KEGG_RETINOL_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ADH1B Alcohol dehydrogenase 1B [1] -9.85[2] [3] -7.36[4] [5] [6] 0.17[7]
2 ADH4 Alcohol dehydrogenase 4 [8] -2.63[9] -3.38[10] -8.60[11] -11.70[12] -7.51[13] -2.35[14]
3 ALDH1A1 Retinal dehydrogenase 1 [15] 2.32[16] 1.25[17] 3.26[18] 3.34[19] -2.80[20] -1.28[21]
4 ADH1A Alcohol dehydrogenase 1A [22] -11.26[23] [24] -7.96[25] -14.79[26] [27] -1.82[28]
5 CYP2C8 Cytochrome P450 2C8 [29] -12.66[30] -8.17[31] -6.99[32] -10.30[33] [34] 0.63[35]
6 CYP2C9 Cytochrome P450 2C9 [36] [37] -13.08[38] -7.21[39] -12.99[40] -9.95[41] 1.14[42]
7 CYP3A4 Cytochrome P450 3A4 [43] -7.92[44] -8.28[45] -11.02[46] -13.30[47] -9.53[48] 0.85[49]
8 UGT1A6 UDP-glucuronosyltransferase 1-6 [50] -5.01[51] -12.98[52] -8.12[53] -4.65[54] -8.26[55] -3.77[56]
9 CYP2A6 Cytochrome P450 2A6 [57] -14.03[58] [59] -7.45[60] -10.06[61] -10.26[62] -1.50[63]
10 UGT2B4 UDP-glucuronosyltransferase 2B4 [64] -5.62[65] -6.03[66] -1.81[67] -7.89[68] -9.15[69] 0.89[70]
11 RDH16 Retinol dehydrogenase 16 [71] -8.42[72] -6.68[73] -7.47[74] -8.09[75] -6.50[76] -0.57[77]
12 CYP3A5 Cytochrome P450 3A5 [78] -2.98[79] -0.99[80] -4.77[81] -5.87[82] -5.86[83] 1.21[84]
13 ADH1C Alcohol dehydrogenase 1C [85] -11.64[86] -9.70[87] -9.35[88] -8.60[89] -8.72[90] -1.00[91]
14 UGT2B7 UDP-glucuronosyltransferase 2B7 [92] 0.49[93] 0.40[94] -6.10[95] -9.10[96] -8.44[97] -0.40[98]
15 CYP4A11 Cytochrome P450 4A11 [99] -10.84[100] -8.45[101] -11.34[102] -9.12[103] -7.90[104] 0.99[105]
16 UGT2B10 UDP-glucuronosyltransferase 2B10 [106] 0.06[107] 2.45[108] -6.23[109] -9.23[110] -10.47[111] -1.49[112]
17 CYP1A2 Cytochrome P450 1A2 [113] -7.09[114] -6.03[115] -7.72[116] -6.87[117] -5.06[118] -1.54[119]
18 ADH6 Alcohol dehydrogenase 6 [120] 0.28[121] 0.81[122] -0.13[123] -7.60[124] -5.55[125] -0.58[126]
19 UGT2B15 UDP-glucuronosyltransferase 2B15 [127] -7.85[128] -6.53[129] -6.85[130] -8.97[131] -7.28[132] -0.87[133]
20 UGT1A1 UDP-glucuronosyltransferase 1-1 [134] -2.54[135] -9.03[136] -4.90[137] 0.87[138] -6.90[139] 0.07[140]
21 ADH5 Alcohol dehydrogenase class-3 [141] 3.54[142] 3.28[143] 2.78[144] 2.13[145] 4.64[146] -0.24[147]
22 DHRS3 Short-chain dehydrogenase/reductase 3 [148] 1.50[149] 2.33[150] 0.04[151] 1.22[152] 3.13[153] 0.43[154]
23 UGT1A4 UDP-glucuronosyltransferase 1-4 [155] -9.91[156] [157] -10.80[158] -8.41[159] [160] 0.25[161]
24 CYP2B6 Cytochrome P450 2B6 [162] -5.81[163] -2.62[164] -2.27[165] -7.85[166] -6.63[167] 2.52[168]
25 RDH11 Retinol dehydrogenase 11 [169] 1.71[170] 2.97[171] 1.93[172] 1.54[173] 3.86[174] 0.62[175]
26 CYP1A1 Cytochrome P450 1A1 [176] -0.64[177] -2.46[178] 0.17[179] -2.27[180] -0.58[181] -5.68[182]
27 CYP2C18 Cytochrome P450 2C18 [183] -7.64[184] -9.35[185] -4.53[186] -10.13[187] -5.96[188] -0.34[189]
28 DGAT2 Diacylglycerol O-acyltransferase 2 [190] 3.16[191] 2.06[192] 0.13[193] -1.31[194] 2.27[195] 0.60[196]
29 DHRS4 Dehydrogenase/reductase SDR family member 4 [197] 0.71[198] -1.79[199] -1.93[200] -1.44[201] 0.37[202] -2.28[203]
30 CYP3A7 Cytochrome P450 3A7 [204] -3.10[205] -1.07[206] -6.82[207] [208] -7.32[209] -1.55[210]
31 DHRS4L2 Dehydrogenase/reductase SDR family member 4-like 2 [211] 0.51[212] -2.16[213] -2.30[214] -1.65[215] -0.37[216] -2.38[217]
32 RDH5 11-cis retinol dehydrogenase [218] -3.97[219] -2.23[220] -3.25[221] -5.26[222] -2.51[223] -2.69[224]
33 RETSAT All-trans-retinol 13,14-reductase [225] 3.66[226] 4.07[227] 1.90[228] 2.34[229] 3.99[230] 0.55[231]
34 CYP2C19 Cytochrome P450 2C19 [232] [233] [234] -4.35[235] -10.68[236] -8.26[237] 1.69[238]
35 UGT1A9 UDP-glucuronosyltransferase 1-9 [239] -3.88[240] -8.99[241] -6.21[242] -3.46[243] -6.49[244] -0.52[245]
36 CYP2A7 Cytochrome P450 2A7 [246] [247] [248] -2.86[249] -8.66[250] [251] -1.65[252]
37 DHRS9 Dehydrogenase/reductase SDR family member 9 [253] -4.70[254] -5.12[255] -7.44[256] -2.78[257] -0.12[258] -5.74[259]
38 UGT2B17 UDP-glucuronosyltransferase 2B17 [260] -7.20[261] -6.82[262] -10.66[263] [264] [265] -1.24[266]
39 UGT2A3 UDP-glucuronosyltransferase 2A3 [267] 5.11[268] 6.73[269] -1.70[270] -3.83[271] -4.44[272] 1.62[273]
40 RDH10 Retinol dehydrogenase 10 [274] 3.95[275] 4.43[276] 2.34[277] 3.66[278] 4.48[279] 1.12[280]
41 DGAT1 Diacylglycerol O-acyltransferase 1 [281] 5.13[282] 4.73[283] 4.19[284] 2.89[285] 4.97[286] 0.32[287]
42 UGT1A3 UDP-glucuronosyltransferase 1-3 [288] 0.87[289] [290] -7.06[291] -3.20[292] -6.08[293] 1.36[294]
43 PNPLA4 Patatin-like phospholipase domain-containing protein 4 [295] 3.67[296] 3.44[297] 2.54[298] 2.13[299] 5.69[300] 0.53[301]
44 CYP4A22 Cytochrome P450 4A22 [302] [303] [304] [305] [306] [307] 2.38[308]
45 CYP3A43 Cytochrome P450 3A43 [309] -1.03[310] 1.63[311] 0.42[312] [313] -4.70[314] 1.50[315]
46 RDH12 Retinol dehydrogenase 12 [316] 2.61[317] 4.52[318] -3.28[319] -1.39[320] 1.15[321] 0.47[322]
