KEGG_PHENYLALANINE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HPD 4-hydroxyphenylpyruvate dioxygenase [1] -0.28[2] -0.13[3] -9.95[4] -6.36[5] -8.79[6] -1.22[7]
2 MIF Macrophage migration inhibitory factor [8] [9] [10] [11] [12] [13] [14]
3 PRDX6 Peroxiredoxin-6 [15] 0.96[16] 0.37[17] 1.09[18] 2.28[19] 1.49[20] -0.53[21]
4 PAH Phenylalanine-4-hydroxylase [22] 0.18[23] 0.67[24] 1.37[25] -7.29[26] -7.70[27] 0.88[28]
5 TAT Tyrosine aminotransferase [29] -4.85[30] -2.97[31] -4.69[32] -7.54[33] -8.61[34] 2.16[35]
6 GOT1 Aspartate aminotransferase, cytoplasmic [36] 1.18[37] 2.00[38] 1.23[39] -0.76[40] -0.29[41] 0.70[42]
7 GOT2 Aspartate aminotransferase, mitochondrial [43] 2.06[44] 0.80[45] 1.76[46] 1.33[47] 1.93[48] 1.02[49]
8 MAOB Amine oxidase [flavin-containing] B [50] 0.11[51] -1.12[52] 0.32[53] 0.85[54] -7.32[55] 0.30[56]
9 MAOA Amine oxidase [flavin-containing] A [57] -0.72[58] -0.76[59] 2.28[60] -1.57[61] 3.15[62] 1.80[63]
10 DDC Aromatic-L-amino-acid decarboxylase [64] 0.40[65] 0.78[66] 2.96[67] -4.13[68] -5.63[69] 0.46[70]
11 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring [71] -0.03[72] -4.98[73] -1.62[74] 1.30[75] -2.21[76] -2.27[77]
12 ALDH3B1 Aldehyde dehydrogenase family 3 member B1 [78] 4.35[79] 3.61[80] 3.94[81] 7.83[82] 5.49[83] 0.22[84]
13 AOC3 Membrane primary amine oxidase [85] 4.36[86] 5.93[87] 3.41[88] 1.66[89] 1.13[90] 2.43[91]
14 AOC2 Retina-specific copper amine oxidase [92] 2.79[93] 2.76[94] 4.97[95] 3.92[96] 3.53[97] 0.77[98]
15 IL4I1 L-amino-acid oxidase [99] -2.28[100] -4.01[101] -0.10[102] 2.97[103] 0.44[104] -1.01[105]
16 ALDH1A3 Aldehyde dehydrogenase family 1 member A3 [106] 2.63[107] -2.21[108] 1.16[109] 7.12[110] 11.78[111] 4.00[112]
17 ALDH3B2 Aldehyde dehydrogenase family 3 member B2 [113] [114] [115] [116] [117] [118] [119]
18 NAA80 [120] [121] [122] [123] [124] [125] [126]
[1]
ref_hepatocyte HPD
Mean 473
Standard deviation 3e+02
Values 2.3e+02 5.5e+02 6.6e+02 1.1e+02 8.2e+02
[2]
HepG2 HPD
Mean 154
Standard deviation 24
Values 1.4e+02 1.7e+02
[3]
HepG2.C3A HPD
Mean 270
Standard deviation 6.6
Values 2.7e+02 2.7e+02
[4]
HuH.7 HPD
Mean 0.167
Standard deviation 0.047
Values 0.11 0.18 0.21
[5]
SNU475 HPD
Mean 1.26
Standard deviation 0.42
Values 1.6 0.96
[6]
THLE HPD
Mean 0.361
Standard deviation 0.24
Values 0.19 0.53
[7]
liver HPD
Mean 235
Standard deviation 86
Values 2e+02 2.5e+02 3.5e+02 1.4e+02
[8]
ref_hepatocyte MIF
Mean 318
Standard deviation 1.7e+02
Values 1.2e+02 1.9e+02 5.1e+02 4.5e+02 3.3e+02
[9]
HepG2 MIF
Missing
[10]
HepG2.C3A MIF
Missing
[11]
HuH.7 MIF
Missing
[12]
SNU475 MIF
Missing
[13]
THLE MIF
