KEGG_RENAL_CELL_CARCINOMA | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CDC42 | Cell division control protein 42 homolog | [1] | -1.24[2] | -0.35[3] | -1.37[4] | -0.93[5] | -1.67[6] | -2.13[7] |
2 | RAP1B | Ras-related protein Rap-1b | [8] | -2.72[9] | -1.93[10] | -2.17[11] | -0.92[12] | -1.19[13] | -1.93[14] |
3 | RBX1 | E3 ubiquitin-protein ligase RBX1 | [15] | -2.47[16] | -1.86[17] | -2.00[18] | -3.10[19] | -2.69[20] | -2.14[21] |
4 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [22] | -0.81[23] | -0.96[24] | -0.27[25] | -0.38[26] | -0.42[27] | -1.01[28] |
5 | FH | Fumarate hydratase, mitochondrial | [29] | -1.99[30] | -1.58[31] | -1.39[32] | -1.22[33] | -1.75[34] | 0.09[35] |
6 | JUN | Transcription factor AP-1 | [36] | -0.90[37] | -2.27[38] | -2.02[39] | -2.10[40] | -1.55[41] | -1.85[42] |
7 | AKT1 | RAC-alpha serine/threonine-protein kinase | [43] | -0.33[44] | -0.39[45] | -1.49[46] | -0.44[47] | -0.44[48] | -0.29[49] |
8 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [50] | -1.34[51] | -1.50[52] | -0.93[53] | -0.94[54] | -0.45[55] | -1.24[56] |
9 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [57] | -0.36[58] | -0.51[59] | 0.35[60] | -1.24[61] | -0.77[62] | -1.75[63] |
10 | HIF1A | Hypoxia-inducible factor 1-alpha | [64] | -0.57[65] | -0.72[66] | 0.06[67] | 1.89[68] | 2.25[69] | -0.85[70] |
11 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [71] | 0.03[72] | 0.64[73] | 0.58[74] | 0.50[75] | 1.11[76] | 1.21[77] |
12 | GRB2 | Growth factor receptor-bound protein 2 | [78] | 0.78[79] | 0.79[80] | 0.90[81] | 0.16[82] | 0.05[83] | 0.25[84] |
13 | CRK | Adapter molecule crk | [85] | -0.62[86] | -0.51[87] | -0.46[88] | -0.63[89] | -0.26[90] | 0.80[91] |
14 | RAP1A | Ras-related protein Rap-1A | [92] | -1.46[93] | -1.35[94] | -0.53[95] | -0.61[96] | -0.87[97] | -1.33[98] |
15 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [99] | -0.48[100] | 0.10[101] | 1.35[102] | -0.58[103] | 0.26[104] | 1.05[105] |
16 | VEGFA | Vascular endothelial growth factor A | [106] | 0.80[107] | 2.32[108] | 0.90[109] | 0.05[110] | 0.73[111] | 0.74[112] |
17 | NRAS | GTPase NRas | [113] | 0.21[114] | 0.82[115] | 1.22[116] | 0.60[117] | 0.15[118] | -0.29[119] |
18 | EGLN2 | Egl nine homolog 2 | [120] | -5.80[121] | -5.93[122] | -5.15[123] | -5.64[124] | -5.30[125] | -6.50[126] |
19 | MET | Hepatocyte growth factor receptor | [127] | -0.33[128] | -0.12[129] | 0.49[130] | 1.14[131] | -0.16[132] | 0.93[133] |
20 | EPAS1 | Endothelial PAS domain-containing protein 1 | [134] | 2.29[135] | 1.68[136] | 1.32[137] | -0.96[138] | 2.03[139] | 1.88[140] |
21 | ARAF | Serine/threonine-protein kinase A-Raf | [141] | -0.87[142] | -1.00[143] | -0.75[144] | -0.49[145] | -0.48[146] | 0.83[147] |
22 | HRAS | GTPase HRas | [148] | -1.42[149] | -1.95[150] | -2.76[151] | -1.34[152] | -1.58[153] | -2.70[154] |
23 | ETS1 | Protein C-ets-1 | [155] | -3.22[156] | -12.38[157] | -9.60[158] | -0.49[159] | 0.34[160] | -0.13[161] |