47 UGT1A5 UDP-glucuronosyltransferase 1-5 [323] -2.42[324] [325] -4.88[326] -0.06[327] [328] 1.42[329]
48 UGT2B11 UDP-glucuronosyltransferase 2B11 [330] 4.04[331] 2.45[332] 2.67[333] -3.06[334] [335] 0.93[336]
49 UGT2B28 UDP-glucuronosyltransferase 2B28 [337] 3.81[338] 4.09[339] -1.19[340] -3.65[341] [342] 0.89[343]
50 CYP26A1 Cytochrome P450 26A1 [344] 6.99[345] 0.92[346] 3.44[347] 3.37[348] -0.09[349] 1.12[350]
51 ALDH1A2 Retinal dehydrogenase 2 [351] -0.11[352] -0.25[353] 2.11[354] 2.42[355] 12.23[356] 2.32[357]
52 LRAT Lecithin retinol acyltransferase [358] 2.13[359] 2.47[360] 0.22[361] 1.78[362] 4.61[363] 5.31[364]
53 CYP2A13 Cytochrome P450 2A13 [365] [366] [367] [368] [369] [370] -0.40[371]
54 UGT1A7 UDP-glucuronosyltransferase 1-7 [372] 3.00[373] [374] 1.01[375] 7.91[376] 4.77[377] 3.36[378]
55 ADH7 Alcohol dehydrogenase class 4 mu/sigma chain [379] [380] [381] [382] [383] [384] -2.89[385]
56 CYP26B1 Cytochrome P450 26B1 [386] 8.72[387] 5.43[388] 11.61[389] 9.92[390] 11.38[391] 5.65[392]
57 UGT1A10 UDP-glucuronosyltransferase 1-10 [393] [394] [395] [396] [397] [398] [399]
58 UGT1A8 UDP-glucuronosyltransferase 1-8 [400] [401] [402] [403] [404] [405] [406]
59 AWAT2 Acyl-CoA wax alcohol acyltransferase 2 [407] [408] [409] [410] [411] [412] [413]
60 CYP26C1 Cytochrome P450 26C1 [414] [415] [416] [417] [418] [419] [420]
61 RPE65 Retinoid isomerohydrolase [421] [422] [423] [424] [425] [426] [427]
62 BCO1 Beta,beta-carotene 15,15'-dioxygenase [428] [429] [430] [431] [432] [433] [434]
63 UGT2A1 UDP-glucuronosyltransferase 2A1 [435] [436] [437] [438] [439] [440] [441]
64 RDH8 Retinol dehydrogenase 8 [442] [443] [444] [445] [446] [447] [448]
[1]
ref_hepatocyte ADH1B
Mean 512
Standard deviation 8.3e+02
Values 0.096 0.69 6.3e+02 6.9 1.9e+03
[2]
HepG2 ADH1B
Mean 0.0866
Standard deviation 0.017
Values 0.074 0.099
[3]
HepG2.C3A ADH1B
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 ADH1B
Mean 0.991
Standard deviation 1.6
Values 0.049 2.9 0.028
[5]
SNU475 ADH1B
Mean 0
Standard deviation 0
Values 0 0
[6]
THLE ADH1B
Mean 0
Standard deviation 0
Values 0 0
[7]
liver ADH1B
Mean 756
Standard deviation 3.8e+02
Values 5.3e+02 1.3e+03 5.5e+02 6.2e+02
[8]
ref_hepatocyte ADH4
Mean 397
Standard deviation 7e+02
Values 29 4.9 3.3e+02 1.5 1.6e+03
[9]
HepG2 ADH4
Mean 9.95
Standard deviation 0.32
Values 9.7 10
[10]
HepG2.C3A ADH4
Mean 6.21
Standard deviation 2.8
Values 4.3 8.2
[11]
HuH.7 ADH4
Mean 0.326
Standard deviation 0.33
Values 0.2 0.71 0.075
[12]
SNU475 ADH4
Mean 0.0236
Standard deviation 0.019
Values 0.037 0.01
[13]
THLE ADH4
Mean 0.103
Standard deviation 0.02
Values 0.089 0.12
[14]
liver ADH4
Mean 102
Standard deviation 66
Values 40 1.9e+02 58 1.2e+02
[15]
ref_hepatocyte ALDH1A1
Mean 382
Standard deviation 2.7e+02
Values 4.1e+02 7.6e+02 2.8e+02 20 4.3e+02
[16]
HepG2 ALDH1A1
Mean 298
Standard deviation 51
Values 2.6e+02 3.3e+02
[17]
HepG2.C3A ALDH1A1
Mean 148
Standard deviation 48
Values 1.1e+02 1.8e+02
[18]
HuH.7 ALDH1A1
Mean 1.17e+03
Standard deviation 3.9e+02
Values 1.4e+03 7.1e+02 1.4e+03
[19]
SNU475 ALDH1A1
Mean 768
Standard deviation 3.3e+02
Values 1e+03 5.4e+02
[20]
THLE ALDH1A1
Mean 2.59
Standard deviation 1.5
Values 3.6 1.6
[21]
liver ALDH1A1
Mean 207
Standard deviation 1.4e+02
Values 2.8e+02 1.2e+02 3.6e+02 68
[22]
ref_hepatocyte ADH1A
Mean 362
Standard deviation 6e+02
Values 0 0.45 4.1e+02 9.8 1.4e+03
[23]
HepG2 ADH1A
Mean 0.0229
Standard deviation 0.016
Values 0.011 0.034
[24]
HepG2.C3A ADH1A
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 ADH1A
Mean 0.465
Standard deviation 0.75
Values 0.057 1.3 0.0094
[26]
SNU475 ADH1A
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[27]
THLE ADH1A
Mean 0
Standard deviation 0
Values 0 0
[28]
liver ADH1A
Mean 135
Standard deviation 1.5e+02
Values 47 3.6e+02 93 38
[29]
ref_hepatocyte CYP2C8
Mean 328
Standard deviation 4.4e+02
Values 0 1.2 7.1e+02 19 9.1e+02
[30]
HepG2 CYP2C8
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[31]
HepG2.C3A CYP2C8
Mean 0.186
Standard deviation 0.071
Values 0.14 0.24
[32]
HuH.7 CYP2C8
Mean 0.822
Standard deviation 1
Values 0.16 2 0.3
[33]
SNU475 CYP2C8
Mean 0.0515
Standard deviation 0.02
Values 0.037 0.066
[34]
THLE CYP2C8
Mean 0
Standard deviation 0
Values 0 0
[35]
liver CYP2C8
Mean 666
Standard deviation 3.9e+02
Values 6.2e+02 6.8e+02 1.2e+03 2e+02
[36]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 0.064 20 4.7e+02 21 9.2e+02
[37]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[38]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[39]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[40]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[41]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[42]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 6.1e+02 8.6e+02 1.5e+03 2.9e+02
[43]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 0.24 11 3.2e+02 11 9.6e+02