Missing
[14]
liver MIF
Missing
[15]
ref_hepatocyte PRDX6
Mean 164
Standard deviation 95
Values 1.6e+02 1.2e+02 2.5e+02 31 2.6e+02
[16]
HepG2 PRDX6
Mean 126
Standard deviation 7.3
Values 1.2e+02 1.3e+02
[17]
HepG2.C3A PRDX6
Mean 132
Standard deviation 3.4
Values 1.3e+02 1.3e+02
[18]
HuH.7 PRDX6
Mean 122
Standard deviation 18
Values 1.2e+02 1e+02 1.4e+02
[19]
SNU475 PRDX6
Mean 173
Standard deviation 58
Values 2.1e+02 1.3e+02
[20]
THLE PRDX6
Mean 155
Standard deviation 11
Values 1.5e+02 1.6e+02
[21]
liver PRDX6
Mean 130
Standard deviation 99
Values 58 2e+02 2.3e+02 33
[22]
ref_hepatocyte PAH
Mean 136
Standard deviation 1.9e+02
Values 42 11 1.6e+02 6.3 4.6e+02
[23]
HepG2 PAH
Mean 61
Standard deviation 30
Values 40 82
[24]
HepG2.C3A PAH
Mean 135
Standard deviation 6.2
Values 1.3e+02 1.4e+02
[25]
HuH.7 PAH
Mean 123
Standard deviation 14
Values 1.2e+02 1.1e+02 1.4e+02
[26]
SNU475 PAH
Mean 0.19
Standard deviation 0.12
Values 0.1 0.28
[27]
THLE PAH
Mean 0.219
Standard deviation 0.17
Values 0.34 0.096
[28]
liver PAH
Mean 289
Standard deviation 1.2e+02
Values 2.7e+02 4.3e+02 3.1e+02 1.5e+02
[29]
ref_hepatocyte TAT
Mean 98.7
Standard deviation 1.4e+02
Values 1.5 2 3e+02 8.6 1.8e+02
[30]
HepG2 TAT
Mean 1.36
Standard deviation 0.56
Values 1.8 0.97
[31]
HepG2.C3A TAT
Mean 7.84
Standard deviation 2.3
Values 9.4 6.2
[32]
HuH.7 TAT
Mean 1.34
Standard deviation 0.97
Values 0.76 2.5 0.8
[33]
SNU475 TAT
Mean 0.116
Standard deviation 0.013
Values 0.13 0.11
[34]
THLE TAT
Mean 0.0852
Standard deviation 0.03
Values 0.11 0.064
[35]
liver TAT
Mean 507
Standard deviation 1.5e+02
Values 4.6e+02 6.4e+02 6.1e+02 3.2e+02
[36]
ref_hepatocyte GOT1
Mean 75.1
Standard deviation 57
Values 6.4 44 1.5e+02 62 1.1e+02
[37]
HepG2 GOT1
Mean 67.6
Standard deviation 26
Values 86 49
[38]
HepG2.C3A GOT1
Mean 188
Standard deviation 68
Values 2.4e+02 1.4e+02
[39]
HuH.7 GOT1
Mean 61.7
Standard deviation 15
Values 65 45 75
[40]
SNU475 GOT1
Mean 9.68
Standard deviation 0.11
Values 9.6 9.8
[41]
THLE GOT1
Mean 20.6
Standard deviation 1.6
Values 20 22
[42]
liver GOT1
Mean 140
Standard deviation 1e+02
Values 1.1e+02 1.1e+02 2.8e+02 51
[43]
ref_hepatocyte GOT2
Mean 58.1
Standard deviation 35
Values 32 39 86 29 1e+02
[44]
HepG2 GOT2
Mean 96.4
Standard deviation 0.81
Values 96 97
[45]
HepG2.C3A GOT2
Mean 63.2
Standard deviation 7.6
Values 58 69
[46]
HuH.7 GOT2
Mean 69
Standard deviation 13
Values 80 55 72
[47]
SNU475 GOT2
Mean 31.9
Standard deviation 2.4
Values 34 30
[48]
THLE GOT2
Mean 74.4
Standard deviation 6.4
Values 70 79
[49]
liver GOT2
Mean 136
Standard deviation 87
Values 77 1.8e+02 2.4e+02 50
[50]
