KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSP90AB1 | Heat shock protein HSP 90-beta | [1] | 0.13[2] | -0.15[3] | -0.53[4] | -0.63[5] | -1.20[6] | -1.54[7] |
2 | HSP90AA1 | Heat shock protein HSP 90-alpha | [8] | -0.75[9] | -0.15[10] | -0.49[11] | 0.01[12] | -0.26[13] | -0.70[14] |
3 | ANAPC11 | Anaphase-promoting complex subunit 11 | [15] | -1.94[16] | -1.86[17] | -1.86[18] | -2.40[19] | -1.97[20] | -0.84[21] |
4 | AKT1 | RAC-alpha serine/threonine-protein kinase | [22] | -0.02[23] | -0.63[24] | -1.28[25] | -0.13[26] | -0.06[27] | 0.31[28] |
5 | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | [29] | -0.04[30] | -1.47[31] | -0.88[32] | -0.25[33] | 0.87[34] | 0.36[35] |
6 | CDC26 | Anaphase-promoting complex subunit CDC26 | [36] | -2.88[37] | -2.77[38] | -2.38[39] | -3.11[40] | -2.17[41] | -1.65[42] |
7 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [43] | -1.03[44] | -1.73[45] | -0.73[46] | -0.62[47] | -0.07[48] | -0.63[49] |
8 | MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B | [50] | -1.64[51] | -0.59[52] | -1.44[53] | -1.75[54] | -1.49[55] | -0.86[56] |
9 | ANAPC13 | Anaphase-promoting complex subunit 13 | [57] | -0.93[58] | -0.85[59] | -0.45[60] | -0.95[61] | -0.87[62] | 0.39[63] |
10 | ANAPC5 | Anaphase-promoting complex subunit 5 | [64] | 0.77[65] | 1.07[66] | 1.65[67] | 0.25[68] | 0.76[69] | 1.27[70] |
11 | IGF1 | Insulin-like growth factor I | [71] | -8.52[72] | -9.83[73] | -7.62[74] | -1.62[75] | -9.40[76] | 1.48[77] |
12 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [78] | -0.27[79] | -0.81[80] | -0.39[81] | -0.55[82] | 0.09[83] | -0.22[84] |
13 | GNAI3 | Guanine nucleotide-binding protein G(k) subunit alpha | [85] | 0.02[86] | 0.20[87] | 0.72[88] | 1.02[89] | 0.70[90] | 0.79[91] |
14 | RAF1 | RAF proto-oncogene serine/threonine-protein kinase | [92] | -0.17[93] | -0.13[94] | 1.56[95] | -0.27[96] | 0.65[97] | 1.65[98] |
15 | CDC27 | Cell division cycle protein 27 homolog | [99] | 0.11[100] | 0.58[101] | 0.36[102] | 1.10[103] | 0.69[104] | 0.71[105] |
16 | CDC16 | Cell division cycle protein 16 homolog | [106] | -0.60[107] | -0.74[108] | -0.97[109] | -0.50[110] | -0.01[111] | 0.43[112] |
17 | ARAF | Serine/threonine-protein kinase A-Raf | [113] | -0.56[114] | -1.24[115] | -0.54[116] | -0.18[117] | -0.10[118] | 1.43[119] |
18 | CDK2 | Cyclin-dependent kinase 2 | [120] | -0.52[121] | -0.72[122] | 0.08[123] | -0.10[124] | 0.54[125] | -1.63[126] |
19 | MAPK1 | Mitogen-activated protein kinase 1 | [127] | 1.61[128] | 1.37[129] | 1.63[130] | 1.77[131] | 1.46[132] | 2.33[133] |
20 | AKT2 | RAC-beta serine/threonine-protein kinase | [134] | 0.86[135] | 0.76[136] | 1.32[137] | 0.78[138] | 0.62[139] | 1.69[140] |
21 | RPS6KA3 | Ribosomal protein S6 kinase alpha-3 | [141] | [142] | [143] | [144] | [145] | [146] | [147] |
22 | KRAS | GTPase KRas | [148] | -0.62[149] | -1.01[150] | 1.02[151] | 0.72[152] | 0.43[153] | 1.23[154] |
23 | MAPK14 | Mitogen-activated protein kinase 14 | [155] | 1.37[156] | 1.07[157] | 1.07[158] | 1.60[159] | 1.12[160] | 1.84[161] |
24 | MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A | [162] | 0.49[163] | 1.25[164] | 1.00[165] | -0.03[166] | 1.13[167] | -2.32[168] |
25 | CCNB1 | G2/mitotic-specific cyclin-B1 | [169] | 1.74[170] | 1.61[171] | 2.21[172] | 1.52[173] | 2.55[174] | -1.79[175] |
26 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [176] | -0.57[177] | -0.83[178] | 0.69[179] | 1.99[180] | 1.53[181] | 3.56[182] |
27 | CDC23 | Cell division cycle protein 23 homolog | [183] | 0.27[184] | 0.10[185] | 0.79[186] | 0.95[187] | 0.71[188] | 0.75[189] |