[44]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.097 0.24
[45]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.068 0.2
[46]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.0082 0.064 0.047
[47]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[48]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[49]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 6.4e+02 4.3e+02 1.3e+03 49
[50]
ref_hepatocyte UGT1A6
Mean 242
Standard deviation 2.6e+02
Values 0.45 1.7e+02 4.3e+02 11 5.9e+02
[51]
HepG2 UGT1A6
Mean 1.17
Standard deviation 0.86
Values 1.8 0.56
[52]
HepG2.C3A UGT1A6
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[53]
HuH.7 UGT1A6
Mean 0.277
Standard deviation 0.33
Values 0.041 0.65 0.14
[54]
SNU475 UGT1A6
Mean 1.9
Standard deviation 0.11
Values 2 1.8
[55]
THLE UGT1A6
Mean 0.0372
Standard deviation 0.053
Values 0 0.074
[56]
liver UGT1A6
Mean 23.2
Standard deviation 17
Values 34 9 42 8.2
[57]
ref_hepatocyte CYP2A6
Mean 231
Standard deviation 3e+02
Values 0 4.6 5.6e+02 38 5.5e+02
[58]
HepG2 CYP2A6
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[59]
HepG2.C3A CYP2A6
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 CYP2A6
Mean 0.421
Standard deviation 0.53
Values 0.11 1 0.12
[61]
SNU475 CYP2A6
Mean 0.0428
Standard deviation 0.025
Values 0.06 0.025
[62]
THLE CYP2A6
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[63]
liver CYP2A6
Mean 107
Standard deviation 1e+02
Values 1.8e+02 29 2.1e+02 13
[64]
ref_hepatocyte UGT2B4
Mean 210
Standard deviation 2.5e+02
Values 0.056 68 4.6e+02 15 5e+02
[65]
HepG2 UGT2B4
Mean 0.666
Standard deviation 0.42
Values 0.96 0.37
[66]
HepG2.C3A UGT2B4
Mean 0.523
Standard deviation 0.23
Values 0.36 0.69
[67]
HuH.7 UGT2B4
Mean 19.1
Standard deviation 13
Values 11 34 12
[68]
SNU475 UGT2B4
Mean 0.176
Standard deviation 0.04
Values 0.2 0.15
[69]
THLE UGT2B4
Mean 0.0175
Standard deviation 0.017
Values 0.03 0.0053
[70]
liver UGT2B4
Mean 509
Standard deviation 93
Values 5.3e+02 4.5e+02 6.3e+02 4.3e+02
[71]
ref_hepatocyte RDH16
Mean 193
Standard deviation 2.8e+02
Values 0 0.34 3.4e+02 10 6.1e+02
[72]
HepG2 RDH16
Mean 0.0873
Standard deviation 0.014
Values 0.097 0.077
[73]
HepG2.C3A RDH16
Mean 0.306
Standard deviation 0.16
Values 0.42 0.19
[74]
HuH.7 RDH16
Mean 0.346
Standard deviation 0.14
Values 0.24 0.3 0.51
[75]
SNU475 RDH16
Mean 0.14
Standard deviation 0.046
Values 0.11 0.17
[76]
THLE RDH16
Mean 0.101
Standard deviation 0.067
Values 0.15 0.053
[77]
liver RDH16
Mean 170
Standard deviation 54
Values 91 2.1e+02 2.1e+02 1.7e+02
[78]
ref_hepatocyte CYP3A5
Mean 139
Standard deviation 1.6e+02
Values 22 55 2e+02 35 3.9e+02
[79]
HepG2 CYP3A5
Mean 2.75
Standard deviation 2.1
Values 1.3 4.2
[80]
HepG2.C3A CYP3A5
Mean 11.4
Standard deviation 3.8
Values 14 8.7
[81]
HuH.7 CYP3A5
Mean 1.63
Standard deviation 1.6
Values 0.58 3.5 0.83
[82]
SNU475 CYP3A5
Mean 0.471
Standard deviation 0.12
Values 0.56 0.39
[83]
THLE CYP3A5
Mean 0.113
Standard deviation 0.032
Values 0.14 0.09
[84]
liver CYP3A5
Mean 424
Standard deviation 3.2e+02
Values 2.7e+02 9e+02 2.5e+02 2.8e+02
[85]
ref_hepatocyte ADH1C
Mean 132
Standard deviation 2e+02
Values 0.14 2.1 2e+02 4 4.5e+02
[86]
HepG2 ADH1C
Mean 0.00643
Standard deviation 0.0091
Values 0 0.013
[87]
HepG2.C3A ADH1C
Mean 0.0258
Standard deviation 0.009
Values 0.019 0.032
[88]
HuH.7 ADH1C
Mean 0.0645
Standard deviation 0.029
Values 0.041 0.096 0.056
[89]
SNU475 ADH1C
Mean 0.0673
Standard deviation 0.062
Values 0.023 0.11
[90]
THLE ADH1C
Mean 0.0148
Standard deviation 0.021
Values 0.03 0
[91]
liver ADH1C
Mean 86.2
Standard deviation 1.1e+02
Values 32 2.6e+02 44 13
[92]
ref_hepatocyte UGT2B7
Mean 122
Standard deviation 1.9e+02
Values 3.3 8.1 1.6e+02 5.3 4.3e+02
[93]
HepG2 UGT2B7
Mean 26.6
Standard deviation 9
Values 33 20
[94]
HepG2.C3A UGT2B7
Mean 26.2
Standard deviation 13
Values 17 35
[95]
HuH.7 UGT2B7
Mean 0.568
Standard deviation 0.44
Values 0.3 1.1 0.34
[96]
SNU475 UGT2B7
Mean 0.0439
Standard deviation 0.0096
Values 0.037 0.051
[97]
THLE UGT2B7
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[98]
liver UGT2B7
Mean 121
Standard deviation 61
Values 77 1.7e+02 1.7e+02 61
[99]
ref_hepatocyte CYP4A11
Mean 109
Standard deviation 1.6e+02
Values 0 0 2e+02 4 3.4e+02
[100]
HepG2 CYP4A11
Mean 0.0093
Standard deviation 0.005
Values 0.0057 0.013
[101]
HepG2.C3A CYP4A11
Mean 0.0511
Standard deviation 0.0036
Values 0.049 0.054
[102]
HuH.7 CYP4A11
Mean 0.0135
Standard deviation 0.0098
Values 0.025 0.0064 0.0094
[103]
SNU475 CYP4A11
Mean 0.039
Standard deviation 0.0093
Values 0.032 0.046
[104]
THLE CYP4A11
Mean 0.0216
Standard deviation 0.022
Values 0.0059 0.037
[105]
liver CYP4A11
Mean 286
Standard deviation 2.2e+02
Values 87 5.7e+02 3.6e+02 1.3e+02
[106]
ref_hepatocyte UGT2B10
Mean 89.2
Standard deviation 1.3e+02
Values 13 1.3 1.2e+02 2.6 3.1e+02
[107]
HepG2 UGT2B10
Mean 14.5
Standard deviation 5.1
Values 11 18