ref_hepatocyte MAOB
Mean 46.4
Standard deviation 48
Values 20 15 70 6.9 1.2e+02
[51]
HepG2 MAOB
Mean 19.9
Standard deviation 8.1
Values 14 26
[52]
HepG2.C3A MAOB
Mean 13.4
Standard deviation 5.7
Values 9.3 17
[53]
HuH.7 MAOB
Mean 20.3
Standard deviation 0.76
Values 21 21 19
[54]
SNU475 MAOB
Mean 18.4
Standard deviation 15
Values 29 7.7
[55]
THLE MAOB
Mean 0.0976
Standard deviation 0.012
Values 0.089 0.11
[56]
liver MAOB
Mean 66.2
Standard deviation 42
Values 35 1.1e+02 92 26
[57]
ref_hepatocyte MAOA
Mean 22.1
Standard deviation 16
Values 3.4 23 34 8.6 41
[58]
HepG2 MAOA
Mean 5.32
Standard deviation 0.22
Values 5.5 5.2
[59]
HepG2.C3A MAOA
Mean 8.16
Standard deviation 2.3
Values 9.8 6.5
[60]
HuH.7 MAOA
Mean 37.5
Standard deviation 10
Values 36 49 28
[61]
SNU475 MAOA
Mean 1.62
Standard deviation 0.75
Values 1.1 2.1
[62]
THLE MAOA
Mean 66.1
Standard deviation 1.4
Values 67 65
[63]
liver MAOA
Mean 88.9
Standard deviation 19
Values 90 1.1e+02 88 65
[64]
ref_hepatocyte DDC
Mean 16.2
Standard deviation 7.9
Values 20 15 19 3.1 24
[65]
HepG2 DDC
Mean 8.45
Standard deviation 3.2
Values 6.2 11
[66]
HepG2.C3A DDC
Mean 17.3
Standard deviation 4.6
Values 14 21
[67]
HuH.7 DDC
Mean 43.9
Standard deviation 9.4
Values 45 34 53
[68]
SNU475 DDC
Mean 0.201
Standard deviation 0.063
Values 0.25 0.16
[69]
THLE DDC
Mean 0.11
Standard deviation 0.087
Values 0.17 0.048
[70]
liver DDC
Mean 25.7
Standard deviation 11
Values 15 41 19 28
[71]
ref_hepatocyte ALDH3A1
Mean 2.58
Standard deviation 5.2
Values 12 0.4 0.24 0 0.37
[72]
HepG2 ALDH3A1
Mean 1
Standard deviation 0.21
Values 1.2 0.85
[73]
HepG2.C3A ALDH3A1
Mean 0.0511
Standard deviation 0.0036
Values 0.049 0.054
[74]
HuH.7 ALDH3A1
Mean 0.294
Standard deviation 0.089
Values 0.36 0.19 0.33
[75]
SNU475 ALDH3A1
Mean 1.39
Standard deviation 0.1
Values 1.3 1.5
[76]
THLE ALDH3A1
Mean 0.187
Standard deviation 0.07
Values 0.24 0.14
[77]
liver ALDH3A1
Mean 0.614
Standard deviation 0.76
Values 0.59 0.071 1.7 0.11
[78]
ref_hepatocyte ALDH3B1
Mean 1.3
Standard deviation 0.3
Values 1.8 1.2 1.1 1.2 1.2
[79]
HepG2 ALDH3B1
Mean 10.5
Standard deviation 1.5
Values 12 9.5
[80]
HepG2.C3A ALDH3B1
Mean 9.94
Standard deviation 4.7
Values 13 6.6
[81]
HuH.7 ALDH3B1
Mean 6.99
Standard deviation 0.87
Values 8 6.4 6.6
[82]
SNU475 ALDH3B1
Mean 64.9
Standard deviation 36
Values 91 39
[83]
THLE ALDH3B1
Mean 19.7
Standard deviation 1.7
Values 18 21
[84]
liver ALDH3B1
Mean 1.75
Standard deviation 0.18
Values 1.6 2 1.8 1.7
[85]
ref_hepatocyte AOC3
Mean 0.938
Standard deviation 0.67
Values 1.2 0 1.4 0.5 1.6
[86]
HepG2 AOC3
Mean 7.65
Standard deviation 3
Values 9.8 5.5
