KEGG_PRIMARY_IMMUNODEFICIENCY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | IKBKG | NF-kappa-B essential modulator | [1] | -0.46[2] | -0.19[3] | -2.18[4] | -1.10[5] | -1.64[6] | -0.28[7] |
2 | CD4 | T-cell surface glycoprotein CD4 | [8] | -5.32[9] | -3.03[10] | -5.40[11] | -7.70[12] | -9.09[13] | 0.24[14] |
3 | UNG | Uracil-DNA glycosylase | [15] | 0.94[16] | 1.02[17] | 1.70[18] | -1.36[19] | 0.06[20] | -0.77[21] |
4 | TAP1 | Antigen peptide transporter 1 | [22] | 0.31[23] | -0.59[24] | -4.04[25] | 1.34[26] | 0.38[27] | -0.34[28] |
5 | IGLL1 | Immunoglobulin lambda-like polypeptide 1 | [29] | [30] | [31] | -10.99[32] | [33] | -12.34[34] | -8.63[35] |
6 | TAP2 | Antigen peptide transporter 2 | [36] | 0.79[37] | -0.40[38] | -1.63[39] | 1.76[40] | 1.36[41] | -0.07[42] |
7 | RFXANK | DNA-binding protein RFXANK | [43] | 0.26[44] | 0.10[45] | 1.77[46] | -0.77[47] | 0.26[48] | -1.50[49] |
8 | BLNK | B-cell linker protein | [50] | -9.17[51] | -9.19[52] | -6.60[53] | -10.54[54] | -8.43[55] | 0.24[56] |
9 | CD40 | Tumor necrosis factor receptor superfamily member 5 | [57] | -0.37[58] | -1.45[59] | -9.44[60] | -3.07[61] | -1.07[62] | -0.61[63] |
10 | RFX5 | DNA-binding protein RFX5 | [64] | 1.70[65] | 2.16[66] | 2.46[67] | 1.52[68] | 2.38[69] | 1.03[70] |
11 | ADA | Adenosine deaminase | [71] | 1.59[72] | 0.85[73] | -0.91[74] | 1.67[75] | -0.22[76] | -0.69[77] |
12 | IL2RG | Cytokine receptor common subunit gamma | [78] | -1.22[79] | -2.99[80] | -2.09[81] | -3.85[82] | [83] | 0.22[84] |
13 | PTPRC | Receptor-type tyrosine-protein phosphatase C | [85] | [86] | [87] | [88] | 0.12[89] | -8.13[90] | 3.47[91] |
14 | DCLRE1C | Protein artemis | [92] | 0.70[93] | 2.32[94] | 1.74[95] | 2.39[96] | 1.86[97] | 1.78[98] |
15 | CD79A | B-cell antigen receptor complex-associated protein alpha chain | [99] | -0.50[100] | -2.05[101] | -3.78[102] | -4.77[103] | -4.26[104] | -0.35[105] |
16 | RFXAP | Regulatory factor X-associated protein | [106] | 1.82[107] | 1.93[108] | 1.81[109] | 0.17[110] | 1.89[111] | 0.50[112] |
17 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | [113] | -8.43[114] | [115] | -4.58[116] | [117] | [118] | -0.28[119] |
18 | IL7R | Interleukin-7 receptor subunit alpha | [120] | -3.80[121] | -4.28[122] | -4.11[123] | 4.99[124] | 5.57[125] | 2.54[126] |
19 | CD3D | T-cell surface glycoprotein CD3 delta chain | [127] | 1.83[128] | -0.07[129] | -2.18[130] | -6.75[131] | -4.09[132] | 0.00[133] |
20 | LCK | Tyrosine-protein kinase Lck | [134] | 3.21[135] | 3.40[136] | -6.33[137] | -5.33[138] | -4.87[139] | 1.56[140] |
21 | CD8A | T-cell surface glycoprotein CD8 alpha chain | [141] | -0.19[142] | -3.84[143] | 1.56[144] | -4.93[145] | -2.90[146] | 1.16[147] |
22 | JAK3 | Tyrosine-protein kinase JAK3 | [148] | 2.68[149] | 5.07[150] | -0.68[151] | -0.88[152] | 0.52[153] | 3.42[154] |
23 | BTK | Tyrosine-protein kinase BTK | [155] | -6.95[156] | [157] | 0.27[158] | -3.26[159] | -4.82[160] | 2.15[161] |
24 | ZAP70 | Tyrosine-protein kinase ZAP-70 | [162] | 1.43[163] | 1.77[164] | -4.20[165] | -5.79[166] | -3.78[167] | 2.48[168] |
25 | CIITA | MHC class II transactivator | [169] | -1.96[170] | -2.02[171] | -3.67[172] | -0.90[173] | 0.92[174] | 3.23[175] |
26 | CD40LG | CD40 ligand | [176] | -4.34[177] | [178] | -5.62[179] | -4.49[180] | [181] | -0.25[182] |
27 | RAG1 | V(D)J recombination-activating protein 1 | [183] | 0.35[184] | 0.71[185] | 3.18[186] | 2.70[187] | 1.11[188] | 2.94[189] |
28 | AIRE | Autoimmune regulator | [190] | [191] | -1.80[192] | -3.78[193] | -3.13[194] | -2.81[195] | -3.29[196] |
29 | CD19 | B-lymphocyte antigen CD19 | [197] | 2.54[198] | 4.35[199] | -0.22[200] | -1.72[201] | [202] | 1.39[203] |
30 | AICDA | Single-stranded DNA cytosine deaminase | [204] | 1.09[205] | 1.88[206] | 1.70[207] | 0.17[208] | 0.84[209] | 1.34[210] |
31 | RAG2 | V(D)J recombination-activating protein 2 | [211] | -0.61[212] | -1.98[213] | -1.05[214] | -0.91[215] | 0.10[216] | 0.27[217] |
32 | ICOS | Inducible T-cell costimulator | [218] | [219] | -2.83[220] | [221] | [222] | [223] | -0.23[224] |
33 | CD8B | T-cell surface glycoprotein CD8 beta chain | [225] | 1.42[226] | -0.10[227] | 8.75[228] | [229] | -1.59[230] | 3.45[231] |
34 | TNFRSF13 | Tumor necrosis factor receptor superfamily member 13B | [232] | [233] | [234] | [235] | [236] | [237] | 2.19[238] |
35 | TNFRSF13 | Tumor necrosis factor receptor superfamily member 13C | [239] | [240] | [241] | [242] | [243] | [244] | [245] |