[108]
HepG2.C3A UGT2B10
Mean 79.3
Standard deviation 33
Values 56 1e+02
[109]
HuH.7 UGT2B10
Mean 0.379
Standard deviation 0.38
Values 0.098 0.82 0.22
[110]
SNU475 UGT2B10
Mean 0.0293
Standard deviation 0.0087
Values 0.023 0.035
[111]
THLE UGT2B10
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[112]
liver UGT2B10
Mean 41.7
Standard deviation 22
Values 68 16 33 50
[113]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.4 18 71 0.97 3e+02
[114]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.052 0.13
[115]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.24 0.15
[116]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.11 0.1 0.15
[117]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.07 0.2
[118]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[119]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 12 55 58 19
[120]
ref_hepatocyte ADH6
Mean 72.8
Standard deviation 92
Values 50 11 72 1.2 2.3e+02
[121]
HepG2 ADH6
Mean 13.8
Standard deviation 5.3
Values 10 17
[122]
HepG2.C3A ADH6
Mean 20.8
Standard deviation 0.45
Values 21 20
[123]
HuH.7 ADH6
Mean 21.2
Standard deviation 7
Values 19 29 15
[124]
SNU475 ADH6
Mean 0.0743
Standard deviation 0.053
Values 0.037 0.11
[125]
THLE ADH6
Mean 0.0733
Standard deviation 0.013
Values 0.083 0.064
[126]
liver ADH6
Mean 63.7
Standard deviation 33
Values 30 1.1e+02 46 74
[127]
ref_hepatocyte UGT2B15
Mean 72.3
Standard deviation 99
Values 0.2 13 1.2e+02 3.3 2.3e+02
[128]
HepG2 UGT2B15
Mean 0.0487
Standard deviation 0.004
Values 0.046 0.051
[129]
HepG2.C3A UGT2B15
Mean 0.127
Standard deviation 0.013
Values 0.14 0.12
[130]
HuH.7 UGT2B15
Mean 0.2
Standard deviation 0.22
Values 0.066 0.45 0.084
[131]
SNU475 UGT2B15
Mean 0.0285
Standard deviation 0.019
Values 0.042 0.015
[132]
THLE UGT2B15
Mean 0.0219
Standard deviation 0.014
Values 0.012 0.032
[133]
liver UGT2B15
Mean 52
Standard deviation 21
Values 56 66 64 21
[134]
ref_hepatocyte UGT1A1
Mean 67.2
Standard deviation 89
Values 0.52 12 2.1e+02 15 96
[135]
HepG2 UGT1A1
Mean 1.8
Standard deviation 0.2
Values 1.9 1.7
[136]
HepG2.C3A UGT1A1
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[137]
HuH.7 UGT1A1
Mean 0.72
Standard deviation 0.5
Values 0.57 1.3 0.31
[138]
SNU475 UGT1A1
Mean 24.4
Standard deviation 21
Values 39 9.8
[139]
THLE UGT1A1
Mean 0.0266
Standard deviation 0.038
Values 0 0.053
[140]
liver UGT1A1
Mean 92.4
Standard deviation 46
Values 83 1.1e+02 1.4e+02 34
[141]
ref_hepatocyte ADH5
Mean 65.9
Standard deviation 32
Values 84 59 61 19 1.1e+02
[142]
HepG2 ADH5
Mean 119
Standard deviation 17
Values 1.1e+02 1.3e+02
[143]
HepG2.C3A ADH5
Mean 104
Standard deviation 26
Values 86 1.2e+02
[144]
HuH.7 ADH5
Mean 144
Standard deviation 17
Values 1.3e+02 1.4e+02 1.6e+02
[145]
SNU475 ADH5
Mean 57.2
Standard deviation 13
Values 66 48
[146]
THLE ADH5
Mean 77.4
Standard deviation 11
Values 69 85
[147]
liver ADH5
Mean 73.2
Standard deviation 37
Values 49 1.2e+02 76 43
[148]
ref_hepatocyte DHRS3
Mean 60.2
Standard deviation 46
Values 13 28 97 44 1.2e+02
[149]
HepG2 DHRS3
Mean 26.5
Standard deviation 1.6
Values 28 25
[150]
HepG2.C3A DHRS3
Mean 49.5
Standard deviation 22
Values 65 34
[151]
HuH.7 DHRS3
Mean 19.8
Standard deviation 4.5
Values 17 25 18
[152]
SNU475 DHRS3
Mean 27.7
Standard deviation 3.2
Values 30 25
[153]
THLE DHRS3
Mean 24.9
Standard deviation 3.5
Values 27 22
[154]
liver DHRS3
Mean 107
Standard deviation 71
Values 49 1.4e+02 1.9e+02 46
[155]
ref_hepatocyte UGT1A4
Mean 53.1
Standard deviation 73
Values 0 4.2 99 2.5 1.6e+02
[156]
HepG2 UGT1A4
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[157]
HepG2.C3A UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 UGT1A4
Mean 0.00954
Standard deviation 0.0096
Values 0 0.019 0.0094
[159]
SNU475 UGT1A4
Mean 0.031
Standard deviation 0.015
Values 0.042 0.02
[160]
THLE UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[161]
liver UGT1A4
Mean 83.1
Standard deviation 65
Values 95 36 1.7e+02 32
[162]
ref_hepatocyte CYP2B6
Mean 49.6
Standard deviation 62
Values 0 4.1 1.3e+02 12 1e+02
[163]
HepG2 CYP2B6
Mean 0.138
Standard deviation 0.15
Values 0.24 0.034
[164]
HepG2.C3A CYP2B6
Mean 1.32
Standard deviation 0.56
Values 1.7 0.92
[165]
HuH.7 CYP2B6
Mean 3.27
Standard deviation 2.3
Values 2.1 5.9 1.9
[166]
SNU475 CYP2B6
Mean 0.0424
Standard deviation 0.04
Values 0.014 0.071
[167]
THLE CYP2B6
Mean 0.0237
Standard deviation 0.033
Values 0.047 0
[168]
liver CYP2B6
Mean 372
Standard deviation 5.3e+02
Values 3.2e+02 23 1.1e+03 7.4
[169]
ref_hepatocyte RDH11
Mean 49.5
Standard deviation 12
Values 38 60 54 36 60
[170]
HepG2 RDH11
Mean 25.2
Standard deviation 3.8
Values 23 28
[171]
HepG2.C3A RDH11
Mean 63.3
Standard deviation 21
Values 78 49
[172]
HuH.7 RDH11
Mean 60.2
Standard deviation 6.3
Values 54 67 60
[173]
SNU475 RDH11
Mean 28.5
Standard deviation 0.012
Values 28 29
[174]
THLE RDH11
Mean 33.8
Standard deviation 2.5
