 10 12
[138]
SNU475 HEMK1
Mean 4.99
Standard deviation 1.1
Values 5.8 4.2
[139]
THLE HEMK1
Mean 6.44
Standard deviation 0.076
Values 6.5 6.4
[140]
liver HEMK1
Mean 8.82
Standard deviation 1.6
Values 7.3 9 8 11
[141]
ref_hepatocyte GGT7
Mean 1.61
Standard deviation 1.1
Values 1.5 0.71 2.8 0.35 2.6
[142]
HepG2 GGT7
Mean 12.2
Standard deviation 0.96
Values 13 12
[143]
HepG2.C3A GGT7
Mean 13.6
Standard deviation 5.5
Values 18 9.8
[144]
HuH.7 GGT7
Mean 9.57
Standard deviation 2.2
Values 7.5 12 9.5
[145]
SNU475 GGT7
Mean 11.5
Standard deviation 1.7
Values 13 10
[146]
THLE GGT7
Mean 7.01
Standard deviation 1.9
Values 8.3 5.7
[147]
liver GGT7
Mean 2.93
Standard deviation 1
Values 4.2 2.2 2.1 3.3
[148]
ref_hepatocyte AHCYL2
Mean 1.01
Standard deviation 0.32
Values 0.94 1.3 1.3 0.52 0.99
[149]
HepG2 AHCYL2
Mean 7.93
Standard deviation 1.2
Values 7.1 8.7
[150]
HepG2.C3A AHCYL2
Mean 7.77
Standard deviation 1.3
Values 8.7 6.8
[151]
HuH.7 AHCYL2
Mean 7.85
Standard deviation 0.49
Values 7.9 8.3 7.3
[152]
SNU475 AHCYL2
Mean 8.63
Standard deviation 1
Values 9.3 7.9
[153]
THLE AHCYL2
Mean 9.83
Standard deviation 1
Values 9.1 11
[154]
liver AHCYL2
Mean 5.46
Standard deviation 2.4
Values 8.3 3.7 3.4 6.4
[155]
ref_hepatocyte GGT6
Mean 0.301
Standard deviation 0.36
Values 0.92 0.06 0.06 0.2 0.28
[156]
HepG2 GGT6
Mean 0.834
Standard deviation 0.027
Values 0.85 0.82
[157]
HepG2.C3A GGT6
Mean 1.08
Standard deviation 0.082
Values 1 1.1
[158]
HuH.7 GGT6
Mean 0.31
Standard deviation 0.14
Values 0.24 0.47 0.22
[159]
SNU475 GGT6
Mean 0.28
Standard deviation 0.044
Values 0.31 0.25
[160]
THLE GGT6
Mean 0.19
Standard deviation 0.077
Values 0.14 0.24
[161]
liver GGT6
Mean 0.426
Standard deviation 0.13
Values 0.3 0.61 0.41 0.38
[162]
ref_hepatocyte GGT5
Mean 0.17
Standard deviation 0.18
Values 0.15 0 0.41 0 0.3
[163]
HepG2 GGT5
Mean 8.97
Standard deviation 6.7
Values 14 4.3
[164]
HepG2.C3A GGT5
Mean 1.3
Standard deviation 0.47
Values 0.97 1.6
[165]
HuH.7 GGT5
Mean 0.0424
Standard deviation 0.034
Values 0.074 0.0064 0.047
[166]
SNU475 GGT5
Mean 4.71
Standard deviation 2.8
Values 2.7 6.7
[167]
THLE GGT5
Mean 5.79
Standard deviation 1.9
Values 4.5 7.1
[168]
liver GGT5
Mean 12
Standard deviation 7.3
Values 4.2 13 21 9.1
[169]
ref_hepatocyte BUD23
Missing
[170]
HepG2 BUD23
Missing
[171]
HepG2.C3A BUD23
Missing
[172]
HuH.7 BUD23
Missing
[173]
SNU475 BUD23
Missing
[174]
THLE BUD23
Missing
[175]
liver BUD23
Missing
[176]
ref_hepatocyte MARS1
Missing
[177]
HepG2 MARS1
Missing
[178]
HepG2.C3A MARS1
Missing
[179]
HuH.7 MARS1
Missing
[180]
SNU475 MARS1
Missing
[181]
THLE MARS1
Missing
[182]
liver MARS1
Missing