24 | PAK2 | Serine/threonine-protein kinase PAK 2 | [162] | 1.03[163] | 0.96[164] | 1.23[165] | 0.36[166] | 0.88[167] | 1.32[168] |
25 | MAPK1 | Mitogen-activated protein kinase 1 | [169] | 1.29[170] | 1.61[171] | 1.42[172] | 1.46[173] | 1.08[174] | 1.73[175] |
26 | AKT2 | RAC-beta serine/threonine-protein kinase | [176] | 0.54[177] | 1.00[178] | 1.11[179] | 0.46[180] | 0.23[181] | 1.09[182] |
27 | KRAS | GTPase KRas | [183] | -0.93[184] | -0.77[185] | 0.81[186] | 0.41[187] | 0.04[188] | 0.63[189] |
28 | EGLN1 | Egl nine homolog 1 | [190] | 0.91[191] | 0.74[192] | 0.21[193] | 1.08[194] | 1.02[195] | 1.46[196] |
29 | CRKL | Crk-like protein | [197] | 1.29[198] | 1.56[199] | 2.15[200] | 0.73[201] | 0.91[202] | 1.41[203] |
30 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [204] | -0.89[205] | -0.59[206] | 0.48[207] | 1.67[208] | 1.15[209] | 2.96[210] |
31 | SOS1 | Son of sevenless homolog 1 | [211] | -0.52[212] | 1.19[213] | 0.68[214] | 0.45[215] | -0.34[216] | 0.49[217] |
32 | ARNT | Aryl hydrocarbon receptor nuclear translocator | [218] | 0.00[219] | -0.03[220] | 0.82[221] | 0.97[222] | 0.72[223] | 1.49[224] |
33 | FLCN | Folliculin | [225] | 0.13[226] | -0.60[227] | 1.04[228] | 0.40[229] | -0.21[230] | 0.72[231] |
34 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [232] | 1.46[233] | 1.86[234] | 2.45[235] | 0.31[236] | 0.85[237] | -0.33[238] |
35 | VHL | von Hippel-Lindau disease tumor suppressor | [239] | 1.53[240] | 1.83[241] | 2.59[242] | 0.45[243] | 1.11[244] | 0.93[245] |
36 | VEGFB | Vascular endothelial growth factor B | [246] | -0.47[247] | -0.47[248] | -0.46[249] | 0.36[250] | 0.03[251] | -1.76[252] |
37 | RAPGEF1 | Rap guanine nucleotide exchange factor 1 | [253] | 1.67[254] | 1.68[255] | 1.38[256] | 0.86[257] | 0.51[258] | 1.13[259] |
38 | CUL2 | Cullin-2 | [260] | -0.32[261] | 1.28[262] | 1.42[263] | 2.06[264] | 1.40[265] | 0.96[266] |
39 | PAK4 | Serine/threonine-protein kinase PAK 4 | [267] | 0.48[268] | 0.70[269] | 1.37[270] | 0.63[271] | 0.33[272] | -0.37[273] |
40 | MAPK3 | Mitogen-activated protein kinase 3 | [274] | 1.43[275] | 1.66[276] | 1.68[277] | 0.03[278] | 0.03[279] | -1.08[280] |
41 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.80[281] | 1.48[282] | 1.62[283] | 0.66[284] | 0.79[285] | 1.11[286] | |
42 | TGFB2 | Transforming growth factor beta-2 | [287] | -4.71[288] | -7.06[289] | -1.27[290] | 3.07[291] | 1.64[292] | -2.81[293] |
43 | SOS2 | Son of sevenless homolog 2 | [294] | -0.44[295] | 0.86[296] | 0.07[297] | 1.30[298] | 1.14[299] | 1.80[300] |
44 | EP300 | Histone acetyltransferase p300 | [301] | 2.31[302] | 2.08[303] | 2.95[304] | 2.18[305] | 2.21[306] | 2.71[307] |
45 | PAK1 | Serine/threonine-protein kinase PAK 1 | [308] | -0.43[309] | -1.01[310] | 1.38[311] | -2.25[312] | 1.51[313] | 0.22[314] |
46 | SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1 | [315] | 6.23[316] | 3.42[317] | 2.47[318] | 3.05[319] | 2.16[320] | -1.39[321] |