Values 32 36
[175]
liver RDH11
Mean 99.7
Standard deviation 22
Values 89 1.1e+02 1.3e+02 77
[176]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 77 43 17 0.06 82
[177]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 6.2 2.6
[178]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.4 1.2
[179]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 14 17 17
[180]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 0.49 3.1
[181]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[182]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 0.47 1.2 0.92 1.8
[183]
ref_hepatocyte CYP2C18
Mean 43
Standard deviation 35
Values 0 90 51 18 56
[184]
HepG2 CYP2C18
Mean 0.0336
Standard deviation 0.017
Values 0.046 0.021
[185]
HepG2.C3A CYP2C18
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[186]
HuH.7 CYP2C18
Mean 0.593
Standard deviation 0.1
Values 0.53 0.71 0.53
[187]
SNU475 CYP2C18
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[188]
THLE CYP2C18
Mean 0.0325
Standard deviation 0.029
Values 0.012 0.053
[189]
liver CYP2C18
Mean 44.5
Standard deviation 13
Values 57 36 54 31
[190]
ref_hepatocyte DGAT2
Mean 37.5
Standard deviation 34
Values 8 14 44 30 92
[191]
HepG2 DGAT2
Mean 52.1
Standard deviation 17
Values 40 64
[192]
HepG2.C3A DGAT2
Mean 25.5
Standard deviation 7.2
Values 20 31
[193]
HuH.7 DGAT2
Mean 13.1
Standard deviation 1.5
Values 12 15 12
[194]
SNU475 DGAT2
Mean 3
Standard deviation 1.1
Values 2.2 3.8
[195]
THLE DGAT2
Mean 8.53
Standard deviation 0.85
Values 7.9 9.1
[196]
liver DGAT2
Mean 74.5
Standard deviation 63
Values 23 1.6e+02 45 65
[197]
ref_hepatocyte DHRS4
Mean 36.8
Standard deviation 23
Values 34 24 45 9.7 71
[198]
HepG2 DHRS4
Mean 9.37
Standard deviation 1.4
Values 8.4 10
[199]
HepG2.C3A DHRS4
Mean 1.73
Standard deviation 0.2
Values 1.9 1.6
[200]
HuH.7 DHRS4
Mean 3.07
Standard deviation 0.58
Values 3.2 2.5 3.6
[201]
SNU475 DHRS4
Mean 2.69
Standard deviation 1.2
Values 3.5 1.9
[202]
THLE DHRS4
Mean 2.24
Standard deviation 0.27
Values 2.1 2.4
[203]
liver DHRS4
Mean 9.96
Standard deviation 5
Values 5.5 17 11 7
[204]
ref_hepatocyte CYP3A7
Mean 29.1
Standard deviation 41
Values 8.7 0.12 1e+02 5 32
[205]
HepG2 CYP3A7
Mean 0.531
Standard deviation 0.38
Values 0.26 0.8
[206]
HepG2.C3A CYP3A7
Mean 2.26
Standard deviation 0.013
Values 2.3 2.3
[207]
HuH.7 CYP3A7
Mean 0.0822
Standard deviation 0.074
Values 0.033 0.17 0.047
[208]
SNU475 CYP3A7
Mean 0
Standard deviation 0
Values 0 0
[209]
THLE CYP3A7
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[210]
liver CYP3A7
Mean 13
Standard deviation 12
Values 5.2 30 11 5.1
[211]
ref_hepatocyte DHRS4L2
Mean 28.7
Standard deviation 19
Values 36 14 35 5.3 52
[212]
HepG2 DHRS4L2
Mean 6.34
Standard deviation 0.46
Values 6 6.7
[213]
HepG2.C3A DHRS4L2
Mean 1.05
Standard deviation 0.0067
Values 1 1
[214]
HuH.7 DHRS4L2
Mean 1.86
Standard deviation 0.56
Values 1.7 1.4 2.5
[215]
SNU475 DHRS4L2
Mean 1.8
Standard deviation 0.76
Values 2.3 1.3
[216]
THLE DHRS4L2
Mean 1.05
Standard deviation 0.12
Values 0.96 1.1
[217]
liver DHRS4L2
Mean 7.25
Standard deviation 6.4
Values 2.2 15 9.1 2.2
[218]
ref_hepatocyte RDH5
Mean 23.8
Standard deviation 26
Values 0.53 17 35 3.6 64
[219]
HepG2 RDH5
Mean 0.238
Standard deviation 0.045
Values 0.27 0.21
[220]
HepG2.C3A RDH5
Mean 0.829
Standard deviation 0.051
Values 0.87 0.79
[221]
HuH.7 RDH5
Mean 0.802
Standard deviation 0.21
Values 0.58 0.99 0.83
[222]
SNU475 RDH5
Mean 0.123
Standard deviation 0.023
Values 0.14 0.11
[223]
THLE RDH5
Mean 0.198
Standard deviation 0.021
Values 0.18 0.21
[224]
liver RDH5
Mean 4.84
Standard deviation 3.7
Values 4 4.5 9.8 1.1
[225]
ref_hepatocyte RETSAT
Mean 21.4
Standard deviation 12
Values 8.2 25 31 9.4 34
[226]
HepG2 RETSAT
Mean 42.3
Standard deviation 4.2
Values 45 39
[227]
HepG2.C3A RETSAT
Mean 58.7
Standard deviation 23
Values 75 42
[228]
HuH.7 RETSAT
Mean 25.6
Standard deviation 4
Values 25 30 22
[229]
SNU475 RETSAT
Mean 21.5
Standard deviation 4
Values 19 24
[230]
THLE RETSAT
Mean 16
Standard deviation 1
Values 15 17
[231]
liver RETSAT
Mean 41.1
Standard deviation 19
Values 56 27 22 59
[232]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 5.9 18 0 72
[233]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[234]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.098 0.6 0.2
[236]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[237]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[238]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 92 65 1.3e+02 38
[239]
ref_hepatocyte UGT1A9
Mean 15.2
Standard deviation 13
Values 0 21 26 2.6 27
[240]
HepG2 UGT1A9
Mean 0.16
Standard deviation 0.057
Values 0.2 0.12
[241]
HepG2.C3A UGT1A9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[242]
HuH.7 UGT1A9
Mean 0.0656
Standard deviation 0.056
Values 0.066 0.12 0.0094
[243]
SNU475 UGT1A9
Mean 0.273
Standard deviation 0.34
Values 0.51 0.03