28 | MAPK8 | Mitogen-activated protein kinase 8 | [190] | -1.55[191] | -0.51[192] | -1.21[193] | -0.98[194] | -1.08[195] | 0.05[196] |
29 | GNAI1 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | [197] | -1.75[198] | -3.06[199] | -0.50[200] | 1.13[201] | 0.55[202] | 1.39[203] |
30 | FZR1 | Fizzy-related protein homolog | [204] | 0.65[205] | -0.08[206] | 0.43[207] | -0.05[208] | 0.59[209] | 1.18[210] |
31 | CDK1 | Cyclin-dependent kinase 1 | [211] | 1.15[212] | 2.84[213] | 2.00[214] | 2.19[215] | 3.05[216] | -1.91[217] |
32 | ANAPC7 | Anaphase-promoting complex subunit 7 | [218] | 0.90[219] | 0.93[220] | 0.83[221] | 0.82[222] | 1.12[223] | 0.74[224] |
33 | ANAPC2 | Anaphase-promoting complex subunit 2 | [225] | 0.50[226] | -0.43[227] | 0.61[228] | -0.04[229] | -0.03[230] | 0.60[231] |
34 | MAPK13 | Mitogen-activated protein kinase 13 | [232] | 2.24[233] | 2.27[234] | 0.02[235] | -1.97[236] | -0.40[237] | -1.16[238] |
35 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [239] | 1.77[240] | 1.62[241] | 2.66[242] | 0.63[243] | 1.23[244] | 0.27[245] |
36 | PLK1 | Serine/threonine-protein kinase PLK1 | [246] | 2.39[247] | 1.76[248] | 2.04[249] | 1.16[250] | 2.25[251] | -2.07[252] |
37 | RPS6KA1 | Ribosomal protein S6 kinase alpha-1 | [253] | [254] | [255] | [256] | [257] | [258] | [259] |
38 | MAPK9 | Mitogen-activated protein kinase 9 | [260] | 1.12[261] | 0.98[262] | 1.47[263] | 1.63[264] | 1.14[265] | 1.07[266] |
39 | MAPK3 | Mitogen-activated protein kinase 3 | [267] | 1.75[268] | 1.42[269] | 1.89[270] | 0.34[271] | 0.41[272] | -0.48[273] |
40 | CDC25B | M-phase inducer phosphatase 2 | [274] | 1.76[275] | 1.57[276] | 1.38[277] | 2.64[278] | 2.85[279] | 0.90[280] |
41 | ANAPC1 | Anaphase-promoting complex subunit 1 | [281] | 2.31[282] | 2.12[283] | 2.43[284] | 1.84[285] | 1.91[286] | 2.01[287] |
42 | PDE3B | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | [288] | 0.35[289] | 0.94[290] | 1.61[291] | -1.46[292] | -1.85[293] | 3.43[294] |
43 | CCNA2 | Cyclin-A2 | [295] | 2.10[296] | 2.74[297] | 2.51[298] | 1.92[299] | 3.36[300] | -0.67[301] |
44 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 1.11[302] | 1.24[303] | 1.83[304] | 0.97[305] | 1.17[306] | 1.71[307] | |
45 | PRKACB | cAMP-dependent protein kinase catalytic subunit beta | [308] | -0.94[309] | -0.53[310] | 1.18[311] | 2.15[312] | 1.06[313] | 2.27[314] |
46 | ANAPC4 | Anaphase-promoting complex subunit 4 | [315] | 0.09[316] | 0.65[317] | 1.40[318] | 1.11[319] | 0.63[320] | 1.54[321] |
47 | ADCY9 | Adenylate cyclase type 9 | [322] | 2.52[323] | 1.33[324] | 2.18[325] | 0.88[326] | 0.47[327] | 2.97[328] |
48 | ANAPC10 | Anaphase-promoting complex subunit 10 | [329] | -0.34[330] | 0.18[331] | -0.01[332] | -0.31[333] | 0.52[334] | 0.68[335] |
49 | CDC25A | M-phase inducer phosphatase 1 | [336] | 1.32[337] | 1.59[338] | 2.36[339] | 0.26[340] | 1.77[341] | -2.10[342] |
50 | CCNB2 | G2/mitotic-specific cyclin-B2 | [343] | 1.99[344] | 2.38[345] | 3.18[346] | 2.44[347] | 3.47[348] | -1.04[349] |
51 | BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1 | [350] | 2.08[351] | 2.86[352] | 2.92[353] | 3.01[354] | 3.41[355] | -0.76[356] |
52 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.48[357] | 0.78[358] | 1.40[359] | 1.05[360] | 1.30[361] | 2.47[362] | |
53 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 1.78[363] | 2.50[364] | -0.89[365] | 0.20[366] | 1.01[367] | 0.86[368] | |
54 | ADCY6 | Adenylate cyclase type 6 | [369] | 1.95[370] | 2.04[371] | 2.43[372] | 2.42[373] | 3.14[374] | 3.19[375] |
55 | PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | 1.21[376] | 0.62[377] | 1.18[378] | 0.56[379] | 1.80[380] | -2.00[381] | |