[87]
HepG2.C3A AOC3
Mean 35.8
Standard deviation 5.7
Values 40 32
[88]
HuH.7 AOC3
Mean 3.49
Standard deviation 0.42
Values 3.1 3.9 3.5
[89]
SNU475 AOC3
Mean 0.646
Standard deviation 0.46
Values 0.32 0.97
[90]
THLE AOC3
Mean 0.692
Standard deviation 0.44
Values 1 0.38
[91]
liver AOC3
Mean 5.85
Standard deviation 3.6
Values 4.7 2.7 11 5.1
[92]
ref_hepatocyte AOC2
Mean 0.43
Standard deviation 0.52
Values 0 0.36 0.53 1.3 0
[93]
HepG2 AOC2
Mean 1.18
Standard deviation 0.25
Values 1.4 1
[94]
HepG2.C3A AOC2
Mean 1.82
Standard deviation 0.54
Values 2.2 1.4
[95]
HuH.7 AOC2
Mean 4.72
Standard deviation 0.32
Values 4.4 4.7 5
[96]
SNU475 AOC2
Mean 1.42
Standard deviation 0.78
Values 0.87 2
[97]
THLE AOC2
Mean 1.67
Standard deviation 0.78
Values 2.2 1.1
[98]
liver AOC2
Mean 0.848
Standard deviation 0.61
Values 0.98 0.19 0.59 1.6
[99]
ref_hepatocyte IL4I1
Mean 0.263
Standard deviation 0.43
Values 0 0 0.078 1 0.22
[100]
HepG2 IL4I1
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[101]
HepG2.C3A IL4I1
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[102]
HuH.7 IL4I1
Mean 0.086
Standard deviation 0.025
Values 0.11 0.058 0.094
[103]
SNU475 IL4I1
Mean 0.452
Standard deviation 0.29
Values 0.25 0.66
[104]
THLE IL4I1
Mean 0.12
Standard deviation 0.011
Values 0.11 0.13
[105]
liver IL4I1
Mean 0.15
Standard deviation 0.14
Values 0.071 0.12 0.36 0.053
[106]
ref_hepatocyte ALDH1A3
Mean 0.115
Standard deviation 0.2
Values 0 0.47 0.043 0 0.065
[107]
HepG2 ALDH1A3
Mean 0.283
Standard deviation 0.2
Values 0.42 0.14
[108]
HepG2.C3A ALDH1A3
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[109]
HuH.7 ALDH1A3
Mean 0.0903
Standard deviation 0.069
Values 0.16 0.096 0.019
[110]
SNU475 ALDH1A3
Mean 3.5
Standard deviation 1.1
Values 2.7 4.3
[111]
THLE ALDH1A3
Mean 136
Standard deviation 53
Values 99 1.7e+02
[112]
liver ALDH1A3
Mean 2.13
Standard deviation 0.67
Values 2.4 1.3 1.9 2.9
[113]
ref_hepatocyte ALDH3B2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 ALDH3B2
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[115]
HepG2.C3A ALDH3B2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[116]
HuH.7 ALDH3B2
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[117]
SNU475 ALDH3B2
Mean 0.0312
Standard deviation 0.0083
Values 0.037 0.025
[118]
THLE ALDH3B2
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[119]
liver ALDH3B2
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[120]
ref_hepatocyte NAA80
Missing
[121]
HepG2 NAA80
Missing
[122]
HepG2.C3A NAA80
Missing
[123]
HuH.7 NAA80
Missing
[124]
SNU475 NAA80
Missing
[125]
THLE NAA80
Missing
[126]
liver NAA80
Missing