[244]
THLE UGT1A9
Mean 0.00798
Standard deviation 0.011
Values 0 0.016
[245]
liver UGT1A9
Mean 13.9
Standard deviation 9.6
Values 22 8.7 22 3
[246]
ref_hepatocyte CYP2A7
Mean 15.1
Standard deviation 22
Values 0 0.06 52 11 12
[247]
HepG2 CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[248]
HepG2.C3A CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[249]
HuH.7 CYP2A7
Mean 0.663
Standard deviation 0.76
Values 0.16 1.5 0.3
[250]
SNU475 CYP2A7
Mean 0.00739
Standard deviation 0.0039
Values 0.0046 0.01
[251]
THLE CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[252]
liver CYP2A7
Mean 6.31
Standard deviation 5.5
Values 13 2 9 1.4
[253]
ref_hepatocyte DHRS9
Mean 11.8
Standard deviation 22
Values 0 8.5 0.39 50 0.55
[254]
HepG2 DHRS9
Mean 0.0708
Standard deviation 0.052
Values 0.034 0.11
[255]
HepG2.C3A DHRS9
Mean 0.0555
Standard deviation 0.018
Values 0.068 0.043
[256]
HuH.7 DHRS9
Mean 0.0218
Standard deviation 0.015
Values 0.0082 0.039 0.019
[257]
SNU475 DHRS9
Mean 0.342
Standard deviation 0.33
Values 0.11 0.58
[258]
THLE DHRS9
Mean 0.514
Standard deviation 0.043
Values 0.54 0.48
[259]
liver DHRS9
Mean 0.291
Standard deviation 0.14
Values 0.3 0.16 0.49 0.21
[260]
ref_hepatocyte UGT2B17
Mean 10.8
Standard deviation 16
Values 0 1.3 15 1.3 37
[261]
HepG2 UGT2B17
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[262]
HepG2.C3A UGT2B17
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[263]
HuH.7 UGT2B17
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[264]
SNU475 UGT2B17
Mean 0
Standard deviation 0
Values 0 0
[265]
THLE UGT2B17
Mean 0
Standard deviation 0
Values 0 0
[266]
liver UGT2B17
Mean 6
Standard deviation 4.8
Values 8.6 3.7 11 0.5
[267]
ref_hepatocyte UGT2A3
Mean 7.91
Standard deviation 6.4
Values 18 5.7 9.3 0.33 6.3
[268]
HepG2 UGT2A3
Mean 42.4
Standard deviation 14
Values 33 52
[269]
HepG2.C3A UGT2A3
Mean 137
Standard deviation 28
Values 1.2e+02 1.6e+02
[270]
HuH.7 UGT2A3
Mean 0.775
Standard deviation 0.72
Values 0.33 1.6 0.39
[271]
SNU475 UGT2A3
Mean 0.11
Standard deviation 0.13
Values 0.2 0.02
[272]
THLE UGT2A3
Mean 0.0172
Standard deviation 0.0092
Values 0.024 0.011
[273]
liver UGT2A3
Mean 31.9
Standard deviation 15
Values 24 55 25 24
[274]
ref_hepatocyte RDH10
Mean 6.75
Standard deviation 3.6
Values 7.6 3.6 9.8 2.3 10
[275]
HepG2 RDH10
Mean 16.3
Standard deviation 4.8
Values 20 13
[276]
HepG2.C3A RDH10
Mean 23.6
Standard deviation 3.5
Values 26 21
[277]
HuH.7 RDH10
Mean 10.9
Standard deviation 1.6
Values 9.1 12 12
[278]
SNU475 RDH10
Mean 16.9
Standard deviation 5
Values 20 13
[279]
THLE RDH10
Mean 7.13
Standard deviation 1.4
Values 6.1 8.1
[280]
liver RDH10
Mean 19.3
Standard deviation 7.3
Values 22 22 8.6 25
[281]
ref_hepatocyte DGAT1
Mean 6.41
Standard deviation 5.1
Values 11 1.1 10 0.65 9.5
[282]
HepG2 DGAT1
Mean 35.1
Standard deviation 15
Values 25 46
[283]
HepG2.C3A DGAT1
Mean 27.7
Standard deviation 5.1
Values 31 24
[284]
HuH.7 DGAT1
Mean 37.4
Standard deviation 7
Values 39 30 43
[285]
SNU475 DGAT1
Mean 9.37
Standard deviation 0.38
Values 9.1 9.6
[286]
THLE DGAT1
Mean 9.47
Standard deviation 1.3
Values 10 8.5
[287]
liver DGAT1
Mean 10.5
Standard deviation 4.6
Values 6.7 16 13 6.4
[288]
ref_hepatocyte UGT1A3
Mean 4.24
Standard deviation 4.8
Values 0 2.3 7.9 0.37 11
[289]
HepG2 UGT1A3
Mean 1.2
Standard deviation 0.2
Values 1.3 1.1
[290]
HepG2.C3A UGT1A3
Mean 0
Standard deviation 0
Values 0 0
[291]
HuH.7 UGT1A3
Mean 0.0101
Standard deviation 0.0024
Values 0.0082 0.013 0.0094
[292]
SNU475 UGT1A3
Mean 0.0911
Standard deviation 0.029
Values 0.11 0.071
[293]
THLE UGT1A3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[294]
liver UGT1A3
Mean 14.2
Standard deviation 12
Values 21 2.5 28 5.8
[295]
ref_hepatocyte PNPLA4
Mean 4.18
Standard deviation 1.9
Values 2.1 2.5 6.6 4.4 5.3
[296]
HepG2 PNPLA4
Mean 8.31
Standard deviation 1.6
Values 9.4 7.2
[297]
HepG2.C3A PNPLA4
Mean 7.39
Standard deviation 0.28
Values 7.2 7.6
[298]
HuH.7 PNPLA4
Mean 7.76
Standard deviation 1.5
Values 8 6.2 9.1
[299]
SNU475 PNPLA4
Mean 3.61
Standard deviation 0.72
Values 4.1 3.1
[300]
THLE PNPLA4
Mean 10.2
Standard deviation 1.8
Values 8.9 11
[301]
liver PNPLA4
Mean 7.93
Standard deviation 4.8
Values 3.1 14 9.7 5
[302]
ref_hepatocyte CYP4A22
Mean 3.13
Standard deviation 4
Values 0 0.14 7.2 0.49 7.8
[303]
HepG2 CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[304]
HepG2.C3A CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[305]
HuH.7 CYP4A22
Mean 0
Standard deviation 0
Values 0 0 0
[306]
SNU475 CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[307]
THLE CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[308]
liver CYP4A22
Mean 21.4
Standard deviation 17
Values 6.3 46 15 18
[309]
ref_hepatocyte CYP3A43
Mean 1.46
Standard deviation 2.7
Values 0.059 0 1.1 0 6.1
[310]
HepG2 CYP3A43
Mean 0.112
Standard deviation 0.061
Values 0.069 0.15