56 | RPS6KA2 | Ribosomal protein S6 kinase alpha-2 | [382] | [383] | [384] | [385] | [386] | [387] | [388] |
57 | BRAF | Serine/threonine-protein kinase B-raf | [389] | 0.15[390] | -0.50[391] | 1.96[392] | 0.66[393] | 0.40[394] | 2.41[395] |
58 | SPDYC | Speedy protein C | [396] | -1.34[397] | 0.14[398] | -6.81[399] | [400] | -9.35[401] | -2.41[402] |
59 | ADCY1 | Adenylate cyclase type 1 | [403] | -0.94[404] | -3.18[405] | -2.95[406] | -2.19[407] | -2.16[408] | 5.55[409] |
60 | IGF1R | Insulin-like growth factor 1 receptor | [410] | 4.64[411] | 3.58[412] | 2.68[413] | 4.39[414] | 3.98[415] | 2.65[416] |
61 | MAPK12 | Mitogen-activated protein kinase 12 | [417] | 2.72[418] | 2.01[419] | 3.55[420] | 1.40[421] | 2.70[422] | -0.35[423] |
62 | CDC25C | M-phase inducer phosphatase 3 | [424] | 1.83[425] | 2.61[426] | 3.07[427] | 1.85[428] | 2.74[429] | -0.86[430] |
63 | PRKX | cAMP-dependent protein kinase catalytic subunit PRKX | [431] | -1.75[432] | -2.35[433] | 3.00[434] | 1.17[435] | 2.76[436] | 2.00[437] |
64 | ADCY7 | Adenylate cyclase type 7 | [438] | 3.41[439] | 2.66[440] | 2.04[441] | 3.23[442] | 2.75[443] | 3.48[444] |
65 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [445] | 1.62[446] | 1.26[447] | 2.53[448] | 3.09[449] | 2.15[450] | 3.23[451] |
66 | AKT3 | RAC-gamma serine/threonine-protein kinase | [452] | -1.95[453] | -4.88[454] | -3.76[455] | 5.76[456] | 4.76[457] | 4.17[458] |
67 | MAPK11 | Mitogen-activated protein kinase 11 | [459] | -0.27[460] | -0.75[461] | -1.21[462] | 0.27[463] | 2.32[464] | 0.72[465] |
68 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | [466] | -7.27[467] | [468] | -2.58[469] | -4.00[470] | -3.61[471] | 2.90[472] |
69 | RPS6KA6 | Ribosomal protein S6 kinase alpha-6 | [473] | [474] | [475] | [476] | [477] | [478] | [479] |
70 | ADCY3 | Adenylate cyclase type 3 | [480] | 1.36[481] | -0.26[482] | 3.49[483] | 4.66[484] | 6.23[485] | 4.07[486] |
71 | SPDYA | Speedy protein A | [487] | -0.70[488] | 0.27[489] | -0.29[490] | 1.14[491] | -0.35[492] | 1.28[493] |
72 | ADCY2 | Adenylate cyclase type 2 | [494] | -5.48[495] | -3.92[496] | -4.75[497] | -2.81[498] | -3.89[499] | -3.56[500] |
73 | CCNB3 | G2/mitotic-specific cyclin-B3 | [501] | -1.77[502] | -2.88[503] | -2.72[504] | -1.98[505] | 0.92[506] | 2.40[507] |
74 | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | [508] | [509] | [510] | 1.26[511] | -3.58[512] | 4.66[513] | |
75 | ADCY5 | Adenylate cyclase type 5 | [514] | 0.05[515] | 0.68[516] | 2.13[517] | 0.57[518] | 1.74[519] | 6.93[520] |
76 | CPEB1 | Cytoplasmic polyadenylation element-binding protein 1 | [521] | 1.67[522] | -1.50[523] | -2.81[524] | 6.78[525] | 5.26[526] | 4.48[527] |
77 | PDE3A | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | [528] | 1.73[529] | 3.52[530] | 8.68[531] | 3.50[532] | 4.87[533] | 7.11[534] |
78 | CCNA1 | Cyclin-A1 | [535] | [536] | -3.86[537] | [538] | -0.87[539] | 6.58[540] | [541] |
79 | ADCY4 | Adenylate cyclase type 4 | [542] | -0.01[543] | -1.45[544] | 1.61[545] | [546] | [547] | 8.93[548] |
80 | MAPK10 | Mitogen-activated protein kinase 10 | [549] | -1.59[550] | [551] | [552] | 8.83[553] | 4.61[554] | 7.80[555] |
81 | ADCY8 | Adenylate cyclase type 8 | [556] | [557] | [558] | [559] | [560] | [561] | [562] |
82 | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | [563] | [564] | [565] | [566] | [567] | [568] | [569] |
83 | INS | Insulin | [570] | [571] | [572] | [573] | [574] | [575] | [576] |
84 | MOS | Proto-oncogene serine/threonine-protein kinase mos | [577] | [578] | [579] | [580] | [581] | [582] | [583] |
85 | PGR | Progesterone receptor | [584] | [585] | [586] | [587] | [588] | [589] | [590] |