47 | TGFB1 | Transforming growth factor beta-1 | [322] | 3.06[323] | 2.19[324] | -0.57[325] | 3.44[326] | 2.65[327] | -1.27[328] |
48 | TGFA | Protransforming growth factor alpha | [329] | 1.38[330] | 2.62[331] | -8.45[332] | -1.35[333] | -2.60[334] | -0.44[335] |
49 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.80[336] | 1.02[337] | 1.19[338] | 0.74[339] | 0.92[340] | 1.87[341] | |
50 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 1.47[342] | 2.74[343] | -1.09[344] | -0.11[345] | 0.63[346] | 0.25[347] | |
51 | CREBBP | CREB-binding protein | [348] | 2.48[349] | 1.88[350] | 2.47[351] | 2.36[352] | 2.35[353] | 3.19[354] |
52 | TGFB3 | Transforming growth factor beta-3 | [355] | -1.96[356] | -2.66[357] | -2.91[358] | -0.22[359] | -1.31[360] | 0.41[361] |
53 | EGLN3 | Egl nine homolog 3 | [362] | 2.72[363] | 1.77[364] | 0.98[365] | 2.55[366] | -1.07[367] | -0.63[368] |
54 | BRAF | Serine/threonine-protein kinase B-raf | [369] | -0.17[370] | -0.26[371] | 1.75[372] | 0.35[373] | 0.02[374] | 1.81[375] |
55 | PGF | Placenta growth factor | [376] | 1.17[377] | 2.11[378] | 1.90[379] | -1.52[380] | 0.14[381] | -0.67[382] |
56 | GAB1 | GRB2-associated-binding protein 1 | [383] | 0.89[384] | 2.15[385] | 2.26[386] | 1.54[387] | 1.38[388] | 2.83[389] |
57 | PDGFB | Platelet-derived growth factor subunit B | [390] | 2.64[391] | 2.68[392] | -0.15[393] | -0.33[394] | -0.78[395] | 0.33[396] |
58 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [397] | 1.31[398] | 1.49[399] | 2.32[400] | 2.77[401] | 1.77[402] | 2.63[403] |
59 | AKT3 | RAC-gamma serine/threonine-protein kinase | [404] | -2.26[405] | -4.64[406] | -3.97[407] | 5.45[408] | 4.38[409] | 3.56[410] |
60 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | [411] | -7.58[412] | [413] | -2.79[414] | -4.32[415] | -4.00[416] | 2.29[417] |
61 | PAK3 | Serine/threonine-protein kinase PAK 3 | [418] | -6.83[419] | [420] | [421] | -1.99[422] | -0.30[423] | 0.74[424] |
62 | PAK6 | Serine/threonine-protein kinase PAK 6 | [425] | -2.09[426] | [427] | 0.80[428] | 1.81[429] | 0.90[430] | -1.12[431] |
63 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [432] | [433] | [434] | 0.95[435] | -3.96[436] | 4.05[437] | |
64 | VEGFC | Vascular endothelial growth factor C | [438] | -0.85[439] | -3.77[440] | -4.70[441] | 3.22[442] | 6.83[443] | 3.24[444] |
65 | HGF | Hepatocyte growth factor | [445] | [446] | [447] | -1.90[448] | 4.20[449] | 1.21[450] | 8.85[451] |
66 | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2 | [452] | 4.97[453] | -2.86[454] | -1.55[455] | 6.03[456] | 7.77[457] | 4.90[458] |
67 | ELOB | Elongin-B | [459] | [460] | [461] | [462] | [463] | [464] | [465] |
68 | PAK5 | Serine/threonine-protein kinase PAK 5 | [466] | [467] | [468] | [469] | [470] | [471] | [472] |
69 | VEGFD | Vascular endothelial growth factor D | [473] | [474] | [475] | [476] | [477] | [478] | [479] |
70 | ELOC | Elongin-C | [480] | [481] | [482] | [483] | [484] | [485] | [486] |