[311]
HepG2.C3A CYP3A43
Mean 0.735
Standard deviation 0.42
Values 1 0.44
[312]
HuH.7 CYP3A43
Mean 0.622
Standard deviation 0.91
Values 0.057 1.7 0.14
[313]
SNU475 CYP3A43
Mean 0
Standard deviation 0
Values 0 0
[314]
THLE CYP3A43
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[315]
liver CYP3A43
Mean 5.41
Standard deviation 4.2
Values 2.9 12 3.4 3.6
[316]
ref_hepatocyte RDH12
Mean 0.661
Standard deviation 0.71
Values 0.31 0.065 1.8 0.22 0.9
[317]
HepG2 RDH12
Mean 0.626
Standard deviation 0.27
Values 0.82 0.43
[318]
HepG2.C3A RDH12
Mean 2.47
Standard deviation 0.33
Values 2.7 2.2
[319]
HuH.7 RDH12
Mean 0.0216
Standard deviation 0.015
Values 0.0082 0.019 0.037
[320]
SNU475 RDH12
Mean 0.05
Standard deviation 0.051
Values 0.014 0.086
[321]
THLE RDH12
Mean 0.0692
Standard deviation 0.023
Values 0.053 0.085
[322]
liver RDH12
Mean 1.2
Standard deviation 1.2
Values 1 0.63 2.9 0.19
[323]
ref_hepatocyte UGT1A5
Mean 0.393
Standard deviation 0.32
Values 0 0.38 0.82 0.19 0.58
[324]
HepG2 UGT1A5
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[325]
HepG2.C3A UGT1A5
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 UGT1A5
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[327]
SNU475 UGT1A5
Mean 0.0747
Standard deviation 0.012
Values 0.083 0.066
[328]
THLE UGT1A5
Mean 0
Standard deviation 0
Values 0 0
[329]
liver UGT1A5
Mean 1.38
Standard deviation 1.4
Values 3.4 0.31 0.98 0.85
[330]
ref_hepatocyte UGT2B11
Mean 0.391
Standard deviation 0.65
Values 0 0 1.5 0 0.46
[331]
HepG2 UGT2B11
Mean 1
Standard deviation 0.2
Values 0.86 1.1
[332]
HepG2.C3A UGT2B11
Mean 0.348
Standard deviation 0.19
Values 0.21 0.48
[333]
HuH.7 UGT2B11
Mean 0.795
Standard deviation 0.79
Values 0.31 1.7 0.37
[334]
SNU475 UGT2B11
Mean 0.00928
Standard deviation 0.013
Values 0.019 0
[335]
THLE UGT2B11
Mean 0
Standard deviation 0
Values 0 0
[336]
liver UGT2B11
Mean 0.98
Standard deviation 0.68
Values 0.59 2 0.49 0.87
[337]
ref_hepatocyte UGT2B28
Mean 0.294
Standard deviation 0.52
Values 0 0 0.28 0 1.2
[338]
HepG2 UGT2B28
Mean 0.642
Standard deviation 0.23
Values 0.81 0.48
[339]
HepG2.C3A UGT2B28
Mean 0.816
Standard deviation 0.45
Values 0.5 1.1
[340]
HuH.7 UGT2B28
Mean 0.0413
Standard deviation 0.043
Values 0.025 0.09 0.0094
[341]
SNU475 UGT2B28
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[342]
THLE UGT2B28
Mean 0
Standard deviation 0
Values 0 0
[343]
liver UGT2B28
Mean 0.714
Standard deviation 0.87
Values 1.1 0 1.8 0.013
[344]
ref_hepatocyte CYP26A1
Mean 0.247
Standard deviation 0.38
Values 0 0 0.86 0 0.37
[345]
HepG2 CYP26A1
Mean 4.9
Standard deviation 3.4
Values 7.3 2.5
[346]
HepG2.C3A CYP26A1
Mean 0.0764
Standard deviation 0.0019
Values 0.078 0.075
[347]
HuH.7 CYP26A1
Mean 0.853
Standard deviation 0.36
Values 0.55 1.3 0.76
[348]
SNU475 CYP26A1
Mean 0.504
Standard deviation 0.37
Values 0.77 0.24
[349]
THLE CYP26A1
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[350]
liver CYP26A1
Mean 0.705
Standard deviation 0.82
Values 0.74 0.19 1.8 0.04
[351]
ref_hepatocyte ALDH1A2
Mean 0.153
Standard deviation 0.15
Values 0 0.075 0.086 0.37 0.24
[352]
HepG2 ALDH1A2
Mean 0.0222
Standard deviation 0.025
Values 0.04 0.0043
[353]
HepG2.C3A ALDH1A2
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[354]
HuH.7 ALDH1A2
Mean 0.211
Standard deviation 0.19
Values 0.09 0.43 0.11
[355]
SNU475 ALDH1A2
Mean 0.162
Standard deviation 0.0069
Values 0.17 0.16
[356]
THLE ALDH1A2
Mean 34.9
Standard deviation 6.3
Values 30 39
[357]
liver ALDH1A2
Mean 1
Standard deviation 0.59
Values 1.1 0.47 0.64 1.8
[358]
ref_hepatocyte LRAT
Mean 0.0892
Standard deviation 0.057
Values 0.14 0.12 0.12 0.052 0.0081
[359]
HepG2 LRAT
Mean 0.0608
Standard deviation 0.005
Values 0.057 0.064
[360]
HepG2.C3A LRAT
Mean 0.0803
Standard deviation 0.038
Values 0.11 0.054
[361]
HuH.7 LRAT
Mean 0.0332
Standard deviation 0.029
Values 0.0082 0.026 0.066
[362]
SNU475 LRAT
Mean 0.0606
Standard deviation 0.00038
Values 0.06 0.061
[363]
THLE LRAT
Mean 0.103
Standard deviation 0.055
Values 0.14 0.064
[364]
liver LRAT
Mean 4.65
Standard deviation 3.2
Values 2.5 9.2 4.5 2.4
[365]
ref_hepatocyte CYP2A13
Mean 0.0683
Standard deviation 0.12
Values 0 0 0.28 0 0.057
[366]
HepG2 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[367]
HepG2.C3A CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[368]
HuH.7 CYP2A13
Mean 0
Standard deviation 0
Values 0 0 0
[369]
SNU475 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[370]
THLE CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[371]
liver CYP2A13
Mean 0.0677
Standard deviation 0.059
Values 0.13 0 0.1 0.04
[372]
ref_hepatocyte UGT1A7
Mean 0.0431
Standard deviation 0.096
Values 0 0 0.22 0 0
[373]
HepG2 UGT1A7
Mean 0.0537
Standard deviation 0.021
Values 0.069 0.039
[374]
HepG2.C3A UGT1A7
Mean 0
Standard deviation 0
Values 0 0
[375]
HuH.7 UGT1A7
Mean 0.0277
Standard deviation 0.011
Values 0.016 0.039 0.028
[376]
SNU475 UGT1A7
Mean 2.06
Standard deviation 1.2
Values 1.2 2.9
[377]
THLE UGT1A7
Mean 0.0556
Standard deviation 0.012
Values 0.047 0.064
[378]
liver UGT1A7
Mean 0.582
Standard deviation 0.83
Values 1.8 0.094 0.1 0.32
[379]
ref_hepatocyte ADH7
Mean 0.0374
Standard deviation 0.084
Values 0 0 0 0 0.19
[380]
HepG2 ADH7
Mean 0
Standard deviation 0
Values 0 0
[381]
HepG2.C3A ADH7
Mean 0
Standard deviation 0
Values 0 0
[382]
HuH.7 ADH7
Mean 0
Standard deviation 0
Values 0 0 0
[383]
SNU475 ADH7
Mean 0
Standard deviation 0
Values 0 0
[384]
THLE ADH7
Mean 0
Standard deviation 0
Values 0 0
[385]
liver ADH7
Mean 0.00662
Standard deviation 0.013
Values 0 0 0 0.026
[386]
ref_hepatocyte CYP26B1
Mean 0.0121
Standard deviation 0.027
Values 0 0 0.06 0 0
[387]
HepG2 CYP26B1
Mean 0.791
Standard deviation 0.35
Values 1 0.54
[388]
HepG2.C3A CYP26B1
Mean 0.0848
Standard deviation 0.092
Values 0.019 0.15
[389]
HuH.7 CYP26B1
Mean 12
Standard deviation 3.7
Values 14 7.7 14
[390]
SNU475 CYP26B1
Mean 2.31
Standard deviation 2.1
Values 0.84 3.8
[391]
THLE CYP26B1
Mean 1.52
Standard deviation 0.59
Values 1.9 1.1
[392]
liver CYP26B1
Mean 0.794
Standard deviation 0.48
Values 0.43 0.78 0.49 1.5
[393]
ref_hepatocyte UGT1A10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[394]
HepG2 UGT1A10
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[395]
HepG2.C3A UGT1A10
Mean 0
Standard deviation 0
Values 0 0
[396]
HuH.7 UGT1A10
Mean 0.115
Standard deviation 0.078
Values 0.066 0.21 0.075
[397]
SNU475 UGT1A10
Mean 0.012
Standard deviation 0.0027
Values 0.014 0.01
[398]
THLE UGT1A10
Mean 0
Standard deviation 0
Values 0 0
[399]
liver UGT1A10
Mean 0.0104
Standard deviation 0.014
Values 0.029 0 0 0.013
[400]
ref_hepatocyte UGT1A8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[401]
HepG2 UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[402]
HepG2.C3A UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[403]
HuH.7 UGT1A8
Mean 0.0407
Standard deviation 0.027
Values 0.033 0.071 0.019
[404]
SNU475 UGT1A8
Mean 0.152
Standard deviation 0.028
Values 0.17 0.13
[405]
THLE UGT1A8
Mean 0
Standard deviation 0
Values 0 0
[406]
liver UGT1A8
Mean 0.0104
Standard deviation 0.014
Values 0.029 0 0 0.013
[407]
ref_hepatocyte AWAT2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[408]
HepG2 AWAT2
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[409]
HepG2.C3A AWAT2
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[410]
HuH.7 AWAT2
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[411]
SNU475 AWAT2
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[412]
THLE AWAT2
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[413]
liver AWAT2
Mean 0
Standard deviation 0
Values 0 0 0 0
[414]
ref_hepatocyte CYP26C1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[415]
HepG2 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[416]
HepG2.C3A CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[417]
HuH.7 CYP26C1
Mean 0.176
Standard deviation 0.084
Values 0.26 0.17 0.094
[418]
SNU475 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[419]
THLE CYP26C1
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[420]
liver CYP26C1
Mean 0.0165
Standard deviation 0.033
Values 0 0 0 0.066
[421]
ref_hepatocyte RPE65
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[422]
HepG2 RPE65
Mean 0.0258
Standard deviation 0.012
Values 0.017 0.034
[423]
HepG2.C3A RPE65
Mean 0
Standard deviation 0
Values 0 0
[424]
HuH.7 RPE65
Mean 0
Standard deviation 0
Values 0 0 0
[425]
SNU475 RPE65
Mean 0
Standard deviation 0
Values 0 0
[426]
THLE RPE65
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[427]
liver RPE65
Mean 0
Standard deviation 0
Values 0 0 0 0
[428]
ref_hepatocyte BCO1
Missing
[429]
HepG2 BCO1
Missing
[430]
HepG2.C3A BCO1
Missing
[431]
HuH.7 BCO1
Missing
[432]
SNU475 BCO1
Missing
[433]
THLE BCO1
Missing
[434]
liver BCO1
Missing
[435]
ref_hepatocyte UGT2A1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[436]
HepG2 UGT2A1
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[437]
HepG2.C3A UGT2A1
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[438]
HuH.7 UGT2A1
Mean 0
Standard deviation 0
Values 0 0 0
[439]
SNU475 UGT2A1
Mean 0.015
Standard deviation 0.015
Values 0.0046 0.025
[440]
THLE UGT2A1
Mean 0
Standard deviation 0
Values 0 0
[441]
liver UGT2A1
Mean 0.00999
Standard deviation 0.012
Values 0.014 0 0.026 0
[442]
ref_hepatocyte RDH8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[443]
HepG2 RDH8
Mean 0
Standard deviation 0
Values 0 0
[444]
HepG2.C3A RDH8
Mean 0
Standard deviation 0
Values 0 0
[445]
HuH.7 RDH8
Mean 0.0138
Standard deviation 0.017
Values 0 0.032 0.0094
[446]
SNU475 RDH8
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[447]
THLE RDH8
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[448]
liver RDH8
Mean 0
Standard deviation 0
Values 0 0 0 0